Oleanolic acid derivative NPLC441 potently stimulates glucose transport in 3T3-L1 adipocytes via a multi-target mechanism

Biochemical Pharmacology

Volumn 76, Issue 10, 2008, Pages 1251-1262

  Lin, Zhonghui ^a   Zhang, Yu ^a   Zhang, Yinan ^a   Shen, Hong ^a   Hu, Lihong ^a   Jiang, Hualiang ^a   Shen, Xu ^a  

^a SHANGHAI INSTITUTE OF MATERIA MEDICA   (China)

Author keywords

11 HSD1; Antagonist; LXR :RXR ; Oleanolic acid; PTP1B; RXR

Indexed keywords

11BETA HYDROXYSTEROID DEHYDROGENASE; 3BETA (2 CARBOXYBENZOYLOXY)OLEANOLIC ACID; ANTIDIABETIC AGENT; GLUCOSE; GLUCOSE TRANSPORTER 4; INSULIN; LIVER X RECEPTOR ALPHA; NPLC 441; OLEANOLIC ACID DERIVATIVE; PROTEIN TYROSINE PHOSPHATASE 1B INHIBITOR; RETINOID X RECEPTOR ALPHA; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL STRAIN 3T3; CONTROLLED STUDY; DRUG MECHANISM; GLUCOSE TRANSPORT; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION;

3T3-L1 CELLS; ADIPOCYTES; ANIMALS; BIOLOGICAL TRANSPORT; CELL LINE; GLUCOSE; GLUCOSE TRANSPORT PROTEINS, FACILITATIVE; HUMANS; MICE; OLEANOLIC ACID; PROTEIN TYROSINE PHOSPHATASE, NON-RECEPTOR TYPE 1;

EID: 54049147673     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.08.016     Document Type: Article

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