Prostaglandins inhibit cytochrome P450 4A activity and contribute to endotoxin-induced hypotension in rats via nitric oxide production

Archives of Pharmacal Research

Volumn 31, Issue 7, 2008, Pages 856-865

  Tunctan, Bahar ^a   Yaghini, Fariborz A ^b   Estes, Anne ^b   Malik, Kafait U ^b  

^a MERSIN UNIVERSITY   (Turkey)

^b UNIVERSITY OF TENNESSEE COLLEGE OF MEDICINE   (United States)

Author keywords

Blood pressure; CYP 4A; Kidney; Nitric oxide; Prostaglandin

Indexed keywords

ALKANE 1 MONOOXYGENASE; AMITROLE; DRUG DERIVATIVE; ENDOTOXIN; ENZYME INHIBITOR; INDOMETACIN; INDUCIBLE NITRIC OXIDE SYNTHASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NONSTEROID ANTIINFLAMMATORY AGENT; PROSTAGLANDIN; PROSTAGLANDIN E2; S,S' 1,4 PHENYLENE BIS(1,2 ETHANEDIYL)BIS ISOTHIOUREA; S,S'-1,4-PHENYLENE-BIS(1,2-ETHANEDIYL)BIS-ISOTHIOUREA; THIOUREA;

ANIMAL; ARTICLE; BIOSYNTHESIS; BLOOD; BLOOD PRESSURE; CHEMICALLY INDUCED DISORDER; DRUG ANTAGONISM; DRUG EFFECT; HYPOTENSION; KIDNEY; MALE; METABOLISM; PATHOPHYSIOLOGY; RAT; SEPTIC SHOCK; SPRAGUE DAWLEY RAT; SYNTHESIS; WESTERN BLOTTING;

ALKANE 1-MONOOXYGENASE; AMITROLE; ANIMALS; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; BLOOD PRESSURE; BLOTTING, WESTERN; DINOPROSTONE; ENDOTOXINS; ENZYME INHIBITORS; HYPOTENSION; INDOMETHACIN; KIDNEY; MALE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; PROSTAGLANDINS; RATS; RATS, SPRAGUE-DAWLEY; SHOCK, SEPTIC; THIOUREA;

EID: 49749095969     PISSN: 02536269     EISSN: 19763786     Source Type: Journal    
DOI: 10.1007/s12272-001-1238-x     Document Type: Article

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