Comparison of growth inhibition profiles and mechanisms of apoptosis induction in human colon cancer cell lines by isothiocyanates and indoles from Brassicaceae

Mutation Research - Fundamental and Molecular Mechanisms of Mutagenesis

Volumn 599, Issue 1-2, 2006, Pages 76-87

  Pappa, Gerlinde ^a   Lichtenberg, Maike ^a   Iori, Renato ^b   Barillari, Jessica ^b   Bartsch, Helmut ^a   Gerhäuser, Clarissa ^a  

^a GERMAN CANCER RESEARCH CENTER DKFZ   (Germany)

^b ISTITUTO NAZIONALE DELLA NUTRIZIONE   (Italy)

Author keywords

Apoptosis; Bcl 2 family proteins; Caspases; Colon cancer; Indoles; Isothiocyanates

Indexed keywords

3,3' DIINDOLYLMETHANE; ANTINEOPLASTIC AGENT; BETA PHENETHYLISOTHIOCYANATE; CASPASE 7; CASPASE 9; GLUCONASTURTIIN; GLUCORAPHANIN; GLUCOSINOLATE; INDOLE 3 CARBINOLE; INDOLE DERIVATIVE; ISOTHIOCYANIC ACID DERIVATIVE; NICOTINAMIDE ADENINE DINUCLEOTIDE ADENOSINE DIPHOSPHATE RIBOSYLTRANSFERASE; PROTEIN BAK; PROTEIN BAX; PROTEIN BCL 2; PROTEIN BCL XL; PROTEIN P53; SULFORAPHANE; SULFORHODAMINE B; THIOGLUCOSIDASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; BRASSICACEAE; CANCER CELL CULTURE; CANCER INHIBITION; CELL PROLIFERATION; COLON CANCER; CONCENTRATION RESPONSE; CONTROLLED STUDY; CYTOSTASIS; CYTOTOXICITY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; ENZYME ACTIVATION; HUMAN; HUMAN CELL; IMMUNOBLOTTING; MITOCHONDRION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FAMILY; SIGNAL TRANSDUCTION; STAINING; WESTERN BLOTTING;

ANTINEOPLASTIC AGENTS, PHYTOGENIC; APOPTOSIS; BRASSICACEAE; CASPASE 7; CASPASE 9; CASPASES; CELL LINE, TUMOR; CELL PROLIFERATION; COLONIC NEOPLASMS; GENE EXPRESSION PROFILING; GENES, P53; HUMANS; INDOLES; ISOTHIOCYANATES; PHYTOTHERAPY; POLY(ADP-RIBOSE) POLYMERASES; PROTO-ONCOGENE PROTEINS C-BCL-2; THIOCYANATES;

BRASSICACEAE;

EID: 33745875948     PISSN: 00275107     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mrfmmm.2006.01.007     Document Type: Article

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