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Volumn 66, Issue 7, 1994, Pages 1423-1430

Application of intramolecular Heck reactions for forming congested Quaternary carbon centers in complex molecule total synthesis

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EID: 84942221470     PISSN: 00334545     EISSN: 13653075     Source Type: Journal    
DOI: 10.1351/pac199466071423     Document Type: Article
Times cited : (165)

References (25)
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    • for leading references to other asymmetric Heck reactions, see: (a) (b) F. Ozawa, Y. Kobatake and T. Hayashi, Tetrahedron Lett. 34. 2505 (1993). For a brief review, see: (c) M. Shibasaki, Y. Sato, K. Kagechika. J. Svnth. Org. Chem. Japan 50. 26 (1992).
    • For leading references to other asymmetric Heck reactions, see: (a) S. Nakui, M. Sodeoka and M. Shibasaki, Tetrahedron Lett. 34. 4965 (1992). (b) F. Ozawa, Y. Kobatake and T. Hayashi, Tetrahedron Lett. 34. 2505 (1993). For a brief review, see: (c) M. Shibasaki, Y. Sato, K. Kagechika. J. Svnth. Org. Chem. Japan 50. 26 (1992).
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    • for a review of alkaloids of the Calabar bean, see: (a) For recent reviews of pharmacology, see: (b) A. Brossi. J. Med. Chem. 33. 2311 (1990). (c) M. Sano, K. Bell, K. Marder and L. Stricks. Clinical Pharm. 16. 61 (1993).
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    • The synthesis of a racemic hexahydropyrrolo[2,3-b]indole by intramolecular Heck cyclization of a pyrrolidine-2-one aminal has been described by Hoffmann, see
    • The synthesis of a racemic hexahydropyrrolo[2,3-b]indole by intramolecular Heck cyclization of a pyrrolidine-2-one aminal has been described by Hoffmann, see: H. M. R. Hoffman, B. Schmidt and S. Wolff, Tetrahedron 45, 6113 (1989).
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    • B. M. Trost and I. Fleming, Eds., Pergamon, Oxford, Vol. 5, Chapter 8.2
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    • (1991) In Comprehensive Organic Synthesis
    • Piers, E.1


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