Mtd, a novel Bcl-2 family member activates apoptosis in the absence of heterodimerization with Bcl-2 and Bcl-X(L)

Journal of Biological Chemistry

Volumn 273, Issue 15, 1998, Pages 8705-8710

  Inohara, Naohiro ^a   Ekhterae, Daryoush ^a   Garcia, Irene ^b   Carrio, Roberto ^c   Merino, Jesus ^c   Merry, Andrew ^a   Chen, Shu ^a   Núñez, Gabriel ^a,d  

^a UNIVERSITY OF MICHIGAN MEDICAL SCHOOL   (United States)

^b UNIVERSITY OF GENEVA MEDICAL SCHOOL   (Switzerland)

^c UNIVERSITY OF CANTABRIA   (Spain)

^d NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENTARY DNA; COMPLEMENTARY RNA; MESSENGER RNA; PROTEIN BCL 2;

AMINO ACID SEQUENCE; ANIMAL CELL; APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; EMBRYO; IN SITU HYBRIDIZATION; MOLECULAR CLONING; MOUSE; NONHUMAN; NORTHERN BLOTTING; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL;

AMINO ACID SEQUENCE; ANIMALS; APOPTOSIS; BASE SEQUENCE; BCL-X PROTEIN; CELL LINE; CELL SURVIVAL; CONSERVED SEQUENCE; DIMERIZATION; EMBRYO; GENE EXPRESSION REGULATION, DEVELOPMENTAL; HELA CELLS; HUMANS; MOLECULAR SEQUENCE DATA; NEURONS, AFFERENT; ORGAN SPECIFICITY; PROTO-ONCOGENE PROTEINS C-BCL-2; RATS; RECOMBINANT PROTEINS; RNA, MESSENGER; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY, AMINO ACID; SUPERIOR CERVICAL GANGLION; TRANSCRIPTION, GENETIC;

ANIMALIA;

EID: 0032502776     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.273.15.8705     Document Type: Article

References (42)

1. Thompson, C. B. (1995) Science 267, 1456-1462
2. White, E. (1996) Genes Dev. 10, 1-15
3. Vaux, D. L., Cory, S., and Adams, J. M. (1988) Nature 335, 440-442
4. Núñez, G., London, L., Hockenbery, D., Alexander, M., McKearn, J. P., and Korsmeyer, S. J. (1990) J. Immunol. 144, 3602-3610
5. Strasser, A., Harris, A. W., and Cory, S. (1991) Cell 67, 889-899
6. Oltvai, Z. N., Milliman, C. L., and Korsmeyer, S. J. (1993) Cell 74, 609-619
7. Zha, H., Aime-Sempe, C., Sato, T., and Reed, J. C. (1996) J. Biol. Chem. 271, 7440-7444
8. Muchmore, S. W., Sattler, M., Liang, H., Meadows, R. P., Harlan, J. E., Yoon, H. S., Nettesheim, D., Chang, B. S., Thompson, C. B., Wong, S. L., Ng, S. L., and Fesik, S. W. (1996) Nature 381, 335-341
9. Aritomi, M., Kunisima, N., Inohara, N., Ishibashi, Y., Ohta, S., and Morikawa, K. (1997) J. Biol. Chem. 272, 27886-27892
10. Minn, A. J., Velez, P., Schendel, S. L., Liang, H., Muchmore, S. W., Fesik, S. W., Fill, M., and Thompson, C. B. (1997) Nature 385, 353-357
11. Schendel, S. L., Xie, Z., Montal, M. O., Matsuyama, S., Montal, M., and Reed, J. C. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 5113-5118
12. Antonsson, B., Conti, F., Ciavatta, A., Montessuit, S., Lewis, S., Martinou, I., Bernasconi, L., Bernard, A., Mermod, J. J., Mazzei, G., Maundrell, K., Gambale, F., Sadoul, R., and Martinou, J. C. (1997) Science 277, 370-372
13. Chinnaiyan, A. M., O'Rourke, K., Lane, B. R., and Dixit, V. M. (1997) Science 275, 1122-1126
14. Wu, D., Wallen, H. D., and Núñez, G. (1997) Science 275, 1126-1129
15. Wu, D., Wallen, H. D., Inohara, N., and Nunez, G. (1997) J. Biol. Chem. 272, 21449-21454
16. Oltvai, Z. N., Milliman, C. L., and Korsmeyer, S. J. (1993) Cell 74, 609-619
17. Farrow, S. N., White, J. H., Martinou, I., Raven, T., Pun, K. T., Grinham, C. J., Martinou, J. C., and Brown, R. (1995) Nature 374, 731-733
18. Chittenden, T., Harrington, E. A., O'Connor, R., Flemington, C., Lutz, R. J., Evan, G. I., and Guild, B. C. (1995) Nature 374, 733-736
19. Yang, E., Zha, J., Jockel, J., Boise, L. H., Thompson, C. B., and Korsmeyer, S. J. (1995) Cell 80, 285-291
20. Wang, K., Yin, X. M., Chao, D. T., Milliman, C. L., and Korsmeyer, S. J. (1996) Genes Dev. 10, 2859-2869
21. Boyd, J. M., Gallo, G. J., Elangovan, B., Houghton, A. B., Malstrom, S., Avery, B. J., Ebb, R. G., Subramanian, T., Chittenden, T., and Lutz, R. J. (1995) Oncogene 11, 1921-1928
22. Han, J., Sabbatini, P., and White, E. (1996) Mol. Cell. Biol. 16, 5857-5864
23. Inohara, N., Ding, L., Chen, S., and Nunez, G. (1997) EMBO J. 16, 1686-1694
24. Chittenden, T., Flemington, C., Houghton, A. B., Ebb, R. G., Gallo, G. J., Elangovan, B., Chinnadurai, G., and Lutz, R. J. (1995) EMBO J. 14, 5589-5596
25. Han, J., Sabbatini, P., Perez, D., Rao, L., Modha, D., and White, E. (1996) Genes Dev. 10, 461-477
26. Sattler, M., Liang, H., Nettesheim, D., Meadows, R. P., Harlan, J. E., Eberstadt, M., Yoon, H. S., Shuker, S. B., Chang, B. S., Minn, A. J., Thompson, C. B., and Fesik, S. W. (1997) Science 275, 983-986
27. Yin, X. M., Oltvai, Z. N., and Korsmeyer, S. J. (1994) Nature 369, 321-323
28. Cheng, E. H., Levine, B., Boise, L. H., Thompson, C. B., and Hardwick, J. M. (1996) Nature 379, 554-556
29. Sedlak, T. W., Oltvai, Z. N., Yang, E., Wang, K., Boise, L. H., Thompson, C. B., and Korsmeyer, S. J. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 7834-7838
30. Simonian, P. L., Grillot, D. A. M., Merino, R., and Nunez, G. (1996) J. Biol. Chem. 271, 22764-22772
31. Simonian, P. L., Grillot, D. A. M., and Nunez, G. (1997) Oncogene 15, 1871-1875
32. Gonzalez-Garcia, M., Perez-Ballestero, R., Ding, L., Duan, L., Boise, L. H., Thompson, C. B., and Nunez, G. (1994) Development (Camb.) 120, 3033-3042
33. Inohara, N., Koseki, T., Hu, Y., Chen, S., and Nunez, G. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 10717-10722
34. Gonzalez-Garcia, M., Garcia, I., Ding, L., O'Shea, S., Boise, L. H., Thompson, C. B., and Nunez, G. (1995) Proc. Natl. Acad. Sci. U. S. A. 92, 4304-4308
35. Herrmann, M., Lorenz, H. M., Voll, R., Grunke, M., Woith, W., and Kalden, J. R. (1994) Nucleic Acids Res. 22, 5506-5507
36. Carrio, R., Lopez-Hoyos, M., Jimeno, J., Benedict, M. A., Merino, R., Benito, A., Fernandez-Luna, J. L., Núñez, G., Garcia-Porrero, J. A., and Merino, J. (1996) Am. J. Pathol. 149, 2133-2142
37. Novak, D. V., and Korsmeyer, S. J. (1994) Am. J. Pathol. 145, 61-73
38. Yang, X., Khosravi-Far, R., Chang, H. Y., and Baltimore, D. (1997) Cell 89, 1067-1076
39. Xiang, J., Chao, D. T., and Korsmeyer, S. J. (1997) Proc. Natl. Acad. Sci. U. S. A. 93, 14559-14563
40. Reed, J. C. (1997) 387, 773-776
41. Kyte, J., and Doolittle, R. F. (1982) J. Mol. Biol. 157, 105-132
42. Hsu, S. Y., Kaipia, A., McGee, E., Lomeli, M., and Hsueh, A. J. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 12401-12406