Vulnerability of midbrain dopaminergic neurons in calbindin-D28k-deficient mice: Lack of evidence for a neuroprotective role of endogenous calbindin in MPTP-treated and weaver mice

European Journal of Neuroscience

Volumn 9, Issue 1, 1997, Pages 120-127

  Meyer, Michael ^a  

^a MAX PLANCK INSTITUTE OF PSYCHIATRY   (Germany)

Author keywords

Calcium buffering; Calcium binding proteins; Calretinin; Neurotoxicity; Parkinson's disease; Tyrosine hydroxylase

Indexed keywords

1,2,3,6 TETRAHYDRO 1 METHYL 4 PHENYLPYRIDINE; CALBINDIN; CALCIUM BINDING PROTEIN; CALRETININ; TYROSINE 3 MONOOXYGENASE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CELL VIABILITY; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; FEMALE; GENE MUTATION; GENE TARGETING; MALE; MESENCEPHALON; MOUSE; NERVE DEGENERATION; NEUROPROTECTION; NEUROTOXICITY; NEWBORN; NONHUMAN; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN DEFICIENCY; PROTEIN EXPRESSION;

ANIMALS; CALCIUM-BINDING PROTEIN, VITAMIN D-DEPENDENT; CEREBELLAR ATAXIA; DOPAMINE; DOPAMINE AGENTS; FEMALE; IMMUNOHISTOCHEMISTRY; MESENCEPHALON; MICE; MICE, INBRED C57BL; MICE, INBRED CBA; MICE, NEUROLOGIC MUTANTS; MICROSCOPY, CONFOCAL; MPTP POISONING; NERVE TISSUE PROTEINS; NEURONS;

EID: 0031059220     PISSN: 0953816X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1460-9568.1997.tb01360.x     Document Type: Article

References (4)

1. Andressen, C, Blümcke, I. and Celio, M. R. (1993) Calcium-binding proteins: selective markers of nerve cells. Cell Tissue Res., 271, 181-208.
2. Baimbridge, K. G., Celio, M. R. and Rogers, J. H. (1992) Calcium binding proteins in the nervous system. Trends Neurosci., 15, 303-308.
3. Batini, C., Palestini, M., Thomasset, M. and Vigot, R. (1993) Cytoplasmic calcium buffer, calbindin-D28k, is regulated by excitatory amino acids. NeuroReport, 4, 927-930.
4. Blanchard, V., Raisman-Vozari, R., Vyas, S., Michel, P., Javoy-Agid, F., Uhl, G. and Agid, Y. (1994) Differential expression of tyrosine hydroxylase and membrane dopamine transporter genes in subpopulations of dopaminergic neurons of the rat mesencephalon. Mol. Brain Res., 22, 29-40.