Loss of the CONSTITUTIVE PHOTOMORPHOGENIC9 signalosome subunit 5 is sufficient to cause the cop/det/fus mutant phenotype in Arabidopsis

Plant Cell

Volumn 17, Issue 7, 2005, Pages 1967-1978

  Dohmann, Esther M N ^a   Kuhnle, Carola ^a   Schwechheimer, Claus ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; ENZYMES;

ARABIDOPSIS THALIANA; DENEDDYLATION; MUTANT PHENOTYPES;

PLANT CELL CULTURE;

CELLS; ENZYMES; PHENOTYPES; PLANTS;

ARABIDOPSIS; ARABIDOPSIS THALIANA;

ARABIDOPSIS PROTEIN; CARRIER PROTEIN; CELL CYCLE PROTEIN; CONSTITUTIVE PHOTOMORPHOGENIC 9 PROTEIN, ARABIDOPSIS; CULLIN; CULLIN 1; CULLIN 3A PROTEIN, ARABIDOPSIS; UBIQUITIN; UBIQUITIN PROTEIN LIGASE;

ARABIDOPSIS; ARTICLE; GENE EXPRESSION REGULATION; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MUTATION; PHENOTYPE;

ARABIDOPSIS; ARABIDOPSIS PROTEINS; CARRIER PROTEINS; CELL CYCLE PROTEINS; CULLIN PROTEINS; GENE EXPRESSION REGULATION, PLANT; MUTATION; PHENOTYPE; UBIQUITIN; UBIQUITIN-PROTEIN LIGASES;

EID: 27144492877     PISSN: 10404651     EISSN: None     Source Type: Journal    
DOI: 10.1105/tpc.105.032870     Document Type: Article

References (61)

1. Alonso, J.M., et al. (2003). Genome-wide insertional mutagenesis of Arabidopsis thaliana. Science 301, 633-657.
2. Chamovitz, D.A., Wei, N., Osterlund, M.T., von Arnim, A.G., Staub, J.M., Matsui, M., and Deng, X.-W. (1996). The COP9 complex, a novel multisubunit nuclear regulator involved in light control of a plant developmental switch. Cell 86, 115-121.
3. Chiba, T., and Tanaka, K. (2004). Cullin-based ubiquitin ligase and its control by NEDD8-conjugating system. Curr. Protein Pept. Sci. 5, 177-184.
4. Cope, G.A., Suh, G.S.B., Aravind, L., Schwarz, S.E., Zipursky, S.L., Koonin, E.V., and Deshaies, R.J. (2002). Role for predicted metalloprotease motif of JAB1/Csn5 in cleavage of NEDD8 from CUL1. Science 298, 608-611.
5. Deshaies, R.J. (1999). SCF and Cullin/RING H2-based ubiquitin ligases. Annu. Rev. Cell Dev. Biol. 15, 435-467.
6. Dieterle, M., Thomann, A., Renou, J.-P., Parmentier, Y., Cognat, V., Lemonnier, G., Müller, R., Shen, W.-H., Kretsch, T., and Genschik, P. (2005). Molecular and functional characterization of Arabidopsis Cullin 3A. Plant J. 41, 386-399.
7. COI1 and modulates jasmonate responses. Plant Cell 15, 1083-1094.
8. Gagne, J.M., Downes, B.P., Shiu, S.H., Durski, A.M., and Vierstra, R.D. (2002). The F-box subunit of the SCF E3 complex is encoded by a diverse superfamily of genes in Arabidopsis. Proc. Natl. Acad. Sci. USA 99, 11519-11524.
9. Gray, W.M., del Pozo, J.C., Walker, L., Hobble, L., Risseeuw, E., Banks, T., Crosby, W.L., Yang, M., and Estelle, M. (1999). Identification of an SCF ubiquitin-ligase complex required for auxin response in Arabidopsis thaliana. Genes Dev. 13, 1678-1687.
10. TIR1-dependent degradation of AUX/IAA proteins. Nature 414, 271-276.
11. Groisman, R., Polanowska, J., Kuraoka, I., Sawada, J.-i., Siaijo, M., Tanaka, K., and Nakatani, Y. (2003). The ubiquitin ligase activity in the DDB2 and CSA complexes is differentially regulated by the COP9 signalosome in response to DNA damage. Cell 113, 357-367.
12. Gusmaroli, G., Feng, S., and Deng, X. (2004). The Arabidopsis CSN5A and CSN5B subunits are present in distinct COP9 signalosome complexes, and mutations in their JAMM domains exhibit differential dominant negative effects on development. Plant Cell 16, 2984-3001.
13. Hershko, A., and Chiechanover, A. (1998). The ubiquitin system. Annu. Rev. Biochem. 67, 425-479.
14. Higa, L.A.A., Mihaylov, I.S., Banks, D.P., Zhneg, J., and Zhang, H. (2003). Radiation-mediated proteolysis of CDT1 by CUL4-ROC1 and CSN complexes constitutes a new checkpoint. Nat. Cell Biol. 5, 1008-1015.
15. Ho, S.N., Hunt, H.D., Horton, R.M., Fuller, J.K., and Pease, L.R. (1989). Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77, 51-59.
16. Holm, M., Ma, L., Qu, L.-J., and Deng, X.W. (2002). Two interacting bZIP proteins are direct targets of COP1-mediated control of light-dependent gene expression in Arabidopsis. Genes Dev. 16, 1247-1259.
17. Hori, T., Osaka, F., Chiba, T., Miyamoto, C., Okabayashi, K., Shimbara, N., Kato, S., and Tanaka, K. (1999). Covalent modification of all members of human cullin family proteins by NEDD8. Oncogene 18, 6829-6834.
18. Kamura, T., Koepp, D.M., Conrad, M.N., Skowyra, D., Moreland, R.J., Iliopoulos, O., Lane, W.S., Kaelin, W.G.J., Elledge, S.J., Conaway, R.C., Harper, J.W., and Conaway, J.W. (1999). RBX1, a component of the VHL tumor suppressor complex and SCF ubiquitin ligase. Science 284, 657-661.
19. Karniol, B., Malec, P., and Chamovitz, D.A. (1999). Arabidopsis FUSCA5 encodes a novel phosphoprotein that is a component of the COP9 complex. Plant Cell 11, 839-848.
20. Komari, T., Hiei, Y., Saito, Y., Murai, N., and Kumashiro, T. (1996). Vectors carrying two separate T-DNAs for co-transformation of higher plants mediated by Agrobacterium tumefaciens and segregation of transformants free from selection markers. Plant J. 10, 165-174.
21. Kwok, S.F., Piekos, B., Miséra, S., and Deng, X.-W. (1996). A complement of ten essential and pleiotropic Arabidopsis COP/DET/ FUS genes is necessary for repression of photomorphogenesis in darkness. Plant Physiol. 110, 731-742.
22. Kwok, S.F., Solano, R., Tsuge, T., Chamovitz, D.A., Ecker, J.R., Matsui, M., and Deng, X.-W. (1998). Arabidopsis homologs of a c-Jun coactivator are present both in monomeric form and in the COP9 complex, and their abundance is differentially affected by the pleiotropic cop/det/fus mutations. Plant Cell 10, 1779-1790.
23. Liu, C., Powell, K.A., Mundt, K., Wu, L., Carr, A.M., and Caspari, T. (2003). Cop9/signalosome subunits and Pcu4 regulate ribonucletide reductase by both checkpoint-dependent and -independent mechanisms. Genes Dev. 17, 1130-1140.
24. Liu, Y.-C., Schiff, M., Serino, G., Deng, X.-W., and Dinesh-Kumar, S.P. (2002). Role of SCF ubiquitin-ligase and the COP9 signalosome in the N gene-mediated resistance response to tobacco mosaic virus. Plant Cell 14, 1483-1496.
25. Lyapina, S., Cope, G., Shevchenko, A., Serino, G., Zhou, C., Wolf, D.A., Wei, N., Shevchenko, A., and Deshaies, R.J. (2001). COP9 signalosome promotes cleavage of NEDD8-CUL1 conjugates. Science 292, 1382-1385.
26. Miséra, S., Müller, A.J., Weiland-Heidecker, U., and Jürgens, G. (1994). The FUSCA genes of Arabidopsis: Negative regulators of light responses. Mol. Gen. Genet. 244, 242-252.
27. Oron, E., Mannervik, M., Rencus, S., Harari-Steinberg, O., Neumann-Silberberg, S., Segal, D., and Chamovitz, D. (2002). COP9 signalosome subunits 4 and 5 regulate multiple pleiotropic pathways in Drosophila melanogaster. Development 129, 4399-4409.
28. Osterlund, M.T., Hardtke, C.S., Wei, N., and Deng, X.-W. (2000). Targeted destabilization of HY5 during light-regulated development of Arabidopsis. Nature 405, 462-466.
29. Pan, Z.Q., Kentsis, A., Dias, D.C., Yamoah, K., and Wu, K. (2004). Nedd8 on cullin: Building an expressway to protein destruction. Oncogene 23, 1985-1997.
30. Peng, Z., Serino, G., and Deng, X.-W. (2001a). Molecular characterization of subunit 6 of the COP9 signalosome and its role in multifaceted development processes in Arabidopsis. Plant Cell 13, 2393-2407.
31. Peng, Z., Serino, G., and Deng, X.-W. (2001b). A role of Arabidopsis COP9 signalosome in multifaceted developmental processes revealed by the characterization of its subunit 3. Development 128, 4277-4288.
32. Peng, Z., Shen, Y., Feng, S., Wang, X., Chittetei, B.N., Vierstra, R.D., and Deng, X.W. (2003). Evidence for a physical association of the COP9 signalosome, the proteasome, and specific SCF E3 ligases in vivo. Curr. Biol. 13, R504-R505.
33. Pintard, L., Kurz, T., Glaser, S., Willis, J.H., Peter, M., and Bowerman, B. (2003). Neddylation and deneddylation of CUL-3 is required to target MEI-1/katanin for degradation at the meiosis-tomitosis transition in C. elegans. Curr. Biol. 13, 911-921.
34. Risseeuw, E.P., Daskalchuk, T.E., Banks, T.W., Liu, E., Cotelesage, J., Hellmann, H., Estelle, M., Somers, D.E., and Crosby, W.L. (2003). Protein interaction analysis of SCF ubiquitin E3 ligase subunits from Arabidopsis. Plant J. 34, 753-767.
35. Schroeder, D.F., Gahrtz, M., Maxwell, B.B., Cook, R.K., Kan, J.M., Alonso, J.M., Ecker, J.R., and Chory, J. (2002). De-Etiolated 1 and Damaged DNA Binding Protein 1 interact to regulate Arabidopsis photomorphogenesis. Curr. Biol. 12, 1462-1472.
36. Schwechheimer, C. (2004). The COP9 signalosome (CSN): An evolutionary conserved proteolysis regulator in eukaryotic development. Biochim. Biophys. Acta 1695, 45-54.
37. Schwechheimer, C., and Deng, X. (2002). FPLC gel filtration. In Arabidopsis: A Laboratory Manual, D. Weigel and J. Glazebrook, eds (Cold Spring Harbor, NY: Cold Spring Harbor Laboratory Press), pp. 226-228.
38. TIR1 in mediating auxin response. Science 292, 1379-1382.
39. Schwechheimer, C., Serino, G., and Deng, X.-W. (2002). Multiple ubiquitin-ligase-mediated processes require COP9 signalosome and AXR1 function. Plant Cell 14, 2553-2563.
40. Schwechheimer, C., and Villalobos, L.I. (2004). Cullin-containing E3 ubiquitin ligases in plant development. Curr. Opin. Plant Biol. 7, 677-686.
41. Seeger, M., Kraft, R., Ferrell, K., Bech-Otschir, D., Dumdy, R., Schade, R., Gordon, C., Naumann, M., and Dubiel, W. (1998). A novel protein complex involved in signal transduction possessing similarities to 26S proteasome subunits. FASEB J. 12, 469-478.
42. Serino, G., Su, H., Peng, Z., Tsuge, T., Wei, N., Gu, H., and Deng, X.W. (2003). Characterization of the last subunit of the Arabidopsis COP9 signalosome: Implications for the overall structure and origin of the complex. Plant Cell 15, 719-731.
43. Serino, G., Tsuge, T., Kwok, S., Matsui, M., Wei, N., and Deng, X.-W. (1999). Arabidopsis cop8 and fus4 mutations define the same gene that encodes subunit 4 of the COP9 signalosome. Plant Cell 11, 1967-1979.
44. Shen, W.-H., Parmentier, Y., Hellmann, H., Lechner, E., Dong, A., Masson, J., Granier, F., Lepiniec, L., Estelle, M., and Genschik, P. (2002). Null mutation of AtCUL1 causes arrest in early embryogenesis in Arabidopsis. Mol. Biol. Cell 13, 1916-1928.
45. Staub, J.M., Wei, N., and Deng, X.-W. (1996). Evidence for FUS6 as a component of the nuclear-localized COP9 complex in Arabidopsis. Plant Cell 8, 2047-2056.
46. Tian, Q., and Reed, J.W. (1999). Control of auxin-regulated root development by the Arabidopsis thaliana SHY2/IAA3 gene. Development 126, 711-721.
47. Tomoda, K., Yoneda-Kato, N., Fukumoto, A., Yamanaka, S., and Kato, J.-y. (2004). Multiple functions of Jab1 are required for early embryonic development and growth potential in mice. J. Biol. Chem. 279,43013-43018.
48. Tran, H.J.T.T., Allen, M.D., Löwe, J., and Bycroft, M. (2003). Structure of the Jab1/MPN domain and its implications for proteasome function. Biochemistry 42, 11460-11465.
49. Ulmasov, T., Hagen, G., and Guilfoyle, T.J. (1997a). ARF1, a transcription factor that binds to auxin response elements. Science 276, 1865-1868.
50. Ulmasov, T., Murfett, J., Hagen, G., and Guilfoyle, T.J. (1997b). Aux/ IAA proteins repress expression of reporter genes containing natural and highly active synthetic auxin response elements. Plant Cell 9, 1963-1971.
51. Wang, K.L.-C., Yoshida, H., Lurin, C., and Ecker, J.R. (2004). Regulation of ethylene gas biosynthesis by the Arabidopsis ETO1 protein. Nature 428, 945-950.
52. Wang, X., Feng, S., Nakayama, N., Crosby, W.L., Irish, V.F., Deng, X.W., and Wei, N. (2003). The COP9 signalosome interacts with SCFUFO and participates in Arabidopsis flower development. Plant Cell 15, 1071-1082.
53. Weber, H., Bernhardt, A., Dieterle, M., Hano, P., Mutlu, A., Estelle, M., Genschik, P., and Hellmann, H. (2004). Arabidopsis AtCUL3a and AtCUL3b form complexes with members of the BTB/POZ-MATH protein family. Plant Physiol. 137, 83-93.
54. Wee, S., Geyer, R.K., Toda, T., and Wolf, D.A. (2005). CSN facilitates Cullin-RING ubiquitin ligase function by counteracting autocatalytic adapter stability. Nat. Cell Biol. 7, 387-391.
55. Wee, S., Hetfeld, B., Dubiel, W., and Wolf, D.A. (2002). Conservation of the COP9/signalosome in budding yeast. BMC Genet. 3, 15.
56. Wei, N., Chamovitz, D.A., and Deng, X.-W. (1994). Arabidopsis COP9 is a component of a novel signaling complex mediating light control of development. Cell 78, 117-124.
57. Wei, N., and Deng, X.W. (2003). The COP9 signalosome. Annu. Rev. Cell Dev. Biol. 19, 261-286.
58. Wertz, I.E., O'Rourke, K.M., Zhang, Z., Dornan, D., Arnott, D., Deshaies, R.J., and Dixit, V.M. (2004). Human De-Etiolated-1 regulates c-Jun by assembling a CUL4A ubiquitin ligase. Science 303, 1371-1374.
59. Wolf, D.A., Zhou, C., and Wee, S. (2003). The COP9 signalosome: An assembly and maintenance platform for cullin ubiquitin ligases? Nat. Cell Biol. 5, 1029-1033.
60. Xu, L., Wei, Y., Reboul, J., Vaglio, P., Shin, T.-H., Vidal, M., Elledge, S.J., and Harper, J.W. (2003). BTB proteins are substrate-specific adaptors in an SCF-like modular ubiquitin ligase containing Cul-3. Nature 425, 316-321.
61. Zhou, C., Seibert, V., Geyer, R., Rhee, E., Lyapina, S., Cope, G., Deshaies, R.J., and Wolf, D.A. (2001). The fission yeast COP9/ signalosome is involved in cullin modification by ubiquitin-related Ned8p. BMC Biochem. 2, 7.