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Obtained following the same procedure as for 1 (Scheme 2) but starting with 4-amino-3-bromopyridine.
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65
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20444475521
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Prepared in 51% yield by treatment of 5c with BrCN in the presence of KH.
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In fact, electron-rich substrates, gave complex mixtures showing that, most likely, the cycloaddition is not regioselective.
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