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Volumn , Issue 16, 2008, Pages 2513-2517

Silver(I) versus gold(I) catalysis in benzannulation reaction: A versatile access to acridines

Author keywords

Acridine; Benzannulation; Gold; Quinoline; Silver

Indexed keywords

ACRIDINE DERIVATIVE; ALKYNE DERIVATIVE; GOLD; NAPHTHALENE; QUINOLINE; SILANE DERIVATIVE; SILVER;

EID: 54149118378     PISSN: 09365214     EISSN: None     Source Type: Journal    
DOI: 10.1055/s-2008-1078178     Document Type: Article
Times cited : (46)

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    • Typical Procedure: To a flask charged with silyl enol ether quinoline (0.1 mmol)44 dissolved in anhyd 1,2-dichloroethane (10 mL, was added silver catalyst (5 mol, The reaction mixture was stirred at 50°C until the reaction was judged complete by TLC analysis (0.5-2 h, The crude mixture was dissolved in CH2Cl2 and washed with a sat. aq solution of NaHCO3 (3 x, The organic phase was dried over Na2SO4, filtered and the solvents were removed in vacuo. If needed, the residue was loaded on a silica gel column and elution with the appropriate mixture of cyclohexane and EtOAc yielded the pure cyclised products. Selected spectroscopic data for entry 8, Table 3: isolated as a yellow oil (97, 1H NMR (300 MHz, CDCl3, 25°C, δ, 9.04 (s, 1 H, 8.20 (app d, 3JH,H, 8.8 Hz, 1 H, 8.02 (app d, 3JH,H, 8.3 Hz, 1 H, 7.77 s, 1 H
    • +: 443.2519; found: 443.2522.
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    • Silyl enol ether quinolines (Table 3) were prepared following a published procedure. Please see ref. 33.


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.