Structural basis for inhibition of the protein tyrosine phosphatase 1B by phosphotyrosine peptide mimetics

Biochemistry

Volumn 37, Issue 51, 1998, Pages 17773-17783

  Groves, Matthew R ^a   Yao, Zhu Jun ^b   Roller, Peter P ^b   Burke Jr , Terrence R ^b   Barford, David ^a  

^a UNIVERSITY OF OXFORD   (United Kingdom)

^b NATIONAL CANCER INSTITUTE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PEPTIDE DERIVATIVE; PHOSPHOTYROSINE; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE INHIBITOR;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVE SITE; ENZYME CONFORMATION; ENZYME INHIBITOR INTERACTION; HUMAN; INHIBITION KINETICS; MOLECULAR INTERACTION; PRIORITY JOURNAL; STRUCTURE ACTIVITY RELATION;

BINDING SITES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; ENZYME INHIBITORS; HUMANS; MACROMOLECULAR SUBSTANCES; MODELS, MOLECULAR; MOLECULAR MIMICRY; ORGANOPHOSPHORUS COMPOUNDS; PEPTIDES, CYCLIC; PHOSPHONIC ACIDS; PHOSPHOTYROSINE; PROTEIN-TYROSINE-PHOSPHATASE; STRUCTURE-ACTIVITY RELATIONSHIP; TYROSINE;

EID: 0032559056     PISSN: 00062960     EISSN: None     Source Type: Journal    
DOI: 10.1021/bi9816958     Document Type: Article

References (39)

1. Neel, B. G., and Tonks, N. K. (1997) Curr. Opin. Cell Biol. 9, 193-204.
2. Denu, J. M., Stuckey, J. A., Saper, M. A., and Dixon, J. E. (1996) Cell 87, 361-364.
3. Fauman, E. B., and Saper, M. J. (1996) Trends Biochem. Sci. 21, 413-417.
4. Frangioni, J. V., Beahm, P. H., Shifrin, V., Jost, C. A., and Neel, B. G. (1992) Cell 68, 545-560.
5. Sugimoto, S., Wandless, T., Shoelson, S. E., Neel, B. G., and Walsh, C. T. (1994) J. Biol. Chem. 269, 13614-13622.
6. Barford, D., and Neel, B. G. (1998) Structure 6, 249-254.
7. Schultz, L. D., Schweitzer, P. A., Rajan, T. V., Yi, T., Ihle, J. N., Matthews, R. J., Thomas, M. L., and Beier, D. R. (1993) Cell 73, 1445-1454.
8. Li., J., Yen, C., Liaw, D., Podsypanina, K., Bose, S., Wang, S. I., Puc, J., Miliaresis, C., Rodgers, L., McCombie, R., Bigner, S. H., Giovanella, B. C., Ittmann, M., Tycko, B., Hibshoosh, H., Wigler, M. H., and Parsons, R. (1997) Science 275, 1943-1947
9. Steck, P. A., Pershouse, M. A., Jasser, S. A., Yung, W. K., Lin, H., Ligon, A. H., Langford, L. A., Baumgard, M. L., Hattier, T., Davies, T., Frye, C., Hu, R., Swedlund, B., Teng, D. H., and Tavtigian, S. V. (1997) Nat. Genet. 15, 356-362.
10. Tamura, M., Gu, J., Matsumoto, K., Aota, S., Parsons, R., and Yamada, K. M. (1998) Science 280, 1614-1617.
11. Seely, B. L., Staubs, P. A., Reichart, D. R., Berhanu, P., Milarski, K. L., Saltiel, A. R., Kusari, J., and Olefsky, J. M. (1996) Diabetes 45, 1479-1385.
12. Ahmad, F., Li, P. M., Meyerovitch, J., and Goldstein, B. J. (1995) J. Biol. Chem. 270, 20503-20508.
13. Burke, T. R., Jr., and Zhang, Z. Y. (1998) Pept. Sci. 47, 225-241.
14. Barford, D., Flint, A. J., and Tonks, N. K. (1994) Science 263, 1397-1404.
15. Jia, Z., Barford, D., Flint. A. J., and Tonks, N. K. (1995) Science 268, 1754-1758.
16. Burke, T. R., Jr., Kole H. K., and Roller, P. P. (1994) Biochem. Biophys. Res. Commun. 204, 129-134.
17. Kole, H. K., Smyth, M. S., Russ, P. L., and Burke, T. R., Jr. (1995) Biochem. J. 311, 1025-1031.
18. Burke, T. R., Ye, B., Yan, X., Wang, S., Jia, Z., Chen, L., Zhang, Z.-Y., and Barford, D. (1996) Biochemistry 35, 15989-15996.
19. Kole, H. K., Akamatsu, M., Ye, B., Yan, X., Barford, D., Roller, P. R., and Burke, T. R., Jr. (1995) Biochem. Biophys. Res. Commun. 209, 817-822.
20. Akamatsu, M., Roller, P. P., Chen, L., Zhang, Z. Y., Ye, B., and Burke, T. R., Jr. (1997) Bioorg. Med. Chem. 5, 157-163.
21. Burke, T. R., Jr., Ye, B., Akamatsu, M., Ford, H., Jr., Yan, X. Y., Kole, H., Wolf, G., Shoelson, S. E., and Roller, P. P. (1996) J. Med. Chem. 39, 1021-1027.
22. Roller, P. P., Wu, L., Zhang, Z.-Y., and Burke, T. R., Jr. (1998) Bioorg. Med. Chem. Lett. 8, 2149-2150.
23. Yao, Z. J., Ye, B., Wu, X. W., Wang, S., Wu, L., Zhang, Z. Y., and Burke, T. R., Jr. Bioorg. Med. Chem. (in press).
24. Barford, D., Keller, J. C., Flint, A. J., and Tonks, N. K. (1994) J. Mol. Biol. 239, 726-730.
25. Otwinoski, Z., and Minor, W. (1997) Processing X-ray diffraction data collected in oscillation mode, in Methods Enzymology (Carter, C., and Sweet, B., Eds.) Vol. 277, pp 307-326, Academic Press, New York.
26. Brunger, A. T. (1992) X-PLOR: version 3.1. Yale University Press, New Haven, CT.
27. Navaza, J. (1994) Acta Crystallogr., Sect. A 50, 157-160.
28. SYBYL 6.4 Tripos Inc., 1699 South Hanley Road, St. Louis, Missouri, 63144.
29. Jones, T. A., Zou, J. Y., Cowan, S. W., and Kjeldgaard, M. (1991) Acta Crystallogr., Sect. A 47, 110-119.
30. Lamzin, V. S., and Wilson, K. S. (1997) Methods Enzymology (Carter, C., and Sweet, B. Eds.) Vol. 277, pp 269-305, Academic Press, New York.
31. Murshudov, G. N., Vagin, A. A., and Dodson, E. J. (1997) Acta Crystallogr., Sect. D 53, 240-255.
32. Stuckey, J. A., Schubert, H. L., Fauman, E. B., Zhang, Z. Y., Dixon, J. E., and Saper, M. A. (1994) Nature 370, 571-575.
33. Schubert, H. L., Fauman, E. B., Stuckey, J. A., Dixon, J. E., and Saper, M. A. (1995) Protein Sci. 4, 1904-1913.
34. Maclean, D., Sefler, A. M., Zhu, G., Decker, S. J., Salteil, A. R., Singh, J., McNamara, D. M., Dobrusin, E. M., and Sawyer, T. K. (1995) Protein Sci. 4, 13-20.
35. Puius, Y. A., Zhao, Y., Sullivan, M., Lawrence, D. S., Almo, S. C., and Zhang, Z.-Y. (1997) Proc. Natl. Acad. Sci. U.S.A. 94, 13420-13425.
36. Zhang, Z. Y., Maclean, D., McNamara, D. J., Sawyer, T. K., and Dixon, J. E. (1994) Biochemistry 33, 2285-2290.
37. Burke, T. R., Jr., Yao, Z. J., Zhao, H., Milne, G. W. A., Wu, L., Zhang, Z.-Y., and Voigt, J. H. (1998) Tetrahedron 54, 9981-9994.
38. Kraulis, P. (1991) J. Appl. Crystallogr. 24, 946-950.
39. Diederichs, K., and Karplus, A. P. (1997) Nat. Struct. Biol. 4, 269-275.