-
1
-
-
33748612442
-
NK cell function in HIV-1 infection
-
10.2174/156652406778195035. 17022732
-
NK cell function in HIV-1 infection. G Alter M Altfeld, Curr Mol Med 2006 6 621 629 10.2174/156652406778195035 17022732
-
(2006)
Curr Mol Med
, vol.6
, pp. 621-629
-
-
Alter, G.1
Altfeld, M.2
-
2
-
-
4344569076
-
The role of CD8+ T-cell response in HIV infection
-
15332430
-
The role of CD8+ T-cell response in HIV infection. JM Benito M Lopez V Soriano, AIDS Rev 2004 6 79 88 15332430
-
(2004)
AIDS Rev
, vol.6
, pp. 79-88
-
-
Benito, J.M.1
Lopez, M.2
Soriano, V.3
-
3
-
-
0842336368
-
T cell immunity to HIV: Defining parameters of protection
-
10.2174/1570162033485294. 15043207
-
T cell immunity to HIV: defining parameters of protection. HT Maecker VC Maino, Curr HIV Res 2003 1 249 259 10.2174/1570162033485294 15043207
-
(2003)
Curr HIV Res
, vol.1
, pp. 249-259
-
-
Maecker, H.T.1
Maino, V.C.2
-
4
-
-
0028145416
-
Virus escape from CTL recognition
-
7520471. 10.1084/jem.180.3.779
-
Virus escape from CTL recognition. RA Koup, J Exp Med 1994 180 779 782 7520471 10.1084/jem.180.3.779
-
(1994)
J Exp Med
, vol.180
, pp. 779-782
-
-
Koup, R.A.1
-
5
-
-
7144227284
-
Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA
-
10.1126/science.279.5359.2103. 9516110
-
Quantitation of HIV-1-specific cytotoxic T lymphocytes and plasma load of viral RNA. GS Ogg X Jin S Bonhoeffer PR Dunbar MA Nowak S Monard JP Segal Y Cao SL Rowland-Jones V Cerundolo, Science 1998 279 2103 2106 10.1126/science.279. 5359.2103 9516110
-
(1998)
Science
, vol.279
, pp. 2103-2106
-
-
Ogg, G.S.1
Jin, X.2
Bonhoeffer, S.3
Dunbar, P.R.4
Nowak, M.A.5
Monard, S.6
Segal, J.P.7
Cao, Y.8
Rowland-Jones, S.L.9
Cerundolo, V.10
-
6
-
-
0028041344
-
Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection
-
8057491
-
Virus-specific CD8+ cytotoxic T-lymphocyte activity associated with control of viremia in primary human immunodeficiency virus type 1 infection. P Borrow H Lewicki BH Hahn GM Shaw MB Oldstone, J Virol 1994 68 6103 6110 8057491
-
(1994)
J Virol
, vol.68
, pp. 6103-6110
-
-
Borrow, P.1
Lewicki, H.2
Hahn, B.H.3
Shaw, G.M.4
Oldstone, M.B.5
-
7
-
-
3042545965
-
Cytotoxic T lymphocyte-based control of simian immunodeficiency virus replication in a preclinical AIDS vaccine trial
-
15210746. 10.1084/jem.20040432
-
Cytotoxic T lymphocyte-based control of simian immunodeficiency virus replication in a preclinical AIDS vaccine trial. T Matano M Kobayashi H Igarashi A Takeda H Nakamura M Kano C Sugimoto K Mori A Iida T Hirata, J Exp Med 2004 199 1709 1718 15210746 10.1084/jem.20040432
-
(2004)
J Exp Med
, vol.199
, pp. 1709-1718
-
-
Matano, T.1
Kobayashi, M.2
Igarashi, H.3
Takeda, A.4
Nakamura, H.5
Kano, M.6
Sugimoto, C.7
Mori, K.8
Iida, A.9
Hirata, T.10
-
8
-
-
0035667633
-
Understanding cytotoxic T-lymphocyte escape during simian immunodeficiency virus infection
-
10.1034/j.1600-065x.2001.1830110.x. 11782252
-
Understanding cytotoxic T-lymphocyte escape during simian immunodeficiency virus infection. D O'Connor T Friedrich A Hughes TM Allen D Watkins, Immunol Rev 2001 183 115 126 10.1034/j.1600-065x.2001.1830110.x 11782252
-
(2001)
Immunol Rev
, vol.183
, pp. 115-126
-
-
O'Connor, D.1
Friedrich, T.2
Hughes, A.3
Allen, T.M.4
Watkins, D.5
-
9
-
-
0034699512
-
Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia
-
10.1038/35036559. 11014195
-
Tat-specific cytotoxic T lymphocytes select for SIV escape variants during resolution of primary viraemia. TM Allen DH O'Connor P Jing JL Dzuris BR Mothe TU Vogel E Dunphy ME Liebl C Emerson N Wilson, Nature 2000 407 386 390 10.1038/35036559 11014195
-
(2000)
Nature
, vol.407
, pp. 386-390
-
-
Allen, T.M.1
O'Connor, D.H.2
Jing, P.3
Dzuris, J.L.4
Mothe, B.R.5
Vogel, T.U.6
Dunphy, E.7
Liebl, M.E.8
Emerson, C.9
Wilson, N.10
-
10
-
-
3543078012
-
HIV and SIV CTL escape: Implications for vaccine design
-
10.1038/nri1417. 15286729
-
HIV and SIV CTL escape: implications for vaccine design. PJ Goulder DI Watkins, Nat Rev Immunol 2004 4 630 640 10.1038/nri1417 15286729
-
(2004)
Nat Rev Immunol
, vol.4
, pp. 630-640
-
-
Goulder, P.J.1
Watkins, D.I.2
-
11
-
-
33846111016
-
Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants
-
10.1038/nm1461. 17187074
-
Polyvalent vaccines for optimal coverage of potential T-cell epitopes in global HIV-1 variants. W Fischer S Perkins J Theiler T Bhattacharya K Yusim R Funkhouser C Kuiken B Haynes NL Letvin BD Walker, Nat Med 2007 13 100 106 10.1038/nm1461 17187074
-
(2007)
Nat Med
, vol.13
, pp. 100-106
-
-
Fischer, W.1
Perkins, S.2
Theiler, J.3
Bhattacharya, T.4
Yusim, K.5
Funkhouser, R.6
Kuiken, C.7
Haynes, B.8
Letvin, N.L.9
Walker, B.D.10
-
12
-
-
0004040198
-
-
Los Alamos National Laboratory, Los Alamos, NM
-
BTM Korber C Brander BF Hayens R Koup JP Moore BD Walker DI Watkins, HIV Molecular Immunology Los Alamos National Laboratory, Los Alamos, NM 2007
-
(2007)
HIV Molecular Immunology
-
-
Korber, B.T.M.1
Brander, C.2
Hayens, B.F.3
Koup, R.4
Moore, J.P.5
Walker, B.D.6
Watkins, D.I.7
-
13
-
-
0035525978
-
HIV-1 replication
-
10.1023/A:1021070512287. 12465460
-
HIV-1 replication. EO Freed, Somat Cell Mol Genet 2001 26 13 33 10.1023/A:1021070512287 12465460
-
(2001)
Somat Cell Mol Genet
, vol.26
, pp. 13-33
-
-
Freed, E.O.1
-
14
-
-
0000829669
-
HIVs and their replication
-
Lippincott Williams & Wilkins, Philadelphia Knipe DM, Howley PM
-
HIVs and their replication. EO Freed MA Martin, "Fields' Virology" Lippincott Williams & Wilkins, Philadelphia, Knipe DM, Howley PM, 2001 1971 2041
-
(2001)
"fields' Virology"
, pp. 1971-2041
-
-
Freed, E.O.1
Martin, M.A.2
-
15
-
-
0037043699
-
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein
-
10.1038/nature00939. 12167863
-
Isolation of a human gene that inhibits HIV-1 infection and is suppressed by the viral Vif protein. AM Sheehy NC Gaddis JD Choi MH Malim, Nature 2002 418 646 650 10.1038/nature00939 12167863
-
(2002)
Nature
, vol.418
, pp. 646-650
-
-
Sheehy, A.M.1
Gaddis, N.C.2
Choi, J.D.3
Malim, M.H.4
-
16
-
-
0038004471
-
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA
-
12808465. 10.1038/nature01707
-
The cytidine deaminase CEM15 induces hypermutation in newly synthesized HIV-1 DNA. H Zhang B Yang RJ Pomerantz C Zhang SC Arunachalam L Gao, Nature 2003 424 94 98 12808465 10.1038/nature01707
-
(2003)
Nature
, vol.424
, pp. 94-98
-
-
Zhang, H.1
Yang, B.2
Pomerantz, R.J.3
Zhang, C.4
Arunachalam, S.C.5
Gao, L.6
-
17
-
-
2342637186
-
HIV-1 Vpr: Genetic diversity and functional features from the perspective of structure
-
10.1089/104454904773819798. 15142378
-
HIV-1 Vpr: genetic diversity and functional features from the perspective of structure. PK Tungaturthi BE Sawaya V Ayyavoo R Murali A Srinivasan, DNA Cell Biol 2004 23 207 222 10.1089/104454904773819798 15142378
-
(2004)
DNA Cell Biol
, vol.23
, pp. 207-222
-
-
Tungaturthi, P.K.1
Sawaya, B.E.2
Ayyavoo, V.3
Murali, R.4
Srinivasan, A.5
-
18
-
-
0344303622
-
Viral protein U counteracts a human host cell restriction that inhibits HIV-1 particle production
-
14657387. 10.1073/pnas.2433165100
-
Viral protein U counteracts a human host cell restriction that inhibits HIV-1 particle production. V Varthakavi RM Smith SP Bour K Strebel P Spearman, Proc Natl Acad Sci USA 2003 100 15154 15159 14657387 10.1073/pnas.2433165100
-
(2003)
Proc Natl Acad Sci USA
, vol.100
, pp. 15154-15159
-
-
Varthakavi, V.1
Smith, R.M.2
Bour, S.P.3
Strebel, K.4
Spearman, P.5
-
19
-
-
0026452726
-
Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4
-
1433512
-
Human immunodeficiency virus type 1 Vpu protein induces rapid degradation of CD4. RL Willey F Maldarelli MA Martin K Strebel, J Virol 1992 66 7193 7200 1433512
-
(1992)
J Virol
, vol.66
, pp. 7193-7200
-
-
Willey, R.L.1
Maldarelli, F.2
Martin, M.A.3
Strebel, K.4
-
20
-
-
1542317632
-
Extracellular Nef protein targets CD4+ T cells for apoptosis by interacting with CXCR4 surface receptors
-
14990729. 10.1128/JVI.78.6.3099-3109.2004
-
Extracellular Nef protein targets CD4+ T cells for apoptosis by interacting with CXCR4 surface receptors. CO James MB Huang M Khan M Garcia-Barrio MD Powell VC Bond, J Virol 2004 78 3099 3109 14990729 10.1128/JVI.78.6.3099-3109.2004
-
(2004)
J Virol
, vol.78
, pp. 3099-3109
-
-
James, C.O.1
Huang, M.B.2
Khan, M.3
Garcia-Barrio, M.4
Powell, M.D.5
Bond, V.C.6
-
21
-
-
0035368515
-
Dynamic Nef and Nef dynamics: How structure could explain the complex activities of this small HIV protein
-
10.1016/S0968-0004(01)01846-1. 11406408
-
Dynamic Nef and Nef dynamics: how structure could explain the complex activities of this small HIV protein. ST Arold AS Baur, Trends Biochem Sci 2001 26 356 363 10.1016/S0968-0004(01)01846-1 11406408
-
(2001)
Trends Biochem Sci
, vol.26
, pp. 356-363
-
-
Arold, S.T.1
Baur, A.S.2
-
22
-
-
0035848864
-
HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell
-
10.1038/35071111. 11298454
-
HIV-1 Nef inhibits ASK1-dependent death signalling providing a potential mechanism for protecting the infected host cell. R Geleziunas W Xu K Takeda H Ichijo WC Greene, Nature 2001 410 834 838 10.1038/35071111 11298454
-
(2001)
Nature
, vol.410
, pp. 834-838
-
-
Geleziunas, R.1
Xu, W.2
Takeda, K.3
Ichijo, H.4
Greene, W.C.5
-
23
-
-
0030768607
-
HIV-1 Nef protein-induced apoptotic cytolysis of a broad spectrum of uninfected human blood cells independently of CD95(Fas)
-
10.1016/S0014-5793(97)01080-6. 9323045
-
HIV-1 Nef protein-induced apoptotic cytolysis of a broad spectrum of uninfected human blood cells independently of CD95(Fas). H Okada R Takei M Tashiro, FEBS Lett 1997 414 603 606 10.1016/S0014-5793(97)01080-6 9323045
-
(1997)
FEBS Lett
, vol.414
, pp. 603-606
-
-
Okada, H.1
Takei, R.2
Tashiro, M.3
-
24
-
-
18844363668
-
Biology of the HIV Nef protein
-
15817946
-
Biology of the HIV Nef protein. SR Das S Jameel, Indian J Med Res 2005 121 315 332 15817946
-
(2005)
Indian J Med Res
, vol.121
, pp. 315-332
-
-
Das, S.R.1
Jameel, S.2
-
25
-
-
0001877356
-
Pathogenesis and medical aspects of HIV-1 infection
-
Lippincott Williams & Wilkins, Philadelphia
-
Pathogenesis and medical aspects of HIV-1 infection. OJ Cohen AS Fauci, "Fields' Virology" Lippincott Williams & Wilkins, Philadelphia 2001 2043 2094
-
(2001)
"fields' Virology"
, pp. 2043-2094
-
-
Cohen, O.J.1
Fauci, A.S.2
-
27
-
-
33846817305
-
Identification of HLA class I-associated amino acid polymorphisms in the HIV-1C proteome
-
10.1089/aid.2006.0131. 17263647
-
Identification of HLA class I-associated amino acid polymorphisms in the HIV-1C proteome. CL Boutwell M Essex, AIDS Res Hum Retroviruses 2007 23 165 174 10.1089/aid.2006.0131 17263647
-
(2007)
AIDS Res Hum Retroviruses
, vol.23
, pp. 165-174
-
-
Boutwell, C.L.1
Essex, M.2
-
28
-
-
0036340475
-
Clustering patterns of cytotoxic T-lymphocyte epitopes in human immunodeficiency virus type 1 (HIV-1) proteins reveal imprints of immune evasion on HIV-1 global variation
-
12163596. 10.1128/JVI.76.17.8757-8768.2002
-
Clustering patterns of cytotoxic T-lymphocyte epitopes in human immunodeficiency virus type 1 (HIV-1) proteins reveal imprints of immune evasion on HIV-1 global variation. K Yusim C Kesmir B Gaschen MM Addo M Altfeld S Brunak A Chigaev V Detours BT Korber, J Virol 2002 76 8757 8768 12163596 10.1128/JVI.76.17.8757-8768.2002
-
(2002)
J Virol
, vol.76
, pp. 8757-8768
-
-
Yusim, K.1
Kesmir, C.2
Gaschen, B.3
Addo, M.M.4
Altfeld, M.5
Brunak, S.6
Chigaev, A.7
Detours, V.8
Korber, B.T.9
-
29
-
-
33746150392
-
Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes
-
10.1016/j.jviromet.2006.04.009. 16701907
-
Large-scale amplification, cloning and sequencing of near full-length HIV-1 subtype C genomes. CM Rousseau BA Birditt AR McKay JN Stoddard TC Lee S McLaughlin SW Moore N Shindo GH Learn BT Korber, J Virol Methods 2006 136 118 125 10.1016/j.jviromet.2006.04.009 16701907
-
(2006)
J Virol Methods
, vol.136
, pp. 118-125
-
-
Rousseau, C.M.1
Birditt, B.A.2
McKay, A.R.3
Stoddard, J.N.4
Lee, T.C.5
McLaughlin, S.6
Moore, S.W.7
Shindo, N.8
Learn, G.H.9
Korber, B.T.10
-
30
-
-
45749104088
-
HLA Class-I Driven Evolution of Human Immunodeficiency Virus Type 1 Subtype C Proteome: Immune Escape and Viral Load
-
18434400. 10.1128/JVI.02455-07
-
HLA Class-I Driven Evolution of Human Immunodeficiency Virus Type 1 Subtype C Proteome: Immune Escape and Viral Load. CM Rousseau MG Daniels JM Carlson C Kadie H Crawford A Prendergast P Matthews R Payne M Rolland DN Raugi, J Virol 2008 82 6434 46 18434400 10.1128/JVI.02455-07
-
(2008)
J Virol
, vol.82
, pp. 6434-46
-
-
Rousseau, C.M.1
Daniels, M.G.2
Carlson, J.M.3
Kadie, C.4
Crawford, H.5
Prendergast, A.6
Matthews, P.7
Payne, R.8
Rolland, M.9
Raugi, D.N.10
-
31
-
-
0034719429
-
Could Nef and Vpr proteins contribute to disease progression by promoting depletion of bystander cells and prolonged survival of HIV-infected cells?
-
10.1006/bbrc.1999.1708. 10673351
-
Could Nef and Vpr proteins contribute to disease progression by promoting depletion of bystander cells and prolonged survival of HIV-infected cells? AA Azad, Biochem Biophys Res Commun 2000 267 677 685 10.1006/bbrc.1999.1708 10673351
-
(2000)
Biochem Biophys Res Commun
, vol.267
, pp. 677-685
-
-
Azad, A.A.1
-
32
-
-
0030250588
-
HIV-1, Vpr and the cell cycle
-
10.1016/S0960-9822(02)00676-0. 8805364
-
HIV-1, Vpr and the cell cycle. M Emerman, Curr Biol 1996 6 1096 1103 10.1016/S0960-9822(02)00676-0 8805364
-
(1996)
Curr Biol
, vol.6
, pp. 1096-1103
-
-
Emerman, M.1
-
33
-
-
0033056877
-
Viral protein R of HIV-1
-
10.1002/(SICI)1099-1654(199901/03)9:1〈39::AID-RMV235〉3.0. CO;2-3. 10371671
-
Viral protein R of HIV-1. M Bukrinsky A Adzhubei, Rev Med Virol 1999 9 39 49 10.1002/(SICI)1099-1654(199901/03)9:1〈39::AID-RMV235〉3.0.CO;2-3 10371671
-
(1999)
Rev Med Virol
, vol.9
, pp. 39-49
-
-
Bukrinsky, M.1
Adzhubei, A.2
-
34
-
-
0032546817
-
HIV-1 regulatory/accessory genes: Keys to unraveling viral and host cell biology
-
10.1126/science.280.5371.1880. 9632380
-
HIV-1 regulatory/accessory genes: keys to unraveling viral and host cell biology. M Emerman MH Malim, Science 1998 280 1880 1884 10.1126/science.280. 5371.1880 9632380
-
(1998)
Science
, vol.280
, pp. 1880-1884
-
-
Emerman, M.1
Malim, M.H.2
-
35
-
-
33947225784
-
Near full-length genome characterization of three additional HIV type 1 CRF13_cpx strains from Cameroon
-
10.1089/aid.2006.0177. 17331036
-
Near full-length genome characterization of three additional HIV type 1 CRF13_cpx strains from Cameroon. KC Luk V Holzmayer J Yamaguchi P Swanson CA Brennan C Ngansop D Mbanya H Gayum MN Djuidje N Ndembi, AIDS Res Hum Retroviruses 2007 23 297 302 10.1089/aid.2006.0177 17331036
-
(2007)
AIDS Res Hum Retroviruses
, vol.23
, pp. 297-302
-
-
Luk, K.C.1
Holzmayer, V.2
Yamaguchi, J.3
Swanson, P.4
Brennan, C.A.5
Ngansop, C.6
Mbanya, D.7
Gayum, H.8
Djuidje, M.N.9
Ndembi, N.10
-
36
-
-
33947202309
-
Genomic analysis of HIV type 1 strains derived from a mother and child pair of long-term nonprogressors
-
10.1089/aid.2006.0180. 17331038
-
Genomic analysis of HIV type 1 strains derived from a mother and child pair of long-term nonprogressors. M Reinis B Weiser C Kuiken T Dong D Lang S Nachman Y Zhang S Rowland-Jones H Burger, AIDS Res Hum Retroviruses 2007 23 309 315 10.1089/aid.2006.0180 17331038
-
(2007)
AIDS Res Hum Retroviruses
, vol.23
, pp. 309-315
-
-
Reinis, M.1
Weiser, B.2
Kuiken, C.3
Dong, T.4
Lang, D.5
Nachman, S.6
Zhang, Y.7
Rowland-Jones, S.8
Burger, H.9
-
37
-
-
33947225783
-
Molecular characterization of the HIV type 1 subtype C accessory genes vif, vpr, and vpu
-
10.1089/aid.2006.0181. 17331040
-
Molecular characterization of the HIV type 1 subtype C accessory genes vif, vpr, and vpu. CM Bell BJ Connell A Capovilla WD Venter WS Stevens MA Papathanasopoulos, AIDS Res Hum Retroviruses 2007 23 322 330 10.1089/aid.2006.0181 17331040
-
(2007)
AIDS Res Hum Retroviruses
, vol.23
, pp. 322-330
-
-
Bell, C.M.1
Connell, B.J.2
Capovilla, A.3
Venter, W.D.4
Stevens, W.S.5
Papathanasopoulos, M.A.6
-
38
-
-
42449148770
-
Molecular Characterization of the HIV Type 1 vpr Gene in Infected Chinese Former Blood/Plasma Donors at Different Stages of Diseases
-
10.1089/aid.2007.0270. 18366311
-
Molecular Characterization of the HIV Type 1 vpr Gene in Infected Chinese Former Blood/Plasma Donors at Different Stages of Diseases. C Shen P Gupta H Wu X Chen X Huang Y Zhou Y Chen, AIDS Res Hum Retroviruses 2008 24 661 666 10.1089/aid.2007.0270 18366311
-
(2008)
AIDS Res Hum Retroviruses
, vol.24
, pp. 661-666
-
-
Shen, C.1
Gupta, P.2
Wu, H.3
Chen, X.4
Huang, X.5
Zhou, Y.6
Chen, Y.7
-
39
-
-
0029925230
-
Consistent risk group-associated differences in human immunodeficiency virus type 1 vpr, vpu and V3 sequences despite independent evolution
-
10.1099/0022-1317-77-4-783. 8627267
-
Consistent risk group-associated differences in human immunodeficiency virus type 1 vpr, vpu and V3 sequences despite independent evolution. CL Kuiken MT Cornelissen F Zorgdrager S Hartman AJ Gibbs J Goudsmit, J Gen Virol 1996 77 Pt 4 783 792 10.1099/0022-1317-77-4-783 8627267
-
(1996)
J Gen Virol
, vol.77
, Issue.PART 4
, pp. 783-792
-
-
Kuiken, C.L.1
Cornelissen, M.T.2
Zorgdrager, F.3
Hartman, S.4
Gibbs, A.J.5
Goudsmit, J.6
-
40
-
-
0037436404
-
NMR structure of the HIV-1 regulatory protein VPR
-
10.1016/S0022-2836(03)00060-3. 12614620
-
NMR structure of the HIV-1 regulatory protein VPR. N Morellet S Bouaziz P Petitjean BP Roques, J Mol Biol 2003 327 215 227 10.1016/S0022-2836(03)00060-3 12614620
-
(2003)
J Mol Biol
, vol.327
, pp. 215-227
-
-
Morellet, N.1
Bouaziz, S.2
Petitjean, P.3
Roques, B.P.4
-
41
-
-
0037047072
-
Evidence for a cytopathogenicity determinant in HIV-1 Vpr
-
12093916. 10.1073/pnas.142313699
-
Evidence for a cytopathogenicity determinant in HIV-1 Vpr. M Somasundaran M Sharkey B Brichacek K Luzuriaga M Emerman JL Sullivan M Stevenson, Proc Natl Acad Sci USA 2002 99 9503 9508 12093916 10.1073/pnas.142313699
-
(2002)
Proc Natl Acad Sci USA
, vol.99
, pp. 9503-9508
-
-
Somasundaran, M.1
Sharkey, M.2
Brichacek, B.3
Luzuriaga, K.4
Emerman, M.5
Sullivan, J.L.6
Stevenson, M.7
-
42
-
-
34548155662
-
Proline 35 of human immunodeficiency virus type 1 (HIV-1) Vpr regulates the integrity of the N-terminal helix and the incorporation of Vpr into virus particles and supports the replication of R5-tropic HIV-1 in human lymphoid tissue ex vivo
-
17553868. 10.1128/JVI.02803-06
-
Proline 35 of human immunodeficiency virus type 1 (HIV-1) Vpr regulates the integrity of the N-terminal helix and the incorporation of Vpr into virus particles and supports the replication of R5-tropic HIV-1 in human lymphoid tissue ex vivo. J Votteler N Studtrucker S Sorgel J Munch E Rucker F Kirchhoff B Schick P Henklein T Fossen K Bruns, J Virol 2007 81 9572 9576 17553868 10.1128/JVI.02803-06
-
(2007)
J Virol
, vol.81
, pp. 9572-9576
-
-
Votteler, J.1
Studtrucker, N.2
Sorgel, S.3
Munch, J.4
Rucker, E.5
Kirchhoff, F.6
Schick, B.7
Henklein, P.8
Fossen, T.9
Bruns, K.10
-
43
-
-
4444249423
-
Nuclear localization of Vpr is crucial for the efficient replication of HIV-1 in primary CD4+ T cells
-
10.1016/j.virol.2004.06.024. 15351213
-
Nuclear localization of Vpr is crucial for the efficient replication of HIV-1 in primary CD4+ T cells. S Iijima Y Nitahara-Kasahara K Kimata W Zhong Zhuang M Kamata M Isogai M Miwa Y Tsunetsugu-Yokota Y Aida, Virology 2004 327 249 261 10.1016/j.virol.2004.06.024 15351213
-
(2004)
Virology
, vol.327
, pp. 249-261
-
-
Iijima, S.1
Nitahara-Kasahara, Y.2
Kimata, K.3
Zhong Zhuang, W.4
Kamata, M.5
Isogai, M.6
Miwa, M.7
Tsunetsugu-Yokota, Y.8
Aida, Y.9
-
44
-
-
0028824894
-
Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr
-
7494303
-
Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr. P Di Marzio S Choe M Ebright R Knoblauch NR Landau, J Virol 1995 69 7909 7916 7494303
-
(1995)
J Virol
, vol.69
, pp. 7909-7916
-
-
Di Marzio, P.1
Choe, S.2
Ebright, M.3
Knoblauch, R.4
Landau, N.R.5
-
45
-
-
0028963445
-
Identification of residues in the N-terminal acidic domain of HIV-1 Vpr essential for virion incorporation
-
10.1006/viro.1995.1081. 7871742
-
Identification of residues in the N-terminal acidic domain of HIV-1 Vpr essential for virion incorporation. S Mahalingam SA Khan MA Jabbar CE Monken RG Collman A Srinivasan, Virology 1995 207 297 302 10.1006/viro.1995.1081 7871742
-
(1995)
Virology
, vol.207
, pp. 297-302
-
-
Mahalingam, S.1
Khan, S.A.2
Jabbar, M.A.3
Monken, C.E.4
Collman, R.G.5
Srinivasan, A.6
-
46
-
-
0028988970
-
Mutagenesis of the putative alpha-helical domain of the Vpr protein of human immunodeficiency virus type 1: Effect on stability and virion incorporation
-
7731985. 10.1073/pnas.92.9.3794
-
Mutagenesis of the putative alpha-helical domain of the Vpr protein of human immunodeficiency virus type 1: effect on stability and virion incorporation. S Mahalingam SA Khan R Murali MA Jabbar CE Monken RG Collman A Srinivasan, Proc Natl Acad Sci USA 1995 92 3794 3798 7731985 10.1073/pnas.92.9.3794
-
(1995)
Proc Natl Acad Sci USA
, vol.92
, pp. 3794-3798
-
-
Mahalingam, S.1
Khan, S.A.2
Murali, R.3
Jabbar, M.A.4
Monken, C.E.5
Collman, R.G.6
Srinivasan, A.7
-
47
-
-
0027429412
-
Incorporation of Vpr into human immunodeficiency virus type 1 virions: Requirement for the p6 region of gag and mutational analysis
-
8230445
-
Incorporation of Vpr into human immunodeficiency virus type 1 virions: requirement for the p6 region of gag and mutational analysis. W Paxton RI Connor NR Landau, J Virol 1993 67 7229 7237 8230445
-
(1993)
J Virol
, vol.67
, pp. 7229-7237
-
-
Paxton, W.1
Connor, R.I.2
Landau, N.R.3
-
48
-
-
0036827721
-
The first HxRxG motif in simian immunodeficiency virus mac239 Vpr is crucial for G(2)/M cell cycle arrest
-
12388729. 10.1128/JVI.76.22.11704-11709.2002
-
The first HxRxG motif in simian immunodeficiency virus mac239 Vpr is crucial for G(2)/M cell cycle arrest. SM Mueller SM Lang, J Virol 2002 76 11704 11709 12388729 10.1128/JVI.76.22.11704-11709.2002
-
(2002)
J Virol
, vol.76
, pp. 11704-11709
-
-
Mueller, S.M.1
Lang, S.M.2
-
49
-
-
0036801253
-
Functional conservation of HIV-1 Vpr and variability in a mother-child pair of long-term non-progressors
-
10.1016/S0168-1702(02)00127-2. 12367754
-
Functional conservation of HIV-1 Vpr and variability in a mother-child pair of long-term non-progressors. Y Zhao M Chen B Wang J Yang RT Elder XQ Song M Yu NK Saksena, Virus Res 2002 89 103 121 10.1016/S0168-1702(02)00127-2 12367754
-
(2002)
Virus Res
, vol.89
, pp. 103-121
-
-
Zhao, Y.1
Chen, M.2
Wang, B.3
Yang, J.4
Elder, R.T.5
Song, X.Q.6
Yu, M.7
Saksena, N.K.8
-
50
-
-
4544322878
-
Structure-functional analysis of human immunodeficiency virus type 1 (HIV-1) Vpr: Role of leucine residues on Vpr-mediated transactivation and virus replication
-
10.1016/j.virol.2004.07.013. 15380361
-
Structure-functional analysis of human immunodeficiency virus type 1 (HIV-1) Vpr: role of leucine residues on Vpr-mediated transactivation and virus replication. D Thotala EA Schafer PK Tungaturthi B Majumder ML Janket M Wagner A Srinivasan S Watkins V Ayyavoo, Virology 2004 328 89 100 10.1016/j.virol.2004. 07.013 15380361
-
(2004)
Virology
, vol.328
, pp. 89-100
-
-
Thotala, D.1
Schafer, E.A.2
Tungaturthi, P.K.3
Majumder, B.4
Janket, M.L.5
Wagner, M.6
Srinivasan, A.7
Watkins, S.8
Ayyavoo, V.9
-
51
-
-
38649100975
-
Localization of HIV-1 Vpr to the nuclear envelope: Impact on Vpr functions and virus replication in macrophages
-
18039376. 10.1186/1742-4690-4-84
-
Localization of HIV-1 Vpr to the nuclear envelope: impact on Vpr functions and virus replication in macrophages. G Jacquot E Le Rouzic A David J Mazzolini J Bouchet S Bouaziz F Niedergang G Pancino S Benichou, Retrovirology 2007 4 84 18039376 10.1186/1742-4690-4-84
-
(2007)
Retrovirology
, vol.4
, pp. 84
-
-
Jacquot, G.1
Le Rouzic, E.2
David, A.3
Mazzolini, J.4
Bouchet, J.5
Bouaziz, S.6
Niedergang, F.7
Pancino, G.8
Benichou, S.9
-
52
-
-
0032509090
-
Human immunodeficiency virus type 1 vpr protein transactivation function: Mechanism and identification of domains involved
-
10.1006/jmbi.1998.2206. 9837715
-
Human immunodeficiency virus type 1 vpr protein transactivation function: mechanism and identification of domains involved. J Forget XJ Yao J Mercier EA Cohen, J Mol Biol 1998 284 915 923 10.1006/jmbi.1998.2206 9837715
-
(1998)
J Mol Biol
, vol.284
, pp. 915-923
-
-
Forget, J.1
Yao, X.J.2
Mercier, J.3
Cohen, E.A.4
-
53
-
-
0028840657
-
Mutagenic analysis of human immunodeficiency virus type 1 Vpr: Role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation
-
7474123
-
Mutagenic analysis of human immunodeficiency virus type 1 Vpr: role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation. XJ Yao RA Subbramanian N Rougeau F Boisvert D Bergeron EA Cohen, J Virol 1995 69 7032 7044 7474123
-
(1995)
J Virol
, vol.69
, pp. 7032-7044
-
-
Yao, X.J.1
Subbramanian, R.A.2
Rougeau, N.3
Boisvert, F.4
Bergeron, D.5
Cohen, E.A.6
-
54
-
-
0033050673
-
Mutational analysis of Vpr-induced G2 arrest, nuclear localization, and cell death in fission yeast
-
10074177
-
Mutational analysis of Vpr-induced G2 arrest, nuclear localization, and cell death in fission yeast. M Chen RT Elder M Yu MG O'Gorman L Selig R Benarous A Yamamoto Y Zhao, J Virol 1999 73 3236 3245 10074177
-
(1999)
J Virol
, vol.73
, pp. 3236-3245
-
-
Chen, M.1
Elder, R.T.2
Yu, M.3
O'Gorman, M.G.4
Selig, L.5
Benarous, R.6
Yamamoto, A.7
Zhao, Y.8
-
55
-
-
0031975959
-
HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection
-
9436978. 10.1101/gad.12.2.175
-
HIV-1 Vpr interacts with the nuclear transport pathway to promote macrophage infection. MA Vodicka DM Koepp PA Silver M Emerman, Genes Dev 1998 12 175 185 9436978 10.1101/gad.12.2.175
-
(1998)
Genes Dev
, vol.12
, pp. 175-185
-
-
Vodicka, M.A.1
Koepp, D.M.2
Silver, P.A.3
Emerman, M.4
-
56
-
-
0033755616
-
Functional role of residues corresponding to helical domain II (amino acids 35 to 46) of human immunodeficiency virus type 1 Vpr
-
11044109. 10.1128/JVI.74.22.10650-10657.2000
-
Functional role of residues corresponding to helical domain II (amino acids 35 to 46) of human immunodeficiency virus type 1 Vpr. SP Singh B Tomkowicz D Lai M Cartas S Mahalingam VS Kalyanaraman R Murali A Srinivasan, J Virol 2000 74 10650 10657 11044109 10.1128/JVI.74.22.10650-10657.2000
-
(2000)
J Virol
, vol.74
, pp. 10650-10657
-
-
Singh, S.P.1
Tomkowicz, B.2
Lai, D.3
Cartas, M.4
Mahalingam, S.5
Kalyanaraman, V.S.6
Murali, R.7
Srinivasan, A.8
-
57
-
-
0033942182
-
Two putative alpha-helical domains of human immunodeficiency virus type 1 Vpr mediate nuclear localization by at least two mechanisms
-
10888660. 10.1128/JVI.74.15.7179-7186.2000
-
Two putative alpha-helical domains of human immunodeficiency virus type 1 Vpr mediate nuclear localization by at least two mechanisms. M Kamata Y Aida, J Virol 2000 74 7179 7186 10888660 10.1128/JVI.74.15.7179-7186.2000
-
(2000)
J Virol
, vol.74
, pp. 7179-7186
-
-
Kamata, M.1
Aida, Y.2
-
58
-
-
34548168775
-
Vpr cytopathicity independent of G2/M cell cycle arrest in human immunodeficiency virus type 1-infected CD4+ T cells
-
17553871. 10.1128/JVI.00122-07
-
Vpr cytopathicity independent of G2/M cell cycle arrest in human immunodeficiency virus type 1-infected CD4+ T cells. DL Bolton MJ Lenardo, J Virol 2007 81 8878 8890 17553871 10.1128/JVI.00122-07
-
(2007)
J Virol
, vol.81
, pp. 8878-8890
-
-
Bolton, D.L.1
Lenardo, M.J.2
-
59
-
-
0038805579
-
Nuclear export of Vpr is required for efficient replication of human immunodeficiency virus type 1 in tissue macrophages
-
12805458. 10.1128/JVI.77.13.7582-7589.2003
-
Nuclear export of Vpr is required for efficient replication of human immunodeficiency virus type 1 in tissue macrophages. MP Sherman CM de Noronha LA Eckstein J Hataye P Mundt SA Williams JA Neidleman MA Goldsmith WC Greene, J Virol 2003 77 7582 7589 12805458 10.1128/JVI.77.13.7582-7589.2003
-
(2003)
J Virol
, vol.77
, pp. 7582-7589
-
-
Sherman, M.P.1
De Noronha, C.M.2
Eckstein, L.A.3
Hataye, J.4
Mundt, P.5
Williams, S.A.6
Neidleman, J.A.7
Goldsmith, M.A.8
Greene, W.C.9
-
60
-
-
0030824787
-
Nuclear import, virion incorporation, and cell cycle arrest/ differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr
-
9261351
-
Nuclear import, virion incorporation, and cell cycle arrest/ differentiation are mediated by distinct functional domains of human immunodeficiency virus type 1 Vpr. S Mahalingam V Ayyavoo M Patel T Kieber-Emmons DB Weiner, J Virol 1997 71 6339 6347 9261351
-
(1997)
J Virol
, vol.71
, pp. 6339-6347
-
-
Mahalingam, S.1
Ayyavoo, V.2
Patel, M.3
Kieber-Emmons, T.4
Weiner, D.B.5
-
61
-
-
34648833229
-
DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest
-
17626091. 10.1128/JVI.01380-07
-
DDB1 and Cul4A are required for human immunodeficiency virus type 1 Vpr-induced G2 arrest. L Tan E Ehrlich XF Yu, J Virol 2007 81 10822 10830 17626091 10.1128/JVI.01380-07
-
(2007)
J Virol
, vol.81
, pp. 10822-10830
-
-
Tan, L.1
Ehrlich, E.2
Yu, X.F.3
-
62
-
-
34547395804
-
Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle
-
17609381. 10.1073/pnas.0702102104
-
Lentiviral Vpr usurps Cul4-DDB1[VprBP] E3 ubiquitin ligase to modulate cell cycle. K Hrecka M Gierszewska S Srivastava L Kozaczkiewicz SK Swanson L Florens MP Washburn J Skowronski, Proc Natl Acad Sci USA 2007 104 11778 11783 17609381 10.1073/pnas.0702102104
-
(2007)
Proc Natl Acad Sci USA
, vol.104
, pp. 11778-11783
-
-
Hrecka, K.1
Gierszewska, M.2
Srivastava, S.3
Kozaczkiewicz, L.4
Swanson, S.K.5
Florens, L.6
Washburn, M.P.7
Skowronski, J.8
-
63
-
-
0036402949
-
Transcription factor TFIIH components enhance the GR coactivator activity but not the cell cycle-arresting activity of the human immunodeficiency virus type-1 protein Vpr
-
10.1016/S0006-291X(02)02442-7. 12379213
-
Transcription factor TFIIH components enhance the GR coactivator activity but not the cell cycle-arresting activity of the human immunodeficiency virus type-1 protein Vpr. T Kino M Tsukamoto G Chrousos, Biochem Biophys Res Commun 2002 298 17 23 10.1016/S0006-291X(02)02442-7 12379213
-
(2002)
Biochem Biophys Res Commun
, vol.298
, pp. 17-23
-
-
Kino, T.1
Tsukamoto, M.2
Chrousos, G.3
-
64
-
-
0033882196
-
Human immunodeficiency virus type 1 Vpr contains two leucine-rich helices that mediate glucocorticoid receptor coactivation independently of its effects on G(2) cell cycle arrest
-
10933727. 10.1128/JVI.74.17.8159-8165.2000
-
Human immunodeficiency virus type 1 Vpr contains two leucine-rich helices that mediate glucocorticoid receptor coactivation independently of its effects on G(2) cell cycle arrest. MP Sherman CM de Noronha D Pearce WC Greene, J Virol 2000 74 8159 8165 10933727 10.1128/JVI.74.17.8159-8165.2000
-
(2000)
J Virol
, vol.74
, pp. 8159-8165
-
-
Sherman, M.P.1
De Noronha, C.M.2
Pearce, D.3
Greene, W.C.4
-
65
-
-
0035882082
-
A novel inducible expression system to study transdominant mutants of HIV-1 Vpr
-
10.1006/viro.2001.1031. 11504548
-
A novel inducible expression system to study transdominant mutants of HIV-1 Vpr. Y Zhou L Ratner, Virology 2001 287 133 142 10.1006/viro.2001.1031 11504548
-
(2001)
Virology
, vol.287
, pp. 133-142
-
-
Zhou, Y.1
Ratner, L.2
-
66
-
-
39749184106
-
Human immunodeficiency virus type 1 Vpr inhibits axonal outgrowth through induction of mitochondrial dysfunction
-
18094160. 10.1128/JVI.02094-07
-
Human immunodeficiency virus type 1 Vpr inhibits axonal outgrowth through induction of mitochondrial dysfunction. H Kitayama Y Miura Y Ando S Hoshino Y Ishizaka Y Koyanagi, J Virol 2008 82 2528 2542 18094160 10.1128/JVI.02094-07
-
(2008)
J Virol
, vol.82
, pp. 2528-2542
-
-
Kitayama, H.1
Miura, Y.2
Ando, Y.3
Hoshino, S.4
Ishizaka, Y.5
Koyanagi, Y.6
-
67
-
-
0032520546
-
Arginine residues in the C-terminus of HIV-1 Vpr are important for nuclear localization and cell cycle arrest
-
10.1006/viro.1998.9028. 9514978
-
Arginine residues in the C-terminus of HIV-1 Vpr are important for nuclear localization and cell cycle arrest. Y Zhou Y Lu L Ratner, Virology 1998 242 414 424 10.1006/viro.1998.9028 9514978
-
(1998)
Virology
, vol.242
, pp. 414-424
-
-
Zhou, Y.1
Lu, Y.2
Ratner, L.3
-
68
-
-
0036205110
-
Phosphorylation of Vpr regulates HIV type 1 nuclear import and macrophage infection
-
10.1089/088922202753472856. 11860675
-
Phosphorylation of Vpr regulates HIV type 1 nuclear import and macrophage infection. I Agostini S Popov T Hao JH Li L Dubrovsky O Chaika N Chaika R Lewis M Bukrinsky, AIDS Res Hum Retroviruses 2002 18 283 288 10.1089/ 088922202753472856 11860675
-
(2002)
AIDS Res Hum Retroviruses
, vol.18
, pp. 283-288
-
-
Agostini, I.1
Popov, S.2
Hao, T.3
Li, J.H.4
Dubrovsky, L.5
Chaika, O.6
Chaika, N.7
Lewis, R.8
Bukrinsky, M.9
-
69
-
-
0037791747
-
Viral escape from dominant simian immunodeficiency virus epitope-specific cytotoxic T lymphocytes in DNA-vaccinated rhesus monkeys
-
12805435. 10.1128/JVI.77.13.7367-7375.2003
-
Viral escape from dominant simian immunodeficiency virus epitope-specific cytotoxic T lymphocytes in DNA-vaccinated rhesus monkeys. DH Barouch J Kunstman J Glowczwskie KJ Kunstman MA Egan FW Peyerl S Santra MJ Kuroda JE Schmitz K Beaudry, J Virol 2003 77 7367 7375 12805435 10.1128/JVI.77.13.7367-7375.2003
-
(2003)
J Virol
, vol.77
, pp. 7367-7375
-
-
Barouch, D.H.1
Kunstman, J.2
Glowczwskie, J.3
Kunstman, K.J.4
Egan, M.A.5
Peyerl, F.W.6
Santra, S.7
Kuroda, M.J.8
Schmitz, J.E.9
Beaudry, K.10
-
70
-
-
0002716966
-
Immunological and pharmacological approaches to the control of retroviral infections
-
Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York Coffin JM, Hughes SH, Varmus HE
-
Immunological and pharmacological approaches to the control of retroviral infections. EA Emini HY Fan, "Retroviruses" Cold Spring Harbor Laboratory Press, Cold Spring Harbor, New York, Coffin JM, Hughes SH, Varmus HE, 1997 637 706
-
(1997)
Retroviruses
, pp. 637-706
-
-
Emini, E.A.1
Fan, H.Y.2
-
71
-
-
38049094546
-
Antibody-based HIV-1 vaccines: Recent developments and future directions
-
18052607. 10.1371/journal.pmed.0040348
-
Antibody-based HIV-1 vaccines: recent developments and future directions. D Montefiori Q Sattentau J Flores J Esparza J Mascola, PLoS Med 2007 4 e348 18052607 10.1371/journal.pmed.0040348
-
(2007)
PLoS Med
, vol.4
, pp. 348
-
-
Montefiori, D.1
Sattentau, Q.2
Flores, J.3
Esparza, J.4
Mascola, J.5
-
72
-
-
33749474469
-
Hitting HIV where it hurts: An alternative approach to HIV vaccine design
-
10.1016/j.it.2006.09.007. 16997629
-
Hitting HIV where it hurts: an alternative approach to HIV vaccine design. M Altfeld TM Allen, Trends Immunol 2006 27 504 510 10.1016/j.it.2006.09. 007 16997629
-
(2006)
Trends Immunol
, vol.27
, pp. 504-510
-
-
Altfeld, M.1
Allen, T.M.2
-
73
-
-
1542317452
-
HIV vaccine design and the neutralizing antibody problem
-
10.1038/ni0304-233. 14985706
-
HIV vaccine design and the neutralizing antibody problem. DR Burton RC Desrosiers RW Doms WC Koff PD Kwong JP Moore GJ Nabel J Sodroski IA Wilson RT Wyatt, Nat Immunol 2004 5 233 236 10.1038/ni0304-233 14985706
-
(2004)
Nat Immunol
, vol.5
, pp. 233-236
-
-
Burton, D.R.1
Desrosiers, R.C.2
Doms, R.W.3
Koff, W.C.4
Kwong, P.D.5
Moore, J.P.6
Nabel, G.J.7
Sodroski, J.8
Wilson, I.A.9
Wyatt, R.T.10
-
74
-
-
0033559648
-
Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques
-
10075982. 10.1084/jem.189.6.991
-
Dramatic rise in plasma viremia after CD8(+) T cell depletion in simian immunodeficiency virus-infected macaques. X Jin DE Bauer SE Tuttleton S Lewin A Gettie J Blanchard CE Irwin JT Safrit J Mittler L Weinberger, J Exp Med 1999 189 991 998 10075982 10.1084/jem.189.6.991
-
(1999)
J Exp Med
, vol.189
, pp. 991-998
-
-
Jin, X.1
Bauer, D.E.2
Tuttleton, S.E.3
Lewin, S.4
Gettie, A.5
Blanchard, J.6
Irwin, C.E.7
Safrit, J.T.8
Mittler, J.9
Weinberger, L.10
-
75
-
-
0033524838
-
Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes
-
10.1126/science.283.5403.857. 9933172
-
Control of viremia in simian immunodeficiency virus infection by CD8+ lymphocytes. JE Schmitz MJ Kuroda S Santra VG Sasseville MA Simon MA Lifton P Racz K Tenner-Racz M Dalesandro BJ Scallon, Science 1999 283 857 860 10.1126/science.283.5403.857 9933172
-
(1999)
Science
, vol.283
, pp. 857-860
-
-
Schmitz, J.E.1
Kuroda, M.J.2
Santra, S.3
Sasseville, V.G.4
Simon, M.A.5
Lifton, M.A.6
Racz, P.7
Tenner-Racz, K.8
Dalesandro, M.9
Scallon, B.J.10
-
76
-
-
0035936781
-
HIV-1 sequence variation: Drift, shift, and attenuation
-
10.1016/S0092-8674(01)00234-3. 11239404
-
HIV-1 sequence variation: drift, shift, and attenuation. MH Malim M Emerman, Cell 2001 104 469 472 10.1016/S0092-8674(01)00234-3 11239404
-
(2001)
Cell
, vol.104
, pp. 469-472
-
-
Malim, M.H.1
Emerman, M.2
-
77
-
-
0035844057
-
Selection forces and constraints on retroviral sequence variation
-
10.1126/science.1059128. 11352065
-
Selection forces and constraints on retroviral sequence variation. J Overbaugh CR Bangham, Science 2001 292 1106 1109 10.1126/science.1059128 11352065
-
(2001)
Science
, vol.292
, pp. 1106-1109
-
-
Overbaugh, J.1
Bangham, C.R.2
-
78
-
-
33947399689
-
Founder effects in the assessment of HIV polymorphisms and HLA allele associations
-
10.1126/science.1131528. 17363674
-
Founder effects in the assessment of HIV polymorphisms and HLA allele associations. T Bhattacharya M Daniels D Heckerman B Foley N Frahm C Kadie J Carlson K Yusim B McMahon B Gaschen, Science 2007 315 1583 1586 10.1126/science.1131528 17363674
-
(2007)
Science
, vol.315
, pp. 1583-1586
-
-
Bhattacharya, T.1
Daniels, M.2
Heckerman, D.3
Foley, B.4
Frahm, N.5
Kadie, C.6
Carlson, J.7
Yusim, K.8
McMahon, B.9
Gaschen, B.10
-
79
-
-
0037165309
-
AIDS vaccines: On the trail of two trials
-
10.1038/415365a. 11807523
-
AIDS vaccines: on the trail of two trials. JP Moore, Nature 2002 415 365 366 10.1038/415365a 11807523
-
(2002)
Nature
, vol.415
, pp. 365-366
-
-
Moore, J.P.1
-
80
-
-
34547643061
-
Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1
-
17616974. 10.1371/journal.ppat.0030094
-
Evidence of differential HLA class I-mediated viral evolution in functional and accessory/regulatory genes of HIV-1. ZL Brumme CJ Brumme D Heckerman BT Korber M Daniels J Carlson C Kadie T Bhattacharya C Chui J Szinger, PLoS Pathog 2007 3 e94 17616974 10.1371/journal.ppat.0030094
-
(2007)
PLoS Pathog
, vol.3
, pp. 94
-
-
Brumme, Z.L.1
Brumme, C.J.2
Heckerman, D.3
Korber, B.T.4
Daniels, M.5
Carlson, J.6
Kadie, C.7
Bhattacharya, T.8
Chui, C.9
Szinger, J.10
-
81
-
-
34547138161
-
Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection
-
17507468. 10.1128/JVI.00465-07
-
Compensatory mutation partially restores fitness and delays reversion of escape mutation within the immunodominant HLA-B*5703-restricted Gag epitope in chronic human immunodeficiency virus type 1 infection. H Crawford JG Prado A Leslie S Hue I Honeyborne S Reddy M van der Stok Z Mncube C Brander C Rousseau, J Virol 2007 81 8346 8351 17507468 10.1128/JVI.00465-07
-
(2007)
J Virol
, vol.81
, pp. 8346-8351
-
-
Crawford, H.1
Prado, J.G.2
Leslie, A.3
Hue, S.4
Honeyborne, I.5
Reddy, S.6
Der Van, S.M.7
Mncube, Z.8
Brander, C.9
Rousseau, C.10
-
82
-
-
0038190811
-
Determinant of HIV-1 mutational escape from cytotoxic T lymphocytes
-
12743169. 10.1084/jem.20022138
-
Determinant of HIV-1 mutational escape from cytotoxic T lymphocytes. OO Yang PT Sarkis A Ali JD Harlow C Brander SA Kalams BD Walker, J Exp Med 2003 197 1365 1375 12743169 10.1084/jem.20022138
-
(2003)
J Exp Med
, vol.197
, pp. 1365-1375
-
-
Yang, O.O.1
Sarkis, P.T.2
Ali, A.3
Harlow, J.D.4
Brander, C.5
Kalams, S.A.6
Walker, B.D.7
-
83
-
-
10044227534
-
Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope
-
15564498. 10.1128/JVI.78.24.13901-13910.2004
-
Fitness costs limit viral escape from cytotoxic T lymphocytes at a structurally constrained epitope. FW Peyerl HS Bazick MH Newberg DH Barouch J Sodroski NL Letvin, J Virol 2004 78 13901 13910 15564498 10.1128/JVI.78.24. 13901-13910.2004
-
(2004)
J Virol
, vol.78
, pp. 13901-13910
-
-
Peyerl, F.W.1
Bazick, H.S.2
Newberg, M.H.3
Barouch, D.H.4
Sodroski, J.5
Letvin, N.L.6
-
84
-
-
20244373940
-
Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA
-
15781581. 10.1084/jem.20041455
-
Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA. A Leslie D Kavanagh I Honeyborne K Pfafferott C Edwards T Pillay L Hilton C Thobakgale D Ramduth R Draenert, J Exp Med 2005 201 891 902 15781581 10.1084/jem.20041455
-
(2005)
J Exp Med
, vol.201
, pp. 891-902
-
-
Leslie, A.1
Kavanagh, D.2
Honeyborne, I.3
Pfafferott, K.4
Edwards, C.5
Pillay, T.6
Hilton, L.7
Thobakgale, C.8
Ramduth, D.9
Draenert, R.10
-
85
-
-
10744221493
-
Extraepitopic compensatory substitutions partially restore fitness to simian immunodeficiency virus variants that escape from an immunodominant cytotoxic-T-lymphocyte response
-
14963161. 10.1128/JVI.78.5.2581-2585.2004
-
Extraepitopic compensatory substitutions partially restore fitness to simian immunodeficiency virus variants that escape from an immunodominant cytotoxic-T-lymphocyte response. TC Friedrich CA Frye LJ Yant DH O'Connor NA Kriewaldt M Benson L Vojnov EJ Dodds C Cullen R Rudersdorf, J Virol 2004 78 2581 2585 14963161 10.1128/JVI.78.5.2581-2585.2004
-
(2004)
J Virol
, vol.78
, pp. 2581-2585
-
-
Friedrich, T.C.1
Frye, C.A.2
Yant, L.J.3
O'Connor, D.H.4
Kriewaldt, N.A.5
Benson, M.6
Vojnov, L.7
Dodds, E.J.8
Cullen, C.9
Rudersdorf, R.10
-
86
-
-
20144389568
-
The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: Implications for vaccine design
-
15795285. 10.1128/JVI.79.8.5000-5005.2005
-
The majority of currently circulating human immunodeficiency virus type 1 clade B viruses fail to prime cytotoxic T-lymphocyte responses against an otherwise immunodominant HLA-A2-restricted epitope: implications for vaccine design. M Altfeld TM Allen ET Kalife N Frahm MM Addo BR Mothe A Rathod LL Reyor J Harlow XG Yu, J Virol 2005 79 5000 5005 15795285 10.1128/JVI.79.8.5000-5005. 2005
-
(2005)
J Virol
, vol.79
, pp. 5000-5005
-
-
Altfeld, M.1
Allen, T.M.2
Kalife, E.T.3
Frahm, N.4
Addo, M.M.5
Mothe, B.R.6
Rathod, A.7
Reyor, L.L.8
Harlow, J.9
Yu, X.G.10
-
87
-
-
33846101731
-
CD8+ T-cell responses to different HIV proteins have discordant associations with viral load
-
10.1038/nm1520. 17173051
-
CD8+ T-cell responses to different HIV proteins have discordant associations with viral load. P Kiepiela K Ngumbela C Thobakgale D Ramduth I Honeyborne E Moodley S Reddy C de Pierres Z Mncube N Mkhwanazi, Nat Med 2007 13 46 53 10.1038/nm1520 17173051
-
(2007)
Nat Med
, vol.13
, pp. 46-53
-
-
Kiepiela, P.1
Ngumbela, K.2
Thobakgale, C.3
Ramduth, D.4
Honeyborne, I.5
Moodley, E.6
Reddy, S.7
De Pierres, C.8
Mncube, Z.9
Mkhwanazi, N.10
-
88
-
-
0035451404
-
Vpr is preferentially targeted by CTL during HIV-1 infection
-
11509618
-
Vpr is preferentially targeted by CTL during HIV-1 infection. M Altfeld MM Addo RL Eldridge XG Yu S Thomas A Khatri D Strick MN Phillips GB Cohen SA Islam, J Immunol 2001 167 2743 2752 11509618
-
(2001)
J Immunol
, vol.167
, pp. 2743-2752
-
-
Altfeld, M.1
Addo, M.M.2
Eldridge, R.L.3
Yu, X.G.4
Thomas, S.5
Khatri, A.6
Strick, D.7
Phillips, M.N.8
Cohen, G.B.9
Islam, S.A.10
-
89
-
-
0036729032
-
Cytotoxic T-lymphocyte (CTL) responses directed against regulatory and accessory proteins in HIV-1 infection
-
10.1089/104454902760330219. 12396610
-
Cytotoxic T-lymphocyte (CTL) responses directed against regulatory and accessory proteins in HIV-1 infection. MM Addo XG Yu ES Rosenberg BD Walker M Altfeld, DNA Cell Biol 2002 21 671 678 10.1089/104454902760330219 12396610
-
(2002)
DNA Cell Biol
, vol.21
, pp. 671-678
-
-
Addo, M.M.1
Yu, X.G.2
Rosenberg, E.S.3
Walker, B.D.4
Altfeld, M.5
-
90
-
-
0037302428
-
Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load
-
12525643. 10.1128/JVI.77.3.2081-2092.2003
-
Comprehensive epitope analysis of human immunodeficiency virus type 1 (HIV-1)-specific T-cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load. MM Addo XG Yu A Rathod D Cohen RL Eldridge D Strick MN Johnston C Corcoran AG Wurcel CA Fitzpatrick, J Virol 2003 77 2081 2092 12525643 10.1128/JVI.77.3.2081- 2092.2003
-
(2003)
J Virol
, vol.77
, pp. 2081-2092
-
-
Addo, M.M.1
Yu, X.G.2
Rathod, A.3
Cohen, D.4
Eldridge, R.L.5
Strick, D.6
Johnston, M.N.7
Corcoran, C.8
Wurcel, A.G.9
Fitzpatrick, C.A.10
-
91
-
-
33750067347
-
Identification of HIV-1 specific T lymphocyte responses in highly exposed persistently seronegative Chinese
-
17042974
-
Identification of HIV-1 specific T lymphocyte responses in highly exposed persistently seronegative Chinese. HW Liu KX Hong J Ma L Yuan S Liu JP Chen YZ Zhang YH Ruan JQ Xu YM Shao, Chin Med J (Engl) 2006 119 1616 1621 17042974
-
(2006)
Chin Med J (Engl)
, vol.119
, pp. 1616-1621
-
-
Liu, H.W.1
Hong, K.X.2
Ma, J.3
Yuan, L.4
Liu, S.5
Chen, J.P.6
Zhang, Y.Z.7
Ruan, Y.H.8
Xu, J.Q.9
Shao, Y.M.10
-
92
-
-
0037942696
-
Comprehensive analysis of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon-secreting CD8+ T cells in primary HIV-1 infection
-
12768006. 10.1128/JVI.77.12.6867-6878.2003
-
Comprehensive analysis of human immunodeficiency virus type 1 (HIV-1)-specific gamma interferon-secreting CD8+ T cells in primary HIV-1 infection. J Cao J McNevin S Holte L Fink L Corey MJ McElrath, J Virol 2003 77 6867 6878 12768006 10.1128/JVI.77.12.6867-6878.2003
-
(2003)
J Virol
, vol.77
, pp. 6867-6878
-
-
Cao, J.1
McNevin, J.2
Holte, S.3
Fink, L.4
Corey, L.5
McElrath, M.J.6
-
93
-
-
14644415425
-
Immunodominance of HIV-1-specific CD8(+) T-cell responses in acute HIV-1 infection: At the crossroads of viral and host genetics
-
10.1016/j.it.2005.01.003. 15745859
-
Immunodominance of HIV-1-specific CD8(+) T-cell responses in acute HIV-1 infection: at the crossroads of viral and host genetics. M Lichterfeld XG Yu S Le Gall M Altfeld, Trends Immunol 2005 26 166 171 10.1016/j.it.2005.01.003 15745859
-
(2005)
Trends Immunol
, vol.26
, pp. 166-171
-
-
Lichterfeld, M.1
Yu, X.G.2
Le Gall, S.3
Altfeld, M.4
-
94
-
-
31344462038
-
Identification of HIV-derived HLA class I restricted CTL epitope: Insights into TCR repertoire, CTL escape and viral fitness
-
Los Alamos National Laboratory, Theoritical Biology and Biophysics, Los Alamos, New Mexico
-
Identification of HIV-derived HLA class I restricted CTL epitope: Insights into TCR repertoire, CTL escape and viral fitness. N Frahm C Linde C Brander, "HIV Molecular Immunology 2006" Los Alamos National Laboratory, Theoritical Biology and Biophysics, Los Alamos, New Mexico 2007 3
-
(2007)
"hIV Molecular Immunology 2006"
, pp. 3
-
-
Frahm, N.1
Linde, C.2
Brander, C.3
-
95
-
-
20444412370
-
HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response
-
15944251
-
HIV-1 viral escape in infancy followed by emergence of a variant-specific CTL response. ME Feeney Y Tang K Pfafferott KA Roosevelt R Draenert A Trocha XG Yu C Verrill T Allen C Moore, J Immunol 2005 174 7524 7530 15944251
-
(2005)
J Immunol
, vol.174
, pp. 7524-7530
-
-
Feeney, M.E.1
Tang, Y.2
Pfafferott, K.3
Roosevelt, K.A.4
Draenert, R.5
Trocha, A.6
Yu, X.G.7
Verrill, C.8
Allen, T.9
Moore, C.10
-
96
-
-
0036784572
-
Magnitude and frequency of cytotoxic T-lymphocyte responses: Identification of immunodominant regions of human immunodeficiency virus type 1 subtype C
-
12239290. 10.1128/JVI.76.20.10155-10168.2002
-
Magnitude and frequency of cytotoxic T-lymphocyte responses: identification of immunodominant regions of human immunodeficiency virus type 1 subtype C. V Novitsky H Cao N Rybak P Gilbert MF McLane S Gaolekwe T Peter I Thior T Ndung'u R Marlink, J Virol 2002 76 10155 10168 12239290 10.1128/JVI.76.20.10155-10168.2002
-
(2002)
J Virol
, vol.76
, pp. 10155-10168
-
-
Novitsky, V.1
Cao, H.2
Rybak, N.3
Gilbert, P.4
McLane, M.F.5
Gaolekwe, S.6
Peter, T.7
Thior, I.8
Ndung'U, T.9
Marlink, R.10
-
97
-
-
34548794906
-
Extensive HLA class I allele promiscuity among viral CTL epitopes
-
10.1002/eji.200737365. 17705138
-
Extensive HLA class I allele promiscuity among viral CTL epitopes. N Frahm K Yusim TJ Suscovich S Adams J Sidney P Hraber HS Hewitt CH Linde DG Kavanagh T Woodberry, Eur J Immunol 2007 37 2419 2433 10.1002/eji.200737365 17705138
-
(2007)
Eur J Immunol
, vol.37
, pp. 2419-2433
-
-
Frahm, N.1
Yusim, K.2
Suscovich, T.J.3
Adams, S.4
Sidney, J.5
Hraber, P.6
Hewitt, H.S.7
Linde, C.H.8
Kavanagh, D.G.9
Woodberry, T.10
-
98
-
-
0035152281
-
Identification of novel HLA-A2-restricted human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte epitopes predicted by the HLA-A2 supertype peptide-binding motif
-
11152503. 10.1128/JVI.75.3.1301-1311.2001
-
Identification of novel HLA-A2-restricted human immunodeficiency virus type 1-specific cytotoxic T-lymphocyte epitopes predicted by the HLA-A2 supertype peptide-binding motif. MA Altfeld B Livingston N Reshamwala PT Nguyen MM Addo A Shea M Newman J Fikes J Sidney P Wentworth, J Virol 2001 75 1301 1311 11152503 10.1128/JVI.75.3.1301-1311.2001
-
(2001)
J Virol
, vol.75
, pp. 1301-1311
-
-
Altfeld, M.A.1
Livingston, B.2
Reshamwala, N.3
Nguyen, P.T.4
Addo, M.M.5
Shea, A.6
Newman, M.7
Fikes, J.8
Sidney, J.9
Wentworth, P.10
-
99
-
-
0041852667
-
Optimization and immune recognition of multiple novel conserved HLA-A2, human immunodeficiency virus type 1-specific CTL epitopes
-
10.1099/vir.0.19152-0. 12917462
-
Optimization and immune recognition of multiple novel conserved HLA-A2, human immunodeficiency virus type 1-specific CTL epitopes. S Corbet HV Nielsen L Vinner S Lauemoller D Therrien S Tang G Kronborg L Mathiesen P Chaplin S Brunak, J Gen Virol 2003 84 2409 2421 10.1099/vir.0.19152-0 12917462
-
(2003)
J Gen Virol
, vol.84
, pp. 2409-2421
-
-
Corbet, S.1
Nielsen, H.V.2
Vinner, L.3
Lauemoller, S.4
Therrien, D.5
Tang, S.6
Kronborg, G.7
Mathiesen, L.8
Chaplin, P.9
Brunak, S.10
-
100
-
-
0036340339
-
Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infection
-
12163589. 10.1128/JVI.76.17.8690-8701.2002
-
Consistent patterns in the development and immunodominance of human immunodeficiency virus type 1 (HIV-1)-specific CD8+ T-cell responses following acute HIV-1 infection. XG Yu MM Addo ES Rosenberg WR Rodriguez PK Lee CA Fitzpatrick MN Johnston D Strick PJ Goulder BD Walker M Altfeld, J Virol 2002 76 8690 8701 12163589 10.1128/JVI.76.17.8690-8701.2002
-
(2002)
J Virol
, vol.76
, pp. 8690-8701
-
-
Yu, X.G.1
Addo, M.M.2
Rosenberg, E.S.3
Rodriguez, W.R.4
Lee, P.K.5
Fitzpatrick, C.A.6
Johnston, M.N.7
Strick, D.8
Goulder, P.J.9
Walker, B.D.10
Altfeld, M.11
-
101
-
-
23844539631
-
Human immunodeficiency virus mutations during the first month of infection are preferentially found in known cytotoxic T-lymphocyte epitopes
-
16103205. 10.1128/JVI.79.17.11523-11528.2005
-
Human immunodeficiency virus mutations during the first month of infection are preferentially found in known cytotoxic T-lymphocyte epitopes. F Bernardin D Kong L Peddada LA Baxter-Lowe E Delwart, J Virol 2005 79 11523 11528 16103205 10.1128/JVI.79.17.11523-11528.2005
-
(2005)
J Virol
, vol.79
, pp. 11523-11528
-
-
Bernardin, F.1
Kong, D.2
Peddada, L.3
Baxter-Lowe, L.A.4
Delwart, E.5
-
102
-
-
10644267588
-
Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA
-
10.1038/nature03113. 15592417
-
Dominant influence of HLA-B in mediating the potential co-evolution of HIV and HLA. P Kiepiela AJ Leslie I Honeyborne D Ramduth C Thobakgale S Chetty P Rathnavalu C Moore KJ Pfafferott L Hilton, Nature 2004 432 769 775 10.1038/nature03113 15592417
-
(2004)
Nature
, vol.432
, pp. 769-775
-
-
Kiepiela, P.1
Leslie, A.J.2
Honeyborne, I.3
Ramduth, D.4
Thobakgale, C.5
Chetty, S.6
Rathnavalu, P.7
Moore, C.8
Pfafferott, K.J.9
Hilton, L.10
-
103
-
-
26444448384
-
De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection
-
16188997. 10.1128/JVI.79.20.12952-12960.2005
-
De novo generation of escape variant-specific CD8+ T-cell responses following cytotoxic T-lymphocyte escape in chronic human immunodeficiency virus type 1 infection. TM Allen XG Yu ET Kalife LL Reyor M Lichterfeld M John M Cheng RL Allgaier S Mui N Frahm, J Virol 2005 79 12952 12960 16188997 10.1128/JVI.79.20.12952-12960.2005
-
(2005)
J Virol
, vol.79
, pp. 12952-12960
-
-
Allen, T.M.1
Yu, X.G.2
Kalife, E.T.3
Reyor, L.L.4
Lichterfeld, M.5
John, M.6
Cheng, M.7
Allgaier, R.L.8
Mui, S.9
Frahm, N.10
-
104
-
-
0042872480
-
Expression and functional activity of isotype and subclass switched human monoclonal antibody reactive with the base of the V3 loop of HIV-1 gp120
-
10.1089/088922203322230969. 12908937
-
Expression and functional activity of isotype and subclass switched human monoclonal antibody reactive with the base of the V3 loop of HIV-1 gp120. F Liu PL Bergami M Duval D Kuhrt M Posner L Cavacini, AIDS Res Hum Retroviruses 2003 19 597 607 10.1089/088922203322230969 12908937
-
(2003)
AIDS Res Hum Retroviruses
, vol.19
, pp. 597-607
-
-
Liu, F.1
Bergami, P.L.2
Duval, M.3
Kuhrt, D.4
Posner, M.5
Cavacini, L.6
-
105
-
-
0034987091
-
Spreading of HIV-specific CD8+ T-cell repertoire in long-term nonprogressors and its role in the control of viral load and disease activity
-
10.1016/S0198-8859(01)00245-2. 11390031
-
Spreading of HIV-specific CD8+ T-cell repertoire in long-term nonprogressors and its role in the control of viral load and disease activity. A Propato E Schiaffella E Vicenzi V Francavilla L Baloni M Paroli L Finocchi N Tanigaki S Ghezzi R Ferrara, Hum Immunol 2001 62 561 576 10.1016/S0198-8859(01) 00245-2 11390031
-
(2001)
Hum Immunol
, vol.62
, pp. 561-576
-
-
Propato, A.1
Schiaffella, E.2
Vicenzi, E.3
Francavilla, V.4
Baloni, L.5
Paroli, M.6
Finocchi, L.7
Tanigaki, N.8
Ghezzi, S.9
Ferrara, R.10
-
106
-
-
0035148309
-
Rapid definition of five novel HLA-A*3002-restricted human immunodeficiency virus-specific cytotoxic T-lymphocyte epitopes by elispot and intracellular cytokine staining assays
-
11152507. 10.1128/JVI.75.3.1339-1347.2001
-
Rapid definition of five novel HLA-A*3002-restricted human immunodeficiency virus-specific cytotoxic T-lymphocyte epitopes by elispot and intracellular cytokine staining assays. PJ Goulder MM Addo MA Altfeld ES Rosenberg Y Tang U Govender N Mngqundaniso K Annamalai TU Vogel M Hammond, J Virol 2001 75 1339 1347 11152507 10.1128/JVI.75.3.1339-1347.2001
-
(2001)
J Virol
, vol.75
, pp. 1339-1347
-
-
Goulder, P.J.1
Addo, M.M.2
Altfeld, M.A.3
Rosenberg, E.S.4
Tang, Y.5
Govender, U.6
Mngqundaniso, N.7
Annamalai, K.8
Vogel, T.U.9
Hammond, M.10
|