Mild conditions for the synthesis of functionalized pyrrolidines via Pd-catalyzed carboamination reactions

Organic Letters

Volumn 9, Issue 3, 2007, Pages 457-460

  Bertrand, Myra Beaudoin ^a   Leathen, Matthew L ^a   Wolfe, John P ^a  

^a UNIVERSITY OF MICHIGAN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,4-DIOXANE; ACETIC ACID DERIVATIVE; ALKENE; BROMINATED HYDROCARBON; CARBONIC ACID DERIVATIVE; CESIUM; DIOXANE; DIOXANE DERIVATIVE; ESTER; KETONE; MESYLIC ACID DERIVATIVE; NITRO DERIVATIVE; PALLADIUM; PYRROLIDINE DERIVATIVE; SOLVENT; TRIFLUOROMETHANESULFONIC ACID; UNCLASSIFIED DRUG;

AMINATION; ARTICLE; CATALYSIS; CHEMICAL MODEL; CHEMISTRY; SYNTHESIS;

ACETATES; ALKENES; AMINATION; CARBONATES; CATALYSIS; CESIUM; DIOXANES; ESTERS; HYDROCARBONS, BROMINATED; KETONES; MESYLATES; MODELS, CHEMICAL; NITRO COMPOUNDS; PALLADIUM; PYRROLIDINES; SOLVENTS;

EID: 33847074190     PISSN: 15237060     EISSN: None     Source Type: Journal    
DOI: 10.1021/ol062808f     Document Type: Article

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27. These conditions were also less effective for carboamination reactions of γ-(N-arylamino)alkenes; the desired N-arylpyrrolidine products were obtained in low to moderate yield (35-55%).