Pael-R transgenic mice crossed with parkin deficient mice displayed progressive and selective catecholaminergic neuronal loss

Journal of Neurochemistry

Volumn 107, Issue 1, 2008, Pages 171-185

  Wang, Hua Qin ^a,b,c   Imai, Yuzuru ^d   Inoue, Haruhisa ^a,b,e   Kataoka, Ayane ^b   Iita, Sachiko ^b   Nukina, Nobuyuki ^b   Takahashi, Ryosuke ^a,b,e  

^a KYOTO UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^b RIKEN BRAIN SCIENCE INSTITUTE   (Japan)

^c CHINA MEDICAL UNIVERSITY   (China)

^d TOHOKU UNIVERSITY   (Japan)

^e JAPAN SCIENCE AND TECHNOLOGY AGENCY   (Japan)

Author keywords

Dopaminergic neuron; Endoplasmic reticulam stress; Mitochondrial complex I; Pael R; Parkin

Indexed keywords

CASPASE 12; DOPAMINE; ENDOTHELIN RECEPTOR; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; MITOGEN ACTIVATED PROTEIN KINASE P38; PARKIN; PARKIN ASSOCIATED ENDOTHELIN RECEPTOR LIKE RECEPTOR; PLATELET DERIVED GROWTH FACTOR; PROTEIN SUBUNIT; REDUCED NICOTINAMIDE ADENINE DINUCLEOTIDE DEHYDROGENASE (UBIQUINONE); UNCLASSIFIED DRUG;

ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; AUTOSOMAL RECESSIVE DISORDER; CATECHOLAMINE NERVE CELL; CELL LOSS; CONTROLLED STUDY; DOPAMINERGIC NERVE CELL; ENDOPLASMIC RETICULUM STRESS; ENZYME ACTIVITY; HUMAN; MITOCHONDRION; MOUSE; NERVE DEGENERATION; NONHUMAN; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN FOLDING; PROTEIN FUNCTION; UPREGULATION;

ANIMALS; BRAIN; CATECHOLAMINES; CELL DEATH; CHRONIC DISEASE; DISEASE MODELS, ANIMAL; DISEASE PROGRESSION; DOPAMINE; ELECTRON TRANSPORT COMPLEX I; HUMANS; MICE; MICE, KNOCKOUT; MICE, TRANSGENIC; NERVE DEGENERATION; NEURONS; NOREPINEPHRINE; OXIDATIVE STRESS; PARKINSONIAN DISORDERS; PROTEIN FOLDING; RECEPTORS, G-PROTEIN-COUPLED; SUBSTANTIA NIGRA; UBIQUITIN-PROTEIN LIGASES;

ANIMALIA; MUS; MUS MUSCULUS;

EID: 51849134081     PISSN: 00223042     EISSN: 14714159     Source Type: Journal    
DOI: 10.1111/j.1471-4159.2008.05607.x     Document Type: Article

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