Oleanolic acid enhances insulin secretion in pancreatic β-cells

FEBS Letters

Volumn 582, Issue 9, 2008, Pages 1375-1380

  Teodoro, Tracy ^a,b   Zhang, Liling ^a   Alexander, Todd ^c   Yue, Jessica ^d   Vranic, Mladen ^d   Volchuk, Allen ^a,b,d  

^a UNIVERSITY HEALTH NETWORK   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c HOSPITAL FOR SICK CHILDREN   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Insulin biosynthesis; Insulin secretion; Oleanolic acid; Pancreatic beta cell

Indexed keywords

CALCIUM; CYCLIC AMP; EXENDIN 4; GLUCOSE; INCRETIN; INSULIN; OLEANOLIC ACID; OLEANOLIC ACID DERIVATIVE; TOLBUTAMIDE;

ANIMAL CELL; ARTICLE; CONTROLLED STUDY; DRUG EFFECT; DRUG MECHANISM; INSULIN RELEASE; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; RAT; STIMULUS RESPONSE;

ANIMALS; CALCIUM; CELL LINE; INSULIN; ISLETS OF LANGERHANS; MALE; OLEANOLIC ACID; RATS; RATS, WISTAR;

RATTUS;

EID: 41449083437     PISSN: 00145793     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.febslet.2008.03.026     Document Type: Article

References (20)

1. Cheng A.Y., and Fantus I.G. Oral antihyperglycemic therapy for type 2 diabetes mellitus. CMAJ 172 (2005) 213-226
2. Yeh G.Y., Kaptchuk T.J., Eisenberg D.M., and Phillips R.S. Systematic review of herbs and dietary supplements for glycemic control in diabetes. Diabetes Care 26 (2003) 1277-1294
3. Dzubak P., Hajduch M., Vydra D., Hustova A., Kvasnica M., Biedermann D., Markova L., Urban M., and Sarek J. Pharmacological activities of natural triterpenoids and their therapeutic implications. Nat. Prod. Rep. 23 (2006) 394-411
4. Liu J. Oleanolic and ursolic acid: research perspectives. J. Ethnopharm. 100 (2005) 92-94
5. Liby K.T., Yore M.M., and Sporn M.B. Triterpenoids and rexinoids as multifunctional agents for the prevention and treatment of cancer. Nat. Rev. Cancer 7 (2007) 357-369
6. Yoshikawa M., and Matsuda H. Antidiabetogenic activity of oleanolic acid glycosides from medicinal foodstuffs. BioFactors 13 (2000) 231-237
7. Hsu J.-H., Wu Y.-C., Liu I.-M., and Cheng J.-T. Release of acetylcholine to raise insulin secretion in Wistar rats by oleanolic acid one of the active principles contained in Cornus officinalis. Neurosci. Lett. 404 (2006) 112-116
8. Sato H., Genet C., Strehle A., Thomas C., Lobstein A., Wagner A., Mioskowski C., Auwerx J., and Saladin R. Anti-hyperglycemic activity of a TGR5 agonist isolated from Olea europaea. Biochem. Biophys. Res. Commun. 362 (2007) 793-798
9. Asfari M., Janjic D., Meda P., Li G., Halban P.A., and Wollheim C.B. Establishment of 2-mercaptoethanol-dependent differentiated insulin-secreting cell lines. Endocrinology 130 (1992) 167-178
10. + channel-dependent and -independent glucose-stimulated insulin secretion. Diabetes 49 (2000) 424-430
11. MacDonald P.E., Ha X.F., Wang J., Smukler S.R., Sun A.M., Gaisano H.Y., Salapatek A.M., Backx P.H., and Wheeler M.B. Members of the Kv1 and Kv2 voltage-dependent K(+) channel families regulate insulin secretion. Mol. Endocrinol. 15 (2001) 1423-1435
12. Bollheimer L.C., Skelly R.H., Chester M.W., McGarry J.D., and Rhodes C.J. Chronic exposure to free fatty acid reduces pancreatic beta-cell insulin content by increasing basal insulin secretion that is not compensated for by a corresponding increase in proinsulin biosynthesis translation. J. Clin. Invest. 101 (1998) 1094-1101
13. Karaskov E., Scott C., Zhang L., Teodoro T., Ravazzola M., and Volchuk A. Chronic palmitate but not oleate exposure induces endoplasmic reticulum stress, which may contribute to INS-1 pancreatic beta-cell apoptosis. Endocrinology 147 (2006) 3398-3407
14. 2+ microdomains and the control of insulin secretion. Cell Calcium 40 (2006) 539-551
15. Drucker D.J., and Nauck M.A. The incretin system: glucagon-like peptide-1 receptor agonists and dipeptidyl peptidase-4 inhibitors in type 2 diabetes. Lancet 368 (2006) 1696-1705
16. da Silva Xavier G., Leclerc I., Salt I.P., Doiron B., Haride D.G., Kahn A., and Rutter G.A. Role of AMP-activated protein kinase in the regulation by glucose of islet beta cell gene expression. Proc. Natl. Acad. Sci. USA 97 (2000) 4023-4028
17. Zhang Y., Jayaprakasam B., Seeram N.P., Olson L.K., DeWitt D., and Nair M.G. Insulin secretion and cyclooxygenase enzyme inhibition by Cabernet Sauvignon grape skin compounds. J. Agric. Food Chem. 52 (2004) 228-233
18. Jeong D.W., Kim Y.H., Kim H.H., Ji H.Y., Yoo S.D., Choi W.R., Lee S.M., Han C.K., and Lee H.S. Dose-linear pharmacokinetics of oleanolic acid after intravenous and oral administration in rats. Biopharm. Drug Dispos. 28 (2007) 51-57
19. Couch R.D., Browning R.G., Honda T., Gribble G.W., Wright D.L., Sporn M.B., and Anderson A.C. Studies on the reactivity of CDDO, a promising new chemopreventive and chemotherapeutic agent: implications for a molecular mechanism of action. Bioorg. Med. Chem. Lett. 15 (2005) 2215-2219
20. Ali M.S., Jahangir M., ul Hussan S.S., and Choudhary M.I. Inhibition of alpha-glucosidase by oleanolic acid and its synthetic derivatives. Phytochemistry 60 (2002) 295-299