-
1
-
-
23844438197
-
Adenovirus type 5 E4orf3 protein targets the Mre11 complex to cytoplasmic aggresomes
-
Araujo, F. D., T. H. Stracker, C. T. Carson, D. V. Lee, and M. D. Weitzman. 2005. Adenovirus type 5 E4orf3 protein targets the Mre11 complex to cytoplasmic aggresomes. J. Virol. 79:11382-11391.
-
(2005)
J. Virol
, vol.79
, pp. 11382-11391
-
-
Araujo, F.D.1
Stracker, T.H.2
Carson, C.T.3
Lee, D.V.4
Weitzman, M.D.5
-
2
-
-
34250894884
-
Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation
-
Baker, A., K. J. Rohleder, L. A. Hanakahi, and G. Ketner. 2007. Adenovirus E4 34k and E1b 55k oncoproteins target host DNA ligase IV for proteasomal degradation. J. Virol. 81:7034-7040.
-
(2007)
J. Virol
, vol.81
, pp. 7034-7040
-
-
Baker, A.1
Rohleder, K.J.2
Hanakahi, L.A.3
Ketner, G.4
-
3
-
-
33847737716
-
DNA damage checkpoints: From initiation to recovery or adaptation
-
Bartek, J., and J. Lukas. 2007. DNA damage checkpoints: from initiation to recovery or adaptation. Curr. Opin. Cell Biol. 19:238-245.
-
(2007)
Curr. Opin. Cell Biol
, vol.19
, pp. 238-245
-
-
Bartek, J.1
Lukas, J.2
-
4
-
-
40149099594
-
Control of mRNA export by adenovirus E4orf6 and E1B55K proteins during productive infection requires the E4orf6 ubiquitin ligase activity
-
Blanchette, P., K. Kindsmuller, P. Groitl, F. Dallaire, T. Speiseder, P. E. Branton, and T. Dobner. 2008. Control of mRNA export by adenovirus E4orf6 and E1B55K proteins during productive infection requires the E4orf6 ubiquitin ligase activity. J. Virol. 82:2642-2651.
-
(2008)
J. Virol
, vol.82
, pp. 2642-2651
-
-
Blanchette, P.1
Kindsmuller, K.2
Groitl, P.3
Dallaire, F.4
Speiseder, T.5
Branton, P.E.6
Dobner, T.7
-
5
-
-
34547686372
-
The multiple roles of the Mre11 complex for meiotic recombination
-
Borde, V. 2007. The multiple roles of the Mre11 complex for meiotic recombination. Chromosome Res. 15:551-563.
-
(2007)
Chromosome Res
, vol.15
, pp. 551-563
-
-
Borde, V.1
-
6
-
-
0033604299
-
Adenovirus E4 34k and E4 11k inhibit double strand break repair and are physically associated with the cellular DNA-dependent protein kinase
-
Boyer, J., K. Rohleder, and G. Ketner. 1999. Adenovirus E4 34k and E4 11k inhibit double strand break repair and are physically associated with the cellular DNA-dependent protein kinase. Virology 263:307-312.
-
(1999)
Virology
, vol.263
, pp. 307-312
-
-
Boyer, J.1
Rohleder, K.2
Ketner, G.3
-
7
-
-
0025037997
-
Interaction of adenoviral E4 and E1b products in late gene expression
-
Bridge, E., and G. Ketner. 1990. Interaction of adenoviral E4 and E1b products in late gene expression. Virology 174:345-353.
-
(1990)
Virology
, vol.174
, pp. 345-353
-
-
Bridge, E.1
Ketner, G.2
-
8
-
-
0024571586
-
Redundant control of adenovirus late gene expression by early region 4
-
Bridge, E., and G. Ketner. 1989. Redundant control of adenovirus late gene expression by early region 4. J. Virol. 63:631-638.
-
(1989)
J. Virol
, vol.63
, pp. 631-638
-
-
Bridge, E.1
Ketner, G.2
-
10
-
-
4544355447
-
Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm
-
Cerosaletti, K., and P. Concannon. 2004. Independent roles for nibrin and Mre11-Rad50 in the activation and function of Atm. J. Biol. Chem. 279:38813-38819.
-
(2004)
J. Biol. Chem
, vol.279
, pp. 38813-38819
-
-
Cerosaletti, K.1
Concannon, P.2
-
11
-
-
33644538562
-
Active role for nibrin in the kinetics of Atm activation
-
Cerosaletti, K., J. Wright, and P. Concannon. 2006. Active role for nibrin in the kinetics of Atm activation. Mol. Cell. Biol. 26:1691-1699.
-
(2006)
Mol. Cell. Biol
, vol.26
, pp. 1691-1699
-
-
Cerosaletti, K.1
Wright, J.2
Concannon, P.3
-
12
-
-
0037821657
-
Nibrin forkhead-associated domain and breast cancer C-terminal domain are both required for nuclear focus formation and phosphorylation
-
Cerosaletti, K. M., and P. Concannon. 2003. Nibrin forkhead-associated domain and breast cancer C-terminal domain are both required for nuclear focus formation and phosphorylation. J. Biol. Chem. 278:21944-21951.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 21944-21951
-
-
Cerosaletti, K.M.1
Concannon, P.2
-
13
-
-
0034066847
-
Retroviral expression of the NBS1 gene in cultured Nijmegen breakage syndrome cells restores normal radiation sensitivity and nuclear focus formation
-
Cerosaletti, K. M., A. Desai-Mehta, T. C. Yeo, M. Kraakman-Van Der Zwet, M. Z. Zdzienicka, and P. Concannon. 2000. Retroviral expression of the NBS1 gene in cultured Nijmegen breakage syndrome cells restores normal radiation sensitivity and nuclear focus formation. Mutagenesis 15:281-286.
-
(2000)
Mutagenesis
, vol.15
, pp. 281-286
-
-
Cerosaletti, K.M.1
Desai-Mehta, A.2
Yeo, T.C.3
Kraakman-Van Der Zwet, M.4
Zdzienicka, M.Z.5
Concannon, P.6
-
14
-
-
0242268123
-
Adenovirus E4-34kDa requires active proteasomes to promote late gene expression
-
Corbin-Lickfett, K. A., and E. Bridge. 2003. Adenovirus E4-34kDa requires active proteasomes to promote late gene expression. Virology 315:234-244.
-
(2003)
Virology
, vol.315
, pp. 234-244
-
-
Corbin-Lickfett, K.A.1
Bridge, E.2
-
15
-
-
0036276388
-
The Mre11 complex: At the crossroads of DNA repair and checkpoint signalling
-
D'Amours, D., and S. P. Jackson. 2002. The Mre11 complex: at the crossroads of DNA repair and checkpoint signalling. Nat. Rev. Mol. Cell. Biol. 3:317-327.
-
(2002)
Nat. Rev. Mol. Cell. Biol
, vol.3
, pp. 317-327
-
-
D'Amours, D.1
Jackson, S.P.2
-
16
-
-
0034997651
-
Distinct functional domains of nibrin mediate Mre11 binding, focus formation, and nuclear localization
-
Desai-Mehta, A., K. M. Cerosaletti, and P. Concannon. 2001. Distinct functional domains of nibrin mediate Mre11 binding, focus formation, and nuclear localization. Mol. Cell. Biol. 21:2184-2191.
-
(2001)
Mol. Cell. Biol
, vol.21
, pp. 2184-2191
-
-
Desai-Mehta, A.1
Cerosaletti, K.M.2
Concannon, P.3
-
17
-
-
22144462810
-
Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models
-
Difilippantonio, S., A. Celeste, O. Fernandez-Capetillo, H. T. Chen, B. Reina San Martin, F. Van Laethem, Y. P. Yang, G. V. Petukhova, M. Eckhaus, L. Feigenbaum, K. Manova, M. Kruhlak, R. D. Camerini-Otero, S. Sharan, M. Nussenzweig, and A. Nussenzweig. 2005. Role of Nbs1 in the activation of the Atm kinase revealed in humanized mouse models. Nat. Cell Biol. 7:675-685.
-
(2005)
Nat. Cell Biol
, vol.7
, pp. 675-685
-
-
Difilippantonio, S.1
Celeste, A.2
Fernandez-Capetillo, O.3
Chen, H.T.4
Reina San Martin, B.5
Van Laethem, F.6
Yang, Y.P.7
Petukhova, G.V.8
Eckhaus, M.9
Feigenbaum, L.10
Manova, K.11
Kruhlak, M.12
Camerini-Otero, R.D.13
Sharan, S.14
Nussenzweig, M.15
Nussenzweig, A.16
-
18
-
-
34249048548
-
Distinct domains in Nbs1 regulate irradiation-induced checkpoints and apoptosis
-
Difilippantonio, S., A. Celeste, M. J. Kruhlak, Y. Lee, M. J. Difilippantonio, L. Feigenbaum, S. P. Jackson, P. J. McKinnon, and A. Nussenzweig. 2007. Distinct domains in Nbs1 regulate irradiation-induced checkpoints and apoptosis. J. Exp. Med. 204:1003-1011.
-
(2007)
J. Exp. Med
, vol.204
, pp. 1003-1011
-
-
Difilippantonio, S.1
Celeste, A.2
Kruhlak, M.J.3
Lee, Y.4
Difilippantonio, M.J.5
Feigenbaum, L.6
Jackson, S.P.7
McKinnon, P.J.8
Nussenzweig, A.9
-
19
-
-
0037404513
-
-
Evans, J. D., and P. Hearing. 2003. Distinct roles of the Adenovirus E4 ORF3 protein in viral DNA replication and inhibition of genome concatenation. J. Virol. 77:5295-5304.
-
Evans, J. D., and P. Hearing. 2003. Distinct roles of the Adenovirus E4 ORF3 protein in viral DNA replication and inhibition of genome concatenation. J. Virol. 77:5295-5304.
-
-
-
-
20
-
-
18144401244
-
-
Evans, J. D., and P. Hearing. 2005. Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication. J. Virol. 79:6207-6215.
-
Evans, J. D., and P. Hearing. 2005. Relocalization of the Mre11-Rad50-Nbs1 complex by the adenovirus E4 ORF3 protein is required for viral replication. J. Virol. 79:6207-6215.
-
-
-
-
21
-
-
15844394846
-
Conserved modes of recruitment of ATM, ATR, and DNA-PKcs to sites of DNA damage
-
Falck, J., J. Coates, and S. P. Jackson. 2005. Conserved modes of recruitment of ATM, ATR, and DNA-PKcs to sites of DNA damage. Nature 434:605-611.
-
(2005)
Nature
, vol.434
, pp. 605-611
-
-
Falck, J.1
Coates, J.2
Jackson, S.P.3
-
22
-
-
0034106722
-
ATM-dependent phosphorylation of nibrin in response to radiation exposure
-
Gatei, M., D. Young, K. M. Cerosaletti, A. Desai-Mehta, K. Spring, S. Kozlov, M. F. Lavin, R. A. Gatti, P. Concannon, and K. Khanna. 2000. ATM-dependent phosphorylation of nibrin in response to radiation exposure. Nat. Genet. 25:115-119.
-
(2000)
Nat. Genet
, vol.25
, pp. 115-119
-
-
Gatei, M.1
Young, D.2
Cerosaletti, K.M.3
Desai-Mehta, A.4
Spring, K.5
Kozlov, S.6
Lavin, M.F.7
Gatti, R.A.8
Concannon, P.9
Khanna, K.10
-
23
-
-
0033621110
-
Role of the type 5 adenovirus gene encoding the early region 1B 55-kDa protein in pulmonary pathogenesis
-
Ginsberg, H. S., L. L. Moldawer, and G. A. Prince. 1999. Role of the type 5 adenovirus gene encoding the early region 1B 55-kDa protein in pulmonary pathogenesis. Proc. Natl. Acad. Sci. USA 96:10409-10411.
-
(1999)
Proc. Natl. Acad. Sci. USA
, vol.96
, pp. 10409-10411
-
-
Ginsberg, H.S.1
Moldawer, L.L.2
Prince, G.A.3
-
24
-
-
0022381043
-
Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff
-
Halbert, D. N., J. R. Cutt, and T. Shenk. 1985. Adenovirus early region 4 encodes functions required for efficient DNA replication, late gene expression, and host cell shutoff. J. Virol. 56:250-257.
-
(1985)
J. Virol
, vol.56
, pp. 250-257
-
-
Halbert, D.N.1
Cutt, J.R.2
Shenk, T.3
-
25
-
-
0024344731
-
-
Huang, M.-H., and P. Hearing. 1989. Adenovirus early region 4 encodes two gene products with redundant effects in lytic infection. J. Virol. 63:2605-2615.
-
Huang, M.-H., and P. Hearing. 1989. Adenovirus early region 4 encodes two gene products with redundant effects in lytic infection. J. Virol. 63:2605-2615.
-
-
-
-
26
-
-
27644526591
-
Genome concatenation contributes to the late gene expression defect of an adenovirus E4 mutant
-
Jayaram, S., and E. Bridge. 2005. Genome concatenation contributes to the late gene expression defect of an adenovirus E4 mutant. Virology 342:286-296.
-
(2005)
Virology
, vol.342
, pp. 286-296
-
-
Jayaram, S.1
Bridge, E.2
-
27
-
-
30344463835
-
ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks
-
Jazayeri, A., J. Falck, C. Lukas, J. Bartek, G. C. Smith, J. Lukas, and S. P. Jackson. 2006. ATM- and cell cycle-dependent regulation of ATR in response to DNA double-strand breaks. Nat. Cell Biol. 8:37-45.
-
(2006)
Nat. Cell Biol
, vol.8
, pp. 37-45
-
-
Jazayeri, A.1
Falck, J.2
Lukas, C.3
Bartek, J.4
Smith, G.C.5
Lukas, J.6
Jackson, S.P.7
-
28
-
-
9244251125
-
Cell-cycle checkpoints and cancer
-
Kastan, M. B., and J. Bartek. 2004. Cell-cycle checkpoints and cancer. Nature 432:316-323.
-
(2004)
Nature
, vol.432
, pp. 316-323
-
-
Kastan, M.B.1
Bartek, J.2
-
29
-
-
0034576494
-
The many substrates and functions of ATM
-
Kastan, M. B., and D. S. Lim. 2000. The many substrates and functions of ATM. Nat. Rev. Mol. Cell. Biol. 1:179-186.
-
(2000)
Nat. Rev. Mol. Cell. Biol
, vol.1
, pp. 179-186
-
-
Kastan, M.B.1
Lim, D.S.2
-
30
-
-
13844256190
-
Molecular mechanism of the recruitment of NBS1/hMRE11/hRAD50 complex to DNA double-strand breaks: NBS1 binds to γ-H2AX through FHA/BRCT domain
-
Kobayashi, J. 2004. Molecular mechanism of the recruitment of NBS1/hMRE11/hRAD50 complex to DNA double-strand breaks: NBS1 binds to γ-H2AX through FHA/BRCT domain. J. Radiat. Res. 45:473-478.
-
(2004)
J. Radiat. Res
, vol.45
, pp. 473-478
-
-
Kobayashi, J.1
-
31
-
-
18644367144
-
NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain
-
Kobayashi, J., H. Tauchi, S. Sakamoto, A. Nakamura, K. Morishima, S. Matsuura, T. Kobayashi, K. Tamai, K. Tanimoto, and K. Komatsu. 2002. NBS1 localizes to gamma-H2AX foci through interaction with the FHA/BRCT domain. Curr. Biol. 12:1846-1851.
-
(2002)
Curr. Biol
, vol.12
, pp. 1846-1851
-
-
Kobayashi, J.1
Tauchi, H.2
Sakamoto, S.3
Nakamura, A.4
Morishima, K.5
Matsuura, S.6
Kobayashi, T.7
Tamai, K.8
Tanimoto, K.9
Komatsu, K.10
-
32
-
-
36949013395
-
ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks
-
Lavin, M. F. 2007. ATM and the Mre11 complex combine to recognize and signal DNA double-strand breaks. Oncogene 26:7749-7758.
-
(2007)
Oncogene
, vol.26
, pp. 7749-7758
-
-
Lavin, M.F.1
-
33
-
-
0242413320
-
Regulation of Mre11/Rad50 by Nbs1: Eifects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes
-
Lee, J. H., R. Ghirlando, V. Bhaskara, M. R. Hoffmeyer, J. Gu, and T. T. Paull. 2003. Regulation of Mre11/Rad50 by Nbs1: eifects on nucleotide-dependent DNA binding and association with ataxia-telangiectasia-like disorder mutant complexes. J. Biol. Chem. 278:45171-45181.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 45171-45181
-
-
Lee, J.H.1
Ghirlando, R.2
Bhaskara, V.3
Hoffmeyer, M.R.4
Gu, J.5
Paull, T.T.6
-
34
-
-
36949026694
-
Activation and regulation of ATM kinase activity in response to DNA double-strand breaks
-
Lee, J. H., and T. T. Pauli. 2007. Activation and regulation of ATM kinase activity in response to DNA double-strand breaks. Oncogene 26:7741-7748.
-
(2007)
Oncogene
, vol.26
, pp. 7741-7748
-
-
Lee, J.H.1
Pauli, T.T.2
-
35
-
-
17644409069
-
ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex
-
Lee, J. H., and T. T. Paull. 2005. ATM activation by DNA double-strand breaks through the Mre11-Rad50-Nbs1 complex. Science 308:551-554.
-
(2005)
Science
, vol.308
, pp. 551-554
-
-
Lee, J.H.1
Paull, T.T.2
-
36
-
-
1842431822
-
Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex
-
Lee, J. H., and T. T. Paull. 2004. Direct activation of the ATM protein kinase by the Mre11/Rad50/Nbs1 complex. Science 304:93-96.
-
(2004)
Science
, vol.304
, pp. 93-96
-
-
Lee, J.H.1
Paull, T.T.2
-
37
-
-
0034611728
-
ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway
-
Lim, D. S., S. T. Kim, B. Xu, R. S. Maser, J. Lin, J. H. Petrini, and M. B. Kastan. 2000. ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway. Nature 404:613-617.
-
(2000)
Nature
, vol.404
, pp. 613-617
-
-
Lim, D.S.1
Kim, S.T.2
Xu, B.3
Maser, R.S.4
Lin, J.5
Petrini, J.H.6
Kastan, M.B.7
-
38
-
-
34948872046
-
Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination
-
Limbo, O., C. Chahwan, Y. Yamada, R. A. de Bruin, C. Wittenberg, and P. Russell. 2007. Ctp1 is a cell-cycle-regulated protein that functions with Mre11 complex to control double-strand break repair by homologous recombination. Mol. Cell 28:134-146.
-
(2007)
Mol. Cell
, vol.28
, pp. 134-146
-
-
Limbo, O.1
Chahwan, C.2
Yamada, Y.3
de Bruin, R.A.4
Wittenberg, C.5
Russell, P.6
-
39
-
-
3342915628
-
Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention
-
Lukas, C., F. Melander, M. Stucki, J. Falck, S. Bekker-Jensen, M. Goldberg, Y. Lerenthal, S. P. Jackson, J. Bartek, and J. Lukas. 2004. Mdc1 couples DNA double-strand break recognition by Nbs1 with its H2AX-dependent chromatin retention. EMBO J. 23:2674-2683.
-
(2004)
EMBO J
, vol.23
, pp. 2674-2683
-
-
Lukas, C.1
Melander, F.2
Stucki, M.3
Falck, J.4
Bekker-Jensen, S.5
Goldberg, M.6
Lerenthal, Y.7
Jackson, S.P.8
Bartek, J.9
Lukas, J.10
-
40
-
-
41649088194
-
Nbs1-dependent binding of Mre11 to adenovirus E4 mutant viral DNA is important for inhibiting DNA replication
-
Mathew, S. S., and E. Bridge. 2008. Nbs1-dependent binding of Mre11 to adenovirus E4 mutant viral DNA is important for inhibiting DNA replication. Virology 374:11-22.
-
(2008)
Virology
, vol.374
, pp. 11-22
-
-
Mathew, S.S.1
Bridge, E.2
-
41
-
-
34547686371
-
The cellular Mre11 protein interferes with adenovirus E4 mutant DNA replication
-
Mathew, S. S., and E. Bridge. 2007. The cellular Mre11 protein interferes with adenovirus E4 mutant DNA replication. Virology 365:346-355.
-
(2007)
Virology
, vol.365
, pp. 346-355
-
-
Mathew, S.S.1
Bridge, E.2
-
42
-
-
34249947699
-
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
-
Matsuoka, S., B. A. Ballif, A. Smogorzewska, E. R. McDonald III, K. E. Hurov, J. Luo, C. E. Bakalarski, Z. Zhao, N. Solimini, Y. Lerenthal, Y. Shiloh, S. P. Gygi, and S. J. Elledge. 2007. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 316:1160-1166.
-
(2007)
Science
, vol.316
, pp. 1160-1166
-
-
Matsuoka, S.1
Ballif, B.A.2
Smogorzewska, A.3
McDonald III, E.R.4
Hurov, K.E.5
Luo, J.6
Bakalarski, C.E.7
Zhao, Z.8
Solimini, N.9
Lerenthal, Y.10
Shiloh, Y.11
Gygi, S.P.12
Elledge, S.J.13
-
43
-
-
7744243520
-
The DNA damage response: Sensing and signaling
-
McGowan, C. H., and P. Russell. 2004. The DNA damage response: sensing and signaling. Curr. Opin. Cell Biol. 16:629-633.
-
(2004)
Curr. Opin. Cell Biol
, vol.16
, pp. 629-633
-
-
McGowan, C.H.1
Russell, P.2
-
44
-
-
42449144285
-
Adenovirus E3/19K promotes evasion of NK cell recognition by intracellular sequestration of the NKG2D ligands major histocompatibility complex class I chain-related proteins A and B
-
McSharry, B. P., H. G. Burgert, D. P. Owen, R. J. Stanton, V. Prod'homme, M. Sester, K. Koebernick, V. Groh, T. Spies, S. Cox, A. M. Little, E. C. Wang, P. Tomasec, and G. W. Wilkinson. 2008. Adenovirus E3/19K promotes evasion of NK cell recognition by intracellular sequestration of the NKG2D ligands major histocompatibility complex class I chain-related proteins A and B. J. Virol. 82:4585-4594.
-
(2008)
J. Virol
, vol.82
, pp. 4585-4594
-
-
McSharry, B.P.1
Burgert, H.G.2
Owen, D.P.3
Stanton, R.J.4
Prod'homme, V.5
Sester, M.6
Koebernick, K.7
Groh, V.8
Spies, T.9
Cox, S.10
Little, A.M.11
Wang, E.C.12
Tomasec, P.13
Wilkinson, G.W.14
-
45
-
-
0032931844
-
The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance
-
Moreau, S., J. R. Ferguson, and L. S. Symington. 1999. The nuclease activity of Mre11 is required for meiosis but not for mating type switching, end joining, or telomere maintenance. Mol. Cell. Biol. 19:556-566.
-
(1999)
Mol. Cell. Biol
, vol.19
, pp. 556-566
-
-
Moreau, S.1
Ferguson, J.R.2
Symington, L.S.3
-
46
-
-
0035979213
-
ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation
-
Nghiem, P., P. K. Park, Y. Kim, C. Vaziri, and S. L. Schreiber. 2001. ATR inhibition selectively sensitizes G1 checkpoint-deficient cells to lethal premature chromatin condensation. Proc. Natl. Acad. Sci. USA 98:9092-9097.
-
(2001)
Proc. Natl. Acad. Sci. USA
, vol.98
, pp. 9092-9097
-
-
Nghiem, P.1
Park, P.K.2
Kim, Y.3
Vaziri, C.4
Schreiber, S.L.5
-
47
-
-
0033563229
-
Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex
-
Paull, T. T., and M. Gellert. 1999. Nbs1 potentiates ATP-driven DNA unwinding and endonuclease cleavage by the Mre11/Rad50 complex. Genes Dev. 13:1276-1288.
-
(1999)
Genes Dev
, vol.13
, pp. 1276-1288
-
-
Paull, T.T.1
Gellert, M.2
-
48
-
-
0142011461
-
The cellular response to DNA double-strand breaks: Defining the sensors and mediators
-
Petrini, J. H., and T. H. Stracker. 2003. The cellular response to DNA double-strand breaks: defining the sensors and mediators. Trends Cell Biol. 13:458-462.
-
(2003)
Trends Cell Biol
, vol.13
, pp. 458-462
-
-
Petrini, J.H.1
Stracker, T.H.2
-
49
-
-
0018748442
-
Replicating adenovirus 2 DNA molecules contain terminal protein
-
Robinson, A. J., J. W. Bednar, D. H. Coombs, and G. D. Pearson. 1979. Replicating adenovirus 2 DNA molecules contain terminal protein. Virology 96:143-158.
-
(1979)
Virology
, vol.96
, pp. 143-158
-
-
Robinson, A.J.1
Bednar, J.W.2
Coombs, D.H.3
Pearson, G.D.4
-
50
-
-
0033199892
-
Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine
-
Sarkaria, J. N., E. C. Busby, R. S. Tibbetts, P. Roos, Y. Taya, L. M. Karnitz, and R. T. Abraham. 1999. Inhibition of ATM and ATR kinase activities by the radiosensitizing agent, caffeine. Cancer Res. 59:4375-4382.
-
(1999)
Cancer Res
, vol.59
, pp. 4375-4382
-
-
Sarkaria, J.N.1
Busby, E.C.2
Tibbetts, R.S.3
Roos, P.4
Taya, Y.5
Karnitz, L.M.6
Abraham, R.T.7
-
51
-
-
36549060102
-
Human CtIP promotes DNA end resection
-
Sartori, A. A., C. Lukas, J. Coates, M. Mistrik, S. Fu, J. Bartek, R. Baer, J. Lukas, and S. P. Jackson. 2007. Human CtIP promotes DNA end resection. Nature 450:509-514.
-
(2007)
Nature
, vol.450
, pp. 509-514
-
-
Sartori, A.A.1
Lukas, C.2
Coates, J.3
Mistrik, M.4
Fu, S.5
Bartek, J.6
Baer, R.7
Lukas, J.8
Jackson, S.P.9
-
52
-
-
4444369683
-
Diverse roles for E4orf3 at late times of infection revealed in an E1B 55-kilodalton protein mutant background
-
Shepard, R. N., and D. A. Ornelles. 2004. Diverse roles for E4orf3 at late times of infection revealed in an E1B 55-kilodalton protein mutant background. J. Virol. 78:9924-9935.
-
(2004)
J. Virol
, vol.78
, pp. 9924-9935
-
-
Shepard, R.N.1
Ornelles, D.A.2
-
53
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh, Y. 2003. ATM and related protein kinases: safeguarding genome integrity. Nat. Rev. Cancer 3:155-168.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
54
-
-
13244287780
-
Nbs1 is required for ATR-dependent phosphorylation events
-
Stiff, T., C. Reis, G. K. Alderton, L. Woodbine, M. O'Driscoll, and P. A. Jeggo. 2005. Nbs1 is required for ATR-dependent phosphorylation events. EMBO J. 24:199-208.
-
(2005)
EMBO J
, vol.24
, pp. 199-208
-
-
Stiff, T.1
Reis, C.2
Alderton, G.K.3
Woodbine, L.4
O'Driscoll, M.5
Jeggo, P.A.6
-
55
-
-
0037130170
-
Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex
-
Stracker, T. H., C. T. Carson, and M. D. Weitzman. 2002. Adenovirus oncoproteins inactivate the Mre11-Rad50-NBS1 DNA repair complex. Nature 418:348-352.
-
(2002)
Nature
, vol.418
, pp. 348-352
-
-
Stracker, T.H.1
Carson, C.T.2
Weitzman, M.D.3
-
56
-
-
18744362169
-
Serotype-specific reorganization of the Mre11 complex by adenoviral E4orf3 proteins
-
Stracker, T. H., D. V. Lee, C. T. Carson, F. D. Araujo, D. A. Ornelles, and M. D. Weitzman. 2005. Serotype-specific reorganization of the Mre11 complex by adenoviral E4orf3 proteins. J. Virol. 79:6664-6673.
-
(2005)
J. Virol
, vol.79
, pp. 6664-6673
-
-
Stracker, T.H.1
Lee, D.V.2
Carson, C.T.3
Araujo, F.D.4
Ornelles, D.A.5
Weitzman, M.D.6
-
57
-
-
34248579748
-
The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex
-
Stracker, T. H., M. Morales, S. S. Couto, H. Hussein, and J. H. Petrini. 2007. The carboxy terminus of NBS1 is required for induction of apoptosis by the MRE11 complex. Nature 447:218-221.
-
(2007)
Nature
, vol.447
, pp. 218-221
-
-
Stracker, T.H.1
Morales, M.2
Couto, S.S.3
Hussein, H.4
Petrini, J.H.5
-
58
-
-
3242891189
-
The Mre11 complex and the metabolism of chromosome breaks: The importance of communicating and holding things together
-
Stracker, T. H., J. W. Theunissen, M. Morales, and J. H. Petrini. 2004. The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together. DNA Repair 3:845-854.
-
(2004)
DNA Repair
, vol.3
, pp. 845-854
-
-
Stracker, T.H.1
Theunissen, J.W.2
Morales, M.3
Petrini, J.H.4
-
59
-
-
33646106590
-
gammaH2AX and MDC1: Anchoring the DNA-damage-response machinery to broken chromosomes
-
Stucki, M., and S. P. Jackson. 2006. gammaH2AX and MDC1: anchoring the DNA-damage-response machinery to broken chromosomes. DNA Repair 5:534-543.
-
(2006)
DNA Repair
, vol.5
, pp. 534-543
-
-
Stucki, M.1
Jackson, S.P.2
-
60
-
-
0035980625
-
Molecular regulation and biological function of adenovirus early genes: The E4 ORFs
-
Tauber, B., and T. Dobner. 2001. Molecular regulation and biological function of adenovirus early genes: the E4 ORFs. Gene 278:1-23.
-
(2001)
Gene
, vol.278
, pp. 1-23
-
-
Tauber, B.1
Dobner, T.2
-
61
-
-
0034964498
-
A DNA damage response pathway controlled by Tel1 and the Mre11 complex
-
Usui, T., H. Ogawa, and J. H. Petrini. 2001. A DNA damage response pathway controlled by Tel1 and the Mre11 complex. Mol. Cell 7:1255-1266.
-
(2001)
Mol. Cell
, vol.7
, pp. 1255-1266
-
-
Usui, T.1
Ogawa, H.2
Petrini, J.H.3
-
62
-
-
0142136826
-
Requirement of the MRN complex for ATM activation by DNA damage
-
Uziel, T., Y. Lerenthal, L. Moyal, Y. Andegeko, L. Mittelman, and Y. Shiloh. 2003. Requirement of the MRN complex for ATM activation by DNA damage. EMBO J. 22:5612-5621.
-
(2003)
EMBO J
, vol.22
, pp. 5612-5621
-
-
Uziel, T.1
Lerenthal, Y.2
Moyal, L.3
Andegeko, Y.4
Mittelman, L.5
Shiloh, Y.6
-
63
-
-
19444379003
-
-
Vo, A. T., F. Zhu, X. Wu, F. Yuan, Y. Gao, L. Gu, G. M. Li, T. H. Lee, and C. Her. 2005. hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair. EMBO Rep. 6:438-444.
-
Vo, A. T., F. Zhu, X. Wu, F. Yuan, Y. Gao, L. Gu, G. M. Li, T. H. Lee, and C. Her. 2005. hMRE11 deficiency leads to microsatellite instability and defective DNA mismatch repair. EMBO Rep. 6:438-444.
-
-
-
-
64
-
-
26644453335
-
Simple and highly efficient BAC recombineering using galK selection
-
Warming, S., N. Costantino, D. L. Court, N. A. Jenkins, and N. G. Copeland. 2005. Simple and highly efficient BAC recombineering using galK selection. Nucleic Acids Res. 33:e36.
-
(2005)
Nucleic Acids Res
, vol.33
-
-
Warming, S.1
Costantino, N.2
Court, D.L.3
Jenkins, N.A.4
Copeland, N.G.5
-
65
-
-
0028057972
-
Deletion of the E4 region of the genome produces adenovirus DNA concatemers
-
Weiden, M. D., and H. S. Ginsberg. 1994. Deletion of the E4 region of the genome produces adenovirus DNA concatemers. Proc. Natl. Acad. Sci. USA 91:153-157.
-
(1994)
Proc. Natl. Acad. Sci. USA
, vol.91
, pp. 153-157
-
-
Weiden, M.D.1
Ginsberg, H.S.2
-
66
-
-
0020822949
-
A cell line that supports the growth of a defective early region 4 deletion mutant of human adenovirus type 2
-
Weinberg, D. H., and G. Ketner. 1983. A cell line that supports the growth of a defective early region 4 deletion mutant of human adenovirus type 2. Proc. Natl. Acad. Sci. USA 80:5383-5386.
-
(1983)
Proc. Natl. Acad. Sci. USA
, vol.80
, pp. 5383-5386
-
-
Weinberg, D.H.1
Ketner, G.2
-
67
-
-
33646494210
-
Functions of the adenovirus E4 proteins and their impact on viral vectors
-
Weitzman, M. D. 2005. Functions of the adenovirus E4 proteins and their impact on viral vectors. Front. Biosci. 10:1106-1117.
-
(2005)
Front. Biosci
, vol.10
, pp. 1106-1117
-
-
Weitzman, M.D.1
-
68
-
-
27944462290
-
Inactivating intracellular antiviral responses during adenovirus infection
-
Weitzman, M. D., and D. A. Ornelles. 2005. Inactivating intracellular antiviral responses during adenovirus infection. Oncogene 24:7686-7696.
-
(2005)
Oncogene
, vol.24
, pp. 7686-7696
-
-
Weitzman, M.D.1
Ornelles, D.A.2
-
69
-
-
34948899943
-
Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template
-
Williams, R. S., J. S. Williams, and J. A. Tainer. 2007. Mre11-Rad50-Nbs1 is a keystone complex connecting DNA repair machinery, double-strand break signaling, and the chromatin template. Biochem. Cell Biol. 85:509-520.
-
(2007)
Biochem. Cell Biol
, vol.85
, pp. 509-520
-
-
Williams, R.S.1
Williams, J.S.2
Tainer, J.A.3
-
70
-
-
33846118836
-
Adenovirus ubiquitin-protein ligase stimulates viral late mRNA nuclear export
-
Woo, J. L., and A. J. Berk. 2007. Adenovirus ubiquitin-protein ligase stimulates viral late mRNA nuclear export. J. Virol. 81:575-587.
-
(2007)
J. Virol
, vol.81
, pp. 575-587
-
-
Woo, J.L.1
Berk, A.J.2
-
71
-
-
0034713466
-
ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response
-
Wu, X., V. Ranganathan, D. S. Weisman, W. F. Heine, D. N. Ciccone, T. B. O'Neill, K. E. Crick, K. A. Pierce, W. S. Lane, G. Rathbun, D. M. Livingston, and D. T. Weaver. 2000. ATM phosphorylation of Nijmegen breakage syndrome protein is required in a DNA damage response. Nature 405:477-482.
-
(2000)
Nature
, vol.405
, pp. 477-482
-
-
Wu, X.1
Ranganathan, V.2
Weisman, D.S.3
Heine, W.F.4
Ciccone, D.N.5
O'Neill, T.B.6
Crick, K.E.7
Pierce, K.A.8
Lane, W.S.9
Rathbun, G.10
Livingston, D.M.11
Weaver, D.T.12
-
72
-
-
20744436198
-
ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1
-
You, Z., C. Chahwan, J. Bailis, T. Hunter, and P. Russell. 2005. ATM activation and its recruitment to damaged DNA require binding to the C terminus of Nbs1. Mol. Cell. Biol. 25:5363-5379.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 5363-5379
-
-
You, Z.1
Chahwan, C.2
Bailis, J.3
Hunter, T.4
Russell, P.5
-
73
-
-
0037112610
-
Functional analysis of FHA and BRCT domains of NBS1 in chromatin association and DNA damage responses
-
Zhao, S., W. Renthal, and E. Y. Lee. 2002. Functional analysis of FHA and BRCT domains of NBS1 in chromatin association and DNA damage responses. Nucleic Acids Res. 30:4815-4822.
-
(2002)
Nucleic Acids Res
, vol.30
, pp. 4815-4822
-
-
Zhao, S.1
Renthal, W.2
Lee, E.Y.3
|