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Volumn 6, Issue 3, 2004, Pages 281-293

Postmortem studies in Parkinson's disease

Author keywords

Cellular stress; Dopaminergic neuron; Etiology; Lewy body formation; Parkinson's disease; Pathogenesis; Postmortem study

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; ALPHA SYNUCLEIN; AMINO ACID TRANSFER RNA LIGASE; CALBINDIN; CASPASE 3; CYTOKINE; DOPAMINE TRANSPORTER; ENDOTHELIN RECEPTOR; FAS ASSOCIATED DEATH DOMAIN PROTEIN; GAMMA INTERFERON; HEAT SHOCK PROTEIN; INTERLEUKIN 1BETA; MEMBRANE PROTEIN; PARKIN; PARKIN ASSOCIATED ENDOTHELIN LIKE RECEPTOR; PROTEASOME; PROTEIN GLUTAMINE GAMMA GLUTAMYLTRANSFERASE; SYNPHILIN 1; TUMOR NECROSIS FACTOR ALPHA; TUMOR NECROSIS FACTOR ALPHA RECEPTOR; UBIQUITIN; UNCLASSIFIED DRUG; VESICULAR MONOAMINE TRANSPORTER 2; VESICULAR TRANSPORT PROTEIN;

EID: 5444225223     PISSN: 12948322     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (71)

References (136)
  • 1
    • 0000015266 scopus 로고
    • The occurrence, distribution and physiological role of catecholamines in the nervous system
    • Carlsson A. The occurrence, distribution and physiological role of catecholamines in the nervous system. Pharmacol Rev. 1959;11(2, Part 2):490-493.
    • (1959) Pharmacol Rev , vol.11 , Issue.2 PART 2 , pp. 490-493
    • Carlsson, A.1
  • 2
    • 34250928307 scopus 로고
    • Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system
    • Ehringer H, Hornykiewicz O. Distribution of noradrenaline and dopamine (3-hydroxytyramine) in the human brain and their behavior in diseases of the extrapyramidal system [in German]. Klin Wochenschr. 1960;38:1236-1239.
    • (1960) Klin Wochenschr , vol.38 , pp. 1236-1239
    • Ehringer, H.1    Hornykiewicz, O.2
  • 3
    • 0015745743 scopus 로고
    • Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations
    • Bernheimer H, Birkmayer W, Hornykiewicz O, Jellinger K, Seitelberger F. Brain dopamine and the syndromes of Parkinson and Huntington. Clinical, morphological and neurochemical correlations. J Neurol Sci. 1973;20:415-455.
    • (1973) J Neurol Sci , vol.20 , pp. 415-455
    • Bernheimer, H.1    Birkmayer, W.2    Hornykiewicz, O.3    Jellinger, K.4    Seitelberger, F.5
  • 4
    • 0023740954 scopus 로고
    • Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease
    • Hirsch E, Graybiel AM, Agid YA. Melanized dopaminergic neurons are differentially susceptible to degeneration in Parkinson's disease. Nature. 1988;334:345-348.
    • (1988) Nature , vol.334 , pp. 345-348
    • Hirsch, E.1    Graybiel, A.M.2    Agid, Y.A.3
  • 5
    • 0030744876 scopus 로고    scopus 로고
    • Mutation in the α-synuclein gene identified in families with Parkinson's disease
    • Polymeropoulos MH, Lavedan C, Leroy E, et al. Mutation in the α-synuclein gene identified in families with Parkinson's disease. Science. 1997;276:2045-2047.
    • (1997) Science , vol.276 , pp. 2045-2047
    • Polymeropoulos, M.H.1    Lavedan, C.2    Leroy, E.3
  • 6
    • 0032499264 scopus 로고    scopus 로고
    • Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
    • Kitada T, Asakawa S, Hattori N, et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature. 1998;392:605-608.
    • (1998) Nature , vol.392 , pp. 605-608
    • Kitada, T.1    Asakawa, S.2    Hattori, N.3
  • 7
    • 0037428241 scopus 로고    scopus 로고
    • Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism
    • Bonifati V, Rizzu P, van Baren MJ, et al. Mutations in the DJ-1 gene associated with autosomal recessive early-onset parkinsonism. Science. 2003;299:256-259.
    • (2003) Science , vol.299 , pp. 256-259
    • Bonifati, V.1    Rizzu, P.2    Van Baren, M.J.3
  • 8
    • 0032190090 scopus 로고    scopus 로고
    • The ubiquitin pathway in Parkinson's disease
    • Leroy E, Boyer R, Auburger G, et al. The ubiquitin pathway in Parkinson's disease. Nature. 1998;395:451-452.
    • (1998) Nature , vol.395 , pp. 451-452
    • Leroy, E.1    Boyer, R.2    Auburger, G.3
  • 9
    • 12144289221 scopus 로고    scopus 로고
    • UCHL1 is a Parkinson's disease susceptibility gene
    • Maraganore DM, Lesnick TG, Elbaz A, et al. UCHL1 is a Parkinson's disease susceptibility gene. Ann Neurol. 2004;55:512-521.
    • (2004) Ann Neurol , vol.55 , pp. 512-521
    • Maraganore, D.M.1    Lesnick, T.G.2    Elbaz, A.3
  • 10
    • 0031990490 scopus 로고    scopus 로고
    • Ala30Pro mutation in the gene encoding a-synuclein in Parkinson's disease
    • Krüger R, Kuhn W, Muller T, et al. Ala30Pro mutation in the gene encoding a-synuclein in Parkinson's disease. Nat Genet. 1998;18:106-108.
    • (1998) Nat Genet , vol.18 , pp. 106-108
    • Krüger, R.1    Kuhn, W.2    Muller, T.3
  • 11
    • 10744230149 scopus 로고    scopus 로고
    • The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia
    • Zarranz JJ, Alegre J, Gomez-Esteban JC, et al. The new mutation, E46K, of α-synuclein causes Parkinson and Lewy body dementia. Ann Neurol. 2004;55:164-173.
    • (2004) Ann Neurol , vol.55 , pp. 164-173
    • Zarranz, J.J.1    Alegre, J.2    Gomez-Esteban, J.C.3
  • 12
    • 0035880458 scopus 로고    scopus 로고
    • α-synuclein gene haplotypes are associated with Parkinson's disease
    • Farrer M, Maraganore DM, Lockhart P, et al. α-Synuclein gene haplotypes are associated with Parkinson's disease. Hum Mol Genet. 2001;10:1847-1851.
    • (2001) Hum Mol Genet , vol.10 , pp. 1847-1851
    • Farrer, M.1    Maraganore, D.M.2    Lockhart, P.3
  • 13
    • 0037426704 scopus 로고    scopus 로고
    • Asynuclein promoter and risk of Parkinson's disease: Microsatellite and allelic size variability
    • Tan EK, Tan C, Shen H, et al. Asynuclein promoter and risk of Parkinson's disease: microsatellite and allelic size variability. Neurosci Lett. 2003;336:70-72.
    • (2003) Neurosci Lett , vol.336 , pp. 70-72
    • Tan, E.K.1    Tan, C.2    Shen, H.3
  • 14
    • 5644284321 scopus 로고    scopus 로고
    • Polymorphisms of the α-synuclein promoter: Expression analyses and association studies in Parkinson's disease
    • Holzmann C, Kruger R, Saecker AM, et al. Polymorphisms of the α-synuclein promoter: expression analyses and association studies in Parkinson's disease. J Neural Transm. 2003;110:67-76.
    • (2003) J Neural Transm , vol.110 , pp. 67-76
    • Holzmann, C.1    Kruger, R.2    Saecker, A.M.3
  • 15
    • 10744227740 scopus 로고    scopus 로고
    • Comparison of kindreds with parkinsonism and α-synuclein genomic multiplications
    • Farrer M, Kachergus J, Forno L, et al. Comparison of kindreds with parkinsonism and α-synuclein genomic multiplications. Ann Neurol. 2004;55:174-179.
    • (2004) Ann Neurol , vol.55 , pp. 174-179
    • Farrer, M.1    Kachergus, J.2    Forno, L.3
  • 16
    • 0242300619 scopus 로고    scopus 로고
    • α-synuclein locus triplication causes Parkinson's disease
    • Singleton AB, Farrer M, Johnson J, et al. α-Synuclein locus triplication causes Parkinson's disease. Science. 2003;302:841.
    • (2003) Science , vol.302 , pp. 841
    • Singleton, A.B.1    Farrer, M.2    Johnson, J.3
  • 17
    • 0035964758 scopus 로고    scopus 로고
    • Altered expression of the synuclein family mRNA in Lewy body and Alzheimer's disease
    • Rockenstein E, Hansen LA, Mallory M, et al. Altered expression of the synuclein family mRNA in Lewy body and Alzheimer's disease. Brain Res. 2000;914:48-56.
    • (2000) Brain Res , vol.914 , pp. 48-56
    • Rockenstein, E.1    Hansen, L.A.2    Mallory, M.3
  • 18
    • 0032849237 scopus 로고    scopus 로고
    • Cellular co-localization of phosphorylated tau- and NACP/α- synuclein-epitopes in Lewy bodies in sporadic Parkinson's disease and in dementia with Lewy bodies
    • Arima K, Hirai S, Sunohara N, et al. Cellular co-localization of phosphorylated tau- and NACP/α-synuclein-epitopes in Lewy bodies in sporadic Parkinson's disease and in dementia with Lewy bodies. Brain Res. 1999;843:53-61.
    • (1999) Brain Res , vol.843 , pp. 53-61
    • Arima, K.1    Hirai, S.2    Sunohara, N.3
  • 19
    • 0031941058 scopus 로고    scopus 로고
    • Aggregation of α-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies
    • Baba M, Nakajo S, Tu PH, et al. Aggregation of α-synuclein in Lewy bodies of sporadic Parkinson's disease and dementia with Lewy bodies. Am J Pathol. 1998;152:879-884.
    • (1998) Am J Pathol , vol.152 , pp. 879-884
    • Baba, M.1    Nakajo, S.2    Tu, P.H.3
  • 20
    • 0031944830 scopus 로고    scopus 로고
    • Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain α-synuclein immunoreactivity
    • Irizarry MC, Growdon W, Gomez-Isla T, et al. Nigral and cortical Lewy bodies and dystrophic nigral neurites in Parkinson's disease and cortical Lewy body disease contain α-synuclein immunoreactivity. J Neuropathol Exp Neurol. 1998;57:334-337.
    • (1998) J Neuropathol Exp Neurol , vol.57 , pp. 334-337
    • Irizarry, M.C.1    Growdon, W.2    Gomez-Isla, T.3
  • 21
    • 0031794794 scopus 로고    scopus 로고
    • A synuclein is present in Lewy bodies in sporadic Parkinson's disease
    • Mezey E, Dehejia AM, Harta G, et al. A synuclein is present in Lewy bodies in sporadic Parkinson's disease. Mol Psychiatry. 1998;3:493-499.
    • (1998) Mol Psychiatry , vol.3 , pp. 493-499
    • Mezey, E.1    Dehejia, A.M.2    Harta, G.3
  • 22
    • 0032568534 scopus 로고    scopus 로고
    • α-synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies
    • Spillantini MG, Crowther RA, Jakes R, et al. α-Synuclein in filamentous inclusions of Lewy bodies from Parkinson's disease and dementia with Lewy bodies. Proc Natl Acad Sci USA. 1998;95:6469-6473.
    • (1998) Proc Natl Acad Sci USA , vol.95 , pp. 6469-6473
    • Spillantini, M.G.1    Crowther, R.A.2    Jakes, R.3
  • 23
    • 0025807172 scopus 로고
    • Epitopes located in spatially separate domains of each neurofilament subunit are present in Parkinson's disease Lewy bodies
    • Hill WD, Lee VM, Hurtig HI, Murray JM, Trojanowski JQ. Epitopes located in spatially separate domains of each neurofilament subunit are present in Parkinson's disease Lewy bodies. J Comp Neurol. 1991;309:150-160.
    • (1991) J Comp Neurol , vol.309 , pp. 150-160
    • Hill, W.D.1    Lee, V.M.2    Hurtig, H.I.3    Murray, J.M.4    Trojanowski, J.Q.5
  • 25
    • 0025326719 scopus 로고
    • Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases
    • Lowe J, McDermott H, Landon M, Mayer RJ, Wilkinson KD. Ubiquitin carboxyl-terminal hydrolase (PGP 9.5) is selectively present in ubiquitinated inclusion bodies characteristic of human neurodegenerative diseases. J Pathol. 1990;161:153-160.
    • (1990) J Pathol , vol.161 , pp. 153-160
    • Lowe, J.1    McDermott, H.2    Landon, M.3    Mayer, R.J.4    Wilkinson, K.D.5
  • 27
    • 0029688041 scopus 로고    scopus 로고
    • Electron microscopy of Lewy bodies in the amygdala-parahippocampal region. Comparison with inclusion bodies in the MPTP-treated squirrel monkey
    • Forno LS, DeLanney LE, Irwin I, et al. Electron microscopy of Lewy bodies in the amygdala-parahippocampal region. Comparison with inclusion bodies in the MPTP-treated squirrel monkey. Adv Neurol. 1996;69:217-228.
    • (1996) Adv Neurol , vol.69 , pp. 217-228
    • Forno, L.S.1    DeLanney, L.E.2    Irwin, I.3
  • 29
    • 0034602442 scopus 로고    scopus 로고
    • Oxidative damage linked to neurodegeneration by selective a-synuclein nitration in synucleinopathy lesions
    • Giasson BI, Duda JE, Murray IV, et al. Oxidative damage linked to neurodegeneration by selective a-synuclein nitration in synucleinopathy lesions. Science. 2000;290:985-989.
    • (2000) Science , vol.290 , pp. 985-989
    • Giasson, B.I.1    Duda, J.E.2    Murray, I.V.3
  • 30
    • 0034703336 scopus 로고    scopus 로고
    • TorsinA accumulation in Lewy bodies in sporadic Parkinson's disease
    • Shashidharan P, Good PF, Hsu A, et al. TorsinA accumulation in Lewy bodies in sporadic Parkinson's disease. Brain Res. 2000;877:379-381.
    • (2000) Brain Res , vol.877 , pp. 379-381
    • Shashidharan, P.1    Good, P.F.2    Hsu, A.3
  • 31
    • 0036095285 scopus 로고    scopus 로고
    • Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies
    • Schlossmacher MG, Frosch MP, Gai WP, et al. Parkin localizes to the Lewy bodies of Parkinson disease and dementia with Lewy bodies. Am J Pathol. 2002;160:1655-1667.
    • (2002) Am J Pathol , vol.160 , pp. 1655-1667
    • Schlossmacher, M.G.1    Frosch, M.P.2    Gai, W.P.3
  • 32
    • 10744224035 scopus 로고    scopus 로고
    • Pael-R is accumulated in Lewy bodies of Parkinson's disease
    • Murakami T, Shoji M, Imai Y, et al. Pael-R is accumulated in Lewy bodies of Parkinson's disease. Ann Neurol. 2004;55:439-442.
    • (2004) Ann Neurol , vol.55 , pp. 439-442
    • Murakami, T.1    Shoji, M.2    Imai, Y.3
  • 34
    • 10744220754 scopus 로고    scopus 로고
    • The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: Linking protein biosynthesis and neurodegeneration
    • Corti O, Hampe C, Koutnikova H, et al. The p38 subunit of the aminoacyl-tRNA synthetase complex is a Parkin substrate: linking protein biosynthesis and neurodegeneration. Hum Mol Genet. 2003;12:1427-1437.
    • (2003) Hum Mol Genet , vol.12 , pp. 1427-1437
    • Corti, O.1    Hampe, C.2    Koutnikova, H.3
  • 35
    • 0042886045 scopus 로고    scopus 로고
    • Cell cycle aberrations by α-synuclein overexpression and cyclin B immunoreactivity in Lewy bodies
    • Lee SS, Kim YM, Junn E, et al. Cell cycle aberrations by α-synuclein overexpression and cyclin B immunoreactivity in Lewy bodies. Neurobiol Aging. 2003;24:687-696.
    • (2003) Neurobiol Aging , vol.24 , pp. 687-696
    • Lee, S.S.1    Kim, Y.M.2    Junn, E.3
  • 36
    • 0037452813 scopus 로고    scopus 로고
    • Tissue transglutaminase-induced aggregation of α-synuclein: Implications for Lewy body formation in Parkinson's disease and dementia with Lewy bodies
    • Junn E, Ronchetti RD, Quezado MM, Kim SY, Mouradian MM. Tissue transglutaminase-induced aggregation of α-synuclein: implications for Lewy body formation in Parkinson's disease and dementia with Lewy bodies. Proc Natl Acad Sci U S A. 2003;100:2047-2052.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 2047-2052
    • Junn, E.1    Ronchetti, R.D.2    Quezado, M.M.3    Kim, S.Y.4    Mouradian, M.M.5
  • 37
    • 0035795205 scopus 로고    scopus 로고
    • Parkin immunoreactivity in the brain of human and non-human primates: An immunohistochemical analysis in normal conditions and in parkinsonian syndromes
    • Zarate-Lagunes M, Gu WJ, Blanchard V, et al. Parkin immunoreactivity in the brain of human and non-human primates: an immunohistochemical analysis in normal conditions and in parkinsonian syndromes. J Comp Neurol. 2001;432:184-196.
    • (2001) J Comp Neurol , vol.432 , pp. 184-196
    • Zarate-Lagunes, M.1    Gu, W.J.2    Blanchard, V.3
  • 38
    • 0032957883 scopus 로고    scopus 로고
    • Immunohistochemical and subcellular localization of Parkin protein: Absence of protein in autosomal recessive juvenile parkinsonism patients
    • Shimura H, Hattori N, Kubo S, et al. Immunohistochemical and subcellular localization of Parkin protein: absence of protein in autosomal recessive juvenile parkinsonism patients. Ann Neurol. 1999;45:668-672.
    • (1999) Ann Neurol , vol.45 , pp. 668-672
    • Shimura, H.1    Hattori, N.2    Kubo, S.3
  • 39
    • 0033814671 scopus 로고    scopus 로고
    • An autopsy case of autosomal-recessive juvenile parkinsonism with a homozygous exon 4 deletion in the parkin gene
    • Hayashi S, Wakabayashi K, Ishikawa A, et al. An autopsy case of autosomal-recessive juvenile parkinsonism with a homozygous exon 4 deletion in the parkin gene. Mov Disord. 2000;15:884-888.
    • (2000) Mov Disord , vol.15 , pp. 884-888
    • Hayashi, S.1    Wakabayashi, K.2    Ishikawa, A.3
  • 40
    • 0034848395 scopus 로고    scopus 로고
    • Lewy bodies and parkinsonism in families with parkin mutations
    • Farrer M, Chan P, Chen R, et al. Lewy bodies and parkinsonism in families with parkin mutations. Ann Neurol. 2001;50:293-300.
    • (2001) Ann Neurol , vol.50 , pp. 293-300
    • Farrer, M.1    Chan, P.2    Chen, R.3
  • 41
    • 10744224738 scopus 로고    scopus 로고
    • The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease
    • Bandopadhyay R, Kingsbury AE, Cookson MR, et al. The expression of DJ-1 (PARK7) in normal human CNS and idiopathic Parkinson's disease. Brain. 2004;127(Pt 2):420-430.
    • (2004) Brain , vol.127 , Issue.PART 2 , pp. 420-430
    • Bandopadhyay, R.1    Kingsbury, A.E.2    Cookson, M.R.3
  • 42
    • 9144257938 scopus 로고    scopus 로고
    • DJ-1 colocalizes with tau inclusions: A link between parkinsonism and dementia
    • Rizzu P, Hinkle DA, Zhukareva V, et al. DJ-1 colocalizes with tau inclusions: a link between parkinsonism and dementia. Ann Neurol. 2004;55:113-118.
    • (2004) Ann Neurol , vol.55 , pp. 113-118
    • Rizzu, P.1    Hinkle, D.A.2    Zhukareva, V.3
  • 43
    • 0034681163 scopus 로고    scopus 로고
    • Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease: Implications for pathogenesis and therapy
    • Conway KA, Lee SJ, Rochet JC, et al. Acceleration of oligomerization, not fibrillization, is a shared property of both α-synuclein mutations linked to early-onset Parkinson's disease: implications for pathogenesis and therapy. Proc Natl Acad Sci U S A. 2000;97:571-576.
    • (2000) Proc Natl Acad Sci U S A , vol.97 , pp. 571-576
    • Conway, K.A.1    Lee, S.J.2    Rochet, J.C.3
  • 44
    • 0035834360 scopus 로고    scopus 로고
    • Kinetic stabilization of α-synuclein protofibril by dopamine-α-synuclein adduct
    • Conway KA, Pchet JC, Bieganski RM, et al. Kinetic stabilization of α-synuclein protofibril by dopamine-α-synuclein adduct. Science. 2001;294:1346-1349.
    • (2001) Science , vol.294 , pp. 1346-1349
    • Conway, K.A.1    Pchet, J.C.2    Bieganski, R.M.3
  • 45
    • 0031474418 scopus 로고    scopus 로고
    • Contribution of somal Lewy bodies to neuronal death
    • Tompkins MM, Hill WD. Contribution of somal Lewy bodies to neuronal death. Brain Res. 1997;775:24-29.
    • (1997) Brain Res , vol.775 , pp. 24-29
    • Tompkins, M.M.1    Hill, W.D.2
  • 46
    • 0023898945 scopus 로고
    • The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease
    • Gibb WR, Lees AJ. The relevance of the Lewy body to the pathogenesis of idiopathic Parkinson's disease. J Neurol Neurosurg Psychiatry. 1988;51:745-752.
    • (1988) J Neurol Neurosurg Psychiatry , vol.51 , pp. 745-752
    • Gibb, W.R.1    Lees, A.J.2
  • 47
    • 0028096074 scopus 로고
    • Stability of cell size and nucleolar size in Lewy body containing neurons of substantia nigra in Parkinson's disease
    • Gertz HJ, Siegers A, Kuchinke J. Stability of cell size and nucleolar size in Lewy body containing neurons of substantia nigra in Parkinson's disease. Brain Res. 1994;637:339-341.
    • (1994) Brain Res , vol.637 , pp. 339-341
    • Gertz, H.J.1    Siegers, A.2    Kuchinke, J.3
  • 48
    • 0025815998 scopus 로고
    • Pathological changes in dendrites of substantia nigra neurons in Parkinson's disease: A Golgi study
    • Patt S, Gertz HJ, Gerhard L, et al. Pathological changes in dendrites of substantia nigra neurons in Parkinson's disease: a Golgi study. Histol Histopathol. 1991;6:373-380.
    • (1991) Histol Histopathol , vol.6 , pp. 373-380
    • Patt, S.1    Gertz, H.J.2    Gerhard, L.3
  • 49
    • 0030215482 scopus 로고    scopus 로고
    • Altered neurofilament expression does not contribute to Lewy body formation
    • Hill WD. Altered neurofilament expression does not contribute to Lewy body formation. Am J Pathol. 1996;149:728-729.
    • (1996) Am J Pathol , vol.149 , pp. 728-729
    • Hill, W.D.1
  • 50
    • 12944250987 scopus 로고    scopus 로고
    • Caspase-3: A vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease
    • Hartmann A, Hunot S, Michel PP, et al. Caspase-3: a vulnerability factor and final effector in apoptotic death of dopaminergic neurons in Parkinson's disease. Proc Natl Acad Sci USA. 2000;97:2875-2880.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 2875-2880
    • Hartmann, A.1    Hunot, S.2    Michel, P.P.3
  • 51
    • 0035224695 scopus 로고    scopus 로고
    • Parkinson's disease. The apoptosis hypothesis revisited
    • Hartmann A, Hirsch EC. Parkinson's disease. The apoptosis hypothesis revisited. Adv Neurol. 2001;86:143-153.
    • (2001) Adv Neurol , vol.86 , pp. 143-153
    • Hartmann, A.1    Hirsch, E.C.2
  • 53
    • 0030614372 scopus 로고    scopus 로고
    • Selective degeneration of Purkinje cells with Lewy body-like inclusions in aged NFHLACZ transgenic mice
    • Tu PH, Robinson KA, de Snoo F, et al. Selective degeneration of Purkinje cells with Lewy body-like inclusions in aged NFHLACZ transgenic mice. J Neurosci. 1997;17:1064-7104.
    • (1997) J Neurosci , vol.17 , pp. 1064-7104
    • Tu, P.H.1    Robinson, K.A.2    De Snoo, F.3
  • 54
    • 0034705015 scopus 로고    scopus 로고
    • α-synuclein cortical Lewy body correlate with dementia in Parkinson's disease
    • Hurtig HI, Trojanowski JQ, Galvin J, et al. α-Synuclein cortical Lewy body correlate with dementia in Parkinson's disease. Neurology. 2000;54:1916-1921.
    • (2000) Neurology , vol.54 , pp. 1916-1921
    • Hurtig, H.I.1    Trojanowski, J.Q.2    Galvin, J.3
  • 55
    • 0033923545 scopus 로고    scopus 로고
    • α-synuclein-immunoreactive cortical impairment in Parkinson's disease
    • Mattila PM, Rinne JO, Helenius H, et al. α-Synuclein-immunoreactive cortical impairment in Parkinson's disease. Acts Neuropathol (Berl). 2000;100:285-290.
    • (2000) Acts Neuropathol (Berl) , vol.100 , pp. 285-290
    • Mattila, P.M.1    Rinne, J.O.2    Helenius, H.3
  • 57
    • 0025954066 scopus 로고
    • Ageing and Parkinson's disease: Substantia nigra regional selectivity
    • Fearnley JM, Lees AJ. Ageing and Parkinson's disease: substantia nigra regional selectivity. Brain. 1991;114(Pt 5):2283-2301.
    • (1991) Brain , vol.114 , Issue.PART 5 , pp. 2283-2301
    • Fearnley, J.M.1    Lees, A.J.2
  • 58
    • 0032816549 scopus 로고    scopus 로고
    • The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease
    • Damier P, Hirsch EC, Agid Y, Graybiel AM. The substantia nigra of the human brain. II. Patterns of loss of dopamine-containing neurons in Parkinson's disease. Brain. 1999;122(Pt 8):1437-1448.
    • (1999) Brain , vol.122 , Issue.PART 8 , pp. 1437-1448
    • Damier, P.1    Hirsch, E.C.2    Agid, Y.3    Graybiel, A.M.4
  • 59
    • 0032865590 scopus 로고    scopus 로고
    • The substantia nigra of the human brain. I. Nigrosomes and the nigral matrix, a compartmental organization based on calbindin D(28K) immunohistochemistry
    • Damier P, Hirsch EC, Agid Y, Graybiel AM. The substantia nigra of the human brain. I. Nigrosomes and the nigral matrix, a compartmental organization based on calbindin D(28K) immunohistochemistry. Brain. 1999;122(Pt 8):1421-1436.
    • (1999) Brain , vol.122 , Issue.PART 8 , pp. 1421-1436
    • Damier, P.1    Hirsch, E.C.2    Agid, Y.3    Graybiel, A.M.4
  • 60
    • 0026712160 scopus 로고
    • Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: Sparing of calbindin-D28k-containing cells
    • German DC, Manaye KF, Sonsalla PK, et al. Midbrain dopaminergic cell loss in Parkinson's disease and MPTP-induced parkinsonism: sparing of calbindin-D28k-containing cells. Ann N Y Acad Sci. 1992;648:42-62.
    • (1992) Ann N Y Acad Sci , vol.648 , pp. 42-62
    • German, D.C.1    Manaye, K.F.2    Sonsalla, P.K.3
  • 61
    • 0028278417 scopus 로고
    • Sparing of the dopaminergic neurons containing calbindin-D28k and of the dopaminergic mesocortical projections in weaver mutant mice
    • Gaspar P, Ben Jelloun N, Febvret A. Sparing of the dopaminergic neurons containing calbindin-D28k and of the dopaminergic mesocortical projections in weaver mutant mice. Neuroscience. 1994;61:293-305.
    • (1994) Neuroscience , vol.61 , pp. 293-305
    • Gaspar, P.1    Ben Jelloun, N.2    Febvret, A.3
  • 62
    • 0030601734 scopus 로고    scopus 로고
    • Midbrain dopaminergic neurons in the mouse: Co-localization with calbindin-D28K and calretinin
    • Liang CL, Sinton CM, German DC. Midbrain dopaminergic neurons in the mouse: co-localization with calbindin-D28K and calretinin. Neuroscience. 1996;75:523-533.
    • (1996) Neuroscience , vol.75 , pp. 523-533
    • Liang, C.L.1    Sinton, C.M.2    German, D.C.3
  • 63
    • 0025358695 scopus 로고
    • Specific reduction of calcium-binding protein (28-kilodalton calbindin-D) gene expression in aging and neurodegenerative diseases
    • Iacopino AM, Christakos S. Specific reduction of calcium-binding protein (28-kilodalton calbindin-D) gene expression in aging and neurodegenerative diseases. Proc Natl Acad Sci USA. 1990;87:4078-4082.
    • (1990) Proc Natl Acad Sci USA , vol.87 , pp. 4078-4082
    • Iacopino, A.M.1    Christakos, S.2
  • 64
    • 0031059220 scopus 로고    scopus 로고
    • Vulnerability of midbrain dopaminergic neurons in calbindin-D28k- deficient mice: Lack of evidence for a neuroprotective role of endogenous calbindin in MPTP-treated and weaver mice
    • Airaksinen MS, Thoenen H, Meyer M. Vulnerability of midbrain dopaminergic neurons in calbindin-D28k-deficient mice: lack of evidence for a neuroprotective role of endogenous calbindin in MPTP-treated and weaver mice. Eur J Neurosci. 1997;9:120-127.
    • (1997) Eur J Neurosci , vol.9 , pp. 120-127
    • Airaksinen, M.S.1    Thoenen, H.2    Meyer, M.3
  • 65
    • 0030782462 scopus 로고    scopus 로고
    • Dopamine transporter mRNA levels are high in midbrain neurons vulnerable to MPTP
    • Sanghera MK, Manaye K, McMahon A, Sonsalla PK, German DC. Dopamine transporter mRNA levels are high in midbrain neurons vulnerable to MPTP. Neuroreport. 1997;8:3327-3331.
    • (1997) Neuroreport , vol.8 , pp. 3327-3331
    • Sanghera, M.K.1    Manaye, K.2    McMahon, A.3    Sonsalla, P.K.4    German, D.C.5
  • 66
    • 0031979752 scopus 로고    scopus 로고
    • Hypothesis: The role of dopaminergic transporters in selective vulnerability of cells in Parkinson's disease
    • Uhl GR. Hypothesis: the role of dopaminergic transporters in selective vulnerability of cells in Parkinson's disease. Ann Neurol. 1998;43:555-560.
    • (1998) Ann Neurol , vol.43 , pp. 555-560
    • Uhl, G.R.1
  • 67
    • 0033030440 scopus 로고    scopus 로고
    • Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease
    • Miller GW, Erickson JD, Perez JT, et al. Immunochemical analysis of vesicular monoamine transporter (VMAT2) protein in Parkinson's disease. Exp Neurol. 1999;156:138-148.
    • (1999) Exp Neurol , vol.156 , pp. 138-148
    • Miller, G.W.1    Erickson, J.D.2    Perez, J.T.3
  • 68
    • 0030929663 scopus 로고    scopus 로고
    • Immunochemical analysis of dopamine transporter protein in Parkinson's disease
    • Miller GW, Heilman CJ, Perez JT, et al. Immunochemical analysis of dopamine transporter protein in Parkinson's disease. Ann Neurol. 1997;41:530-539.
    • (1997) Ann Neurol , vol.41 , pp. 530-539
    • Miller, G.W.1    Heilman, C.J.2    Perez, J.T.3
  • 69
    • 0026532177 scopus 로고
    • Dopamine transporter mRNA: Dense expression in ventral midbrain neurons
    • Shimada S, Kitayama S, Walther D, et al. Dopamine transporter mRNA: dense expression in ventral midbrain neurons. Mol Brain Res. 1992;13:359-362.
    • (1992) Mol Brain Res , vol.13 , pp. 359-362
    • Shimada, S.1    Kitayama, S.2    Walther, D.3
  • 70
    • 0028215940 scopus 로고
    • Dopamine transporter messenger RNA in Parkinson's disease and control substantia nigra neurons
    • Uhl GR, Walther D, Mash D, et al. Dopamine transporter messenger RNA in Parkinson's disease and control substantia nigra neurons. Ann Neurol. 1994;35:494-498.
    • (1994) Ann Neurol , vol.35 , pp. 494-498
    • Uhl, G.R.1    Walther, D.2    Mash, D.3
  • 71
    • 0037451858 scopus 로고    scopus 로고
    • Attentuation of dopamine transporter activity by α-synuclein
    • Wersinger C, Sidhu A. Attentuation of dopamine transporter activity by α-synuclein. Neurosci Lett. 2003;340:189-192.
    • (2003) Neurosci Lett , vol.340 , pp. 189-192
    • Wersinger, C.1    Sidhu, A.2
  • 72
    • 0035066885 scopus 로고    scopus 로고
    • Direct binding and functional coupling of α-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis
    • Lee FJ, Liu F, Pristupa ZB, Niznik HB. Direct binding and functional coupling of α-synuclein to the dopamine transporters accelerate dopamine-induced apoptosis. FASEB J. 2001;15:916-926.
    • (2001) FASEB J , vol.15 , pp. 916-926
    • Lee, F.J.1    Liu, F.2    Pristupa, Z.B.3    Niznik, H.B.4
  • 73
    • 0036884733 scopus 로고    scopus 로고
    • Pathogenesis of Parkinson's disease: Dopamine, vesicles and α-synuclein
    • Lotharius J, Brundin P. Pathogenesis of Parkinson's disease: dopamine, vesicles and α-synuclein. Nat Rev Neurosci. 2002;3:932-942.
    • (2002) Nat Rev Neurosci , vol.3 , pp. 932-942
    • Lotharius, J.1    Brundin, P.2
  • 74
    • 0032867676 scopus 로고    scopus 로고
    • The 26S proteasome: A molecular machine designed for controlled proteolysis
    • Voges D, Zwickl P, Baumeister W. The 26S proteasome: a molecular machine designed for controlled proteolysis. Annu Rev Biochem. 1999;68:1015-1068.
    • (1999) Annu Rev Biochem , vol.68 , pp. 1015-1068
    • Voges, D.1    Zwickl, P.2    Baumeister, W.3
  • 75
    • 0030805622 scopus 로고    scopus 로고
    • A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease
    • Alam ZI, Daniel SE, Lees AJ, et al. A generalised increase in protein carbonyls in the brain in Parkinson's but not incidental Lewy body disease. J Neurochem. 1997;69:1326-1329.
    • (1997) J Neurochem , vol.69 , pp. 1326-1329
    • Alam, Z.I.1    Daniel, S.E.2    Lees, A.J.3
  • 76
    • 0035910634 scopus 로고    scopus 로고
    • Proteasomal function is impaired in substantia nigra in Parkinson's disease
    • McNaught KS, Jenner P. Proteasomal function is impaired in substantia nigra in Parkinson's disease. Neurosci Lett. 2001;297:191-194.
    • (2001) Neurosci Lett , vol.297 , pp. 191-194
    • McNaught, K.S.1    Jenner, P.2
  • 77
    • 0037227397 scopus 로고    scopus 로고
    • Altered proteasomal function in Parkinson's disease
    • McNaught KS, Belezaire R, lsacson O, et al. Altered proteasomal function in Parkinson's disease. Exp Neurol. 2003;179:38-46.
    • (2003) Exp Neurol , vol.179 , pp. 38-46
    • McNaught, K.S.1    Belezaire, R.2    Lsacson, O.3
  • 78
    • 0242531029 scopus 로고    scopus 로고
    • Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing parkin
    • Ardley HC, Scott GB, Rose SA, Tan NG, Markham AF, Robinson PA. Inhibition of proteasomal activity causes inclusion formation in neuronal and non-neuronal cells overexpressing parkin. Mol Biol Cell. 2003;14:4541-4556.
    • (2003) Mol Biol Cell , vol.14 , pp. 4541-4556
    • Ardley, H.C.1    Scott, G.B.2    Rose, S.A.3    Tan, N.G.4    Markham, A.F.5    Robinson, P.A.6
  • 79
    • 0242666359 scopus 로고    scopus 로고
    • Ubiquitination of α-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function
    • Tofaris GK, Razzaq A, Ghetti B, Lilley KS, Spillantini MG. Ubiquitination of α-synuclein in Lewy bodies is a pathological event not associated with impairment of proteasome function. J Biol Chem. 2003;278:44405-44411.
    • (2003) J Biol Chem , vol.278 , pp. 44405-44411
    • Tofaris, G.K.1    Razzaq, A.2    Ghetti, B.3    Lilley, K.S.4    Spillantini, M.G.5
  • 80
    • 0026662141 scopus 로고
    • Is the vulnerability of neurons in the substantia nigra of patients with Parkinson's disease related to their neuromelanin content?
    • Kastner A, Hirsch EC, Lejeune O, Javoy-Agid F, Rascol O, Agid Y. Is the vulnerability of neurons in the substantia nigra of patients with Parkinson's disease related to their neuromelanin content? J Neurochem. 1992;59:1080-1089.
    • (1992) J Neurochem , vol.59 , pp. 1080-1089
    • Kastner, A.1    Hirsch, E.C.2    Lejeune, O.3    Javoy-Agid, F.4    Rascol, O.5    Agid, Y.6
  • 82
    • 0031962268 scopus 로고    scopus 로고
    • Increased protein oxidation in human substantia nigra pars compacta in comparison with basal ganglia and prefrontal cortex measured with an improved dinitrophenylhydrazine assay
    • Floor E, Wetzel MG. Increased protein oxidation in human substantia nigra pars compacta in comparison with basal ganglia and prefrontal cortex measured with an improved dinitrophenylhydrazine assay. J Neurochem. 1998;70:268-275.
    • (1998) J Neurochem , vol.70 , pp. 268-275
    • Floor, E.1    Wetzel, M.G.2
  • 83
    • 0022415447 scopus 로고
    • Glutathione peroxidase activity in Parkinson's disease brain
    • Kish SJ, Morito C, Hornykiewicz O. Glutathione peroxidase activity in Parkinson's disease brain. Neurosci Lett. 1985;58:343-346.
    • (1985) Neurosci Lett , vol.58 , pp. 343-346
    • Kish, S.J.1    Morito, C.2    Hornykiewicz, O.3
  • 84
    • 0026635461 scopus 로고
    • Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease
    • The Royal Kings and Queens Parkinson's Disease Research Group
    • Jenner P, Dexter DT, Sian J, Schapira AH, Marsden CD. Oxidative stress as a cause of nigral cell death in Parkinson's disease and incidental Lewy body disease. The Royal Kings and Queens Parkinson's Disease Research Group. Ann Neurol. 1992;32(suppl):S82-S87.
    • (1992) Ann Neurol , vol.32 , Issue.SUPPL.
    • Jenner, P.1    Dexter, D.T.2    Sian, J.3    Schapira, A.H.4    Marsden, C.D.5
  • 86
    • 0024585155 scopus 로고
    • Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease
    • Dexter DT, Carter CJ, Wells FR, et al. Basal lipid peroxidation in substantia nigra is increased in Parkinson's disease. J Neurochem. 1989;52:381-389.
    • (1989) J Neurochem , vol.52 , pp. 381-389
    • Dexter, D.T.1    Carter, C.J.2    Wells, F.R.3
  • 87
    • 0032911488 scopus 로고    scopus 로고
    • Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons
    • Zhang J, Perry G, Smith MA, et al. Parkinson's disease is associated with oxidative damage to cytoplasmic DNA and RNA in substantia nigra neurons. Am J Pathol. 1999;154:1423-1429.
    • (1999) Am J Pathol , vol.154 , pp. 1423-1429
    • Zhang, J.1    Perry, G.2    Smith, M.A.3
  • 88
    • 0038236741 scopus 로고    scopus 로고
    • α-synuclein aggregation: A link between mitochondrial defects and Parkinson's disease?
    • Lee SJ. α-Synuclein aggregation: a link between mitochondrial defects and Parkinson's disease? Antioxid Redox Signal. 2003;5:337-348.
    • (2003) Antioxid Redox Signal , vol.5 , pp. 337-348
    • Lee, S.J.1
  • 89
    • 0030842085 scopus 로고    scopus 로고
    • Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with Parkinson disease
    • Hunot S, Brugg B, Ricard D, et al. Nuclear translocation of NF-kappaB is increased in dopaminergic neurons of patients with Parkinson disease. Proc Natl Acad Sci U S A. 1997;94:7531-7536.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 7531-7536
    • Hunot, S.1    Brugg, B.2    Ricard, D.3
  • 90
    • 0023804321 scopus 로고
    • Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain
    • Sofic E, Riederer P, Heinsen H, et al. Increased iron (III) and total iron content in post mortem substantia nigra of parkinsonian brain. J Neurol Transm. 1988;74:199-205.
    • (1988) J Neurol Transm , vol.74 , pp. 199-205
    • Sofic, E.1    Riederer, P.2    Heinsen, H.3
  • 91
    • 0026704075 scopus 로고
    • Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia
    • The Royal Kings and Queens Parkinson's Disease Research Group
    • Dexter DT, Jenner P, Schapira AH, Marsden CD. Alterations in levels of iron, ferritin, and other trace metals in neurodegenerative diseases affecting the basal ganglia. The Royal Kings and Queens Parkinson's Disease Research Group. Ann Neurol. 1992;32(suppl):S94-S100.
    • (1992) Ann Neurol , vol.32 , Issue.SUPPL.
    • Dexter, D.T.1    Jenner, P.2    Schapira, A.H.3    Marsden, C.D.4
  • 92
    • 0042433192 scopus 로고    scopus 로고
    • Neuromelanin associated redox-active iron is increased in the substantia nigra of patients with Parkinson's disease
    • Faucheux BA, Martin ME, Beaumont C, Hauw JJ, Agid Y, Hirsch EC. Neuromelanin associated redox-active iron is increased in the substantia nigra of patients with Parkinson's disease. J Neurochem. 2003;86:1142-1148.
    • (2003) J Neurochem , vol.86 , pp. 1142-1148
    • Faucheux, B.A.1    Martin, M.E.2    Beaumont, C.3    Hauw, J.J.4    Agid, Y.5    Hirsch, E.C.6
  • 93
    • 0041733066 scopus 로고    scopus 로고
    • Ironing out Parkinson's disease: Is therapeutic treatment with iron chelators a real possibility?
    • Kaur D, Andersen JK. Ironing out Parkinson's disease: is therapeutic treatment with iron chelators a real possibility? Aging Cell. 2002;1:17-21.
    • (2002) Aging Cell , vol.1 , pp. 17-21
    • Kaur, D.1    Andersen, J.K.2
  • 95
    • 0034602442 scopus 로고    scopus 로고
    • Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synudeinopathy lesions
    • Giasson BI, Duda JE, Murray IV, et al. Oxidative damage linked to neurodegeneration by selective α-synuclein nitration in synudeinopathy lesions. Science. 2000;290:985-989.
    • (2000) Science , vol.290 , pp. 985-989
    • Giasson, B.I.1    Duda, J.E.2    Murray, I.V.3
  • 96
    • 0031593604 scopus 로고    scopus 로고
    • Mechanisms of cell death in Alzheimer disease-immunopathology
    • McGeer PL, McGeer EG. Mechanisms of cell death in Alzheimer disease-immunopathology. J Neural Transm Suppl. 1998;54:159-166.
    • (1998) J Neural Transm Suppl , vol.54 , pp. 159-166
    • McGeer, P.L.1    McGeer, E.G.2
  • 97
    • 0242384667 scopus 로고    scopus 로고
    • Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine administration
    • McGeer PL, Schwab C, Parent A, Doudet D. Presence of reactive microglia in monkey substantia nigra years after 1-methyl-4-phenyl-1,2,3,6- tetrahydropyridine administration. Ann Neurol. 2003;54:599-604.
    • (2003) Ann Neurol , vol.54 , pp. 599-604
    • McGeer, P.L.1    Schwab, C.2    Parent, A.3    Doudet, D.4
  • 98
    • 0037378023 scopus 로고    scopus 로고
    • Neuroinflammatory processes in Parkinson's disease
    • Hunot S, Hirsch EC. Neuroinflammatory processes in Parkinson's disease. Ann Neurol. 2003;53(suppl 3):S49-S58.
    • (2003) Ann Neurol , vol.53 , Issue.SUPPL. 3
    • Hunot, S.1    Hirsch, E.C.2
  • 99
    • 0020680904 scopus 로고
    • Chronic parkinsonism in humans due to a product of meperidine-analog synthesis
    • Langston JW, Ballard P, Tetrud JW, Irwin I. Chronic parkinsonism in humans due to a product of meperidine-analog synthesis. Science. 1983;219:979-980.
    • (1983) Science , vol.219 , pp. 979-980
    • Langston, J.W.1    Ballard, P.2    Tetrud, J.W.3    Irwin, I.4
  • 100
    • 0032829070 scopus 로고    scopus 로고
    • Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure
    • Langston JW, Forno LS, Tetrud J, Reeves AG, Kaplan JA, Karluk D. Evidence of active nerve cell degeneration in the substantia nigra of humans years after 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine exposure. Ann Neurol. 1999;46:598-605.
    • (1999) Ann Neurol , vol.46 , pp. 598-605
    • Langston, J.W.1    Forno, L.S.2    Tetrud, J.3    Reeves, A.G.4    Kaplan, J.A.5    Karluk, D.6
  • 102
    • 0028364696 scopus 로고
    • Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease
    • Boka G, Anglade P, Wallach D, Javoy-Agid F, Agid Y, Hirsch EC. Immunocytochemical analysis of tumor necrosis factor and its receptors in Parkinson's disease. Neurosci Lett. 1994;172:151-154.
    • (1994) Neurosci Lett , vol.172 , pp. 151-154
    • Boka, G.1    Anglade, P.2    Wallach, D.3    Javoy-Agid, F.4    Agid, Y.5    Hirsch, E.C.6
  • 103
    • 0033121299 scopus 로고    scopus 로고
    • FcepsilonRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-α in glial cells
    • Hunot S, Dugas N, Faucheux B, et al. FcepsilonRII/CD23 is expressed in Parkinson's disease and induces, in vitro, production of nitric oxide and tumor necrosis factor-α in glial cells. J Neurosci. 1999;19:3440-3447.
    • (1999) J Neurosci , vol.19 , pp. 3440-3447
    • Hunot, S.1    Dugas, N.2    Faucheux, B.3
  • 104
    • 0343844458 scopus 로고    scopus 로고
    • Nitric oxide synthase and neuronal vulnerability in Parkinson's disease
    • Hunot S, Boissiere F, Faucheux B, et al. Nitric oxide synthase and neuronal vulnerability in Parkinson's disease. Neuroscience. 1996;72:355-363.
    • (1996) Neuroscience , vol.72 , pp. 355-363
    • Hunot, S.1    Boissiere, F.2    Faucheux, B.3
  • 105
    • 0023740773 scopus 로고
    • Rate of cell death in parkinsonism indicates active neuropathological process
    • McGeer PL, Itagaki S, Akiyama H, McGeer EG. Rate of cell death in parkinsonism indicates active neuropathological process. Ann Neurol. 1988;24:574-576.
    • (1988) Ann Neurol , vol.24 , pp. 574-576
    • McGeer, P.L.1    Itagaki, S.2    Akiyama, H.3    McGeer, E.G.4
  • 106
    • 0842299498 scopus 로고    scopus 로고
    • Microglial response is poorly correlated with neurodegeneration following chronic, low-dose MPTP administration in monkeys
    • Hurley SD, O'Banion MK, Song DD, Arana FS, Olschowka JA, Haber SN. Microglial response is poorly correlated with neurodegeneration following chronic, low-dose MPTP administration in monkeys. Exp Neurol. 2003;184:659-668.
    • (2003) Exp Neurol , vol.184 , pp. 659-668
    • Hurley, S.D.1    O'Banion, M.K.2    Song, D.D.3    Arana, F.S.4    Olschowka, J.A.5    Haber, S.N.6
  • 107
    • 2542455543 scopus 로고    scopus 로고
    • Evidence of active microglia in substantia nigra pars compacta of parkinsonian monkeys 1 year after MPTP exposure
    • Barcia C, Bahillo AS, Fernandez-Villaba E, et al. Evidence of active microglia in substantia nigra pars compacta of parkinsonian monkeys 1 year after MPTP exposure. Glia. 2004;46:402-409.
    • (2004) Glia , vol.46 , pp. 402-409
    • Barcia, C.1    Bahillo, A.S.2    Fernandez-Villaba, E.3
  • 108
    • 0037378897 scopus 로고    scopus 로고
    • Apoptosis in Parkinson's disease: Signals for neuronal degradation
    • Discussion. S70-S72
    • Tatton WG, Chalmers-Redman R, Brown D, Tatton N. Apoptosis in Parkinson's disease: signals for neuronal degradation. Ann Neurol. 2003;53(suppl 3):S61-S70. Discussion. S70-S72.
    • (2003) Ann Neurol , vol.53 , Issue.SUPPL. 3
    • Tatton, W.G.1    Chalmers-Redman, R.2    Brown, D.3    Tatton, N.4
  • 109
    • 0031738971 scopus 로고    scopus 로고
    • DNA fragmentation in human substantia nigra: Apoptosis or perimortem effect?
    • Kingsbury AE, Mardsen CD, Foster OJ. DNA fragmentation in human substantia nigra: apoptosis or perimortem effect? Mov Disord. 1998;13:877-884.
    • (1998) Mov Disord , vol.13 , pp. 877-884
    • Kingsbury, A.E.1    Mardsen, C.D.2    Foster, O.J.3
  • 110
    • 0032544268 scopus 로고    scopus 로고
    • Apoptotic pathways: The roads to ruin
    • Green DR. Apoptotic pathways: the roads to ruin. Cell. 1998;94:695-698.
    • (1998) Cell , vol.94 , pp. 695-698
    • Green, D.R.1
  • 111
    • 0036311251 scopus 로고    scopus 로고
    • Increased expression and redistribution of the antiapoptotic molecule Bcl-xL in Parkinson's disease
    • Hartmann A, Mouatt-Prigent A, Vila M, et al. Increased expression and redistribution of the antiapoptotic molecule Bcl-xL in Parkinson's disease. Neurobiol Dis. 2002;10:28-32.
    • (2002) Neurobiol Dis , vol.10 , pp. 28-32
    • Hartmann, A.1    Mouatt-Prigent, A.2    Vila, M.3
  • 112
    • 0035313071 scopus 로고    scopus 로고
    • Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis
    • Hartmann A, Troadec JD, Hunot S, et al. Caspase-8 is an effector in apoptotic death of dopaminergic neurons in Parkinson's disease, but pathway inhibition results in neuronal necrosis. J Neurosci. 2001;21:2247-2255.
    • (2001) J Neurosci , vol.21 , pp. 2247-2255
    • Hartmann, A.1    Troadec, J.D.2    Hunot, S.3
  • 113
    • 0035103294 scopus 로고    scopus 로고
    • Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease?
    • Hartmann A, Michel PP, Troadec JD, et al. Is Bax a mitochondrial mediator in apoptotic death of dopaminergic neurons in Parkinson's disease? J Neurochem. 2001;76:1785-1793.
    • (2001) J Neurochem , vol.76 , pp. 1785-1793
    • Hartmann, A.1    Michel, P.P.2    Troadec, J.D.3
  • 114
    • 0033756901 scopus 로고    scopus 로고
    • Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease
    • Tatton NA. Increased caspase 3 and Bax immunoreactivity accompany nuclear GAPDH translocation and neuronal apoptosis in Parkinson's disease. Exp Neurol. 2000;166:29-43.
    • (2000) Exp Neurol , vol.166 , pp. 29-43
    • Tatton, N.A.1
  • 115
  • 116
    • 0032879452 scopus 로고    scopus 로고
    • Role of cytochrome c as a stimulator of α-synuclein aggregation in Lewy body disease
    • Hashimoto M, Takeda A, Hsu LJ, Takenouchi T, Masliah E. Role of cytochrome c as a stimulator of α-synuclein aggregation in Lewy body disease. J Biol Chem. 1999;274:28849-28852.
    • (1999) J Biol Chem , vol.274 , pp. 28849-28852
    • Hashimoto, M.1    Takeda, A.2    Hsu, L.J.3    Takenouchi, T.4    Masliah, E.5
  • 118
    • 0042521076 scopus 로고    scopus 로고
    • The environment and Parkinson's disease: Is the nigrostriatal system preferentially targeted by neurotoxins?
    • Di Monte DA. The environment and Parkinson's disease: is the nigrostriatal system preferentially targeted by neurotoxins? Lancet Neurol. 2003;2:531-538.
    • (2003) Lancet Neurol , vol.2 , pp. 531-538
    • Di Monte, D.A.1
  • 121
    • 0032051813 scopus 로고    scopus 로고
    • Diorthosubstituted polychlorinated biphenyls in caudate nucleus in Parkinson's disease
    • Corrigan FM, Murray L, Wyatt CL, Shore RF. Diorthosubstituted polychlorinated biphenyls in caudate nucleus in Parkinson's disease. Exp Neurol. 1998;150:339-342.
    • (1998) Exp Neurol , vol.150 , pp. 339-342
    • Corrigan, F.M.1    Murray, L.2    Wyatt, C.L.3    Shore, R.F.4
  • 123
    • 0035816404 scopus 로고    scopus 로고
    • Pesticides directly accelerate the rate of a-synuclein fibril formation: A possible factor in Parkinson's disease
    • Uversky VN, Li J, Fink AL. Pesticides directly accelerate the rate of a-synuclein fibril formation: a possible factor in Parkinson's disease. FEBS Lett. 2001;500:105-108.
    • (2001) FEBS Lett , vol.500 , pp. 105-108
    • Uversky, V.N.1    Li, J.2    Fink, A.L.3
  • 124
    • 0035236558 scopus 로고    scopus 로고
    • A possible role of influenza A virus infection for Parkinson's disease
    • Takahashi M, Yamada T. A possible role of influenza A virus infection for Parkinson's disease. Adv Neurol. 2001;86:91-104.
    • (2001) Adv Neurol , vol.86 , pp. 91-104
    • Takahashi, M.1    Yamada, T.2
  • 125
    • 10744227580 scopus 로고    scopus 로고
    • In situ hybridization for detection of nocardial 16S rRNA: Reactivity within intracellular inclusions in experimentally infected cynomolgus monkeys-and in Lewy body-containing human brain specimens
    • Chapman G, Beaman BL, Loeffler DA, et al. In situ hybridization for detection of nocardial 16S rRNA: reactivity within intracellular inclusions in experimentally infected cynomolgus monkeys-and in Lewy body-containing human brain specimens. Exp Neurol. 2003;184:715-725.
    • (2003) Exp Neurol , vol.184 , pp. 715-725
    • Chapman, G.1    Beaman, B.L.2    Loeffler, D.A.3
  • 126
    • 0043207437 scopus 로고    scopus 로고
    • Neurovirological methods and their applications
    • Kennedy PG. Neurovirological methods and their applications. J Neurol Neurosurg Psychiatry. 2003;74:1016-1022.
    • (2003) J Neurol Neurosurg Psychiatry , vol.74 , pp. 1016-1022
    • Kennedy, P.G.1
  • 127
    • 0036171907 scopus 로고    scopus 로고
    • Parkinson's disease: The thalamic components of the limbic loop are severely impaired by α-synuclein immunopositive inclusion body pathology
    • Rub U, Del Tredici K, Schultz C, et al. Parkinson's disease: the thalamic components of the limbic loop are severely impaired by α-synuclein immunopositive inclusion body pathology. Neurobiol Aging. 2002;23:245-254.
    • (2002) Neurobiol Aging , vol.23 , pp. 245-254
    • Rub, U.1    Del Tredici, K.2    Schultz, C.3
  • 128
    • 0141725645 scopus 로고    scopus 로고
    • What causes mental dysfunction in Parkinson's disease?
    • Emre M. What causes mental dysfunction in Parkinson's disease? Mov Disord. 2003;18(suppl 6):S63-S71.
    • (2003) Mov Disord , vol.18 , Issue.SUPPL. 6
    • Emre, M.1
  • 129
    • 0030662269 scopus 로고    scopus 로고
    • Neuropathology of autonomie nervous system in Parkinson's disease
    • Wakabayashi K, Takahashi H. Neuropathology of autonomie nervous system in Parkinson's disease. Eur Neurol. 1997;38(suppl 2):2-7.
    • (1997) Eur Neurol , vol.38 , Issue.SUPPL. 2 , pp. 2-7
    • Wakabayashi, K.1    Takahashi, H.2
  • 130
    • 0038687021 scopus 로고    scopus 로고
    • Physiological and anatomical link between Parkinson-like disease and REM sleep behavior disorder
    • Lai YY, Siegel JM. Physiological and anatomical link between Parkinson-like disease and REM sleep behavior disorder. Mol Neurobiol. 2003;27:137-152.
    • (2003) Mol Neurobiol , vol.27 , pp. 137-152
    • Lai, Y.Y.1    Siegel, J.M.2
  • 131
    • 0038748401 scopus 로고    scopus 로고
    • Idiopathic Parkinson's disease: Possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen
    • Braak H, Rub U, Gai WP, Del Tredici K. Idiopathic Parkinson's disease: possible routes by which vulnerable neuronal types may be subject to neuroinvasion by an unknown pathogen. J Neural Transm. 2003;110:517-536.
    • (2003) J Neural Transm , vol.110 , pp. 517-536
    • Braak, H.1    Rub, U.2    Gai, W.P.3    Del Tredici, K.4
  • 135
    • 0041653249 scopus 로고    scopus 로고
    • Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease
    • Chen H, Zhang SM, Hernan MA, et al. Nonsteroidal anti-inflammatory drugs and the risk of Parkinson disease. Arch Neurol. 2003;60:1059-1064.
    • (2003) Arch Neurol , vol.60 , pp. 1059-1064
    • Chen, H.1    Zhang, S.M.2    Hernan, M.A.3
  • 136
    • 0041625716 scopus 로고    scopus 로고
    • Brain banking for neurodegenerative diseases
    • Murphy DD, Ravina B. Brain banking for neurodegenerative diseases. Curr Opin Neurol. 2003;16:459-463.
    • (2003) Curr Opin Neurol , vol.16 , pp. 459-463
    • Murphy, D.D.1    Ravina, B.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.