Putative drug binding conformations of monoamine transporters

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 3, 2006, Pages 666-675

  Ravna, Aina Westrheim ^a   Sylte, Ingebrigt ^a   Kristiansen, Kurt ^a   Dahl, Svein G ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

Author keywords

Cocaine; Molecular modeling; Monoamine transporters; S Citalopram

Indexed keywords

AMINO ACID DERIVATIVE; AMPHETAMINE; CARRIER PROTEIN; CITALOPRAM; COCAINE; DOPAMINE TRANSPORTER; LACTOSE PERMEASE; MONOAMINE TRANSPORTER; NORADRENALINE TRANSPOTER; SEROTONIN TRANSPORTER; SEROTONIN UPTAKE INHIBITOR; UNCLASSIFIED DRUG;

AMINO ACID SEQUENCE; ARTICLE; BINDING AFFINITY; BINDING SITE; CRYSTAL STRUCTURE; DRUG MECHANISM; DRUG PROTEIN BINDING; ENERGY; HYDROPHOBICITY; LIGAND BINDING; MOLECULAR MODEL; PROTEIN CONFORMATION;

AMINO ACID SEQUENCE; AMPHETAMINE; BINDING SITES; BIOGENIC MONOAMINES; CITALOPRAM; COCAINE; DOPAMINE PLASMA MEMBRANE TRANSPORT PROTEINS; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; NOREPINEPHRINE PLASMA MEMBRANE TRANSPORT PROTEINS; PROTEIN CONFORMATION; SEQUENCE HOMOLOGY, AMINO ACID; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SEROTONIN UPTAKE INHIBITORS; SYMPORTERS; THERMODYNAMICS;

EID: 28844506362     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.08.054     Document Type: Article

References (41)

1. K.A. Williams Nature 403 2000 112
2. A. Rothman, E. Padan, and S. Schuldiner J. Biol. Chem. 271 1996 32288
3. J. Reizer, A. Reizer, and M.H. Saier Jr. Biochim. Biophys. Acta 1197 1994 133
4. H.R. Kaback, and J.Q. Wu Rev. Biophys. 30 1997 333
5. F. Kilic, and G. Rudnick Proc. Natl. Acad. Sci. U.S.A. 97 2000 3106
6. A.S. Chang, D.M. Starnes, and S.M. Chang Biochem. Biophys. Res. Commun. 249 1998 416
7. H. Hastrup, A. Karlin, and J.A. Javitch Proc. Natl. Acad. Sci. U.S.A. 98 2001 10055 10060
8. G.E. Torres, A. Carneiro, K. Seamans, C. Fiorentini, A. Sweeney, W.D. Yao, and M.G. Caron J. Biol. Chem. 278 2003 2731
9. E.L. Barker, and R.D. Blakely Norepinephrine and Serotonin Transporters: Molecular Targets of Antidepressant Drugs F.E. Bloom D.J. Kupfer Psychopharmacology: The Fourth Generation of Progress 1995 Raven Press New York 321 334
10. J. Abramson, I. Smirnova, V. Kasho, G. Verner, H.R. Kaback, and S. Iwata Science 301 2003 610
11. Y. Huang, M.J. Lemieux, J. Song, M. Auer, and D.N. Wang Science 301 2003 616
12. A.W. Ravna, I. Sylte, and S.G. Dahl Receptors Channels 7 2001 319
13. A.W. Ravna, I. Sylte, and S.G. Dahl J. Comput. Aided Mol. Des. 17 2003 367
14. A.W. Ravna, I. Sylte, and S.G. Dahl J. Pharmacol. Exp. Ther. 307 2003 34
15. S.G. Dahl, I. Sylte, and A.W. Ravna J. Pharmacol. Exp. Ther. 309 2004 853
16. M. Tatsumi, K. Groshan, R.D. Blakely, and E. Richelson Eur. J. Pharmacol. 340 1997 249
17. M.F. Hibert, S. Trumpp-Kallmeyer, A. Bruinvels, and J. Hoflack Mol. Pharmacol. 40 1991 8
18. E. Pebay-Peyroula, G. Rummel, J.P. Rosenbusch, and E.M. Landau Science 277 1997 1676
19. G.V. Nikiforovich, S. Galaktionov, J. Balodis, and G.R. Marshall Acta Biochim. Pol. 48 2001 53
20. K. Palczewski, T. Kumasaka, T. Hori, C.A. Behnke, H. Motoshima, B.A. Fox, I. Le Trong, D.C. Teller, T. Okada, R.E. Stenkamp, M. Yamamoto, and M. Miyano Science 289 2000 739
21. N.A. Larsen, J.M. Turner, J. Stevens, S.J. Rosser, A. Basran, R.A. Lerner, N.C. Bruce, and I.A. Wilson Nat. Struct. Biol. 9 2002 17
22. A.S. Kristensen, M.B. Larsen, L.B. Johnsen, and O. Wiborg Eur. J. Neurosci. 19 2004 1513
23. C.A. Ilioudis, D.A. Tocher, and J.W. Steed J. Am. Chem. Soc. 126 2004 12395
24. E.L. Barker, M.A. Perlman, E.M. Adkins, W.J. Houlihan, Z.B. Pristupa, H.B. Niznik, and R.D. Blakely J. Biol. Chem. 273 1998 19459 19468
25. E.L. Barker, K.R. Moore, F. Rakhshan, and R.D. Blakely J. Neurosci. 19 1999 4705
26. S. Kitayama, S. Shimada, H. Xu, L. Markham, D.M. Donovan, and G.R. Uhl Proc. Natl. Acad. Sci. U.S.A. 89 1992 7782
27. S. Kitayama, K. Morita, T. Dohi, J.B. Wang, S.C. Davis, and G.R. Uhl Ann. N.Y. Acad. Sci. 801 1996 388
28. M.B. Larsen, B. Elfving, and O. Wiborg J. Biol. Chem. 279 2004 42147
29. R. Abagyan, M. Totrov, and D.N. Kuznetsov J. Comput. Chem. 15 1994 488
30. Case, D. A.; Darden, T. A.; Cheatham III, T. E.; Simmerling, C. L.; Wang, J.; Duke, R. E.; Luo, R.; Merz, K. M.; Wang, B.; Pearlman, D. A.; Crowley, M.; Brozell, S.; Tsui, V.; Gohlke, H.; Mongan, J.; Hornak, V.; Cui, G.; Beroza, P.; Schafmeister, C.; Caldwell, J. W.; Ross, W. S.; Kollman, P. A. AMBER 8; University of California: San Francisco, 2004.
31. K.P. Lesch, B.L. Wolozin, H.C. Estler, D.L. Murphy, and P. Riederer J. Neural. Transm. Gen. Sect. 91 1993 67
32. S. Ramamoorthy, A.L. Bauman, K.R. Moore, H. Han, T. Yang-Feng, A.S. Chang, V. Ganapathy, and R.D. Blakely Proc. Natl. Acad. Sci. U.S.A. 90 1993 2542
33. B. Giros, S. el Mestikawy, N. Godinot, K. Zheng, H. Han, T. Yang-Feng, and M.G. Caron Mol. Pharmacol. 42 1992 383
34. T. Pacholczyk, R.D. Blakely, and S.G. Amara Nature 350 1991 350
35. H.M. Berman, J. Westbrook, Z. Feng, G. Gilliland, T.N. Bhat, H. Weissig, I.N. Shindyalov, and P.E. Bourne Nucleic Acids Res. 28 2000 235
36. A.W. Ravna, and O. Edvardsen J. Mol. Graph. Model 20 2001 133
37. Z. Lin, W. Wang, T. Kopajtic, R.S. Revay, and G.R. Uhl Mol. Pharmacol. 56 1999 434
38. J.G. Chen, A. Sachpatzidis, and G. Rudnick J. Biol. Chem. 272 1997 28321
39. S.H. Lee, M.Y. Chang, K.H. Lee, B.S. Park, Y.S. Lee, and H.R. Chin Mol. Pharmacol. 57 2000 883
40. S. Kitayama, J.B. Wang, and G.R. Uhl Synapse 15 1993 58
41. C. Mitsuhata, S. Kitayama, K. Morita, D. Vandenbergh, G.R. Uhl, and T. Dohi Brain Res. Mol. Brain Res. 56 1998 84