-
1
-
-
0032547272
-
Induction of inhibitory Smad6 and Smad7 mRNA by TGF-β family members
-
Afrakhte, M., A. Moren, S. Jossan, S. Itoh, K. Sampath, B. Westermark, C.-H. Heldin, N. E. Heldin, and P. ten Dijke. 1998. Induction of inhibitory Smad6 and Smad7 mRNA by TGF-β family members. Biochem. Biophys. Res. Commun. 249:505-511.
-
(1998)
Biochem. Biophys. Res. Commun.
, vol.249
, pp. 505-511
-
-
Afrakhte, M.1
Moren, A.2
Jossan, S.3
Itoh, S.4
Sampath, K.5
Westermark, B.6
Heldin, C.-H.7
Heldin, N.E.8
Ten Dijke, P.9
-
2
-
-
0034104591
-
Smads as transcriptional co-modulators
-
Attisano, L., and J. L. Wrana. 2000. Smads as transcriptional co-modulators. Curr. Opin. Cell Biol. 12:235-243.
-
(2000)
Curr. Opin. Cell Biol.
, vol.12
, pp. 235-243
-
-
Attisano, L.1
Wrana, J.L.2
-
3
-
-
0037016769
-
Jab1 interacts directly with HIF-1α and regulates its stability
-
Bae, M. K., M. Y. Ahn, J. W. Jeong, M. H. Bae, Y. M. Lee, S. K. Bae, J. W. Park, K. R. Kim, and K. W. Kim. 2002. Jab1 interacts directly with HIF-1α and regulates its stability. J. Biol. Chem. 277:9-12.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 9-12
-
-
Bae, M.K.1
Ahn, M.Y.2
Jeong, J.W.3
Bae, M.H.4
Lee, Y.M.5
Bae, S.K.6
Park, J.W.7
Kim, K.R.8
Kim, K.W.9
-
4
-
-
0036472506
-
The COP9 signalosome: At the interface between signal transduction and ubiquitin-dependent proteolysis
-
Bech-Otschir, D., M. Seeger, and W. Dubiel. 2002. The COP9 signalosome: at the interface between signal transduction and ubiquitin-dependent proteolysis. J. Cell Sci. 115:467-473.
-
(2002)
J. Cell Sci.
, vol.115
, pp. 467-473
-
-
Bech-Otschir, D.1
Seeger, M.2
Dubiel, W.3
-
5
-
-
0034611731
-
Integrin LFA-1 interacts with the transcriptional coactivator JAB1 to modulate AP-1 activity
-
Bianchi, E., S. Denti, A. Granata, G. Bossi, J. Geginat, A. Villa, L. Rogge, and R. Pardi. 2000. Integrin LFA-1 interacts with the transcriptional coactivator JAB1 to modulate AP-1 activity. Nature 404:617-621.
-
(2000)
Nature
, vol.404
, pp. 617-621
-
-
Bianchi, E.1
Denti, S.2
Granata, A.3
Bossi, G.4
Geginat, J.5
Villa, A.6
Rogge, L.7
Pardi, R.8
-
6
-
-
0034650266
-
A mechanism of suppression of TGF-β/SMAD signaling by NFκB/RelA
-
Bitzer, M., G. von Gersdorff, D. Liang, A. Dominguez-Rosales, A. A. Beg, M. Rojkind, and E. P. Böttinger. 2000. A mechanism of suppression of TGF-β/SMAD signaling by NFκB/RelA. Genes Dev. 14:187-197.
-
(2000)
Genes Dev.
, vol.14
, pp. 187-197
-
-
Bitzer, M.1
Von Gersdorff, G.2
Liang, D.3
Dominguez-Rosales, A.4
Beg, A.A.5
Rojkind, M.6
Böttinger, E.P.7
-
7
-
-
0032441479
-
Ubiquitin and the control of protein fate in the secretory and endocytic pathways
-
Bonifacino, J. S., and A. M. Weissman. 1998. Ubiquitin and the control of protein fate in the secretory and endocytic pathways. Annu. Rev. Cell Biol. 14:19-57.
-
(1998)
Annu. Rev. Cell Biol.
, vol.14
, pp. 19-57
-
-
Bonifacino, J.S.1
Weissman, A.M.2
-
8
-
-
0032101098
-
Xenopus Smad7 inhibits both the activin and BMP pathways and acts as a neural inducer
-
Casellas, R., and A. H. Brivanlou. 1998. Xenopus Smad7 inhibits both the activin and BMP pathways and acts as a neural inducer. Dev. Biol. 198:1-12.
-
(1998)
Dev. Biol.
, vol.198
, pp. 1-12
-
-
Casellas, R.1
Brivanlou, A.H.2
-
9
-
-
0034708820
-
JAB1 interacts with both the progesterone receptor and SRC-1
-
Chauchereau, A., M. Georgiakaki, M. Perrin-Wolff, E. Milgrom, and H. Loosfelt. 2000. JAB1 interacts with both the progesterone receptor and SRC-1. J. Biol. Chem. 275:8540-8548.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 8540-8548
-
-
Chauchereau, A.1
Georgiakaki, M.2
Perrin-Wolff, M.3
Milgrom, E.4
Loosfelt, H.5
-
10
-
-
0029099161
-
The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules
-
Chen, H. I., and M. Sudol. 1995. The WW domain of Yes-associated protein binds a proline-rich ligand that differs from the consensus established for Src homology 3-binding modules. Proc. Natl. Acad. Sci. USA 92:7819-7823.
-
(1995)
Proc. Natl. Acad. Sci. USA
, vol.92
, pp. 7819-7823
-
-
Chen, H.I.1
Sudol, M.2
-
11
-
-
0029761277
-
A new group of conserved coactivators that increase the specificity of AP-1 transcription factors
-
Claret, F. X., M. Hibi, S. Dhut, T. Toda, and M. Karin. 1996. A new group of conserved coactivators that increase the specificity of AP-1 transcription factors. Nature 383:453-457.
-
(1996)
Nature
, vol.383
, pp. 453-457
-
-
Claret, F.X.1
Hibi, M.2
Dhut, S.3
Toda, T.4
Karin, M.5
-
12
-
-
0033519690
-
The Bcl-3 oncoprotein acts as a bridging factor between NF-κB/Rel and nuclear co-regulators
-
Dechend, R., F. Hirano, K. Lehman, V. Heissmeyer, S. Ansieau, F. G. Wulczyn, C. Scheidereit, and A. Leutz. 1999. The Bcl-3 oncoprotein acts as a bridging factor between NF-κB/Rel and nuclear co-regulators. Oncogene 18:3316-3323.
-
(1999)
Oncogene
, vol.18
, pp. 3316-3323
-
-
Dechend, R.1
Hirano, F.2
Lehman, K.3
Heissmeyer, V.4
Ansieau, S.5
Wulczyn, F.G.6
Scheidereit, C.7
Leutz, A.8
-
13
-
-
0034192005
-
Unified nomenclature for the COP9 signalosome and its subunits: An essential regulator of development
-
Deng, X. W., W. Dubiel, N. Wei, K. Hofmann, and K. Mundt. 2000. Unified nomenclature for the COP9 signalosome and its subunits: an essential regulator of development. Trends Genet. 16:202-203.
-
(2000)
Trends Genet.
, vol.16
, pp. 202-203
-
-
Deng, X.W.1
Dubiel, W.2
Wei, N.3
Hofmann, K.4
Mundt, K.5
-
14
-
-
0032442852
-
Smads: Transcriptional activators of TGF-β responses
-
Derynck, R., Y. Zhang, and X.-H. Feng. 1998. Smads: transcriptional activators of TGF-β responses. Cell 95:737-740.
-
(1998)
Cell
, vol.95
, pp. 737-740
-
-
Derynck, R.1
Zhang, Y.2
Feng, X.-H.3
-
15
-
-
0033279836
-
SCF and Cullin/Ring H2-based ubiquitin ligases
-
Deshaies, R. J. 1999. SCF and Cullin/Ring H2-based ubiquitin ligases. Annu. Rev. Cell Dev. Biol. 15:435-467.
-
(1999)
Annu. Rev. Cell Dev. Biol.
, vol.15
, pp. 435-467
-
-
Deshaies, R.J.1
-
16
-
-
0035918274
-
Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation
-
Ebisawa, T., M. Fukuchi, G. Murakami, T. Chiba, K. Tanaka, T. Imamura, and K. Miyazono. 2001. Smurf1 interacts with transforming growth factor-β type I receptor through Smad7 and induces receptor degradation. J. Biol. Chem. 276:12477-12480.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 12477-12480
-
-
Ebisawa, T.1
Fukuchi, M.2
Murakami, G.3
Chiba, T.4
Tanaka, K.5
Imamura, T.6
Miyazono, K.7
-
17
-
-
16044369574
-
MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma
-
Eppert, K., S. W. Scherer, H. Ozcelik, R. Pirone, P. Hoodless, H. Kim, L. C. Tsui, B. Bapat, S. Gallinger, I. L. Andrulis, G. H. Thomsen, J. L. Wrana, and L. Attisano. 1996. MADR2 maps to 18q21 and encodes a TGFβ-regulated MAD-related protein that is functionally mutated in colorectal carcinoma. Cell 86:543-552.
-
(1996)
Cell
, vol.86
, pp. 543-552
-
-
Eppert, K.1
Scherer, S.W.2
Ozcelik, H.3
Pirone, R.4
Hoodless, P.5
Kim, H.6
Tsui, L.C.7
Bapat, B.8
Gallinger, S.9
Andrulis, I.L.10
Thomsen, G.H.11
Wrana, J.L.12
Attisano, L.13
-
18
-
-
0032718990
-
Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation
-
Fujii, M., K. T. Takeda, H. Imamura, T. K. Aoki, S. Sampath, M. Enomoto, M. Kawabata, H. Kato, H. Ichijo, and K. Miyazono. 1999. Roles of bone morphogenetic protein type I receptors and Smad proteins in osteoblast and chondroblast differentiation. Mol. Biol. Cell 10:3801-3813.
-
(1999)
Mol. Biol. Cell
, vol.10
, pp. 3801-3813
-
-
Fujii, M.1
Takeda, K.T.2
Imamura, H.3
Aoki, T.K.4
Sampath, S.5
Enomoto, M.6
Kawabata, M.7
Kato, H.8
Ichijo, H.9
Miyazono, K.10
-
19
-
-
0032483546
-
A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3
-
Glickman, M. H., D. M. Rubin, O. Coux, I. Wefes, G. Pfeifer, Z. Cjeka, W. Baumeister, V. A. Fried, and D. Finley. 1998. A subcomplex of the proteasome regulatory particle required for ubiquitin-conjugate degradation and related to the COP9-signalosome and eIF3. Cell 94:615-623.
-
(1998)
Cell
, vol.94
, pp. 615-623
-
-
Glickman, M.H.1
Rubin, D.M.2
Coux, O.3
Wefes, I.4
Pfeifer, G.5
Cjeka, Z.6
Baumeister, W.7
Fried, V.A.8
Finley, D.9
-
20
-
-
0030593038
-
DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1
-
Hahn, S. A., M. Schutte, A. T. Hoque, C. A. Moskaluk, L. T. da Costa, E. Rozenblum, C. L. Weinstein, A. Fischer, C. J. Yeo, R. H. Hruban, and S. E. Kern. 1996. DPC4, a candidate tumor suppressor gene at human chromosome 18q21.1. Science 271:350-353.
-
(1996)
Science
, vol.271
, pp. 350-353
-
-
Hahn, S.A.1
Schutte, M.2
Hoque, A.T.3
Moskaluk, C.A.4
Da Costa, L.T.5
Rozenblum, E.6
Weinstein, C.L.7
Fischer, A.8
Yeo, C.J.9
Hruban, R.H.10
Kern, S.E.11
-
21
-
-
0031587828
-
The MAD-related protein Smad7 associates with the TGF-β receptor and functions as an antagonist of TGF-β signaling
-
Hayashi, H., S. Abdollah, Y. Qiu, J. Cai, Y.-Y. Xu, B. W. Grinnell, M. A. Richardson, J. N. Topper, M. A. Gimbrone, Jr., J. L. Wrana, and D. Falb. 1997. The MAD-related protein Smad7 associates with the TGF-β receptor and functions as an antagonist of TGF-β signaling. Cell 89:1165-1173.
-
(1997)
Cell
, vol.89
, pp. 1165-1173
-
-
Hayashi, H.1
Abdollah, S.2
Qiu, Y.3
Cai, J.4
Xu, Y.-Y.5
Grinnell, B.W.6
Richardson, M.A.7
Topper, J.N.8
Gimbrone Jr., M.A.9
Wrana, J.L.10
Falb, D.11
-
22
-
-
0031438047
-
TGF-β signalling from cell membrane to nucleus through SMAD proteins
-
Heldin, C.-H., K. Miyazono, and P. ten Dijke. 1997. TGF-β signalling from cell membrane to nucleus through SMAD proteins. Nature 390:465-471.
-
(1997)
Nature
, vol.390
, pp. 465-471
-
-
Heldin, C.-H.1
Miyazono, K.2
Ten Dijke, P.3
-
24
-
-
0030765945
-
Smad6 inhibits signaling by the TGF-β superfamily
-
Imamura, T., M. Takase, A. Nishihara, E. Oeda, J.-I. Hanai, M. Kawabata, and K. Miyazono. 1997. Smad6 inhibits signaling by the TGF-β superfamily. Nature 389:622-626.
-
(1997)
Nature
, vol.389
, pp. 622-626
-
-
Imamura, T.1
Takase, M.2
Nishihara, A.3
Oeda, E.4
Hanai, J.-I.5
Kawabata, M.6
Miyazono, K.7
-
25
-
-
0032582672
-
Transforming growth factor β1 induces nuclear export of inhibitory Smad7
-
Itoh, S., M. Landstrom, A. Hermansson, F. Itoh, C.-H. Heldin, N.-E. Heldin, and P. ten Dijke. 1998. Transforming growth factor β1 induces nuclear export of inhibitory Smad7. J. Biol. Chem. 273:29195-29201.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 29195-29201
-
-
Itoh, S.1
Landstrom, M.2
Hermansson, A.3
Itoh, F.4
Heldin, C.-H.5
Heldin, N.-E.6
Ten Dijke, P.7
-
26
-
-
0034517389
-
Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF-β receptor for degradation
-
Kavsak, P., R. K. Rasmussen, C. G. Caysing, S. Bonni, H. Zhu, G. H. Thomsen, and J. L. Wrana. 2000. Smad7 binds to Smurf2 to form an E3 ubiquitin ligase that targets the TGF-β receptor for degradation. Mol. Cell 6:1365-1375.
-
(2000)
Mol. Cell
, vol.6
, pp. 1365-1375
-
-
Kavsak, P.1
Rasmussen, R.K.2
Caysing, C.G.3
Bonni, S.4
Zhu, H.5
Thomsen, G.H.6
Wrana, J.L.7
-
27
-
-
0034027480
-
Molecular mechanisms of inactivation of TGF-β receptors during carcinogenesis
-
Kim, S.-J., Y.-H. Im, S. D. Markowitz, and Y.-J. Bang. 2000. Molecular mechanisms of inactivation of TGF-β receptors during carcinogenesis. Cytokine Growth Factor Rev. 11:159-168.
-
(2000)
Cytokine Growth Factor Rev.
, vol.11
, pp. 159-168
-
-
Kim, S.-J.1
Im, Y.-H.2
Markowitz, S.D.3
Bang, Y.-J.4
-
28
-
-
0033598408
-
The TGF-β signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer
-
Kleeff, J., T. Ishiwata, H. Maruyama, H. Friess, P. Truong, M. W. Buchler, D. Falb, and M. Korc. 1999. The TGF-β signaling inhibitor Smad7 enhances tumorigenicity in pancreatic cancer. Oncogene 18:5363-5372.
-
(1999)
Oncogene
, vol.18
, pp. 5363-5372
-
-
Kleeff, J.1
Ishiwata, T.2
Maruyama, H.3
Friess, H.4
Truong, P.5
Buchler, M.W.6
Falb, D.7
Korc, M.8
-
29
-
-
0034626730
-
Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1
-
Kleemann, R., A. Hausser, G. Geiger, R. Mischke, A. Burger-Kentischer, O. Flieger, F. J. Johannes, T. Roger, T. Calandra, A. Kapurniotu, M. Grell, D. Finkelmeier, H. Brunner, and J. Bernhagen. 2000. Intracellular action of the cytokine MIF to modulate AP-1 activity and the cell cycle through Jab1. Nature 408:211-216.
-
(2000)
Nature
, vol.408
, pp. 211-216
-
-
Kleemann, R.1
Hausser, A.2
Geiger, G.3
Mischke, R.4
Burger-Kentischer, A.5
Flieger, O.6
Johannes, F.J.7
Roger, T.8
Calandra, T.9
Kapurniotu, A.10
Grell, M.11
Finkelmeier, D.12
Brunner, H.13
Bernhagen, J.14
-
30
-
-
0032203713
-
Arabidopsis homologs of a c-Jun coactivator are present both in monomeric form and in the COP9 complex and their abundance is differentially affected by the pleiotropic cop/det/fus mutations
-
Kwok, S. F., R. Solano, T. Tsuge, D. A. Chamovitz, J. R. Ecker, M. Matsui, and X. W. Deng. 1998. Arabidopsis homologs of a c-Jun coactivator are present both in monomeric form and in the COP9 complex and their abundance is differentially affected by the pleiotropic cop/det/fus mutations. Plant Cell 10:1779-1790.
-
(1998)
Plant Cell
, vol.10
, pp. 1779-1790
-
-
Kwok, S.F.1
Solano, R.2
Tsuge, T.3
Chamovitz, D.A.4
Ecker, J.R.5
Matsui, M.6
Deng, X.W.7
-
31
-
-
0035864759
-
Smad7 inhibits the survival nuclear factor κB and potentiates apoptosis in epithelial cells
-
Lallemand, F., A. Mazars, C. Prunier, F. Bertrand, M. Kornprost, S. Gallea, S. Roman-Roman, G. Cherqui, and A. Atfi. 2001. Smad7 inhibits the survival nuclear factor κB and potentiates apoptosis in epithelial cells. Oncogene 20:879-884.
-
(2001)
Oncogene
, vol.20
, pp. 879-884
-
-
Lallemand, F.1
Mazars, A.2
Prunier, C.3
Bertrand, F.4
Kornprost, M.5
Gallea, S.6
Roman-Roman, S.7
Cherqui, G.8
Atfi, A.9
-
32
-
-
0034193758
-
Smad7 mediates apoptosis induced by transforming growth factor β in prostatic carcinoma cells
-
Landstrom, M., N. E. Heldin, S. Bu, A. Hermansson, S. Itoh, P. ten Dijke, and C. H. Heldin. 2000. Smad7 mediates apoptosis induced by transforming growth factor β in prostatic carcinoma cells. Curr. Biol. 10:535-538.
-
(2000)
Curr. Biol.
, vol.10
, pp. 535-538
-
-
Landstrom, M.1
Heldin, N.E.2
Bu, S.3
Hermansson, A.4
Itoh, S.5
Ten Dijke, P.6
Heldin, C.H.7
-
33
-
-
0034711290
-
Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-β signaling
-
Lin, X., M. Liang, and X.-H. Feng. 2000. Smurf2 is a ubiquitin E3 ligase mediating proteasome-dependent degradation of Smad2 in transforming growth factor-β signaling. J. Biol. Chem. 275:36818-36822.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36818-36822
-
-
Lin, X.1
Liang, M.2
Feng, X.-H.3
-
34
-
-
0030183051
-
Tumor suppressor activity of the TGF-β pathway in human cancers
-
Markowitz, S. D., and A. B. Roberts. 1996. Tumor suppressor activity of the TGF-β pathway in human cancers. Cytokine Growth Factor Rev. 7:93-102.
-
(1996)
Cytokine Growth Factor Rev.
, vol.7
, pp. 93-102
-
-
Markowitz, S.D.1
Roberts, A.B.2
-
35
-
-
0034654497
-
Controlling TGF-β signaling
-
Massagué, J., and Y. G. Chen. 2000. Controlling TGF-β signaling. Genes Dev. 14:627-644.
-
(2000)
Genes Dev.
, vol.14
, pp. 627-644
-
-
Massagué, J.1
Chen, Y.G.2
-
36
-
-
0034678908
-
Transcriptional control by the TGF-β/Smad signaling system
-
Massagué, J., and D. Wotton. 2000. Transcriptional control by the TGF-β/Smad signaling system. EMBO J. 19:1745-1754.
-
(2000)
EMBO J.
, vol.19
, pp. 1745-1754
-
-
Massagué, J.1
Wotton, D.2
-
37
-
-
0036788304
-
Gene silencing in mammals by small interfering RNAs
-
McManus, M. T., and P. A. Sharp. 2002. Gene silencing in mammals by small interfering RNAs. Nat. Rev. Genet. 3:737-747.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 737-747
-
-
McManus, M.T.1
Sharp, P.A.2
-
38
-
-
0034016101
-
Positive and negative regulation of TGF-β signaling
-
Miyazono, K. 2000. Positive and negative regulation of TGF-β signaling. J. Cell Sci. 113:1101-1109.
-
(2000)
J. Cell Sci.
, vol.113
, pp. 1101-1109
-
-
Miyazono, K.1
-
39
-
-
0024991898
-
pEF-BOS, a powerful mammalian expression vector
-
Mizushima, S., and S. Nagata. 1990. pEF-BOS, a powerful mammalian expression vector. Nucleic Acids Res. 18:5322.
-
(1990)
Nucleic Acids Res.
, vol.18
, pp. 5322
-
-
Mizushima, S.1
Nagata, S.2
-
40
-
-
0030611757
-
Identification of Smad7, a TGF-β-inducible antagonist of TGF-β signalling
-
Nakao, A., M. Afrakhte, A. Moren, T. Nakayama, J. L. Christian, R. Heuchel, S. Itoh, M. Kawabata, N.-E. Heldin, C.-H. Heldin, and P. ten Dijke. 1997. Identification of Smad7, a TGF-β-inducible antagonist of TGF-β signalling. Nature 389:631-635.
-
(1997)
Nature
, vol.389
, pp. 631-635
-
-
Nakao, A.1
Afrakhte, M.2
Moren, A.3
Nakayama, T.4
Christian, J.L.5
Heuchel, R.6
Itoh, S.7
Kawabata, M.8
Heldin, N.-E.9
Heldin, C.-H.10
Ten Dijke, P.11
-
41
-
-
0036380988
-
Smad7 mediates transforming growth factor-β-induced apoptosis in mesangial cells
-
Okado, T., Y. Terada, H. Tanaka, S. Inoshita, A. Nakao, and S. Sasaki. 2002. Smad7 mediates transforming growth factor-β-induced apoptosis in mesangial cells. Kidney Int. 62:1178-1186.
-
(2002)
Kidney Int.
, vol.62
, pp. 1178-1186
-
-
Okado, T.1
Terada, Y.2
Tanaka, H.3
Inoshita, S.4
Nakao, A.5
Sasaki, S.6
-
42
-
-
0034713297
-
Targeted destabilization of HY5 during light-regulated development of Arabidopsis
-
Osterlund, M. T., C. S. Hardtke, N. Wei, and X. W. Deng. 2000. Targeted destabilization of HY5 during light-regulated development of Arabidopsis. Nature 405:462-466.
-
(2000)
Nature
, vol.405
, pp. 462-466
-
-
Osterlund, M.T.1
Hardtke, C.S.2
Wei, N.3
Deng, X.W.4
-
43
-
-
0035958052
-
Phosphorylation of Smad7 at Ser-249 does not interfere with its inhibitory role in transforming growth factor-β-dependent signaling but affects Smad7-dependent transcriptional activation
-
Pulaski, L., M. Landstrom, C. H. Heldin, and S. Souchelnytskyi. 2001. Phosphorylation of Smad7 at Ser-249 does not interfere with its inhibitory role in transforming growth factor-β-dependent signaling but affects Smad7-dependent transcriptional activation. J. Biol. Chem. 276:14344-14349.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 14344-14349
-
-
Pulaski, L.1
Landstrom, M.2
Heldin, C.H.3
Souchelnytskyi, S.4
-
44
-
-
0000116653
-
The transforming growth factor-βs
-
M. B. Sporn and A. B. Roberts (ed.). Springer-Verlag, Heidelberg, Germany
-
Roberts, A. B., and M. B. Sporn. 1990. The transforming growth factor-βs, 419-472. In M. B. Sporn and A. B. Roberts (ed.), Peptide growth factors and their receptors, part I. Springer-Verlag, Heidelberg, Germany.
-
(1990)
Peptide Growth Factors and Their Receptors, Part I
, pp. 419-472
-
-
Roberts, A.B.1
Sporn, M.B.2
-
45
-
-
0034491482
-
The COP/DET/FUS proteins-regulators of eukaryotic growth and development
-
Schwechheimer, C., and X. W. Deng. 2000. The COP/DET/FUS proteins-regulators of eukaryotic growth and development. Semin. Cell Dev. Biol. 11:495-503.
-
(2000)
Semin. Cell Dev. Biol.
, vol.11
, pp. 495-503
-
-
Schwechheimer, C.1
Deng, X.W.2
-
46
-
-
0032566611
-
Physical and functional interaction of murine and Xenopus Smad7 with bone morphogenetic protein receptors and transforming growth factor-β receptors
-
Souchelnytskyi, S., T. Nakayama, A. Nakao, A. Morén, C.-H. Heldin, J. L. Christian, and P. ten Dijke. 1998. Physical and functional interaction of murine and Xenopus Smad7 with bone morphogenetic protein receptors and transforming growth factor-β receptors. J. Biol. Chem. 273:25364-25370.
-
(1998)
J. Biol. Chem.
, vol.273
, pp. 25364-25370
-
-
Souchelnytskyi, S.1
Nakayama, T.2
Nakao, A.3
Morén, A.4
Heldin, C.-H.5
Christian, J.L.6
Ten Dijke, P.7
-
47
-
-
0037131283
-
Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane
-
Suzuki, C., G. Murakami, M. Fukuchi, T. Shimanuki, Y. Shikauchi, T. Imamura, and K. Miyazono. 2002. Smurf1 regulates the inhibitory activity of Smad7 by targeting Smad7 to the plasma membrane. J. Biol. Chem. 277:39919-39925.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 39919-39925
-
-
Suzuki, C.1
Murakami, G.2
Fukuchi, M.3
Shimanuki, T.4
Shikauchi, Y.5
Imamura, T.6
Miyazono, K.7
-
48
-
-
0038363366
-
Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-β signaling by Smad7
-
Tajima, Y., K. Goto, M. Yoshida, K. Shinomiya, T. Sekimoto, Y. Yoneda, and K. Miyazono. 2003. Chromosomal region maintenance 1 (CRM1)-dependent nuclear export of Smad ubiquitin regulatory factor 1 (Smurf1) is essential for negative regulation of transforming growth factor-β signaling by Smad7. J. Biol. Chem. 278:10716-10721.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 10716-10721
-
-
Tajima, Y.1
Goto, K.2
Yoshida, M.3
Shinomiya, K.4
Sekimoto, T.5
Yoneda, Y.6
Miyazono, K.7
-
50
-
-
0037127256
-
Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex
-
Kip1 mediated by Jab1/CSN5 and the COP9 signalosome complex. J. Biol. Chem. 277:2302-2310.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 2302-2310
-
-
Tomoda, K.1
Kubota, Y.2
Arata, Y.3
Mori, S.4
Maeda, M.5
Tanaka, T.6
Yoshida, M.7
Yoneda-Kato, N.8
Kato, J.-J.9
-
51
-
-
0033602101
-
Inhibition of transforming growth factor-β/SMAD signalling by the interferon-γ/STAT pathway
-
Ulloa, L., J. Doody, and J. Massagué. 1999. Inhibition of transforming growth factor-β/SMAD signalling by the interferon-γ/ STAT pathway. Nature 397:710-713.
-
(1999)
Nature
, vol.397
, pp. 710-713
-
-
Ulloa, L.1
Doody, J.2
Massagué, J.3
-
52
-
-
0036198412
-
Jab1 antagonizes TGF-β signaling by inducing Smad4 degradation
-
Wan, M., X. Cao, S. Bai, L. Wu, X. Shi, N. Wang, and X. Cao. 2002. Jab1 antagonizes TGF-β signaling by inducing Smad4 degradation. EMBO Rep. 3:171-176.
-
(2002)
EMBO Rep.
, vol.3
, pp. 171-176
-
-
Wan, M.1
Cao, X.2
Bai, S.3
Wu, L.4
Shi, X.5
Wang, N.6
Cao, X.7
-
53
-
-
0032993486
-
Making sense of the COP9 signalosome. A regulatory protein complex conserved from Arabidopsis to human
-
Wei, N., and X. W. Deng. 1999. Making sense of the COP9 signalosome. A regulatory protein complex conserved from Arabidopsis to human. Trends Genet. 15:98-103.
-
(1999)
Trends Genet.
, vol.15
, pp. 98-103
-
-
Wei, N.1
Deng, X.W.2
-
54
-
-
0026496172
-
TGF-β signals through a heteromeric protein kinase receptor complex
-
Wrana, J. L., L. Attisano, J. Carcamo, A. Zentella, J. Doody, M. Laiho, X.-F. Wang, and J. Massagué. 1992. TGF-β signals through a heteromeric protein kinase receptor complex. Cell 71:1003-1014.
-
(1992)
Cell
, vol.71
, pp. 1003-1014
-
-
Wrana, J.L.1
Attisano, L.2
Carcamo, J.3
Zentella, A.4
Doody, J.5
Laiho, M.6
Wang, X.-F.7
Massagué, J.8
-
55
-
-
0034680863
-
Critical role of Smads and AP-1 complex in transforming growth factor-β-dependent apoptosis
-
Yamamura, Y., X. Hua, S. Bergelson, and H. F. Lodish. 2000. Critical role of Smads and AP-1 complex in transforming growth factor-β-dependent apoptosis. J. Biol. Chem. 275:36295-36302.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 36295-36302
-
-
Yamamura, Y.1
Hua, X.2
Bergelson, S.3
Lodish, H.F.4
-
56
-
-
0034637527
-
Oncogenic signals of HER-2/neu in regulating the stability of the cyclin-dependent kinase inhibitor p27
-
Yang, H.-Y., B. P. Zhou, M.-C. Hung, and M.-H. Lee. 2000. Oncogenic signals of HER-2/neu in regulating the stability of the cyclin-dependent kinase inhibitor p27. J. Biol. Chem. 275:24735-24739.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 24735-24739
-
-
Yang, H.-Y.1
Zhou, B.P.2
Hung, M.-C.3
Lee, M.-H.4
-
57
-
-
0032014216
-
Human Smad3 and Smad4 are sequence-specific transcription activators
-
Zawel, L., J. L. Dai, P. Buckhaults, S. Zhou, K. W. Kinzler, B. Vogelstein, and S. E. Kern. 1998. Human Smad3 and Smad4 are sequence-specific transcription activators. Mol. Cell 1:611-617.
-
(1998)
Mol. Cell
, vol.1
, pp. 611-617
-
-
Zawel, L.1
Dai, J.L.2
Buckhaults, P.3
Zhou, S.4
Kinzler, K.W.5
Vogelstein, B.6
Kern, S.E.7
-
58
-
-
0033549789
-
ASMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation
-
Zhu, H., P. Kavsak, S. Abdollah, J. L. Wrana, and G. H. Thomsen. 1999. ASMAD ubiquitin ligase targets the BMP pathway and affects embryonic pattern formation. Nature 400:687-693.
-
(1999)
Nature
, vol.400
, pp. 687-693
-
-
Zhu, H.1
Kavsak, P.2
Abdollah, S.3
Wrana, J.L.4
Thomsen, G.H.5
-
59
-
-
0033527741
-
Smad7 differentially regulates transforming growth factor β-signaling pathways
-
Zhu, H.-J., J. Iaria, and A. M. Sizeland. 1999. Smad7 differentially regulates transforming growth factor β-signaling pathways. J. Biol. Chem. 274:32258-32264.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 32258-32264
-
-
Zhu, H.-J.1
Iaria, J.2
Sizeland, A.M.3
|