Mild conditions for Pd-catalyzed carboamination of N-protected hex-4-enylamines and 1-, 3-, and 4-substituted pent-4-enylamines. Scope, limitations, and mechanism of pyrrolidine formation

Journal of Organic Chemistry

Volumn 73, Issue 22, 2008, Pages 8851-8860

  Bertrand, Myra Beaudoin ^a,b   Neukom, Joshua D ^a   Wolfe, John P ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

^b BRISTOL MYERS SQUIBB   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BROMINE COMPOUNDS; CESIUM; CHEMICAL REACTIONS; DEUTERIUM; ESTERS; FUNCTIONAL GROUPS; KETONES; OLEFINS; ORGANIC COMPOUNDS; PALLADIUM; PALLADIUM COMPOUNDS; STEREOCHEMISTRY;

AMINOPALLADATION; ARYL BROMIDES; ARYL GROUPS; CHEMICAL EQUATIONS; DIASTEREO SELECTIVITIES; GOOD YIELDS; HIGH YIELDS; MILD CONDITIONS; NITRO GROUPS; NITROGEN ATOMS; PYRROLIDINE; PYRROLIDINES; REACTION CONDITIONS; STEREOSPECIFICALLY; WEAK BASE;

GROUP TECHNOLOGY;

ALKENE; ALKENE DERIVATIVE; AMINE; BROMINE DERIVATIVE; CARBON; CESIUM; DEUTERIUM; ESTER DERIVATIVE; FUNCTIONAL GROUP; KETONE DERIVATIVE; NITROGEN; OXYGEN; PALLADIUM; PROLINE DERIVATIVE;

AMINATION; ARTICLE; COMPLEX FORMATION; REACTION ANALYSIS; STEREOCHEMISTRY; SUBSTITUTION REACTION;

ALKENES; AMINATION; AMINES; CATALYSIS; DEUTERIUM; ISOQUINOLINES; NITROGEN; PALLADIUM; PYRROLIDINES; STAINING AND LABELING;

EID: 56449098619     PISSN: 00223263     EISSN: None     Source Type: Journal    
DOI: 10.1021/jo801631v     Document Type: Article

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