New PET imaging agent for the serotonin transporter: [18F]ACF (2-[(2-amino-4-chloro-5-fluorophenyl)thio]-N,N-dimethyl-benzenmethanamine)

Journal of Medicinal Chemistry

Volumn 45, Issue 21, 2002, Pages 4716-4723

  Oya, Shunichi ^a   Choi, Seok Rye ^a   Coenen, Heinz ^b   Kung, Hank F ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b FORSCHUNGSZENTRUM JÜLICH   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

1,2,3,5,6,10B HEXAHYDRO 6 (4 METHYLTHIOPHENYL)PYRROLO[2,1 A]ISOQUINOLINE; 2 [(2 AMINO 4 CHLORO 5 FLUOROPHENYL)THIO] N,N DIMETHYLBENZENMETHANAMINE; 2 MERCAPTO N,N DIMETHYLBENZAMIDE; 2,5 DICHLORO 4 NITROANILINE; ANILINE DERIVATIVE; BENZAMIDE DERIVATIVE; BORANE DERIVATIVE; DOPAMINE TRANSPORTER; FLUORINE 18; METHYLPHENIDATE; NISOXETINE; NORADRENALIN TRANSPORTER; PHENYLTHIOPHENYL DERIVATIVE; POTASSIUM CARBONATE; RADIOPHARMACEUTICAL AGENT; SEROTONIN TRANSPORTER; TETRAHYDROFURAN; TRIMETHYLAMMONIUM SALT DERIVATIVE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CEREBELLUM; CONTROLLED STUDY; DRUG PURITY; DRUG STRUCTURE; DRUG SYNTHESIS; DRUG UPTAKE; HYPOTHALAMUS; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; RAT; REACTION ANALYSIS;

ANIMALS; BENZYLAMINES; BINDING, COMPETITIVE; BRAIN; CARRIER PROTEINS; CELL LINE; FLUORINE RADIOISOTOPES; MEMBRANE GLYCOPROTEINS; MEMBRANE TRANSPORT PROTEINS; NERVE TISSUE PROTEINS; RADIOPHARMACEUTICALS; RATS; SEROTONIN; SEROTONIN PLASMA MEMBRANE TRANSPORT PROTEINS; SULFIDES; TISSUE DISTRIBUTION; TOMOGRAPHY, EMISSION-COMPUTED;

EID: 0037057546     PISSN: 00222623     EISSN: None     Source Type: Journal    
DOI: 10.1021/jm020167y     Document Type: Article

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