DNA polymerase λ mediates a back-up base excision repair activity in extracts of mouse embryonic fibroblasts

Journal of Biological Chemistry

Volumn 280, Issue 18, 2005, Pages 18469-18475

  Braithwaite, Elena K ^a   Prasad, Rajendra ^a   Shock, David D ^a   Hou, Esther W ^a   Beard, William A ^a   Wilson, Samuel H ^a,b  

^a NATIONAL INSTITUTE OF ENVIRONMENTAL HEALTH SCIENCES   (United States)

^b NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; DNA; POLYMERS;

BASE EXCISION REPAIR (BER); DNA POLYMERASE; ENZYMATIC ACTIVITIES; MAMMALIAN DNA;

ENZYMES;

ACTIN; DEOXYRIBONUCLEASE I; DNA DIRECTED DNA POLYMERASE BETA; DNA POLYMERASE; DNA POLYMERASE LAMBDA; DOUBLE STRANDED DNA; NEUTRALIZING ANTIBODY; UNCLASSIFIED DRUG; DNA POLYMERASE BETA2;

ANIMAL CELL; ARTICLE; AUTORADIOGRAPHY; CHEMOLUMINESCENCE; CONTROLLED STUDY; DNA REPAIR; EMBRYO; ENZYME ACTIVITY; ENZYME STRUCTURE; EXCISION REPAIR; FIBROBLAST; GENE OVEREXPRESSION; GENETIC MANIPULATION; MOUSE; NONHUMAN; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN PROCESSING; WESTERN BLOTTING; WILD TYPE; ANIMAL; CELL LINE; COMPARATIVE STUDY; CYTOLOGY; ENZYMOLOGY; GENETICS; HUMAN; MOUSE MUTANT; PHYSIOLOGY;

ANIMALIA; MAMMALIA;

ANIMALS; CELL LINE; DNA POLYMERASE BETA; DNA REPAIR; EMBRYO; FIBROBLASTS; HUMANS; MICE; MICE, KNOCKOUT;

EID: 23444444813     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M411864200     Document Type: Article

References (40)

1. Krokan, H. E., Nilsen, H., Skorpen, F., Otterlei, M., and Slupphaug, G. (2000) FEBS Lett. 476, 73-77
2. Sobol, R. W., Horton, J. K., Kuhn, R., Gu, H., Singhal, R. K., Prasad, R., Rajewsky, K., and Wilson, S. H. (1996) Nature 379, 183-186
3. Horton, J. K., Joyce-Gray, D. F., Pachkowski, B. F., Swenberg, J. A., and Wilson, S. H. (2003) DNA Repair 2, 27-48
4. Fortini, P., Parlanti, E., Sidorkina, O. M., Laval, J., and Dogliotti, E. (1999) J. Biol. Chem. 274, 15230-15236
5. Nealon, K., Nicholl, I. D., and Kenny, M. K. (1996) Nucleic Acids Res. 24, 3763-3770
6. Singhal, R. K., Prasad, R., and Wilson, S. H. (1995) J. Biol. Chem. 270, 949-957
7. Dianov, G., Price, A., and Lindahl, T. (1992) Mol. Cell. Biol. 12, 1605-1612
8. Dianov, G., Bischoff, C., Piotrowski, J., and Bohr, V. A. (1998) J. Biol. Chem. 273, 33811-33816
9. Miller, M. R., and Chinault, D. N. (1982) J. Biol. Chem. 257, 10204-10209
10. Garcia-Diaz, M., Dominguez, O., Lopez-Fernandez, L. A., de Lera, L. T., Saniger, M. L., Ruiz, J. F., Parraga, M., Garcia-Ortiz, M. J., Kirchhoff, T., del Mazo, J., Bernad, A., and Blanco, L. (2000) J. Mol. Biol. 301, 851-867
11. Nagasawa, K., Kitamura, K., Yasui, A., Nimura, Y., Ikeda, K., Hirai, M., Matsukage, A., and Nakanishi, M. (2000) J. Biol. Chem. 275, 31233-31238
12. Prasad, R., Widen, S. G., Singhal, R. K., Watkins, J., Prakash, L., and Wilson, S. H. (1993) Nucleic Acids Res. 21, 5301-5307
13. Shimizu, K., Santocanale, C., Ropp, P. A., Longhese, M. P., Plevani, P., Lucchini, G., and Sugino, A. (1993) J. Biol. Chem. 268, 27148-27153
14. Aoufouchi, S., Flatter, E., Dahan, A., Faili, A., Bertocci, B., Storck, S., Delbos, F., Cocea, L., Gupta, N., Weill, J. C., and Reynaud, C. A. (2000) Nucleic Acids Res. 28, 3684-3693
15. Garcia-Diaz, M., Bebenek, K., Krahn, J. M., Blanco, L., Kunkel, T. A., and Pedersen, L. C. (2004) Mol. Cell 13, 561-572
16. Garcia-Diaz, M., Bebenek, K., Sabariegos, R., Dominguez, O., Rodriguez, J., Kirchhoff, T., Garcia-Palomero, E., Picher, A. J., Juarez, R., Ruiz, J. F., Kunkel, T. A., and Blanco, L. (2002) J. Biol. Chem. 277, 13184-13191
17. Garcia-Diaz, M., Bebenek, K., Kunkel, T. A., and Blanco, L. (2001) J. Biol. Chem. 276, 34659-34663
18. Lee, J. W., Blanco, L., Zhou, T., Garcia-Diaz, M., Bebenek, K., Kunkel, T. A., Wang, Z., and Povirk, L. F. (2004) J. Biol. Chem. 279, 805-811
19. Tseng, H. M., and Tomkinson, A. E. (2002) J. Biol. Chem. 277, 45630-45637
20. Wilson, T. E., and Lieber, M. R. (1999) J. Biol. Chem. 274, 23599-23609
21. Ramadan, K., Shevelev, I. V., Maga, G., and Hubscher, U. (2002) J. Biol. Chem. 277, 18454-18458
22. Ramadan, K., Maga, G., Shevelev, I. V., Villani, G., Blanco, L., and Hubscher, U. (2003) J. Mol. Biol. 328, 63-72
23. Strauss, P. R., Beard, W. A., Patterson, T. A., and Wilson, S. H. (1997) J. Biol. Chem. 272, 1302-1307
24. Abbotts, J., SenGupta, D. N., Zmudzka, B., Widen, S. G., Notario, V., and Wilson, S. H. (1988) Biochemistry 27, 901-909
25. Kumar, A., Widen, S. G., Williams, K. R., Kedar, P., Karpel, R. L., and Wilson, S. H. (1990) J. Biol. Chem. 265, 2124-2131
26. Slupphaug, G., Eftedal, I., Kavli, B., Bharati, S., Helle, N. M., Haug, T., Levine, D. W., and Krokan, H. E. (1995) Biochemistry 34, 128-138
27. Wang, Y. C., Burkhart, W. A., Mackey, Z. B., Moyer, M. B., Ramos, W., Husain, I., Chen, J., Besterman, J. M., and Tomkinson, A. E. (1994) J. Biol. Chem. 269, 31923-31928
28. Harlow, E., and Lane, D. (1988) Antibodies: A Laboratory Manual, Cold Spring Harbor Laboratory Press, Cold Spring Harbor, NY
29. Bertocci, B., De Smet, A., Flatter, E., Dahan, A., Bories, J. C., Landreau, C., Weill, J. C., and Reynaud, C. A. (2002) J. Immunol. 168, 3702-3706
30. Sobol, R. W., Prasad, R., Evenski, A., Baker, A., Yang, X. P., Horton, J. K., and Wilson, S. H. (2000) Nature 405, 807-810
31. Kedar, P. S., Kim, S. J., Robertson, A., Hou, E., Prasad, R., Horton, J. K., and Wilson, S. H. (2002) J. Biol. Chem. 277, 31115-31123
32. Horton, J. K., Baker, A., Berg, B. J., Sobol, R. W., and Wilson, S. H. (2002) DNA Repair 1, 317-333
33. Srivastava, D. K., Berg, B. J., Prasad, R., Molina, J. T., Beard, W. A., Tomkinson, A. E., and Wilson, S. H. (1998) J. Biol. Chem. 273, 21203-21209
34. Lee, M. Y., and Toomey, N. L. (1986) Nucleic Acids Res. 14, 1719-1726
35. Ling, H., Sayer, J. M., Plosky, B. S., Yagi, H., Boudsocq, F., Woodgate, R., Jerina, D. M., and Yang, W. (2004) Proc. Natl. Acad. Sci. U. S. A. 101, 2265-2269
36. Matsumoto, Y., Kim, K., and Bogenhagen, D. F. (1994) Mol. Cell. Biol. 14, 6187-6197
37. Biade, S., Sobol, R. W., Wilson, S. H., and Matsumoto, Y. (1998) J. Biol. Chem. 273, 898-902
38. Stucki, M., Pascucci, B., Parlanti, E., Fortini, P., Wilson, S. H., Hubscher, U., and Dogliotti, E. (1998) Oncogene 17, 835-843
39. Fortini, P., Pascucci, B., Parlanti, E., Sobol, R. W., Wilson, S. H., and Dogliotti, E. (1998) Biochemistry 37, 3575-3580
40. Fortini, P., Pascucci, B., Belisario, F., and Dogliotti, E. (2000) Nucleic Acids Res. 28, 3040-3046