Anti-inflammatory effects of 7-methoxycryptopleurine and structure-activity relations of phenanthroindolizidines and phenanthroquinolizidines

Biochemical and Biophysical Research Communications

Volumn 354, Issue 4, 2007, Pages 942-948

  Yang, Cheng Wei ^a   Chuang, Ta Hsien ^b   Wu, Pei Lin ^c   Huang, Wen Hsin ^d   Lee, Shiow Ju ^a  

^a NATIONAL HEALTH RESEARCH INSTITUTES   (Taiwan)

^b NATIONAL CHENG KUNG UNIVERSITY   (Taiwan)

^c CHUNG HWA UNIVERSITY OF MEDICAL TECHNOLOGY   (Taiwan)

^d NATIONAL DEFENSE MEDICAL CENTER   (Taiwan)

Author keywords

Anti cancer; Anti inflammation; Cryptopleurine; HONE 1; IFN ; Inducible nitric oxide synthase; iNOS; LPS; Nitric oxide; NO; NUGC 3; Phenanthroindolizidine; Phenanthroquinolizidine; RAW264.7; Tylophorine

Indexed keywords

10,11,12,13 TETRAHYDRO 9A AZABENZO[B]TRIPHENYLEN 9 ONE; 10,11,12,13 TETRAHYDRO 9A AZONIABENZO[B]TRIPHENYLENE BROMIDE; 10,11,12,13,13A,14 HEXAHYDRO 9A AZABENZO[B]TRIPHENYLEN 9 ONE; 10,11,12,13,13A,14 HEXAHYDRO 9A AZABENZO[B]TRIPHENYLENE; 2,3,6,7 TETRAMETHOXY 11,12 DIHYDRO 10H 9A AZACYCLOPENTA[B]TRIPHENYLEN 9 ONE; 7 METHOXYCRYPTOPLEURINE; ALKALOID DERIVATIVE; AMIDE; AMINE; DEHYDROTYLOPHORINE; INDOLIZIDINE DERIVATIVE; INDOMETACIN; PHENANTHRENE; PHENANTHROINDOLIZIDINE; PHENANTHROQUINOLIZIDINE; QUINOLIZIDINE DERIVATIVE; TYLOPHORIN 9 ONE; TYLOPHORINE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIINFLAMMATORY ACTIVITY; ARTICLE; CANCER CELL; CONTROLLED STUDY; CYTOTOXICITY; DRUG ACTIVITY; DRUG MECHANISM; DRUG STRUCTURE; DRUG SYNTHESIS; FEMALE; MALE; MOUSE; NONHUMAN; PAW EDEMA; PRIORITY JOURNAL; RIGIDITY;

ALKALOIDS; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; ANTINEOPLASTIC AGENTS; CELL LINE, TUMOR; CYCLOOXYGENASE 2; HUMANS; INDOLIZINES; MACROPHAGES; MICE; NITRIC OXIDE SYNTHASE TYPE II; PHENANTHRENES; QUINOLIZINES; STRUCTURE-ACTIVITY RELATIONSHIP; TUMOR NECROSIS FACTOR-ALPHA;

EID: 33846850368     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2007.01.065     Document Type: Article

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