The rexinoid LG100754 is a novel RXR:PPARγ agonist and decreases glucose levels in vivo

Molecular Endocrinology

Volumn 15, Issue 8, 2001, Pages 1360-1369

  Cesario, Rosemary M ^a   Klausing, Kay ^a   Razzaghi, Haleh ^a   Crombie, Diane ^a   Rungta, Deepa ^a   Heyman, Richard A ^a,c   Lala, Deepak S ^a,b  

^a LIGAND PHARMACEUTICALS INC   (United States)

^b PFIZER INC   (United States)

^c EXELIXIS INC   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

3 METHYL 7 (5,6,7,8 TETRAHYDRO 5,5,8,8 TETRAMETHYL 3 PROPOXY 2 NAPHTHYL) 2,4,6 OCTATRIENOIC ACID; 6 [1 (5,6,7,8 TETRAHYDRO 3,5,5,8,8 PENTAMETHYL 2 NAPHTHYL)CYCLOPROPYL]NICOTINIC ACID; DIMER; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR AGONIST; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR GAMMA; UNCLASSIFIED DRUG;

ADIPOCYTE; ANIMAL CELL; ARTICLE; CELL DIFFERENTIATION; CONTROLLED STUDY; DRUG MECHANISM; DRUG POTENCY; GLUCOSE BLOOD LEVEL; INHIBITION KINETICS; INSULIN RESISTANCE; INSULIN SENSITIVITY; MOUSE; NONHUMAN; PHOSPHORYLATION; PRIORITY JOURNAL; RECEPTOR UPREGULATION;

3T3 CELLS; ADIPOCYTES; ANIMALS; BLOOD GLUCOSE; CELL DIFFERENTIATION; DIABETES MELLITUS; DIMERIZATION; INSULIN RESISTANCE; MICE; NICOTINIC ACIDS; PHOSPHORYLATION; RECEPTOR, INSULIN; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, RETINOIC ACID; RETINOID X RECEPTORS; RETINOIDS; TETRAHYDRONAPHTHALENES; TRANSCRIPTION FACTORS; TUMOR NECROSIS FACTOR-ALPHA;

EID: 0034895388     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.15.8.1360     Document Type: Article

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