메뉴 건너뛰기




Volumn 242, Issue 2, 1998, Pages 414-424

Arginine residues in the C-terminus of HIV-1 Vpr are important for nuclear localization and cell cycle arrest

Author keywords

HIV 1; Nuclear localization and cell cycle; Vpr

Indexed keywords

AMINO ACID SEQUENCE; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL CYCLE; CELLULAR DISTRIBUTION; HUMAN IMMUNODEFICIENCY VIRUS 1; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION;

EID: 0032520546     PISSN: 00426822     EISSN: None     Source Type: Journal    
DOI: 10.1006/viro.1998.9028     Document Type: Article
Times cited : (57)

References (53)
  • 2
    • 0028297360 scopus 로고
    • Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: Mutational analysis of a primary HIV-1 isolate
    • Balliet J. W., Kolson D. L., Eiger G., Kim F. M., McGann K. A., Srinivasan A., Collman R. Distinct effects in primary macrophages and lymphocytes of the human immunodeficiency virus type 1 accessory genes vpr, vpu, and nef: Mutational analysis of a primary HIV-1 isolate. Virology. 200:1994;623-631.
    • (1994) Virology , vol.200 , pp. 623-631
    • Balliet, J.W.1    Kolson, D.L.2    Eiger, G.3    Kim, F.M.4    McGann, K.A.5    Srinivasan, A.6    Collman, R.7
  • 3
    • 0027299295 scopus 로고
    • Antisense phosphorothiolate oligodeoxynucleotides targeted to the vpr gene inhibit human immunodeficiency virus type 1 replication in primary human macrophages
    • Balotta C., Lusso P., Crowley R., Gallo R. C., Franchini G. Antisense phosphorothiolate oligodeoxynucleotides targeted to the vpr gene inhibit human immunodeficiency virus type 1 replication in primary human macrophages. J. Virol. 67:1993;4409-4414.
    • (1993) J. Virol. , vol.67 , pp. 4409-4414
    • Balotta, C.1    Lusso, P.2    Crowley, R.3    Gallo, R.C.4    Franchini, G.5
  • 4
    • 0030960351 scopus 로고    scopus 로고
    • Vpr of Simian immunodeficiency virus of African green monkeys is required for replication in macaque macrophages and lymphocytes
    • Campbell B. J., Hirsch V. M. Vpr of Simian immunodeficiency virus of African green monkeys is required for replication in macaque macrophages and lymphocytes. J. Virol. 71:1997;5593-5602.
    • (1997) J. Virol. , vol.71 , pp. 5593-5602
    • Campbell, B.J.1    Hirsch, V.M.2
  • 5
    • 0025295307 scopus 로고
    • Human immunodeficiency virus vpr product is a virion-associated regulatory protein
    • Cohen E. A., Dehni G., Sodroski J. G., Haseltine W. A. Human immunodeficiency virus vpr product is a virion-associated regulatory protein. J. Virol. 64:1990;3097-3099.
    • (1990) J. Virol. , vol.64 , pp. 3097-3099
    • Cohen, E.A.1    Dehni, G.2    Sodroski, J.G.3    Haseltine, W.A.4
  • 6
    • 0028842207 scopus 로고
    • Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes
    • Connor R. I., Chen B. K., Choe S., Landau N. R. Vpr is required for efficient replication of human immunodeficiency virus type-1 in mononuclear phagocytes. Virology. 206:1995;935-944.
    • (1995) Virology , vol.206 , pp. 935-944
    • Connor, R.I.1    Chen, B.K.2    Choe, S.3    Landau, N.R.4
  • 7
    • 0025072487 scopus 로고
    • Functions of the auxiliary gene products of the human immunodeficiency virus type-1
    • Cullen B. R., Green W. C. Functions of the auxiliary gene products of the human immunodeficiency virus type-1. Virology. 178:1990;1-5.
    • (1990) Virology , vol.178 , pp. 1-5
    • Cullen, B.R.1    Green, W.C.2
  • 8
    • 0024359636 scopus 로고
    • Viral protein R of human immunodeficiency virus types 1 and 2 is dispensable for replication and cytopathogenicity in lymphoid cells
    • Dedera D., Hu W., Vander Heyden N., Ratner L. Viral protein R of human immunodeficiency virus types 1 and 2 is dispensable for replication and cytopathogenicity in lymphoid cells. J. Virol. 63:1989;3205-3208.
    • (1989) J. Virol. , vol.63 , pp. 3205-3208
    • Dedera, D.1    Hu, W.2    Vander Heyden, N.3    Ratner, L.4
  • 9
    • 0028824894 scopus 로고
    • Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr
    • Di Marzio P., Choe S., Ebright M., Knoblauch R., Landau N. R. Mutational analysis of cell cycle arrest, nuclear localization and virion packaging of human immunodeficiency virus type 1 Vpr. J. Virol. 69:1995;7909-7916.
    • (1995) J. Virol. , vol.69 , pp. 7909-7916
    • Di Marzio, P.1    Choe, S.2    Ebright, M.3    Knoblauch, R.4    Landau, N.R.5
  • 10
    • 0030250588 scopus 로고    scopus 로고
    • HIV-1, Vpr and the cell cycle (Review)
    • Emerman M. HIV-1, Vpr and the cell cycle (Review). Curr. Biol. 6:1996;1096-1103.
    • (1996) Curr. Biol. , vol.6 , pp. 1096-1103
    • Emerman, M.1
  • 12
    • 0000233999 scopus 로고
    • Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase
    • Fuerst T. R., Niles E. G., Studier F. W., Moss B. Eukaryotic transient-expression system based on recombinant vaccinia virus that synthesizes bacteriophage T7 RNA polymerase. Proc. Natl. Acad. Sci. USA. 83:1986;8122-8126.
    • (1986) Proc. Natl. Acad. Sci. USA , vol.83 , pp. 8122-8126
    • Fuerst, T.R.1    Niles, E.G.2    Studier, F.W.3    Moss, B.4
  • 13
    • 0030065395 scopus 로고    scopus 로고
    • Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import
    • Gallay P., Stitt V., Mundy C., Oettinger M., Trono D. Role of the karyopherin pathway in human immunodeficiency virus type 1 nuclear import. J. Virol. 70:1996;1027-1032.
    • (1996) J. Virol. , vol.70 , pp. 1027-1032
    • Gallay, P.1    Stitt, V.2    Mundy, C.3    Oettinger, M.4    Trono, D.5
  • 15
    • 0026720075 scopus 로고
    • Tight control of gene expression in mammalian cells by tetracycline-responsive promoters
    • Gossen M., Bujard H. Tight control of gene expression in mammalian cells by tetracycline-responsive promoters. Proc. Natl. Acad. Sci. USA. 89:1992;5547-5551.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 5547-5551
    • Gossen, M.1    Bujard, H.2
  • 16
    • 0025017950 scopus 로고
    • The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages
    • Hattori N., Michaels F., Fargnoli K., Marcon L., Gallo R. C., Franchini G. The human immunodeficiency virus type 2 vpr gene is essential for productive infection of human macrophages. Proc. Natl. Acad. Sci. USA. 87:1990;8080-8084.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 8080-8084
    • Hattori, N.1    Michaels, F.2    Fargnoli, K.3    Marcon, L.4    Gallo, R.C.5    Franchini, G.6
  • 17
    • 0028853961 scopus 로고
    • Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G(2) phase of the cell cycle by inhibiting P34(Cdc2) activity
    • He J. L., Choe S., Walker R., Dimarzio P., Morgan D. O., Landau N. R. Human immunodeficiency virus type 1 viral protein R (Vpr) arrests cells in the G(2) phase of the cell cycle by inhibiting P34(Cdc2) activity. J. Virol. 69:1995;6705-6711.
    • (1995) J. Virol. , vol.69 , pp. 6705-6711
    • He, J.L.1    Choe, S.2    Walker, R.3    Dimarzio, P.4    Morgan, D.O.5    Landau, N.R.6
  • 20
    • 0029165291 scopus 로고
    • The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle
    • Jowett J. B., Planelles V., Poon B., Shah N. P., Chen M. L., Chen I. S. The human immunodeficiency virus type 1 vpr gene arrests infected T cells in the G2 + M phase of the cell cycle. J. Virol. 69:1995;6304-6313.
    • (1995) J. Virol. , vol.69 , pp. 6304-6313
    • Jowett, J.B.1    Planelles, V.2    Poon, B.3    Shah, N.P.4    Chen, M.L.5    Chen, I.S.6
  • 21
    • 0030009151 scopus 로고    scopus 로고
    • Protein stability influences human immunodeficiency virus type 2 Vpr virion incorporation and cell cycle effect
    • Kewalramani V. N., Park C. S., Gallombardo P. A., Emerman M. Protein stability influences human immunodeficiency virus type 2 Vpr virion incorporation and cell cycle effect. Virology. 218:1996;326-334.
    • (1996) Virology , vol.218 , pp. 326-334
    • Kewalramani, V.N.1    Park, C.S.2    Gallombardo, P.A.3    Emerman, M.4
  • 22
    • 0029925230 scopus 로고    scopus 로고
    • Consistent risk group-assisted differences in human immunodeficiency virus type 1 vpr, vpu, and V3 sequences despite independent evolution
    • Kuiken C. L., Cornelissen M. T., Zorgdrager F., Hartman S., Gibbs A. J., Goudsmit J. Consistent risk group-assisted differences in human immunodeficiency virus type 1 vpr, vpu, and V3 sequences despite independent evolution. J. Gen. Virol. 77:1996;783-792.
    • (1996) J. Gen. Virol. , vol.77 , pp. 783-792
    • Kuiken, C.L.1    Cornelissen, M.T.2    Zorgdrager, F.3    Hartman, S.4    Gibbs, A.J.5    Goudsmit, J.6
  • 24
    • 0027410459 scopus 로고
    • Induction of cell differentiation by human immunodeficiency virus 1 vpr
    • Levy D. N., Fernandes L. S., Williams W. V., Weiner D. B. Induction of cell differentiation by human immunodeficiency virus 1 vpr. Cell. 72:1993;541-550.
    • (1993) Cell , vol.72 , pp. 541-550
    • Levy, D.N.1    Fernandes, L.S.2    Williams, W.V.3    Weiner, D.B.4
  • 25
    • 0027376064 scopus 로고
    • Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions
    • Lu Y. L., Spearman P., Ratner L. Human immunodeficiency virus type 1 viral protein R localization in infected cells and virions. J. Virol. 67:1993;6542-6550.
    • (1993) J. Virol. , vol.67 , pp. 6542-6550
    • Lu, Y.L.1    Spearman, P.2    Ratner, L.3
  • 26
    • 0029880071 scopus 로고    scopus 로고
    • Extracellular addition of a domain of HIV-1 Vpr containing the amino acid sequence motif H(S/F)RIG causes cell membrane permeabilization and death
    • Macreadie I. G., Arunagiri C. K., Hewish D. R., White J. F., Azad A. A. Extracellular addition of a domain of HIV-1 Vpr containing the amino acid sequence motif H(S/F)RIG causes cell membrane permeabilization and death. Mol. Microbiol. 19:1996;1185-1192.
    • (1996) Mol. Microbiol. , vol.19 , pp. 1185-1192
    • MacReadie, I.G.1    Arunagiri, C.K.2    Hewish, D.R.3    White, J.F.4    Azad, A.A.5
  • 27
    • 0028944633 scopus 로고
    • A domain of human immunodeficiency virus type 1 Vpr containing repeated H(S/F)RIG amino acid motifs causes cell growth arrest and structural defects
    • Macreadie I. G., Castelli L. A., Hewish D. R., Kirkpatrick A., Ward A. C., Azad A. A. A domain of human immunodeficiency virus type 1 Vpr containing repeated H(S/F)RIG amino acid motifs causes cell growth arrest and structural defects. Proc. Natl. Acad. Sci. USA. 92:1995;2770-2774.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 2770-2774
    • MacReadie, I.G.1    Castelli, L.A.2    Hewish, D.R.3    Kirkpatrick, A.4    Ward, A.C.5    Azad, A.A.6
  • 28
    • 0029103269 scopus 로고
    • Role of the conserved dipeptide Gly75 and Cys76 on HIV-1 Vpr function
    • Mahalingam S., Collman R. G., Patel M., Monken C. E., Srinivasan A. Role of the conserved dipeptide Gly75 and Cys76 on HIV-1 Vpr function. Virology. 210:1995a;495-500.
    • (1995) Virology , vol.210 , pp. 495-500
    • Mahalingam, S.1    Collman, R.G.2    Patel, M.3    Monken, C.E.4    Srinivasan, A.5
  • 29
    • 0028988970 scopus 로고
    • Mutagenesis of the putative alpha-helical domain of the Vpr protein of human immunodeficiency virus type 1: Effect on stability and virion incorporation
    • Mahalingam S., Khan S. A., Murali R., Jabbar M. A., Monken C. E., Collman R. G., Srinivasan A. Mutagenesis of the putative alpha-helical domain of the Vpr protein of human immunodeficiency virus type 1: Effect on stability and virion incorporation. Proc. Natl. Acad. Sci. USA. 92:1995b;3794-3798.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3794-3798
    • Mahalingam, S.1    Khan, S.A.2    Murali, R.3    Jabbar, M.A.4    Monken, C.E.5    Collman, R.G.6    Srinivasan, A.7
  • 30
    • 0029620867 scopus 로고
    • The carboxy-terminal domain is essential for stability and not for virion incorporation of HIV-1 Vpr into virus particles
    • Mahalingam S., Patel M., Collman R. G., Srinivasan A. The carboxy-terminal domain is essential for stability and not for virion incorporation of HIV-1 Vpr into virus particles. Virology. 214:1995c;647-652.
    • (1995) Virology , vol.214 , pp. 647-652
    • Mahalingam, S.1    Patel, M.2    Collman, R.G.3    Srinivasan, A.4
  • 31
    • 0030586737 scopus 로고    scopus 로고
    • The mutation rate of human immunodeficiency virus type 1 is influenced by thevpr
    • Mansky L. M. The mutation rate of human immunodeficiency virus type 1 is influenced by thevpr. Virology. 222:1996;391-400.
    • (1996) Virology , vol.222 , pp. 391-400
    • Mansky, L.M.1
  • 32
    • 0029638755 scopus 로고
    • HIV gene arrests cell cycle (news)
    • McCarthy M. HIV gene arrests cell cycle (news). Lancet. 346:1995;960.
    • (1995) Lancet , vol.346 , pp. 960
    • McCarthy, M.1
  • 35
    • 0027429412 scopus 로고
    • Incorporation of Vpr into human immunodeficiency virus type 1 virions: Requirement for the p6 region of gag and mutational analysis
    • Paxton W., Connor R. I., Landau N. R. Incorporation of Vpr into human immunodeficiency virus type 1 virions: requirement for the p6 region of gag and mutational analysis. J. Virol. 67:1993;7229-7237.
    • (1993) J. Virol. , vol.67 , pp. 7229-7237
    • Paxton, W.1    Connor, R.I.2    Landau, N.R.3
  • 36
    • 9044243753 scopus 로고    scopus 로고
    • Vpr protein of human immunodeficiency virus type 1 forms cation-selective channels in planar lipid bilayers
    • Piller S. C., Ewart G. D., Premkumar A., Cox G. B., Gage P. W. Vpr protein of human immunodeficiency virus type 1 forms cation-selective channels in planar lipid bilayers. Proc. Natl. Acad. Sci. USA. 93:1996;111-115.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 111-115
    • Piller, S.C.1    Ewart, G.D.2    Premkumar, A.3    Cox, G.B.4    Gage, P.W.5
  • 37
    • 0029869861 scopus 로고    scopus 로고
    • Vpr-induced cell cycle arrest is conserved among primate lentiviruses
    • Planelles V., Jowett J. B., Li Q. X., Xie Y., Hahn B., Chen I. S. Vpr-induced cell cycle arrest is conserved among primate lentiviruses. J. Virol. 70:1996;2516-2524.
    • (1996) J. Virol. , vol.70 , pp. 2516-2524
    • Planelles, V.1    Jowett, J.B.2    Li, Q.X.3    Xie, Y.4    Hahn, B.5    Chen, I.S.6
  • 39
    • 0028801303 scopus 로고
    • Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B
    • Re F., Braaten D., Franke E. K., Luban J. Human immunodeficiency virus type 1 Vpr arrests the cell cycle in G2 by inhibiting the activation of p34cdc2-cyclin B. J. Virol. 69:1995;6859-6864.
    • (1995) J. Virol. , vol.69 , pp. 6859-6864
    • Re, F.1    Braaten, D.2    Franke, E.K.3    Luban, J.4
  • 40
    • 0028813107 scopus 로고
    • The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection
    • Rogel M. E., Wu L. I., Emerman M. The human immunodeficiency virus type 1 vpr gene prevents cell proliferation during chronic infection. J. Virol. 69:1995;882-888.
    • (1995) J. Virol. , vol.69 , pp. 882-888
    • Rogel, M.E.1    Wu, L.I.2    Emerman, M.3
  • 42
    • 0030958826 scopus 로고    scopus 로고
    • Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrest
    • Selig L., Benichou S., Rogel M. E., Wu L. I., Vodicka M. A., Sire J., Benarous R., Emerman M. Uracil DNA glycosylase specifically interacts with Vpr of both human immunodeficiency virus type 1 and simian immunodeficiency virus of sooty mangabeys, but binding does not correlate with cell cycle arrest. J. Virol. 71:1997;4842-4846.
    • (1997) J. Virol. , vol.71 , pp. 4842-4846
    • Selig, L.1    Benichou, S.2    Rogel, M.E.3    Wu, L.I.4    Vodicka, M.A.5    Sire, J.6    Benarous, R.7    Emerman, M.8
  • 43
    • 0030960059 scopus 로고    scopus 로고
    • Conservation and host specificity of Vpr-mediated cell cycle arrest suggest a fundamental role in primate lentivirus evolution and biology
    • Stivahtis G. L., Soares M. A., Vodicka M. A., Hahn B. H., Emerman M. Conservation and host specificity of Vpr-mediated cell cycle arrest suggest a fundamental role in primate lentivirus evolution and biology. J. Virol. 71:1997;4331-4338.
    • (1997) J. Virol. , vol.71 , pp. 4331-4338
    • Stivahtis, G.L.1    Soares, M.A.2    Vodicka, M.A.3    Hahn, B.H.4    Emerman, M.5
  • 44
    • 0028116642 scopus 로고
    • Molecular biology of the human immunodeficiency virus accessory proteins
    • Subbramanian R. A., Cohen E. A. Molecular biology of the human immunodeficiency virus accessory proteins. J. Virol. 68:1994;6831-6835.
    • (1994) J. Virol. , vol.68 , pp. 6831-6835
    • Subbramanian, R.A.1    Cohen, E.A.2
  • 45
    • 0030247883 scopus 로고    scopus 로고
    • Gene defects clustered at the C-terminus of the vpr gene of HIV-1 in long-term nonprogressing mother and child pair: In vivo evolution of vpr quasispecies in blood and plasma
    • Wang B., Ge Y. C., Palasanthiran P., Xiang S. H., Ziegler J., Dwyer D. E., Randle C., Dowton D., Cunningham A., Saksena N. K. Gene defects clustered at the C-terminus of the vpr gene of HIV-1 in long-term nonprogressing mother and child pair: In vivo evolution of vpr quasispecies in blood and plasma. Virology. 223:1996;224-232.
    • (1996) Virology , vol.223 , pp. 224-232
    • Wang, B.1    Ge, Y.C.2    Palasanthiran, P.3    Xiang, S.H.4    Ziegler, J.5    Dwyer, D.E.6    Randle, C.7    Dowton, D.8    Cunningham, A.9    Saksena, N.K.10
  • 46
    • 0027978293 scopus 로고
    • Particle assembly and Vpr expression in human immunodeficiency virus type 1-infected cells demonstrated by immunoelectron microscopy
    • Wang J. J., Lu Y., Ratner L. Particle assembly and Vpr expression in human immunodeficiency virus type 1-infected cells demonstrated by immunoelectron microscopy. J. Gen. Virol. 75:1994;2607-2614.
    • (1994) J. Gen. Virol. , vol.75 , pp. 2607-2614
    • Wang, J.J.1    Lu, Y.2    Ratner, L.3
  • 47
    • 0026356172 scopus 로고
    • Identification of a determinant within the human immunodeficiency virus 1 surface envelope glycoprotein critical for productive infection of primary monocytes
    • Westervelt P., Gendelman H. E., Ratner L. Identification of a determinant within the human immunodeficiency virus 1 surface envelope glycoprotein critical for productive infection of primary monocytes. Proc. Natl. Acad. Sci. USA. 88:1991;3097-3101.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 3097-3101
    • Westervelt, P.1    Gendelman, H.E.2    Ratner, L.3
  • 49
    • 0028840657 scopus 로고
    • Mutagenic analysis of human immunodeficiency virus type 1 Vpr: Role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation
    • Yao X. J., Subbramanian R. A., Rougeau N., Boisvert F., Bergeron D., Cohen E. A. Mutagenic analysis of human immunodeficiency virus type 1 Vpr: Role of a predicted N-terminal alpha-helical structure in Vpr nuclear localization and virion incorporation. J. Virol. 69:1995;7031-7044.
    • (1995) J. Virol. , vol.69 , pp. 7031-7044
    • Yao, X.J.1    Subbramanian, R.A.2    Rougeau, N.3    Boisvert, F.4    Bergeron, D.5    Cohen, E.A.6
  • 50
    • 0031592602 scopus 로고    scopus 로고
    • Cell cycle inhibitory effects of HIV and SIV Vpr and Vpx in the yeast Schizosaccharomyces pombe
    • Zhang C., Rasmussen C., Chang L. J. Cell cycle inhibitory effects of HIV and SIV Vpr and Vpx in the yeast Schizosaccharomyces pombe. Virology. 230:1997;103-112.
    • (1997) Virology , vol.230 , pp. 103-112
    • Zhang, C.1    Rasmussen, C.2    Chang, L.J.3
  • 51
    • 0028318421 scopus 로고
    • Biochemical mechanism of HIV-I Vpr function. Specific interaction with a cellular protein
    • Zhao L. J., Mukherjee S., Narayan O. Biochemical mechanism of HIV-I Vpr function. Specific interaction with a cellular protein. J. Biol. Chem. 269:1994a;15577-15582.
    • (1994) J. Biol. Chem. , vol.269 , pp. 15577-15582
    • Zhao, L.J.1    Mukherjee, S.2    Narayan, O.3
  • 52
    • 0028600072 scopus 로고
    • Biochemical mechanism of HIV-1 Vpr function. Oligomerization mediated by the N-terminal domain
    • Zhao L. J., Wang L., Mukherjee S., Narayan O. Biochemical mechanism of HIV-1 Vpr function. Oligomerization mediated by the N-terminal domain. J. Biol. Chem. 269:1994b;32131-32137.
    • (1994) J. Biol. Chem. , vol.269 , pp. 32131-32137
    • Zhao, L.J.1    Wang, L.2    Mukherjee, S.3    Narayan, O.4
  • 53
    • 0029843983 scopus 로고    scopus 로고
    • Effect of human immunodeficiency virus type 1 protein R (vpr) gene expression on basic cellular function of fission yeast Schizosaccharomyces pombe
    • Zhao Y., Cao J., O'Gorman M. R., Yu M., Yogev R. Effect of human immunodeficiency virus type 1 protein R (vpr) gene expression on basic cellular function of fission yeast Schizosaccharomyces pombe. J. Virol. 70:1996;5821-5826.
    • (1996) J. Virol. , vol.70 , pp. 5821-5826
    • Zhao, Y.1    Cao, J.2    O'Gorman, M.R.3    Yu, M.4    Yogev, R.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.