The biphasic role of the hypoxia-inducible factor prolyl-4-hydroxylase, PHD2, in modulating tumor-forming potential

Molecular Cancer Research

Volumn 6, Issue 5, 2008, Pages 829-842

  Lee, KangAe ^a,b   Lynd, Jeremy D ^a,b   O'Reilly, Sandra ^b   Kiupel, Matti ^b   McCormick, J Justin ^a,b,c   LaPres, John J ^a,b  

^a Michigan State University   (United States)

^b MICHIGAN STATE UNIVERSITY   (United States)

^c NONE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ENDOTHELIAL CELL GROWTH FACTOR; HYPOXIA INDUCIBLE FACTOR 1; ISOPROTEIN; PROCOLLAGEN PROLINE 2 OXOGLUTARATE 4 DIOXYGENASE; PROLYL 4 HYDROXYLASE PHD2; UNCLASSIFIED DRUG; EGLN1 PROTEIN, HUMAN; HIF1A PROTEIN, HUMAN; HYPOXIA INDUCIBLE FACTOR 1ALPHA; MESSENGER RNA;

ARTICLE; CARCINOGENESIS; CELL STRAIN; CELL TRANSFORMATION; CONTROLLED STUDY; ENZYME MECHANISM; GLYCOLYSIS; HUMAN; HUMAN CELL; HYPOXIA; MALIGNANT TRANSFORMATION; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; ANOXIA; CELL DEATH; CELL LINE; CELL LINEAGE; CHEMISTRY; DOSE RESPONSE; FIBROBLAST; GENE EXPRESSION REGULATION; METABOLISM; NEOPLASM; PHYSIOLOGY; RNA INTERFERENCE;

ANOXIA; CELL DEATH; CELL LINE; CELL LINEAGE; DOSE-RESPONSE RELATIONSHIP, DRUG; FIBROBLASTS; GENE EXPRESSION REGULATION, NEOPLASTIC; GLYCOLYSIS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; NEOPLASMS; PROCOLLAGEN-PROLINE DIOXYGENASE; PROTEIN ISOFORMS; RNA INTERFERENCE; RNA, MESSENGER;

EID: 51049097730     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: 10.1158/1541-7786.MCR-07-2113     Document Type: Article

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