A selective blocker of Kv1.2 and Kv1.3 potassium channels from the venom of the scorpion Centruroides suffusus suffusus

Biochemical Pharmacology

Volumn 76, Issue 9, 2008, Pages 1142-1154

  Corzo, Gerardo ^a   Papp, Ferenc ^b   Varga, Zoltan ^c   Barraza, Omar ^a   Espino Solis, Pavel G ^a   Rodríguez de la Vega, Ricardo C ^a   Gaspar, Rezso ^c   Panyi, Gyorgy ^c   Possani, Lourival D ^a  

^a INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

^b INSTITUTE OF EXPERIMENTAL MEDICINE   (Hungary)

^c UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Centruroides suffusus suffusus; K+ ion channel; Lymphocytes; Molecular modeling; Scorpion toxin

Indexed keywords

DISULFIDE; ION CHANNEL; PEPTIDE; PEPTIDE CSS20; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KV1.2; POTASSIUM CHANNEL KV1.3; SNAKE VENOM; TOXIN; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; CHEMICAL STRUCTURE; CONCENTRATION RESPONSE; HUMAN; HUMAN CELL; IC 50; MOLECULAR MODEL; MOLECULAR WEIGHT; NUCLEOTIDE SEQUENCE; POTASSIUM CURRENT; PRIORITY JOURNAL; SCORPION; SEQUENCE ANALYSIS; T LYMPHOCYTE;

AMINO ACID SEQUENCE; ANIMALS; CELL LINE, TUMOR; CELLS, CULTURED; CERCOPITHECUS AETHIOPS; COS CELLS; HUMANS; KV1.2 POTASSIUM CHANNEL; KV1.3 POTASSIUM CHANNEL; MICE; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; POTASSIUM CHANNEL BLOCKERS; RATS; SCORPION VENOMS; SCORPIONS;

EID: 53849098015     PISSN: 00062952     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bcp.2008.08.018     Document Type: Article

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