Anuroctoxin, a new scorpion toxin of the α-KTx 6 subfamily, is highly selective for Kv1.3 over IKCa1 ion channels of human T lymphocytes

Molecular Pharmacology

Volumn 67, Issue 4, 2005, Pages 1034-1044

  Bagdány, Miklós ^a   Batista, Cesar V F ^b   Valdez Cruz, Norma A ^b   Somodi, Sándor ^a   Rodriguez De La Vega, Ricardo C ^b   Licea, Alexei F ^c   Varga, Zoltán ^a   Gáspár, Rezso ^a   Possani, Lourival D ^b   Panyi, György ^a  

^a UNIVERSITY OF DEBRECEN   (Hungary)

^b INSTITUTO DE BIOTECNOLOGÍA   (Mexico)

^c CENTRO DE INVESTIGACIÓN CIENTÍFICA Y DE EDUCACIÓN SUPERIOR DE ENSENADA   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ANUROCTOXIN; CALCIUM ACTIVATED POTASSIUM CHANNEL; POTASSIUM CHANNEL BLOCKING AGENT; POTASSIUM CHANNEL KV1.3; PYROGLUTAMIC ACID; SCORPION VENOM; UNCLASSIFIED DRUG; VOLTAGE GATED POTASSIUM CHANNEL; INTERMEDIATE CONDUCTANCE CALCIUM ACTIVATED POTASSIUM CHANNEL; KCNA3 PROTEIN, HUMAN; KCNN4 PROTEIN, HUMAN; TOXIN;

AMINO ACID SEQUENCE; ANUROCTONUS PHAIODACTYLUS; ARTICLE; AUTOIMMUNE DISEASE; CLUSTER ANALYSIS; CONTROLLED STUDY; COVALENT BOND; CYTOTOXIC T LYMPHOCYTE; DISULFIDE BOND; DRUG ISOLATION; DRUG STRUCTURE; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HUMAN; HUMAN CELL; MASS SPECTROMETRY; MOLECULAR WEIGHT; NONHUMAN; PATCH CLAMP; PHYLOGENY; POTASSIUM CHANNEL IKCA1; PRIORITY JOURNAL; SCORPION; T LYMPHOCYTE; T LYMPHOCYTE ACTIVATION; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG ANTAGONISM; DRUG EFFECT; ISOLATION AND PURIFICATION; SEQUENCE ALIGNMENT;

ANIMALS; HUMANS; INTERMEDIATE-CONDUCTANCE CALCIUM-ACTIVATED POTASSIUM CHANNELS; KV1.3 POTASSIUM CHANNEL; MODELS, MOLECULAR; PHYLOGENY; POTASSIUM CHANNEL BLOCKERS; POTASSIUM CHANNELS, CALCIUM-ACTIVATED; POTASSIUM CHANNELS, VOLTAGE-GATED; SCORPION VENOMS; SEQUENCE ALIGNMENT; T-LYMPHOCYTES; TOXINS, BIOLOGICAL;

EID: 20144386922     PISSN: 0026895X     EISSN: None     Source Type: Journal    
DOI: 10.1124/mol.104.007187     Document Type: Article

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