-
1
-
-
10044241865
-
Functions of DNA polymerases
-
Bebenek,K. and Kunkel,T.A. (2004) Functions of DNA polymerases. Adv. Protein Chem., 69, 137-165.
-
(2004)
Adv. Protein Chem
, vol.69
, pp. 137-165
-
-
Bebenek, K.1
Kunkel, T.A.2
-
2
-
-
0035997349
-
Eukaryotic DNA polymerases
-
Hübscher,U., Maga,G. and Spadari,S. (2002) Eukaryotic DNA polymerases. Annu. Rev. Biochem., 71, 133-163.
-
(2002)
Annu. Rev. Biochem
, vol.71
, pp. 133-163
-
-
Hübscher, U.1
Maga, G.2
Spadari, S.3
-
3
-
-
2342419732
-
DNA replication fidelity
-
Kunkel,T.A. (2004) DNA replication fidelity. J. Biol. Chem., 279, 16895-16898.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 16895-16898
-
-
Kunkel, T.A.1
-
5
-
-
0035902108
-
Genome maintenance mechanisms for preventing cancer
-
Hoeijmakers,J.H. (2001) Genome maintenance mechanisms for preventing cancer. Nature, 411, 366-374.
-
(2001)
Nature
, vol.411
, pp. 366-374
-
-
Hoeijmakers, J.H.1
-
6
-
-
35348813734
-
Bacterial DNA repair genes and their eukaryotic homologues: 1. Mutations in genes involved in base excision repair (BER) and DNA-end processors and their implication in mutagenesis and human disease
-
Krwawicz,J., Arczewska,K.D., Speina,E., Maciejewska,A. and Grzesiuk,E. (2007) Bacterial DNA repair genes and their eukaryotic homologues: 1. Mutations in genes involved in base excision repair (BER) and DNA-end processors and their implication in mutagenesis and human disease. Acta Biochim. Pol., 54, 413-434.
-
(2007)
Acta Biochim. Pol
, vol.54
, pp. 413-434
-
-
Krwawicz, J.1
Arczewska, K.D.2
Speina, E.3
Maciejewska, A.4
Grzesiuk, E.5
-
7
-
-
0033520969
-
Quality control by DNA repair
-
Lindahl,T. and Wood,R.D. (1999) Quality control by DNA repair. Science, 286, 1897-1905.
-
(1999)
Science
, vol.286
, pp. 1897-1905
-
-
Lindahl, T.1
Wood, R.D.2
-
8
-
-
0032985826
-
DNA repair mechanisms for the recognition and removal of damaged DNA bases
-
Mol,C.D., Parikh,S.S., Putnam,C.D., Lo,T.P. and Tainer,J.A. (1999) DNA repair mechanisms for the recognition and removal of damaged DNA bases. Annu. Rev. Biophys. Biomol. Struct., 28, 101-128.
-
(1999)
Annu. Rev. Biophys. Biomol. Struct
, vol.28
, pp. 101-128
-
-
Mol, C.D.1
Parikh, S.S.2
Putnam, C.D.3
Lo, T.P.4
Tainer, J.A.5
-
9
-
-
0032822325
-
Envisioning the molecular choreography of DNA base excision repair
-
Parikh,S.S., Mol,C.D., Hosfield,D.J. and Tainer,J.A. (1999) Envisioning the molecular choreography of DNA base excision repair. Curr. Opin. Struct. Biol., 9, 37-47.
-
(1999)
Curr. Opin. Struct. Biol
, vol.9
, pp. 37-47
-
-
Parikh, S.S.1
Mol, C.D.2
Hosfield, D.J.3
Tainer, J.A.4
-
10
-
-
33747889722
-
Role of nonhomologous end joining (NHEJ) in maintaining genomic integrity
-
Burma,S., Chen,B.P. and Chen,D.J. (2006) Role of nonhomologous end joining (NHEJ) in maintaining genomic integrity. DNA Repair, 5 1042-1048.
-
(2006)
DNA Repair
, vol.5
, pp. 1042-1048
-
-
Burma, S.1
Chen, B.P.2
Chen, D.J.3
-
11
-
-
35848960148
-
Nonhomologous end-joining in bacteria: A microbial perspective
-
Pitcher,R.S., Brissett,N.C. and Doherty,A.J. (2007) Nonhomologous end-joining in bacteria: A microbial perspective. Annu. Rev. Microbiol., 61, 259-282.
-
(2007)
Annu. Rev. Microbiol
, vol.61
, pp. 259-282
-
-
Pitcher, R.S.1
Brissett, N.C.2
Doherty, A.J.3
-
12
-
-
35348890199
-
Bacterial DNA repair by non-homologous end joining
-
Shuman,S. and Glickman,M.S. (2007) Bacterial DNA repair by non-homologous end joining. Nat. Rev. Microbiol., 5, 852-861.
-
(2007)
Nat. Rev. Microbiol
, vol.5
, pp. 852-861
-
-
Shuman, S.1
Glickman, M.S.2
-
13
-
-
0037031655
-
-
Weller,G.R., Kysela,B., Roy.R., Tonkin,L.M., Scanian.E., Della,M., Devine,S.K., Day,J.P., Wilkinson,A., d'Adda di Fagagna,F. et al. (2002) Identification of a DNA nonhomologous end-joining complex in bacteria. Science, 297, 1686-1689.
-
Weller,G.R., Kysela,B., Roy.R., Tonkin,L.M., Scanian.E., Della,M., Devine,S.K., Day,J.P., Wilkinson,A., d'Adda di Fagagna,F. et al. (2002) Identification of a DNA nonhomologous end-joining complex in bacteria. Science, 297, 1686-1689.
-
-
-
-
14
-
-
23444444813
-
-
Braithwaite.E.K., Prasad,R., Shock.D.D., Hou,E.W., Beard,W.A. and Wilson,S.H. (2005) DNA polymerase lambda mediates a back-up base excision repair activity in extracts of mouse embryonic fibroblasts. J. Biol. Chem., 280, 18469-18475.
-
Braithwaite.E.K., Prasad,R., Shock.D.D., Hou,E.W., Beard,W.A. and Wilson,S.H. (2005) DNA polymerase lambda mediates a back-up base excision repair activity in extracts of mouse embryonic fibroblasts. J. Biol. Chem., 280, 18469-18475.
-
-
-
-
15
-
-
0035860767
-
Identification of an intrinsic 5′-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: A possible role in base excision repair
-
Garcia-Diaz,M., Bebenek,K., Kunkel,T.A. and Blanco,L. (2001) Identification of an intrinsic 5′-deoxyribose-5-phosphate lyase activity in human DNA polymerase lambda: A possible role in base excision repair. J. Biol. Chem., 276, 34659-34663.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 34659-34663
-
-
Garcia-Diaz, M.1
Bebenek, K.2
Kunkel, T.A.3
Blanco, L.4
-
16
-
-
0029028964
-
Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair
-
Matsumoto,Y. and Kim,K. (1995) Excision of deoxyribose phosphate residues by DNA polymerase beta during DNA repair. Science, 269 699-702.
-
(1995)
Science
, vol.269
, pp. 699-702
-
-
Matsumoto, Y.1
Kim, K.2
-
17
-
-
0032516831
-
Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps
-
Srivastava,D.K., Berg,B.J., Prasad,R., Molina,J.T., Beard,W.A., Tomkinson,A.E. and Wilson,S.H. (1998) Mammalian abasic site base excision repair. Identification of the reaction sequence and rate-determining steps. J. Biol. Chem., 273, 21203-21209.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 21203-21209
-
-
Srivastava, D.K.1
Berg, B.J.2
Prasad, R.3
Molina, J.T.4
Beard, W.A.5
Tomkinson, A.E.6
Wilson, S.H.7
-
18
-
-
4644328090
-
DNA polymerase lambda can elongate on DNA substrates mimicking non-homologous end joining and interact with XRCC4-ligase IV complex
-
Fan,W. and Wu,X. (2004) DNA polymerase lambda can elongate on DNA substrates mimicking non-homologous end joining and interact with XRCC4-ligase IV complex. Biochem. Biophys. Res. Commun., 323 1329-1333.
-
(2004)
Biochem. Biophys. Res. Commun
, vol.323
, pp. 1329-1333
-
-
Fan, W.1
Wu, X.2
-
19
-
-
4644364776
-
Involvement of an X family DNA polymerase in double-stranded break repair in the radioresistant organism Deinococcus radiodurans
-
Lecointe,F., Shevelev,I.V., Bailone,A., Sommer,S. and Hübscher,U. (2004) Involvement of an X family DNA polymerase in double-stranded break repair in the radioresistant organism Deinococcus radiodurans. Mol. Microbiol., 53, 1721-1730.
-
(2004)
Mol. Microbiol
, vol.53
, pp. 1721-1730
-
-
Lecointe, F.1
Shevelev, I.V.2
Bailone, A.3
Sommer, S.4
Hübscher, U.5
-
20
-
-
0347683431
-
-
Lee,J.W., Blanco.L., Zhou,T., Garcia-Diaz,M., Bebenek,K., Kunkel,T.A., Wang,Z. and Povirk,L.F. (2004) Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts. J. Biol. Chem., 279, 805-811.
-
Lee,J.W., Blanco.L., Zhou,T., Garcia-Diaz,M., Bebenek,K., Kunkel,T.A., Wang,Z. and Povirk,L.F. (2004) Implication of DNA polymerase lambda in alignment-based gap filling for nonhomologous DNA end joining in human nuclear extracts. J. Biol. Chem., 279, 805-811.
-
-
-
-
21
-
-
0036293744
-
-
Mahajan,K.N., Nick McElhinny.S.A., Mitchell,B.S. and Ramsden,D.A. (2002) Association of DNA polymerase mu (pol mu) with Ku and ligase IV: Role for pol mu in end-joining double-strand break repair. Mol. Cell. Biol., 22, 5194-5202.
-
Mahajan,K.N., Nick McElhinny.S.A., Mitchell,B.S. and Ramsden,D.A. (2002) Association of DNA polymerase mu (pol mu) with Ku and ligase IV: Role for pol mu in end-joining double-strand break repair. Mol. Cell. Biol., 22, 5194-5202.
-
-
-
-
22
-
-
23044453811
-
-
Nick McElhinny.S.A., Havener,J.M., Garcia-Diaz,M., Juarez,R., Bebenek,K., Kee,B.L., Blanco,L., Kunkel,T.A. and Ramsden,D.A. (2005) A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining. Mol. Cell, 19, 357-366.
-
Nick McElhinny.S.A., Havener,J.M., Garcia-Diaz,M., Juarez,R., Bebenek,K., Kee,B.L., Blanco,L., Kunkel,T.A. and Ramsden,D.A. (2005) A gradient of template dependence defines distinct biological roles for family X polymerases in nonhomologous end joining. Mol. Cell, 19, 357-366.
-
-
-
-
23
-
-
35748960204
-
-
Moon,A.F., Garcia-Diaz,M., Batra,V.K., Beard,W.A., Bebenek.K., Kunkel,T.A., Wilson,S.H. and Pedersen,L.C. (2007) The X family portrait: structural insights into biological functions of X family polymerases. DNA Repair, 6, 1709-1725.
-
Moon,A.F., Garcia-Diaz,M., Batra,V.K., Beard,W.A., Bebenek.K., Kunkel,T.A., Wilson,S.H. and Pedersen,L.C. (2007) The X family portrait: structural insights into biological functions of X family polymerases. DNA Repair, 6, 1709-1725.
-
-
-
-
24
-
-
10044252241
-
The DNA-polymerase-X family: Controllers of DNA quality?
-
Ramadan,K., Shevelev,I. and Hubscher,U. (2004) The DNA-polymerase-X family: Controllers of DNA quality? Nat. Rev. Mol. Cell Biol., 5, 1038-1043.
-
(2004)
Nat. Rev. Mol. Cell Biol
, vol.5
, pp. 1038-1043
-
-
Ramadan, K.1
Shevelev, I.2
Hubscher, U.3
-
25
-
-
0028049441
-
Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP
-
Pelletier,H., Sawaya,M.R., Kumar,A., Wilson,S.H. and Kraut,J. (1994) Structures of ternary complexes of rat DNA polymerase beta, a DNA template-primer, and ddCTP. Science, 264, 1891-1903.
-
(1994)
Science
, vol.264
, pp. 1891-1903
-
-
Pelletier, H.1
Sawaya, M.R.2
Kumar, A.3
Wilson, S.H.4
Kraut, J.5
-
26
-
-
0028338562
-
Studies of gapped DNA substrate binding by mammalian DNA polymerase beta. Dependence on 5′-phosphate group
-
Prasad,R., Beard,W.A. and Wilson,S.H. (1994) Studies of gapped DNA substrate binding by mammalian DNA polymerase beta. Dependence on 5′-phosphate group. J. Biol. Chem., 269, 18096-18101.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 18096-18101
-
-
Prasad, R.1
Beard, W.A.2
Wilson, S.H.3
-
27
-
-
0030930760
-
Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: Evidence for an induced fit mechanism
-
Sawaya,M.R., Prasad,R., Wilson,S.H., Kraut,J. and Pelletier,H. (1997) Crystal structures of human DNA polymerase beta complexed with gapped and nicked DNA: Evidence for an induced fit mechanism. Biochemistry 36, 11205-11215.
-
(1997)
Biochemistry
, vol.36
, pp. 11205-11215
-
-
Sawaya, M.R.1
Prasad, R.2
Wilson, S.H.3
Kraut, J.4
Pelletier, H.5
-
28
-
-
24144492384
-
Characterization of SpPo14, a unique X-family DNA polymerase in Schizosaccharomyces pombe
-
González-Barrera,S., Sánchez,A., Ruiz,J.F., Juárez,R., Picher,A.J., Terrados,G., Andrade,P. and Blanco,L. (2005) Characterization of SpPo14, a unique X-family DNA polymerase in Schizosaccharomyces pombe. Nucleic Acids Res., 33, 4762-4774.
-
(2005)
Nucleic Acids Res
, vol.33
, pp. 4762-4774
-
-
González-Barrera, S.1
Sánchez, A.2
Ruiz, J.F.3
Juárez, R.4
Picher, A.J.5
Terrados, G.6
Andrade, P.7
Blanco, L.8
-
29
-
-
37549024225
-
Intrinsic 5′-deoxyribose-5-phosphate lyase activity in Saccharomyces cerevisiae Trf4 protein with a possible role in base excision DNA repair
-
Gellon,L., Carson,D.R., Carson,J.P. and Demple,B. (2008) Intrinsic 5′-deoxyribose-5-phosphate lyase activity in Saccharomyces cerevisiae Trf4 protein with a possible role in base excision DNA repair. DNA Repair, 7, 187-198.
-
(2008)
DNA Repair
, vol.7
, pp. 187-198
-
-
Gellon, L.1
Carson, D.R.2
Carson, J.P.3
Demple, B.4
-
30
-
-
0031046294
-
A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins
-
Bork,P., Hofmarm,K., Bucher,P., Neuwald,A.F., Altschul,S.F. and Koonin,E.V. (1997) A superfamily of conserved domains in DNA damage-responsive cell cycle checkpoint proteins. FASEB J., 11 68-76.
-
(1997)
FASEB J
, vol.11
, pp. 68-76
-
-
Bork, P.1
Hofmarm, K.2
Bucher, P.3
Neuwald, A.F.4
Altschul, S.F.5
Koonin, E.V.6
-
31
-
-
0030731108
-
The complete genome sequence of the gram-positive bacterium Bacillus subtilis
-
Kunst,F., Ogasawara,N., Moszer,I., Albertini,A.M., Alloni,G., Azevedo,V., Bertero,M.G., Bessieres,P., Bolotin,A., Borchert,S. et al. (1997) The complete genome sequence of the gram-positive bacterium Bacillus subtilis. Nature, 390, 249-256.
-
(1997)
Nature
, vol.390
, pp. 249-256
-
-
Kunst, F.1
Ogasawara, N.2
Moszer, I.3
Albertini, A.M.4
Alloni, G.5
Azevedo, V.6
Bertero, M.G.7
Bessieres, P.8
Bolotin, A.9
Borchert, S.10
-
32
-
-
0032529457
-
Phosphoesterase domains associated with DNA polymerases of diverse origins
-
Aravind,L. and Koonin,E.V. (1998) Phosphoesterase domains associated with DNA polymerases of diverse origins. Nucleic Acids Res., 26 3746-3752.
-
(1998)
Nucleic Acids Res
, vol.26
, pp. 3746-3752
-
-
Aravind, L.1
Koonin, E.V.2
-
33
-
-
0022431897
-
Characterization of a ′-5′ exonuclease activity in the phage ø29-encoded DNA polymerase
-
Blanco,L. and Salas,M. (1985) Characterization of a ′-5′ exonuclease activity in the phage ø29-encoded DNA polymerase. Nucleic Acids Res., 13, 1239-1249.
-
(1985)
Nucleic Acids Res
, vol.13
, pp. 1239-1249
-
-
Blanco, L.1
Salas, M.2
-
34
-
-
0021088139
-
Improved conditions for activity gel analysis of DNA polymerase catalytic polypeptides
-
Karawya,E., Swack,J.A. and Wilson,S.H. (1983) Improved conditions for activity gel analysis of DNA polymerase catalytic polypeptides. Anal. Biochem., 135, 318-325.
-
(1983)
Anal. Biochem
, vol.135
, pp. 318-325
-
-
Karawya, E.1
Swack, J.A.2
Wilson, S.H.3
-
35
-
-
0024474078
-
A conserved 3′-5′ exonuclease active site in prokaryotic and eukaryotic DNA polymerases
-
Bernad,A., Blanco,L., Lázaro,J.M., Martin,G. and Salas,M. (1989) A conserved 3′-5′ exonuclease active site in prokaryotic and eukaryotic DNA polymerases. Cell, 59, 219-228.
-
(1989)
Cell
, vol.59
, pp. 219-228
-
-
Bernad, A.1
Blanco, L.2
Lázaro, J.M.3
Martin, G.4
Salas, M.5
-
36
-
-
33644841882
-
DNA polymerase X from Deinococcus radiodurans possesses a structure-modulated 3′->5′ exonuclease activity involved in radioresistance
-
Blasius,M., Shevelev,I., Jolivet,E., Sommer,S, and Hübscher,U. (2006) DNA polymerase X from Deinococcus radiodurans possesses a structure-modulated 3′->5′ exonuclease activity involved in radioresistance. Mol. Microbiol., 60, 165-176.
-
(2006)
Mol. Microbiol
, vol.60
, pp. 165-176
-
-
Blasius, M.1
Shevelev, I.2
Jolivet, E.3
Sommer, S.4
Hübscher, U.5
-
37
-
-
0026794640
-
The bacteriophage ø29 DNA polymerase, a proofreading enzyme
-
Garmendia,C., Bernad,A., Esteban,J.A., Blanco,L. and Salas,M. (1992) The bacteriophage ø29 DNA polymerase, a proofreading enzyme. J. Biol. Chem., 267, 2594-2599.
-
(1992)
J. Biol. Chem
, vol.267
, pp. 2594-2599
-
-
Garmendia, C.1
Bernad, A.2
Esteban, J.A.3
Blanco, L.4
Salas, M.5
-
38
-
-
0020981110
-
Identification of the epsilon-subunit of Escherichia coli DNA polymerase III holoenzyme as the dnaQ gene product: A fidelity subunit for DNA replication
-
Scheuennann,R., Tam,S., Burgers,P.M., Lu,C. and Echols,H. (1983) Identification of the epsilon-subunit of Escherichia coli DNA polymerase III holoenzyme as the dnaQ gene product: A fidelity subunit for DNA replication. Proc. Natl Acad. Sci. USA, 80, 7085-7089.
-
(1983)
Proc. Natl Acad. Sci. USA
, vol.80
, pp. 7085-7089
-
-
Scheuennann, R.1
Tam, S.2
Burgers, P.M.3
Lu, C.4
Echols, H.5
-
39
-
-
33744952342
-
The NH2-terminal php domain of the alpha subunit of the Escherichia coli replicase binds the epsilon proofreading subunit
-
Wieczorek,A. and McHenry,C.S. (2006) The NH2-terminal php domain of the alpha subunit of the Escherichia coli replicase binds the epsilon proofreading subunit. J. Biol. Chem., 281, 12561-12567.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 12561-12567
-
-
Wieczorek, A.1
McHenry, C.S.2
-
40
-
-
0037402602
-
Crystal structure of the Escherichia coli YcdX protein reveals a trinuclear zinc active site
-
Teplyakov,A., Obmolova,G., Khil,P.P., Howard,A.J., Camerini-Otero, R.D. and Gilliland,G.L. (2003) Crystal structure of the Escherichia coli YcdX protein reveals a trinuclear zinc active site. Proteins, 51, 315-318.
-
(2003)
Proteins
, vol.51
, pp. 315-318
-
-
Teplyakov, A.1
Obmolova, G.2
Khil, P.P.3
Howard, A.J.4
Camerini-Otero, R.D.5
Gilliland, G.L.6
-
41
-
-
32144432437
-
The SWISSMODEL workspace: A web-based environment for protein structure homology modelling
-
Arnold,K., Bordoli,L., Kopp,J. and Schwede,J. (2006) The SWISSMODEL workspace: A web-based environment for protein structure homology modelling. Bioinformatics, 22, 195-201.
-
(2006)
Bioinformatics
, vol.22
, pp. 195-201
-
-
Arnold, K.1
Bordoli, L.2
Kopp, J.3
Schwede, J.4
-
42
-
-
0031473847
-
SWISS-MODEL and the SwissPdbViewer: An environment for comparative protein modeling
-
Guex,N. and Peitsch,M.C. (1997) SWISS-MODEL and the SwissPdbViewer: An environment for comparative protein modeling. Electrophoresis, 18, 2714-2723.
-
(1997)
Electrophoresis
, vol.18
, pp. 2714-2723
-
-
Guex, N.1
Peitsch, M.C.2
-
43
-
-
0042622380
-
SWISSMODEL: An automated protein homology-modeling server
-
Schwede,T., Kopp,J., Guex,N. and Peitsch,M.C. (2003) SWISSMODEL: An automated protein homology-modeling server. Nucleic Acids Res., 31, 3381-3385.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 3381-3385
-
-
Schwede, T.1
Kopp, J.2
Guex, N.3
Peitsch, M.C.4
-
44
-
-
0033106244
-
Evaluation and improvement of multiple sequence methods for protein secondary structure prediction
-
Cuff,J.A. and Barton,G.J. (1999) Evaluation and improvement of multiple sequence methods for protein secondary structure prediction. Proteins 34, 508-519.
-
(1999)
Proteins
, vol.34
, pp. 508-519
-
-
Cuff, J.A.1
Barton, G.J.2
-
45
-
-
0034663597
-
Application of multiple sequence alignment profiles to improve protein secondary structure prediction
-
Cuff,J.A. and Barton,G.J. (2000) Application of multiple sequence alignment profiles to improve protein secondary structure prediction. Proteins, 40, 502-511.
-
(2000)
Proteins
, vol.40
, pp. 502-511
-
-
Cuff, J.A.1
Barton, G.J.2
-
46
-
-
0032420333
-
JPred: A consensus secondary structure prediction server
-
Cuff,J.A., Clamp,M.E., Siddiqui,A.S., Finlay,M. and Barton,G.J. (1998) JPred: A consensus secondary structure prediction server. Bioinformatics, 14, 892-893.
-
(1998)
Bioinformatics
, vol.14
, pp. 892-893
-
-
Cuff, J.A.1
Clamp, M.E.2
Siddiqui, A.S.3
Finlay, M.4
Barton, G.J.5
-
47
-
-
0024290491
-
Exonucleolytic proofreading
-
Kunkel,T.A. (1988) Exonucleolytic proofreading. Cell, 53, 837-840.
-
(1988)
Cell
, vol.53
, pp. 837-840
-
-
Kunkel, T.A.1
-
48
-
-
0344668821
-
Mutagenesis of human DNA polymerase lambda: Essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities
-
Shevelev,I., Blanca,G., Villani,G., Ramadan,K., Spadari,S., Hübscher,U. and Maga,G. (2003) Mutagenesis of human DNA polymerase lambda: Essential roles of Tyr505 and Phe506 for both DNA polymerase and terminal transferase activities. Nucleic Acids Res., 31, 6916-6925.
-
(2003)
Nucleic Acids Res
, vol.31
, pp. 6916-6925
-
-
Shevelev, I.1
Blanca, G.2
Villani, G.3
Ramadan, K.4
Spadari, S.5
Hübscher, U.6
Maga, G.7
-
49
-
-
0037066719
-
DNA polymerase lambda, a novel DNA repair enzyme in human cells
-
García-Díaz,M., Bebenek,K., Sabariegos,R., Domínguez,O., Rodríguez,J., Kirchhoff,T., García-Palomero,E., Picher,A.J., Juárez,R., Ruiz,J.F. et al. (2002) DNA polymerase lambda, a novel DNA repair enzyme in human cells. J. Biol. Chem., 277, 13184-13191.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 13184-13191
-
-
García-Díaz, M.1
Bebenek, K.2
Sabariegos, R.3
Domínguez, O.4
Rodríguez, J.5
Kirchhoff, T.6
García-Palomero, E.7
Picher, A.J.8
Juárez, R.9
Ruiz, J.F.10
-
50
-
-
33750041949
-
A specific loop in human DNA polymerase μ allows switching between creative and DNA-instructed synthesis
-
Juárez,R., Ruiz,J.F., Nick McElhinny,S.A., Ramsden,D. and Blanco,L. (2006) A specific loop in human DNA polymerase μ allows switching between creative and DNA-instructed synthesis. Nucleic Acids Res., 34, 4572-4582.
-
(2006)
Nucleic Acids Res
, vol.34
, pp. 4572-4582
-
-
Juárez, R.1
Ruiz, J.F.2
Nick McElhinny, S.A.3
Ramsden, D.4
Blanco, L.5
-
51
-
-
0027179827
-
Short gap-filling synthesis by DNA polymerase beta is processive
-
Singhal,R.K. and Wilson,S.H. (1993) Short gap-filling synthesis by DNA polymerase beta is processive. J. Biol. Chem., 268, 15906-15911.
-
(1993)
J. Biol. Chem
, vol.268
, pp. 15906-15911
-
-
Singhal, R.K.1
Wilson, S.H.2
-
52
-
-
33745087407
-
A coproofreading Zn(2+)-dependent exonuclease within a bacterial replicase
-
Stano,N.M., Chen,J. and McHenry,C.S. (2006) A coproofreading Zn(2+)-dependent exonuclease within a bacterial replicase. Nat. Struct. Mol. Biol., 13, 458-459.
-
(2006)
Nat. Struct. Mol. Biol
, vol.13
, pp. 458-459
-
-
Stano, N.M.1
Chen, J.2
McHenry, C.S.3
-
53
-
-
33748146483
-
Crystal structure of the catalytic alpha subunit of E. coli replicative DNA polymerase III
-
Lamers,M.H., Georgescu,R.E., Lee,S.G., O'Donnell,M. and Kuriyan,J. (2006) Crystal structure of the catalytic alpha subunit of E. coli replicative DNA polymerase III. Cell, 126, 881-892.
-
(2006)
Cell
, vol.126
, pp. 881-892
-
-
Lamers, M.H.1
Georgescu, R.E.2
Lee, S.G.3
O'Donnell, M.4
Kuriyan, J.5
-
54
-
-
33748146034
-
The structure of T. aquaticus DNA polymerase III is distinct from eukaryotic replicative DNA polymerases
-
Bailey,S., Wing,R.A. and Steitz,T.A. (2006) The structure of T. aquaticus DNA polymerase III is distinct from eukaryotic replicative DNA polymerases. Cell, 126, 893-904.
-
(2006)
Cell
, vol.126
, pp. 893-904
-
-
Bailey, S.1
Wing, R.A.2
Steitz, T.A.3
-
55
-
-
0029892846
-
Evidence for an imino intermediate in the DNA polymerase beta deoxyribose phosphate excision reaction
-
Piersen,C.E., Prasad,R., Wilson,S.H. and Lloyd,R.S. (1996) Evidence for an imino intermediate in the DNA polymerase beta deoxyribose phosphate excision reaction. J. Biol. Chem., 271, 17811-17815.
-
(1996)
J. Biol. Chem
, vol.271
, pp. 17811-17815
-
-
Piersen, C.E.1
Prasad, R.2
Wilson, S.H.3
Lloyd, R.S.4
-
56
-
-
0034714096
-
DNA polymerase lambda (Pol lambda), a novel eukaryotic DNA polymerase with a potential role in meiosis
-
García-Díaz,M., Domínguez,O., López-Fernández,L.A., de Lera,L.T., Saniger,M.L., Ruiz,J.F., Párraga,M., García-Ortiz,M.J., Kirchhoff,T., del Mazo,J. et al. (2000) DNA polymerase lambda (Pol lambda), a novel eukaryotic DNA polymerase with a potential role in meiosis. J. Mol. Biol., 301, 851-867.
-
(2000)
J. Mol. Biol
, vol.301
, pp. 851-867
-
-
García-Díaz, M.1
Domínguez, O.2
López-Fernández, L.A.3
de Lera, L.T.4
Saniger, M.L.5
Ruiz, J.F.6
Párraga, M.7
García-Ortiz, M.J.8
Kirchhoff, T.9
del Mazo, J.10
-
57
-
-
0037193544
-
Epistatic analysis of the roles of the RAD27 and POL4 gene products in DNA base excision repair in S. cerevisiae
-
McInnis,M., O'Neill,G., Fossum,K. and Reagan,M.S. (2002) Epistatic analysis of the roles of the RAD27 and POL4 gene products in DNA base excision repair in S. cerevisiae. DNA Repair, 1, 311-315.
-
(2002)
DNA Repair
, vol.1
, pp. 311-315
-
-
McInnis, M.1
O'Neill, G.2
Fossum, K.3
Reagan, M.S.4
-
58
-
-
1842289240
-
Characterization of an African swine fever virus 20-kDa DNA polymerase involved in DNA repair
-
Oliveros,M., Yáñez,R.J., Salas,M.L., Salas,J., Viñuela,E. and Blanco,L. (1997) Characterization of an African swine fever virus 20-kDa DNA polymerase involved in DNA repair. J. Biol. Chem., 272, 30899-30910.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 30899-30910
-
-
Oliveros, M.1
Yáñez, R.J.2
Salas, M.L.3
Salas, J.4
Viñuela, E.5
Blanco, L.6
-
59
-
-
54949155081
-
-
Friedberg,E.C., Walker,G.C. and Siede,W. (1995) DNA Repair and Mutagenesis, Washington, DC, ASM Press ASM Press, Washington, DC.
-
Friedberg,E.C., Walker,G.C. and Siede,W. (1995) DNA Repair and Mutagenesis, Washington, DC, ASM Press ASM Press, Washington, DC.
-
-
-
-
60
-
-
52649177781
-
Dynamics of DNA double-strand break repair in Bacillus subtilis
-
Graumann,P, ed, Caister Academic Press, Norfolk, pp
-
Sánchez,H., Carrasco,B., Ayora,S. and Alonso,J.C. (2007) Dynamics of DNA double-strand break repair in Bacillus subtilis. In Graumann,P. (ed.) Bacillus. Cellular and Molecular Biology. Caister Academic Press, Norfolk, pp. 43-63.
-
(2007)
Bacillus. Cellular and Molecular Biology
, pp. 43-63
-
-
Sánchez, H.1
Carrasco, B.2
Ayora, S.3
Alonso, J.C.4
-
61
-
-
1342324026
-
DNA glycosylase recognition and catalysis
-
Fromme,J.C., Banerjee,A. and Verdine,G.L. (2004) DNA glycosylase recognition and catalysis. Curr. Opin. Struct. Biol., 14, 43-49.
-
(2004)
Curr. Opin. Struct. Biol
, vol.14
, pp. 43-49
-
-
Fromme, J.C.1
Banerjee, A.2
Verdine, G.L.3
-
63
-
-
0041836116
-
YqfS from Bacillus subtilis is a spore protein and a new functional member of the type IV apurinic/apyrimidinic-endonuclease family
-
Salas-Pacheco,J.M., Urtiz-Estrada,N., Martínez-Cadena,G., Yasbin,R.E. and Pedraza-Reyes,M. (2003) YqfS from Bacillus subtilis is a spore protein and a new functional member of the type IV apurinic/apyrimidinic-endonuclease family. J. Bacteriol., 185, 5380-5390.
-
(2003)
J. Bacteriol
, vol.185
, pp. 5380-5390
-
-
Salas-Pacheco, J.M.1
Urtiz-Estrada, N.2
Martínez-Cadena, G.3
Yasbin, R.E.4
Pedraza-Reyes, M.5
-
64
-
-
0033193618
-
Characterization of Bacillus subtilis ExoA protein: A multifunctional DNA-repair enzyme similar to the Escherichia coli exonuclease III
-
Shida,T., Ogawa,T., Ogasawara,N. and Sekiguchi,J. (1999) Characterization of Bacillus subtilis ExoA protein: A multifunctional DNA-repair enzyme similar to the Escherichia coli exonuclease III. Biosci. Biotechnol. Biochem., 63, 1528-1534.
-
(1999)
Biosci. Biotechnol. Biochem
, vol.63
, pp. 1528-1534
-
-
Shida, T.1
Ogawa, T.2
Ogasawara, N.3
Sekiguchi, J.4
-
65
-
-
0037216802
-
Forespore-specific expression of Bacillus subtilis yqfS, which encodes type IV apurinic/apyrimidinic endonuclease, a component of the base excision repair pathway
-
Urtiz-Estrada,N., Salas-Pacheco,J.M., Yasbin,R.E. and Pedraza-Reyes,M. (2003) Forespore-specific expression of Bacillus subtilis yqfS, which encodes type IV apurinic/apyrimidinic endonuclease, a component of the base excision repair pathway. J. Bacteriol., 185, 340-348.
-
(2003)
J. Bacteriol
, vol.185
, pp. 340-348
-
-
Urtiz-Estrada, N.1
Salas-Pacheco, J.M.2
Yasbin, R.E.3
Pedraza-Reyes, M.4
-
66
-
-
27144549864
-
Role of the Nfo (YqfS) and ExoA apurinic/apyrimidinic endonucleases in protecting Bacillus subtilis spores from DNA damage
-
Salas-Pacheco,J.M., Setlow,B., Setlow,P. and Pedraza-Reyes,M. (2005) Role of the Nfo (YqfS) and ExoA apurinic/apyrimidinic endonucleases in protecting Bacillus subtilis spores from DNA damage. J. Bacteriol., 187, 7374-7381.
-
(2005)
J. Bacteriol
, vol.187
, pp. 7374-7381
-
-
Salas-Pacheco, J.M.1
Setlow, B.2
Setlow, P.3
Pedraza-Reyes, M.4
-
67
-
-
0035097388
-
Functional analysis of the Bacillus subtilis yshD gene, a mutS paralogue
-
Rossolillo,P. and Albertini,A.M. (2001) Functional analysis of the Bacillus subtilis yshD gene, a mutS paralogue. Mol. Gen. Genet. 264, 809-818.
-
(2001)
Mol. Gen. Genet
, vol.264
, pp. 809-818
-
-
Rossolillo, P.1
Albertini, A.M.2
-
68
-
-
0031054975
-
Ku selectively transfers between DNA molecules with homologous ends
-
Bliss,T.M. and Lane,D.P. (1997) Ku selectively transfers between DNA molecules with homologous ends. J. Biol. Chem., 272, 5765-5773.
-
(1997)
J. Biol. Chem
, vol.272
, pp. 5765-5773
-
-
Bliss, T.M.1
Lane, D.P.2
-
69
-
-
0032518680
-
Ku protein stimulates DNA end joining by mammalian DNA ligases: A direct role for Ku in repair of DNA doubte-strand breaks
-
Ramsden,D.A. and Gellert,M. (1998) Ku protein stimulates DNA end joining by mammalian DNA ligases: A direct role for Ku in repair of DNA doubte-strand breaks. EMBO J., 17, 609-614.
-
(1998)
EMBO J
, vol.17
, pp. 609-614
-
-
Ramsden, D.A.1
Gellert, M.2
-
70
-
-
0035833552
-
Structure of the Ku heterodimer bound to DNA and its implications for double-strand breák repair
-
Walker,J.R., Corpina,R.A. and Goldberg,J. (2001) Structure of the Ku heterodimer bound to DNA and its implications for double-strand breák repair. Nature, 412, 607-614.
-
(2001)
Nature
, vol.412
, pp. 607-614
-
-
Walker, J.R.1
Corpina, R.A.2
Goldberg, J.3
-
71
-
-
0942268167
-
Repair of DNA double strand breaks by non-homologous end joining
-
Lees-Miller,S.P. and Meek,K. (2003) Repair of DNA double strand breaks by non-homologous end joining. Biochimie, 85, 1161-1173.
-
(2003)
Biochimie
, vol.85
, pp. 1161-1173
-
-
Lees-Miller, S.P.1
Meek, K.2
-
72
-
-
29244463205
-
Nonhomologous end joining in yeast
-
Daley,J.M., Palmbos,P.L., Wu,D. and Wilson,T.E. (2005) Nonhomologous end joining in yeast. Annu. Rev. Genet., 39, 431-451.
-
(2005)
Annu. Rev. Genet
, vol.39
, pp. 431-451
-
-
Daley, J.M.1
Palmbos, P.L.2
Wu, D.3
Wilson, T.E.4
-
73
-
-
7944231563
-
Non-homologous end-joining factors of Saccharomyces cerevisiae
-
Dudasova,Z., Dudas,A. and Chovanec,M. (2004) Non-homologous end-joining factors of Saccharomyces cerevisiae. FEMS Microbiol. Rev., 28 581-601.
-
(2004)
FEMS Microbiol. Rev
, vol.28
, pp. 581-601
-
-
Dudasova, Z.1
Dudas, A.2
Chovanec, M.3
-
74
-
-
0242272059
-
Mending the break: Two DNA double-strand break repair machines in eukaryotes
-
Krejci,L., Chen,L., Van Komen,S., Sung,P. and Tomkinson,A. (2003) Mending the break: Two DNA double-strand break repair machines in eukaryotes. Prog. Nucleic Acid Res. Mol. Biol., 74, 159-201.
-
(2003)
Prog. Nucleic Acid Res. Mol. Biol
, vol.74
, pp. 159-201
-
-
Krejci, L.1
Chen, L.2
Van Komen, S.3
Sung, P.4
Tomkinson, A.5
-
75
-
-
0034889360
-
Prokaryotic homologs of the eukaryotic DNA-end-binding protein Ku, novel domains in the Ku protein and prediction of a prokaryotic double-strand break repair system
-
Aravind,L. and Koonin,E.V. (2001) Prokaryotic homologs of the eukaryotic DNA-end-binding protein Ku, novel domains in the Ku protein and prediction of a prokaryotic double-strand break repair system. Genome Res., 11, 1365-1374.
-
(2001)
Genome Res
, vol.11
, pp. 1365-1374
-
-
Aravind, L.1
Koonin, E.V.2
-
76
-
-
0035816444
-
Identification of bacterial homologues of the Ku DNA repair proteins
-
Doherty,A.J., Jackson,S.P. and Weller,G.R. (2001) Identification of bacterial homologues of the Ku DNA repair proteins. FEBS Lett., 500, 186-188.
-
(2001)
FEBS Lett
, vol.500
, pp. 186-188
-
-
Doherty, A.J.1
Jackson, S.P.2
Weller, G.R.3
-
77
-
-
0033759217
-
Bacterial homologs of the small subunit of eukaryotic DNA primase
-
Koonin,E.V., Wolf,Y.I., Kondrashov,A.S, and Aravind,L. (2000) Bacterial homologs of the small subunit of eukaryotic DNA primase. J. Mol. Microbiol. Biotechnol., 2, 509-512.
-
(2000)
J. Mol. Microbiol. Biotechnol
, vol.2
, pp. 509-512
-
-
Koonin, E.V.1
Wolf, Y.I.2
Kondrashov, A.S.3
Aravind, L.4
-
78
-
-
0035860377
-
A family of DNA repair ligases in bacteria?
-
Weher,G.R. and Doherty,A.J. (2001) A family of DNA repair ligases in bacteria? FEBS Lett., 505, 340-342.
-
(2001)
FEBS Lett
, vol.505
, pp. 340-342
-
-
Weher, G.R.1
Doherty, A.J.2
-
79
-
-
7444269607
-
Mycobacterial Ku and ligase proteins constitute a two-component NHEJ repair machine
-
Della,M., Palmbos,P.L., Tseng,H.M., Tonkin,L.M., Daley,J.M., Topper,L.M., Pitcher,R.S., Tomkinson,A.E., Wilson,T.E. and Doherty,A.J. (2004) Mycobacterial Ku and ligase proteins constitute a two-component NHEJ repair machine. Science, 306, 683-685.
-
(2004)
Science
, vol.306
, pp. 683-685
-
-
Della, M.1
Palmbos, P.L.2
Tseng, H.M.3
Tonkin, L.M.4
Daley, J.M.5
Topper, L.M.6
Pitcher, R.S.7
Tomkinson, A.E.8
Wilson, T.E.9
Doherty, A.J.10
-
80
-
-
0032476658
-
Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination
-
Furuse,M., Nagase,Y., Tsubouchi,H., Murakami-Murofushi,K., Shibata,T. and Ohta,K. (1998) Distinct roles of two separable in vitro activities of yeast Mre11 in mitotic and meiotic recombination. EMBO J., 17, 6412-6425.
-
(1998)
EMBO J
, vol.17
, pp. 6412-6425
-
-
Furuse, M.1
Nagase, Y.2
Tsubouchi, H.3
Murakami-Murofushi, K.4
Shibata, T.5
Ohta, K.6
-
81
-
-
0032931844
-
The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance
-
Moreau,S., Ferguson,J.R. and Symington,L.S. (1999) The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance. Mol. Cell. Biol., 19, 556-566.
-
(1999)
Mol. Cell. Biol
, vol.19
, pp. 556-566
-
-
Moreau, S.1
Ferguson, J.R.2
Symington, L.S.3
-
82
-
-
0032085295
-
The 3′ to 5′ exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks
-
Paull,T.T. and Gellert,M. (1998) The 3′ to 5′ exonuclease activity of Mre 11 facilitates repair of DNA double-strand breaks. Mol. Cell 1, 969-979.
-
(1998)
Mol. Cell
, vol.1
, pp. 969-979
-
-
Paull, T.T.1
Gellert, M.2
-
83
-
-
0035929667
-
DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex
-
Trujillo,K.M. and Sung,P. (2001) DNA structure-specific nuclease activities in the Saccharomyces cerevisiae Rad50*Mre11 complex. J. Biol. Chem., 276, 35458-35464.
-
(2001)
J. Biol. Chem
, vol.276
, pp. 35458-35464
-
-
Trujillo, K.M.1
Sung, P.2
-
84
-
-
0032555480
-
Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95
-
Trujillo,K.M., Yuan,S.S., Lee,E.Y. and Sung,P. (1998) Nuclease activities in a complex of human recombination and DNA repair factors Rad50, Mre11, and p95. J. Biol. Chem., 273, 21447-21450.
-
(1998)
J. Biol. Chem
, vol.273
, pp. 21447-21450
-
-
Trujillo, K.M.1
Yuan, S.S.2
Lee, E.Y.3
Sung, P.4
-
85
-
-
0032567108
-
Complex formation and functional versatility of Mre11 of budding yeast in recombination
-
Usui,T., Ohta,T., Oshiumi,H., Tomizawa,J., Ogawa,H. and Ogawa,T. (1998) Complex formation and functional versatility of Mre11 of budding yeast in recombination. Cell, 95, 705-716.
-
(1998)
Cell
, vol.95
, pp. 705-716
-
-
Usui, T.1
Ohta, T.2
Oshiumi, H.3
Tomizawa, J.4
Ogawa, H.5
Ogawa, T.6
-
86
-
-
33745810160
-
Distinct enzymic functional groups are required for the phospbomonoesterase and phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase/ phosphatase
-
Keppetipola,N. and Shuman,S. (2006) Distinct enzymic functional groups are required for the phospbomonoesterase and phosphodiesterase activities of Clostridium thermocellum polynucleotide kinase/ phosphatase. J. Biol. Chem., 281, 19251-19259.
-
(2006)
J. Biol. Chem
, vol.281
, pp. 19251-19259
-
-
Keppetipola, N.1
Shuman, S.2
-
87
-
-
0030089480
-
The sbcC and sbcD genes of Escherichia coli encode a nuclease involved in palindrome inviability and genetic recombination
-
Connelly,J.C. and Leach,D.R. (1996) The sbcC and sbcD genes of Escherichia coli encode a nuclease involved in palindrome inviability and genetic recombination. Genes Cells, 1, 285-291.
-
(1996)
Genes Cells
, vol.1
, pp. 285-291
-
-
Connelly, J.C.1
Leach, D.R.2
-
88
-
-
34250847224
-
Structural and biochemical characterization of a novel Mn2 + -dependent phosphodiesterase encoded by the yfcE gene
-
Miller,D.J., Shuvalova,L., Evdokimova,E., Savchenko,A., Yakunin,A.F. and Anderson,W.F. (2007) Structural and biochemical characterization of a novel Mn2 + -dependent phosphodiesterase encoded by the yfcE gene. Protein Sci., 16, 1338-1348.
-
(2007)
Protein Sci
, vol.16
, pp. 1338-1348
-
-
Miller, D.J.1
Shuvalova, L.2
Evdokimova, E.3
Savchenko, A.4
Yakunin, A.F.5
Anderson, W.F.6
|