Docking study, synthesis, and in vitro evaluation of fluoro-MADAM derivatives as SERT ligands for PET imaging

Bioorganic and Medicinal Chemistry

Volumn 16, Issue 19, 2008, Pages 9050-9055

  Mavel, Sylvie ^a,b   Vercouillie, Johnny ^a,b   Garreau, Lucette ^a,b   Raguza, Tiziana ^a,b,c   Ravna, Aina Westrheim ^d   Chalon, Sylvie ^a,b   Guilloteau, Denis ^a,b,c   Emond, Patrick ^a,b  

^a Université de Tours   (France)

^b UNIVERSITÉ DE TOURS   (France)

^c CHU BRETONNEAU   (France)

^d UNIVERSITY OF TROMSØ   (Norway)

Author keywords

Diphenylsulfide derivatives; Molecular docking; SERT

Indexed keywords

CARBON 11; DIPHENYLSULFIDE DERIVATIVE; FLUORINE 18; RADIOLIGAND; SEROTONIN TRANSPORTER; SULFIDE; UNCLASSIFIED DRUG;

ARTICLE; BINDING AFFINITY; DRUG SELECTIVITY; DRUG SYNTHESIS; IN VITRO STUDY; ISOTOPE LABELING; LIGAND BINDING; MOLECULAR DOCKING; POSITRON EMISSION TOMOGRAPHY; REACTION ANALYSIS;

ALGORITHMS; BENZYLAMINES; CARBON RADIOISOTOPES; CELL LINE; DIAGNOSTIC IMAGING; FLUORINE RADIOISOTOPES; HUMANS; KIDNEY; LIGANDS; MEMBRANE TRANSPORT PROTEINS; POSITRON-EMISSION TOMOGRAPHY; REPRODUCIBILITY OF RESULTS; SENSITIVITY AND SPECIFICITY; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS;

EID: 52949104404     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2008.08.002     Document Type: Article

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