Evidence for domain-specific recognition of SK and Kv channels by MTX and HsTx1 scorpion toxins

Journal of Biological Chemistry

Volumn 279, Issue 53, 2004, Pages 55690-55696

  Regaya, Imed ^a   Beeton, Christine ^b   Ferrat, Gilles ^c   Andreotti, Nicolas ^a   Darbon, Hervé ^c   De Waard, Michel ^d   Sabatier, Jean Marc ^a,e  

^a CNRS   (France)

^b UNIVERSITY OF CALIFORNIA   (United States)

^c Centre National de la Recherche Scientifique   (France)

^d CEA GRENOBLE   (France)

^e Laboratoire Cellpep SA   (France)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; BIOCHEMISTRY; CROSSLINKING; PHARMACODYNAMICS; STRUCTURE (COMPOSITION); THREE DIMENSIONAL; TOXIC MATERIALS;

CHANNEL RECOGNITION; MAUROTOXIN (MTX); PEPTIDES; THREE-DIMENSIONAL STRUCTURE;

BIOLOGICAL MATERIALS;

CALCIUM ACTIVATED POTASSIUM CHANNEL; MAUROTOXIN; PROTEIN HSTX1; SCORPION VENOM; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; BETA SHEET; CARBOXY TERMINAL SEQUENCE; CHIMERA; CONTROLLED STUDY; CROSS LINKING; DISULFIDE BOND; EMBRYO; HUMAN; HUMAN CELL; MOUSE; NONHUMAN; POTASSIUM CONDUCTANCE; PRIORITY JOURNAL; PROTEIN FAMILY; PROTEIN FOLDING; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; SCORPION; STRUCTURE ANALYSIS; TOXIN STRUCTURE;

AMINO ACID SEQUENCE; ANIMALS; BINDING, COMPETITIVE; BRAIN; CELL LINE; DISULFIDES; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTROPHYSIOLOGY; ELECTROSTATICS; KV1.1 POTASSIUM CHANNEL; KV1.2 POTASSIUM CHANNEL; KV1.3 POTASSIUM CHANNEL; MAGNETIC RESONANCE SPECTROSCOPY; MICE; MOLECULAR SEQUENCE DATA; PEPTIDES; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; POTASSIUM CHANNELS, VOLTAGE-GATED; PROTEIN CONFORMATION; PROTEIN STRUCTURE, SECONDARY; PROTEIN STRUCTURE, TERTIARY; RATS; SCORPION VENOMS; SEQUENCE ANALYSIS, PROTEIN; SMALL-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; SYNAPTOSOMES; TIME FACTORS;

ANIMALIA; SCORPIONES;

EID: 11244306404     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M410055200     Document Type: Article

References (35)

1. Kharrat, R., Mansuelle, P., Sampieri, F., Crest, M., Oughideni, R., Van Rietschoten, J., Martin-Eauclaire, M. F., Rochat, H., and El Ayeb, M. (1997) FEBS Lett. 406, 284-290
2. Kharrat, R., Mabrouk, K., Crest, M., Darbon, H., Oughideni, R., Martin-Eauclaire, M. F., Jacquet, G., El Ayeb, M., Van Rietschoten, J., and Sabatier, J. M. (1996) Eur. J. Biochem. 242, 491-498
3. Olamendi-Portugal, T., Gomez-Lagunas, F., Gurrola, G. B., and Possani, L. (1996) Biochem. J. 315, 977-981
4. Olamendi-Portugal, T., Gomez-Lagunas, F., Gurrola, G. B., and Possani, L. D. (1998) Toxicon 36, 759-770
5. Lebrun, B., Romi-Lebrun, R., Martin-Eauclaire, M. F., Yasuda, A., Ishiguro, M., Oyama, Y., Pongs, O., and Nakajima, T. (1997) Biochem. J. 328, 321-327
6. Savarin, P., Romi-Lebrun, R., Zin-Justin, S., Lebrun, B., Nakajima, T., Gilquin, B., and Menez, A. (1999) Protein Sci. 8, 2672-2685
7. Tytgat, J., Chandy, G., Garcia, M. L., Gutman, G. A., Martin-Eauclaire, M-F., van der Walt, J. J., and Possani, L. D. (1999) Trends Physiol Sci. 20, 444-447
8. Castle, N. A., London, D. O., Creech, C., Fajloun, Z., Stocker, J. W., and Sabatier, J. M. (2003) Mol. Pharmacol. 63, 409-418
9. Carlier, E., Avdonin, V., Geib, S., Fajloun, Z., Kharrat, R., Rochat, H., Sabatier, J. M., Hoshi, T., and De Waard, M. (2000) J. Pept. Res. 55, 419-427
10. Avdonin, V., Nolan, B., Sabatier, J. M., De Waard, M., and Hoshi, T. (2000) Biophys. J. 79, 776-787
11. Fajloun, Z., Ferrat, G., Carlier, E., Fathallah, M., Lecomte, C., Sandoz, G., di Luccio, E., Mabrouk, K., Legros, C., Darbon, H., Rochat, H., Sabatier, J. M., and De Waard, M. (2000) J. Biol. Chem. 275, 13605-13612
12. M'Barek, S., Lopez-Gonzalez, I., Andreotti, N., di Luccio, E., Visan, V., Grissmer, S., Judge, S., El Ayeb, M., Darbon, H., Rochat, H., Sampieri, F., Beraud, E., Fajloun, Z., De Waard, M., and Sabatier, J.M. (2003) J. Biol. Chem. 278, 31095-31104
13. Blanc, E., Sabatier, J. M., Kharrat, R., Meunier, S., El Ayeb, M., Van Rietschoten, J., and Darbon, H. (1997) Proteins 29, 321-333
14. (12) Bontems, F., Roumestand, C., Gilquin, B., Ménez, A., and Toma, F. (1991) Science 254, 1521-1523
15. Mouhat, S., Jouirou, B., Mosbah, A., De Waard, M., and Sabatier, J. M. (2004) Biochem. J. 378, 717-726
16. Merrifield, R. B. (1986) Science 232, 341-347
17. Marion, D., and Wuthrich, K. (1983) Biochem. Biophys. Res. Commun. 113, 967-974
18. Piotto, M., Saudek, V., and Sklenar, V. (1992) J. Biomol. NMR 2, 661-665
19. Piantini, U., Sorensen, O. W., and Ernst, R. R. (1982) J. Am. Chem. Soc. 104, 6800-6801
20. Griesinger, C., Otting, G., Wüthrich, K., and Ernst, R. R. (1988) J. Am. Chem. Soc. 110, 7870-7872
21. Kumar, A., Ernst, R. R., and Wüthrich, K. (1981) Biochem. Biophys. Res. Comm. 95, 1-6
22. Bartels, C., Xia, T. H., Billeter, M., Güntert, P., and Wüthrich, K. (1995) J. Biomol. NMR 5, 1-10
23. Wüthrich, K. (1986) in NMR of Proteins and Nucleic Acids (Wüthrich, K., ed) pp. 117-176, John Wiley and Sons, New York
24. Güntert, P., Braun, W., and Wüthrich, K. (1991) J. Biomol. NMR 1, 111-130
25. Brunger, A. T., Adams, P. D., Clore, G. M., DeLano, W. L., Gros, P., Grosse-Kunstleve, R. W., Jiang, J. S., Kuszewski, J., Nilges, M., Pannu, N. S., Read, R. J., Rice, L. M., Simonson, T., and Warren, G. L. (1998) Acta Crystallogr. 54, 905-921
26. Roussel, A., and Cambillau, C. (1989) Silicon Graphics Geometry Partner Directory, pp. 77-78, Silicon Graphics, Mountain View, CA
27. Laskowski, R. A., Rullmannn, J. A., MacArthur, M. W., Kaptein, R., and Thornton, J. M. (1996) J. Biomol. NMR 8, 477-486
28. Nicholls, A., Sharp, K. A., and Honig, B. (1991) Proteins 11, 281-296
29. Nicholls, A., and Honig, B. (1991) J. Comput. Chem. 12, 435-445
30. Gray, E. G., and Whittaker, V. P. (1962) J. Anat. 96, 79-88
31. Grissmer, S., Nguyen, A. N., Aiyar, J., Hanson, D. C., Mather, R. J., Gutman, G. A., Karmilowicz, M. J., Auperin, A. A., and Chandy, K. G. (1994) Mol. Pharmacol. 45, 1227-1234
32. Darbon, H., Blanc, E., and Sabatier, J. M. (1999) in Perspectives in Drug Discovery and Design: Animal Toxins and Potassium Channels (Darbon, H., and Sabatier, J. M., eds) Vols. 15/16, pp. 41-60, Kluwer Academic Publishers, Dordrecht, The Netherlands
33. Fajloun, Z., Mosbah, H., Carlier, E., Mansuelle, P., Sandoz, G., Fathallah, M., di Luccio, E., Devaux, C., Rochat, H., Darbon, H., De Waard, M., and Sabatier, J. M. (2000) J. Biol. Chem. 275, 39394-39402
34. Sabatier, J. M., Fremont, V., Mabrouk, K., Crest, M., Darbon, H., Rochat, H., Van Rietschoten, J., and Martin-Eauclaire, M. F. (1994) Int. J. Peptide Protein Res. 43, 486-495
35. Sabatier, J. M., Zerrouk, H., Darbon, H., Mabrouk, K., Benslimane, A., Rochat, H., Martin-Eauclaire, M. F., and Van Rietschoten, J. (1993) Biochemistry 32, 2763-2770