메뉴 건너뛰기




Volumn 37, Issue 9, 2007, Pages 2419-2433

Extensive HLA class I allele promiscuity among viral CTL epitopes

(29)  Frahm, Nicole a   Yusim, Karina b   Suscovich, Todd J a   Adams, Sharon c   Sidney, John d   Hraber, Peter b   Hewitt, Hannah S a   Linde, Caitlyn H a   Kavanagh, Daniel G a   Woodberry, Tonia a   Henry, Leah M a   Faircloth, Kellie a   Listgarten, Jennifer e   Kadie, Carl e   Jojic, Nebosajsa e   Sango, Kaori a   Brown, Nancy V a   Pae, Eunice f   Zaman, M Tauheed g   Bihl, Florian a   more..


Author keywords

Antigen; Bioinformatics; CD8 T cells; HIV; Immune responses

Indexed keywords

EPITOPE; HLA ANTIGEN CLASS 1; VIRUS ANTIGEN;

EID: 34548794906     PISSN: 00142980     EISSN: None     Source Type: Journal    
DOI: 10.1002/eji.200737365     Document Type: Article
Times cited : (112)

References (58)
  • 1
    • 0026618817 scopus 로고
    • Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle
    • Guo, H. C., Jardetzky, T. S., Garrett, T. P., Lane, W. S., Strominger, J. L. and Wiley, D. C., Different length peptides bind to HLA-Aw68 similarly at their ends but bulge out in the middle. Nature 1992. 360: 364-366.
    • (1992) Nature , vol.360 , pp. 364-366
    • Guo, H.C.1    Jardetzky, T.S.2    Garrett, T.P.3    Lane, W.S.4    Strominger, J.L.5    Wiley, D.C.6
  • 2
    • 0028943275 scopus 로고
    • The three-dimensional structure of peptide-MHC complexes
    • Madden, D. R., The three-dimensional structure of peptide-MHC complexes. Annu. Rev. Immunol. 1995. 13: 587-622.
    • (1995) Annu. Rev. Immunol , vol.13 , pp. 587-622
    • Madden, D.R.1
  • 3
    • 0026728457 scopus 로고
    • Emerging principles for the recognition of peptide antigens by MHC class I molecules
    • Matsumura, M., Fremont, D. H., Peterson, P. A. and Wilson, I. A., Emerging principles for the recognition of peptide antigens by MHC class I molecules. Science 1992. 257: 927-934.
    • (1992) Science , vol.257 , pp. 927-934
    • Matsumura, M.1    Fremont, D.H.2    Peterson, P.A.3    Wilson, I.A.4
  • 4
    • 0025855156 scopus 로고
    • Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules
    • Falk, K., Rotzschke, O., Stevanovic, S., Jung, G. and Rammensee, H. G., Allele-specific motifs revealed by sequencing of self-peptides eluted from MHC molecules. Nature 1991. 351: 290-296.
    • (1991) Nature , vol.351 , pp. 290-296
    • Falk, K.1    Rotzschke, O.2    Stevanovic, S.3    Jung, G.4    Rammensee, H.G.5
  • 5
    • 0026010271 scopus 로고
    • Precise prediction of a dominant class I MHC-restricted epitope of Listeria monocytogenes
    • Pamer, E. G., Harty, J. T. and Bevan, M. J., Precise prediction of a dominant class I MHC-restricted epitope of Listeria monocytogenes. Nature 1991. 353: 852-855.
    • (1991) Nature , vol.353 , pp. 852-855
    • Pamer, E.G.1    Harty, J.T.2    Bevan, M.J.3
  • 6
    • 0034925592 scopus 로고    scopus 로고
    • An HLA-directed molecular and bioinformatics approach identifies new HLA-A11 HIV-1 subtype E cytotoxic T lymphocyte epitopes in HIV-1-infected Thais
    • Bond, K. B., Sriwanthana, B., Hodge, T. W., De Groot, A. S., Mastro, T. D., Young, N. L., Promadej, N. et al., An HLA-directed molecular and bioinformatics approach identifies new HLA-A11 HIV-1 subtype E cytotoxic T lymphocyte epitopes in HIV-1-infected Thais. AIDS Res. Hum. Retroviruses 2001. 17: 703-717.
    • (2001) AIDS Res. Hum. Retroviruses , vol.17 , pp. 703-717
    • Bond, K.B.1    Sriwanthana, B.2    Hodge, T.W.3    De Groot, A.S.4    Mastro, T.D.5    Young, N.L.6    Promadej, N.7
  • 7
    • 0035879820 scopus 로고    scopus 로고
    • Definition of an optimal cytotoxic T lymphocyte epitope in the latently expressed Kaposi's sarcoma-associated herpesvirus kaposin protein
    • Brander, C., O'Connor, P., Suscovich, T., Jones, N. G., Lee, Y., Kedes, D., Ganem, D. et al., Definition of an optimal cytotoxic T lymphocyte epitope in the latently expressed Kaposi's sarcoma-associated herpesvirus kaposin protein. J. Infect. Dis. 2001. 184: 119-126.
    • (2001) J. Infect. Dis , vol.184 , pp. 119-126
    • Brander, C.1    O'Connor, P.2    Suscovich, T.3    Jones, N.G.4    Lee, Y.5    Kedes, D.6    Ganem, D.7
  • 8
    • 0029939093 scopus 로고    scopus 로고
    • Definition of the HLA-A29 peptide ligand motif allows prediction of potential T-cell epitopes from the retinal soluble antigen, a candidate autoantigen in birdshot retinopathy
    • Boisgerault, F., Khalil, L, Tieng, V., Connan, F., Tabary, T., Cohen, J. H., Choppin, J. et al., Definition of the HLA-A29 peptide ligand motif allows prediction of potential T-cell epitopes from the retinal soluble antigen, a candidate autoantigen in birdshot retinopathy. Proc. Natl. Acad. Sci. USA 1996. 93: 3466-3470.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 3466-3470
    • Boisgerault, F.1    Khalil, L.2    Tieng, V.3    Connan, F.4    Tabary, T.5    Cohen, J.H.6    Choppin, J.7
  • 9
    • 9144241614 scopus 로고    scopus 로고
    • Identification of novel CTL epitopes of CMV-pp65 presented by a variety of HLA alleles
    • Kondo, E., Akatsuka, Y., Kuzushima, K., Tsujimura, K., Asakura, S., Tajima, K., Kagami, Y. et al., Identification of novel CTL epitopes of CMV-pp65 presented by a variety of HLA alleles. Blood 2004. 103: 630-638.
    • (2004) Blood , vol.103 , pp. 630-638
    • Kondo, E.1    Akatsuka, Y.2    Kuzushima, K.3    Tsujimura, K.4    Asakura, S.5    Tajima, K.6    Kagami, Y.7
  • 11
    • 0033388724 scopus 로고    scopus 로고
    • Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism
    • Sette, A. and Sidney, J., Nine major HLA class I supertypes account for the vast preponderance of HLA-A and -B polymorphism. Immunogenetics 1999. 50: 201-212.
    • (1999) Immunogenetics , vol.50 , pp. 201-212
    • Sette, A.1    Sidney, J.2
  • 13
    • 23244463622 scopus 로고    scopus 로고
    • HLA-B63 presents HLA-B57/ B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load
    • Frahm, N., Adams, S., Kiepiela, P., Linde, C. H., Hewitt, H. S., Lichterfeld, M., Sango, K. et al., HLA-B63 presents HLA-B57/ B58-restricted cytotoxic T-lymphocyte epitopes and is associated with low human immunodeficiency virus load. J. Virol. 2005. 79: 10218-10225.
    • (2005) J. Virol , vol.79 , pp. 10218-10225
    • Frahm, N.1    Adams, S.2    Kiepiela, P.3    Linde, C.H.4    Hewitt, H.S.5    Lichterfeld, M.6    Sango, K.7
  • 14
    • 33749137810 scopus 로고    scopus 로고
    • Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype
    • Leslie, A., Price, D. A., Mkhize, P., Bishop, K., Rathod, A., Day, C., Crawford, H. et al., Differential selection pressure exerted on HIV by CTL targeting identical epitopes but restricted by distinct HLA alleles from the same HLA supertype. J. Immunol. 2006. 177: 4699-4708.
    • (2006) J. Immunol , vol.177 , pp. 4699-4708
    • Leslie, A.1    Price, D.A.2    Mkhize, P.3    Bishop, K.4    Rathod, A.5    Day, C.6    Crawford, H.7
  • 15
    • 0024796883 scopus 로고
    • Universally immunogenic T cell epitopes: Promiscuous binding to human MHC class II and promiscuous recognition by T cells
    • Panina-Bordignon, P., Tan, A., Termijtelen, A., Demotz, S., Corradin, G. and Lanzavecchia, A., Universally immunogenic T cell epitopes: promiscuous binding to human MHC class II and promiscuous recognition by T cells. Eur. J. Immunol. 1989. 19: 2237-2242.
    • (1989) Eur. J. Immunol , vol.19 , pp. 2237-2242
    • Panina-Bordignon, P.1    Tan, A.2    Termijtelen, A.3    Demotz, S.4    Corradin, G.5    Lanzavecchia, A.6
  • 16
    • 0026015286 scopus 로고
    • On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs
    • O'Sullivan, D., Arrhenius, T., Sidney, J., Del Guercio, M. F., Albertson, M., Wall, M., Oseroff, C. et al., On the interaction of promiscuous antigenic peptides with different DR alleles. Identification of common structural motifs. J. Immunol. 1991. 147: 2663-2669.
    • (1991) J. Immunol , vol.147 , pp. 2663-2669
    • O'Sullivan, D.1    Arrhenius, T.2    Sidney, J.3    Del Guercio, M.F.4    Albertson, M.5    Wall, M.6    Oseroff, C.7
  • 17
    • 4043176043 scopus 로고    scopus 로고
    • Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides
    • Kaufmann, D. E., Bailey, P. M., Sidney, J., Wagner, B., Norris, P. J., Johnston, M. N., Cosimi, L. A. et al., Comprehensive analysis of human immunodeficiency virus type 1-specific CD4 responses reveals marked immunodominance of gag and nef and the presence of broadly recognized peptides. J. Virol. 2004. 78: 4463-4477.
    • (2004) J. Virol , vol.78 , pp. 4463-4477
    • Kaufmann, D.E.1    Bailey, P.M.2    Sidney, J.3    Wagner, B.4    Norris, P.J.5    Johnston, M.N.6    Cosimi, L.A.7
  • 18
    • 0038176078 scopus 로고    scopus 로고
    • Identification of a naturally processed HLA-DR-restricted T-helper epitope in Epstein-Barr virus nuclear antigen type 1
    • Kruger, S., Schroers, R., Rooney, C. M., Galin, B. and Chen, S. Y., Identification of a naturally processed HLA-DR-restricted T-helper epitope in Epstein-Barr virus nuclear antigen type 1. J. Immunother. 2003. 26: 212-221.
    • (2003) J. Immunother , vol.26 , pp. 212-221
    • Kruger, S.1    Schroers, R.2    Rooney, C.M.3    Galin, B.4    Chen, S.Y.5
  • 19
    • 0034661982 scopus 로고    scopus 로고
    • HLA-DR-promiscuous T cell epitopes from Plasmodium falciparum pre-erythrocytic-stage antigens restricted by multiple HLA class II alleles
    • Doolan, D. L., Southwood, S., Chesnut, R., Appella, E., Gomez, E., Richards, A., Higashimoto, Y. I. et al., HLA-DR-promiscuous T cell epitopes from Plasmodium falciparum pre-erythrocytic-stage antigens restricted by multiple HLA class II alleles. J. Immunol. 2000. 165: 1123-1137.
    • (2000) J. Immunol , vol.165 , pp. 1123-1137
    • Doolan, D.L.1    Southwood, S.2    Chesnut, R.3    Appella, E.4    Gomez, E.5    Richards, A.6    Higashimoto, Y.I.7
  • 20
    • 0031751274 scopus 로고    scopus 로고
    • A new categorization of HLA DR alleles on a functional basis
    • Ou, D., Mitchell, L. A. and Tingle, A. J., A new categorization of HLA DR alleles on a functional basis. Hum. Immunol. 1998. 59: 665-676.
    • (1998) Hum. Immunol , vol.59 , pp. 665-676
    • Ou, D.1    Mitchell, L.A.2    Tingle, A.J.3
  • 21
    • 0037367652 scopus 로고    scopus 로고
    • The use of bioinformatics for identifying class II-restricted T-cell epitopes
    • Bian, H., Reidhaar-Olson, J. F. and Hammer, J., The use of bioinformatics for identifying class II-restricted T-cell epitopes. Methods 2003. 29: 299-309.
    • (2003) Methods , vol.29 , pp. 299-309
    • Bian, H.1    Reidhaar-Olson, J.F.2    Hammer, J.3
  • 22
    • 4644299613 scopus 로고    scopus 로고
    • Novel and promiscuous CTL epitopes in conserved regions of Gag targeted by individuals with early subtype C HIV type 1 infection from southern Africa
    • Masemola, A. M., Mashishi, T. N., Khoury, G., Bredell, H., Paximadis, M., Mathebula, T., Barkhan, D. et al., Novel and promiscuous CTL epitopes in conserved regions of Gag targeted by individuals with early subtype C HIV type 1 infection from southern Africa. J. Immunol. 2004. 173: 4607-4617.
    • (2004) J. Immunol , vol.173 , pp. 4607-4617
    • Masemola, A.M.1    Mashishi, T.N.2    Khoury, G.3    Bredell, H.4    Paximadis, M.5    Mathebula, T.6    Barkhan, D.7
  • 24
    • 0031571258 scopus 로고    scopus 로고
    • Degenerate and promiscuous recognition by cytotoxic T lymphocyte (CTL) of peptides presented by the MHC class I A3-like superfamily: Implications for vaccine development
    • Threlkeld, S. C., Wentworth, P., Kalams, S., Johnson, P., Wilkens, B. M., Ruble, D. J., Sidney, J. et al., Degenerate and promiscuous recognition by cytotoxic T lymphocyte (CTL) of peptides presented by the MHC class I A3-like superfamily: Implications for vaccine development. J. Immunol. 1997. 159: 1648-1657.
    • (1997) J. Immunol , vol.159 , pp. 1648-1657
    • Threlkeld, S.C.1    Wentworth, P.2    Kalams, S.3    Johnson, P.4    Wilkens, B.M.5    Ruble, D.J.6    Sidney, J.7
  • 25
    • 0029240323 scopus 로고
    • Overlap in the repertoires of peptides bound in vivo by a group of related class I HLA-B allotypes
    • Barber, L. D., Gillece-Castro, B., Percival, L., Li, X, Clayberger, C. and Parham, P., Overlap in the repertoires of peptides bound in vivo by a group of related class I HLA-B allotypes. Curr. Biol. 1995. 5: 179-190.
    • (1995) Curr. Biol , vol.5 , pp. 179-190
    • Barber, L.D.1    Gillece-Castro, B.2    Percival, L.3    Li, X.4    Clayberger, C.5    Parham, P.6
  • 26
    • 0041845058 scopus 로고    scopus 로고
    • Promiscuous CTL recognition of viral epitopes on multiple human leukocyte antigens: Biological validation of the proposed HLA A24 supertype
    • Burrows, S. R., Elkington, R. A., Miles, J. J., Green, K. J., Walker, S., Haryana, S. M., Moss, D. J. et al., Promiscuous CTL recognition of viral epitopes on multiple human leukocyte antigens: biological validation of the proposed HLA A24 supertype. J. Immunol. 2003. 171: 1407-1412.
    • (2003) J. Immunol , vol.171 , pp. 1407-1412
    • Burrows, S.R.1    Elkington, R.A.2    Miles, J.J.3    Green, K.J.4    Walker, S.5    Haryana, S.M.6    Moss, D.J.7
  • 27
    • 0036838933 scopus 로고    scopus 로고
    • Single T cell receptor-mediated recognition of an identical HIV-derived peptide presented by multiple HLA class I molecules
    • Ueno, T., Tomiyama, H. and Takiguchi, M., Single T cell receptor-mediated recognition of an identical HIV-derived peptide presented by multiple HLA class I molecules. J. Immunol. 2002. 169: 4961-4969.
    • (2002) J. Immunol , vol.169 , pp. 4961-4969
    • Ueno, T.1    Tomiyama, H.2    Takiguchi, M.3
  • 28
    • 0030747677 scopus 로고    scopus 로고
    • Degenerate cytotoxic T cell epitopes from P. falciparum restricted by multiple HLA-A and HLA-B supertype alleles
    • Doolan, D. L., Hoffman, S. L., Southwood, S., Wentworth, P. A., Sidney, J., Chesnut, R. W., Keogh, E. et al., Degenerate cytotoxic T cell epitopes from P. falciparum restricted by multiple HLA-A and HLA-B supertype alleles. Immunity 1997. 7: 97-112.
    • (1997) Immunity , vol.7 , pp. 97-112
    • Doolan, D.L.1    Hoffman, S.L.2    Southwood, S.3    Wentworth, P.A.4    Sidney, J.5    Chesnut, R.W.6    Keogh, E.7
  • 29
    • 0030811688 scopus 로고    scopus 로고
    • Human histocompatibility leukocyte antigen-binding supermotifs predict broadly cross-reactive cytotoxic T lymphocyte responses in patients with acute hepatitis
    • Bertoni, R., Sidney, J., Fowler, P., Chesnut, R. W., Chisari, F. V. and Sette, A., Human histocompatibility leukocyte antigen-binding supermotifs predict broadly cross-reactive cytotoxic T lymphocyte responses in patients with acute hepatitis. J. Clin. Invest. 1997 100: 503-513.
    • (1997) J. Clin. Invest , vol.100 , pp. 503-513
    • Bertoni, R.1    Sidney, J.2    Fowler, P.3    Chesnut, R.W.4    Chisari, F.V.5    Sette, A.6
  • 30
    • 0033555410 scopus 로고    scopus 로고
    • Identification of HLA-A3 and -B7-restricted CTL response to hepatitis C virus in patients with acute and chronic hepatitis C
    • Chang, K. M., Gruener, N. H., Southwood, S., Sidney, J., Pape, G. R., Chisari, F. V. and Sette, A., Identification of HLA-A3 and -B7-restricted CTL response to hepatitis C virus in patients with acute and chronic hepatitis C. J. Immunol. 1999. 162: 1156-1164.
    • (1999) J. Immunol , vol.162 , pp. 1156-1164
    • Chang, K.M.1    Gruener, N.H.2    Southwood, S.3    Sidney, J.4    Pape, G.R.5    Chisari, F.V.6    Sette, A.7
  • 31
    • 0002348697 scopus 로고    scopus 로고
    • The identification of optimal HIV derived CTL epitopes in diverse populations using HIV clade specific consensus
    • Korber, B. T, Brander, C, Haynes, B. F, Koup, R, Kuiken, C, Moore, J. P, Walker, B. D. and Watkins, D. I, Eds, Theoretical Biology and Biophysics Group: Los Alamos National Laboratory, Los Alamos
    • Brander, C. and Goulder, P. J. R., The identification of optimal HIV derived CTL epitopes in diverse populations using HIV clade specific consensus. In Korber, B. T., Brander, C., Haynes, B. F., Koup, R., Kuiken, C., Moore, J. P., Walker, B. D. and Watkins, D. I. (Eds.) HIV molecular immunology database. Theoretical Biology and Biophysics Group: Los Alamos National Laboratory, Los Alamos 2001, pp. 1-1-1-20.
    • (2001) HIV molecular immunology database
    • Brander, C.1    Goulder, P.J.R.2
  • 32
    • 25444498776 scopus 로고    scopus 로고
    • Simultaneous assessment of cytotoxic T lymphocyte responses against multiple viral infections by combined usage of optimal epitope matrices, anti- CD3 mAb T-cell expansion and "Recycle-Spot
    • Bihl, F. K., Loggi, E., Chisholm, J. V. 3rd, Hewitt, H. S., Henry, L. M., Linde, C., Suscovich, T. J. et al., Simultaneous assessment of cytotoxic T lymphocyte responses against multiple viral infections by combined usage of optimal epitope matrices, anti- CD3 mAb T-cell expansion and "Recycle-Spot". J. Transl. Med. 2005. 3: 20.
    • (2005) J. Transl. Med , vol.3 , pp. 20
    • Bihl, F.K.1    Loggi, E.2    Chisholm 3rd, J.V.3    Hewitt, H.S.4    Henry, L.M.5    Linde, C.6    Suscovich, T.J.7
  • 33
    • 0037302428 scopus 로고    scopus 로고
    • Comprehensive epitope analysis of HIV-1-specific T cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load
    • Addo, M. M., Yu, X. G., Rathod, A., Cohen, D., Eldridge, R. L., Strick, D., Johnston, M. N. et al., Comprehensive epitope analysis of HIV-1-specific T cell responses directed against the entire expressed HIV-1 genome demonstrate broadly directed responses, but no correlation to viral load. J. Virol. 2003. 77: 2081-2092.
    • (2003) J. Virol , vol.77 , pp. 2081-2092
    • Addo, M.M.1    Yu, X.G.2    Rathod, A.3    Cohen, D.4    Eldridge, R.L.5    Strick, D.6    Johnston, M.N.7
  • 34
    • 10744226946 scopus 로고    scopus 로고
    • Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities
    • Frahm, N., Korber, B. T., Adams, C. M., Szinger, J. J., Draenert, R., Addo, M. M., Feeney, M. E. et al., Consistent cytotoxic-T-lymphocyte targeting of immunodominant regions in human immunodeficiency virus across multiple ethnicities. J. Virol. 2004. 78: 2187-2200.
    • (2004) J. Virol , vol.78 , pp. 2187-2200
    • Frahm, N.1    Korber, B.T.2    Adams, C.M.3    Szinger, J.J.4    Draenert, R.5    Addo, M.M.6    Feeney, M.E.7
  • 35
    • 34548781492 scopus 로고    scopus 로고
    • Frahm, N., Goulder, P. J. R. and Brander, C., Total assessment of HIV-specific CTL responses: Epitope clustering, processing preferences, and the impact of HIV sequence heterogeneity. In Korber, B. T., Brander, C., Haynes, B. F., Koup, R., Kuiken, C., Moore, J. P., Walker, B. D. and Watkins, D. I. (Eds.) HIV molecular immunology Compendium. Los Alamos National Laboratory, Theoretical Biology and Biophysics. LA-UR 03-5816, Los Alamos 2002, pp. 1-1-1-22.
    • Frahm, N., Goulder, P. J. R. and Brander, C., Total assessment of HIV-specific CTL responses: Epitope clustering, processing preferences, and the impact of HIV sequence heterogeneity. In Korber, B. T., Brander, C., Haynes, B. F., Koup, R., Kuiken, C., Moore, J. P., Walker, B. D. and Watkins, D. I. (Eds.) HIV molecular immunology Compendium. Los Alamos National Laboratory, Theoretical Biology and Biophysics. LA-UR 03-5816, Los Alamos 2002, pp. 1-1-1-22.
  • 37
    • 33646019589 scopus 로고    scopus 로고
    • Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses
    • Bihl, F., Frahm, N., Di Giammarino, L., Sidney, J., John, M., Yusim, K., Woodberry, T. et al., Impact of HLA-B alleles, epitope binding affinity, functional avidity, and viral coinfection on the immunodominance of virus-specific CTL responses. J. Immunao. 2006. 176: 4094-4101.
    • (2006) J. Immunao , vol.176 , pp. 4094-4101
    • Bihl, F.1    Frahm, N.2    Di Giammarino, L.3    Sidney, J.4    John, M.5    Yusim, K.6    Woodberry, T.7
  • 40
    • 2242419092 scopus 로고    scopus 로고
    • Messaoudi, I., Guevara Patino, JA, Dyall, R., LeMaoult, J. and J., N.-Z., Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense. Science 2002. 298: 1797-1780.
    • Messaoudi, I., Guevara Patino, JA, Dyall, R., LeMaoult, J. and J., N.-Z., Direct link between mhc polymorphism, T cell avidity, and diversity in immune defense. Science 2002. 298: 1797-1780.
  • 42
    • 0032551668 scopus 로고    scopus 로고
    • Who is right? Or, how to judge the disagreement about HLA restriction of Nef peptides
    • Hunziker, I. P., Cerny, A. and Pichler, W. J., Who is right? Or, how to judge the disagreement about HLA restriction of Nef peptides. AIDS Res. Hum. Retroviruses 1998. 14: 921-924.
    • (1998) AIDS Res. Hum. Retroviruses , vol.14 , pp. 921-924
    • Hunziker, I.P.1    Cerny, A.2    Pichler, W.J.3
  • 44
    • 0027304399 scopus 로고    scopus 로고
    • Ruppert, J., Sidney, J., Celis, E., Kubo, R. T., Grey, H. M. and Sette, A., Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules. Cell 1993. 74: 929-937
    • Ruppert, J., Sidney, J., Celis, E., Kubo, R. T., Grey, H. M. and Sette, A., Prominent role of secondary anchor residues in peptide binding to HLA-A2.1 molecules. Cell 1993. 74: 929-937
  • 45
    • 0029897044 scopus 로고    scopus 로고
    • Practical, biochemical and evolutionary implications of the discovery of HLA class I supermotifs
    • Sidney, J., Grey, H. M., Kubo, R. T. and Sette, A., Practical, biochemical and evolutionary implications of the discovery of HLA class I supermotifs. Immunol. Today 1996. 17: 216-216.
    • (1996) Immunol. Today , vol.17 , pp. 216-216
    • Sidney, J.1    Grey, H.M.2    Kubo, R.T.3    Sette, A.4
  • 47
    • 27944510988 scopus 로고    scopus 로고
    • Identification of effector-memory CMV-specific T lymphocytes that kill CMV-infected target cells in an HLA-E-restricted fashion
    • Mazzarino, P., Pietra, G., Vacca, P., Falco, M., Colau, D., Coulie, P., Moretta, L. and Mingari, M. C., Identification of effector-memory CMV-specific T lymphocytes that kill CMV-infected target cells in an HLA-E-restricted fashion. Eur. J. Immunol. 2005. 35: 3240-3247.
    • (2005) Eur. J. Immunol , vol.35 , pp. 3240-3247
    • Mazzarino, P.1    Pietra, G.2    Vacca, P.3    Falco, M.4    Colau, D.5    Coulie, P.6    Moretta, L.7    Mingari, M.C.8
  • 48
    • 2542477867 scopus 로고    scopus 로고
    • HLA-E-restricted recognition of human cytormegalovirus by a subset of cytolytic T lymphocytes
    • Romagnani, C., Pietra, G., Falco, M., Mazzarino, P., Moretta, L. and Mingari, M. C., HLA-E-restricted recognition of human cytormegalovirus by a subset of cytolytic T lymphocytes. Hum. Immunol. 2004. 65: 437-445.
    • (2004) Hum. Immunol , vol.65 , pp. 437-445
    • Romagnani, C.1    Pietra, G.2    Falco, M.3    Mazzarino, P.4    Moretta, L.5    Mingari, M.C.6
  • 51
    • 0037165969 scopus 로고    scopus 로고
    • Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level
    • Moore, C. B., John, M., James, I. R., Christiansen, F. T., Witt, C. S. and Mallal, S. A., Evidence of HIV-1 adaptation to HLA-restricted immune responses at a population level. Science 2002. 296: 1439-1443.
    • (2002) Science , vol.296 , pp. 1439-1443
    • Moore, C.B.1    John, M.2    James, I.R.3    Christiansen, F.T.4    Witt, C.S.5    Mallal, S.A.6
  • 52
    • 20244373940 scopus 로고    scopus 로고
    • Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA
    • Leslie, A., Kavanagh, D., Honeyborne, L, Pfafferott, K., Edwards, C., Pillay, T., Hilton, L. et al., Transmission and accumulation of CTL escape variants drive negative associations between HIV polymorphisms and HLA. J. Exp. Med. 2005. 201: 891-902.
    • (2005) J. Exp. Med , vol.201 , pp. 891-902
    • Leslie, A.1    Kavanagh, D.2    Honeyborne, L.3    Pfafferott, K.4    Edwards, C.5    Pillay, T.6    Hilton, L.7
  • 53
    • 33947399689 scopus 로고    scopus 로고
    • Founder effects in population based assessment of HIV polymorphisms and HLA allele associations
    • Bhattacharya, T., Daniels, M., Heckerman, D., Foley, B., Frahm, N., Kadie, C., Carlson, J. et al., Founder effects in population based assessment of HIV polymorphisms and HLA allele associations. Science 2007. 315: 1583-1586.
    • (2007) Science , vol.315 , pp. 1583-1586
    • Bhattacharya, T.1    Daniels, M.2    Heckerman, D.3    Foley, B.4    Frahm, N.5    Kadie, C.6    Carlson, J.7
  • 55
    • 0035148309 scopus 로고    scopus 로고
    • Rapid definition of five novel HLA-A*3002-restricted human immunodeficiency virus-specific cytotoxic T-lymphocyte epitopes by ELISPOT and intracellular cytokine staining assays
    • Goulder, P. J., Addo, M. M., Altfeld, M. A., Rosenberg, E. S., Tang, Y., Govender, U., Mngqundaniso, N. et al., Rapid definition of five novel HLA-A*3002-restricted human immunodeficiency virus-specific cytotoxic T-lymphocyte epitopes by ELISPOT and intracellular cytokine staining assays. J. Virol. 2001. 75: 1339-1347.
    • (2001) J. Virol , vol.75 , pp. 1339-1347
    • Goulder, P.J.1    Addo, M.M.2    Altfeld, M.A.3    Rosenberg, E.S.4    Tang, Y.5    Govender, U.6    Mngqundaniso, N.7
  • 57
    • 0001677717 scopus 로고
    • Controlling the false discovery rate: A practical and powerful apporach to multiple testing
    • Benjamini, Y. and Hochberg, Y., Controlling the false discovery rate: A practical and powerful apporach to multiple testing. J. P, Star. Soc. B 1995. 57: 289-300.
    • (1995) J. P, Star. Soc. B , vol.57 , pp. 289-300
    • Benjamini, Y.1    Hochberg, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.