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Volumn 24, Issue 4, 1996, Pages 401-407

Endotoxemia in rats is associated with induction of the P4504A subfamily and suppression of several other forms of cytochrome P450

Author keywords

[No Author keywords available]

Indexed keywords

BACTERIUM LIPOPOLYSACCHARIDE; CYTOCHROME P450; CYTOCHROME P450 ISOENZYME; LAURIC ACID; MESSENGER RNA; OXYGENASE;

EID: 0029988591     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (93)

References (52)
  • 2
    • 0021194781 scopus 로고
    • Human keritinocytes and monocytes release factors which regulate the synthesis of major acute phase plasma proteins in hepatic cells from man, rat, and mouse
    • H. Baumann, G. P. Jahreis, D. N. Sauder, and A. Koj: Human keritinocytes and monocytes release factors which regulate the synthesis of major acute phase plasma proteins in hepatic cells from man, rat, and mouse. J. Biol. Chem. 259, 7331-7342 (1984).
    • (1984) J. Biol. Chem. , vol.259 , pp. 7331-7342
    • Baumann, H.1    Jahreis, G.P.2    Sauder, D.N.3    Koj, A.4
  • 3
    • 0017087792 scopus 로고
    • Cytochrome P450 heme and the regulation of hepatic heme oxygenase activity
    • D. M. Bissel and L. E. Hammaker: Cytochrome P450 heme and the regulation of hepatic heme oxygenase activity. Arch. Biochem. Biophys 176, 91-102 (1976).
    • (1976) Arch. Biochem. Biophys , vol.176 , pp. 91-102
    • Bissel, D.M.1    Hammaker, L.E.2
  • 5
    • 0022534617 scopus 로고
    • Factors affecting drug biotransformation
    • K. W. Renton: Factors affecting drug biotransformation. Clin. Biochem. 19, 72-75 (1986).
    • (1986) Clin. Biochem. , vol.19 , pp. 72-75
    • Renton, K.W.1
  • 6
    • 0021243387 scopus 로고
    • Study of biochemical behavior of some exported and nonexported hepatic proteins during acute inflammation reaction in the rat
    • J. L. Mahu and G. Feldman: Study of biochemical behavior of some exported and nonexported hepatic proteins during acute inflammation reaction in the rat. Enzyme 31, 234-240 (1984).
    • (1984) Enzyme , vol.31 , pp. 234-240
    • Mahu, J.L.1    Feldman, G.2
  • 7
    • 0028007169 scopus 로고
    • Endotoxin administration to humans inhibits hepatic cytochrome P450-mediated drug metabolism
    • S. I. Shedlofsky, B. C Israel, C. J. McClain, D. B. Hill, and R. A. Blouin: Endotoxin administration to humans inhibits hepatic cytochrome P450-mediated drug metabolism. J. Clin. Invest. 94, 2209-2214 (1994)
    • (1994) J. Clin. Invest. , vol.94 , pp. 2209-2214
    • Shedlofsky, S.I.1    Israel, B.C.2    McClain, C.J.3    Hill, D.B.4    Blouin, R.A.5
  • 8
    • 0024388905 scopus 로고
    • Suppression of constitutive cytochrome P450 gene expression in livers of rats undergoing acute phase response to endotoxin
    • E. T. Morgan: Suppression of constitutive cytochrome P450 gene expression in livers of rats undergoing acute phase response to endotoxin. Mol. Pharmacol. 36, 699-707 (1989).
    • (1989) Mol. Pharmacol. , vol.36 , pp. 699-707
    • Morgan, E.T.1
  • 9
    • 0025116032 scopus 로고
    • Transcriptional and post-transcriptional suppression of P450IIC11 and P450IIC12 by inflammation
    • K. Wright and E. T. Morgan: Transcriptional and post-transcriptional suppression of P450IIC11 and P450IIC12 by inflammation. FEBS Lett. 271, 59-61 (1990).
    • (1990) FEBS Lett. , vol.271 , pp. 59-61
    • Wright, K.1    Morgan, E.T.2
  • 10
    • 0027394075 scopus 로고
    • Down-regulation of multiple cytochrome P450 gene products by inflammatory mediators in vivo
    • E. T. Morgan. Down-regulation of multiple cytochrome P450 gene products by inflammatory mediators in vivo. Biochem. Pharmacol. 45, 415-419 (1993).
    • (1993) Biochem. Pharmacol. , vol.45 , pp. 415-419
    • Morgan, E.T.1
  • 11
    • 0026668922 scopus 로고
    • Effects of interleukin-1α on the activities and gene expression of the cytochrome P450HD subfamily
    • K. Kurokohchi, H. Yoneyama, Y. Matsuo, M. Nishioka, and Y. Ichikawa: Effects of interleukin-1α on the activities and gene expression of the cytochrome P450HD subfamily. Biochem. Pharmacol. 44, 1669-1674 (1992).
    • (1992) Biochem. Pharmacol. , vol.44 , pp. 1669-1674
    • Kurokohchi, K.1    Yoneyama, H.2    Matsuo, Y.3    Nishioka, M.4    Ichikawa, Y.5
  • 13
    • 0028135570 scopus 로고
    • Selective suppression of cytochrome P450 gene expression by interleukins 1 and 6 in rat liver
    • E T. Morgan, K. B. Thomas, R. Swanson, T. Vales, J. Hwang, and K. Wright: Selective suppression of cytochrome P450 gene expression by interleukins 1 and 6 in rat liver. Biochim. Biophys. Acta 1219, 475-483 (1994).
    • (1994) Biochim. Biophys. Acta , vol.1219 , pp. 475-483
    • Morgan, E.T.1    Thomas, K.B.2    Swanson, R.3    Vales, T.4    Hwang, J.5    Wright, K.6
  • 14
    • 0029036153 scopus 로고
    • Suppression of the constitutive expression of cytochrome P4502C11 by cytokines and interferons in primary cultures of rat hepatocytes: Comparison with induction of acute-phase genes and demonstration that CYP2C11 promoter sequences are involved in the suppressive response to interleukins 1 and 6
    • J.-Q. Chen, A. Ström, J.-Å. Gustafsson, and E. T. Morgan: Suppression of the constitutive expression of cytochrome P4502C11 by cytokines and interferons in primary cultures of rat hepatocytes: comparison with induction of acute-phase genes and demonstration that CYP2C11 promoter sequences are involved in the suppressive response to interleukins 1 and 6. Mol. Pharmacol. 47, 940-947 (1995).
    • (1995) Mol. Pharmacol. , vol.47 , pp. 940-947
    • Chen, J.-Q.1    Ström, A.2    Gustafsson, J.-Å.3    Morgan, E.T.4
  • 15
    • 0025049885 scopus 로고
    • Pretranslational suppression of cytochrome P450h(IIC11) gene expression in rat liver after administration of interferon inducers
    • E. T. Morgan and C. A. Norman: Pretranslational suppression of cytochrome P450h(IIC11) gene expression in rat liver after administration of interferon inducers. Drug Metab. Dispos. 18, 649-653 (1989).
    • (1989) Drug Metab. Dispos. , vol.18 , pp. 649-653
    • Morgan, E.T.1    Norman, C.A.2
  • 17
    • 0028013446 scopus 로고
    • Regulation of cytochrome P4501A and cytochrome P4502E induction in the rat during the production of interferon α/β
    • A. E. Cribb, E. Delaporte, S. G. Kim, R. F. Novak, and K. W. Renton: Regulation of cytochrome P4501A and cytochrome P4502E induction in the rat during the production of interferon α/β. J. Pharmacol. Exp. Ther. 268, 487-494 (1994).
    • (1994) J. Pharmacol. Exp. Ther. , vol.268 , pp. 487-494
    • Cribb, A.E.1    Delaporte, E.2    Kim, S.G.3    Novak, R.F.4    Renton, K.W.5
  • 18
    • 0017057951 scopus 로고
    • Properties of electrophoretically homogeneous phenobarbital-inducible froms of liver microsomal cytochrome P450
    • D.A. Haugen and M.J. Coon: Properties of electrophoretically homogeneous phenobarbital-inducible froms of liver microsomal cytochrome P450. J. Biol. Chem. 251, 7929-7939 (1976).
    • (1976) J. Biol. Chem. , vol.251 , pp. 7929-7939
    • Haugen, D.A.1    Coon, M.J.2
  • 19
    • 0023277545 scopus 로고
    • Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
    • P. Chomczynski and N. Sacchi: Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Anal. Biochem. 162, 156-159 (1987).
    • (1987) Anal. Biochem. , vol.162 , pp. 156-159
    • Chomczynski, P.1    Sacchi, N.2
  • 21
    • 0024430873 scopus 로고
    • Northern blot normalization with a 28S rRNA probe
    • V. Barbu and F. Dautry: Northern blot normalization with a 28S rRNA probe. Nucleic Acids Res. 17, 7115 (1989).
    • (1989) Nucleic Acids Res. , vol.17 , pp. 7115
    • Barbu, V.1    Dautry, F.2
  • 22
    • 0024385160 scopus 로고
    • The rat clofibrate-inducible CYP4A subfamily II. cDNA sequence of IVA3. mapping of the Cyp4A locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes
    • S. Kimura, J. P. Hardwick, C. A. Kozak, and F. J. Gonzalez: The rat clofibrate-inducible CYP4A subfamily II. cDNA sequence of IVA3. mapping of the Cyp4A locus to mouse chromosome 4, and coordinate and tissue-specific regulation of the CYP4A genes. DNA 8, 517-525 (1989).
    • (1989) DNA , vol.8 , pp. 517-525
    • Kimura, S.1    Hardwick, J.P.2    Kozak, C.A.3    Gonzalez, F.J.4
  • 23
    • 0026671184 scopus 로고
    • Sex dependent expression and clofibrate inducibility of cytochrome P4504A fatty acid omega hydroxylases
    • S. S. Sundseth and D. J. Waxman: Sex dependent expression and clofibrate inducibility of cytochrome P4504A fatty acid omega hydroxylases. J. Biol. Chem. 267, 3915-3921 (1992).
    • (1992) J. Biol. Chem. , vol.267 , pp. 3915-3921
    • Sundseth, S.S.1    Waxman, D.J.2
  • 25
    • 78651165715 scopus 로고
    • The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein in nature
    • T. Omura and R. Sato: The carbon monoxide-binding pigment of liver microsomes. I. Evidence for its hemoprotein in nature. J. Biol. Chem. 239, 2370-2378 (1964).
    • (1964) J. Biol. Chem. , vol.239 , pp. 2370-2378
    • Omura, T.1    Sato, R.2
  • 26
    • 0026324038 scopus 로고
    • Omega and (omega-1)-hydroxylation of eicosanoids and fatty acids by high-performance liquid chromatography
    • R. T. Okita, J. E. Clark, J. R. Okita, and B. S. S. Masters: Omega and (omega-1)-hydroxylation of eicosanoids and fatty acids by high-performance liquid chromatography. Methods Enzymol. 206, 432-441 (1991)
    • (1991) Methods Enzymol. , vol.206 , pp. 432-441
    • Okita, R.T.1    Clark, J.E.2    Okita, J.R.3    Masters, B.S.S.4
  • 27
    • 0027056410 scopus 로고
    • Identification of rabbit cytochrome P450 2C1 and 2C2 as arachidonic acid epoxygenases
    • R. M. Laethem and D. R. Koop: Identification of rabbit cytochrome P450 2C1 and 2C2 as arachidonic acid epoxygenases. Mol. Pharmacol. 42, 958-963 (1992).
    • (1992) Mol. Pharmacol. , vol.42 , pp. 958-963
    • Laethem, R.M.1    Koop, D.R.2
  • 28
    • 0026739489 scopus 로고
    • Purification and properties of a cytochrome P450 arachidonic acid epoxygenase from rabbit renal cortex
    • R. M. Laethem, C. L. Laethem, and D. R. Koop: Purification and properties of a cytochrome P450 arachidonic acid epoxygenase from rabbit renal cortex. J. Biol. Chem. 267, 5552-5559 (1992).
    • (1992) J. Biol. Chem. , vol.267 , pp. 5552-5559
    • Laethem, R.M.1    Laethem, C.L.2    Koop, D.R.3
  • 29
    • 0026773423 scopus 로고
    • Hormone- And substrate-regulated intracellular degradation of cytochrome P450(2E1) involving MgATP-activated rapid proteolysis in the endoplasmic reticulum membranes
    • E. Eliasson, S. Mkrtchian, and M. Ingelman-Sundberg: Hormone- and substrate-regulated intracellular degradation of cytochrome P450(2E1) involving MgATP-activated rapid proteolysis in the endoplasmic reticulum membranes. J. Biol. Chem. 267, 15765-15769 (1992).
    • (1992) J. Biol. Chem. , vol.267 , pp. 15765-15769
    • Eliasson, E.1    Mkrtchian, S.2    Ingelman-Sundberg, M.3
  • 30
    • 0027654250 scopus 로고
    • Characterization of cytochromes P450 in liver and kidney of rats treated with di-2-ethylhexyl phthalate
    • J. R. Okita, P. J. Castle, and R. T Okita: Characterization of cytochromes P450 in liver and kidney of rats treated with di-(2-ethylhexyl (phthalate. J. Biochem. Toxicol. 8, 135-144 (1993).
    • (1993) J. Biochem. Toxicol. , vol.8 , pp. 135-144
    • Okita, J.R.1    Castle, P.J.2    Okita, R.T.3
  • 31
    • 0026021370 scopus 로고
    • Determination of the cytochrome P450 IV marker omegahydroxylauric acid, by high performance liquid chromatography and fluorimetric detection
    • H. A. A. M. Dirven, A A. G. M. DeBruijn, P. J. M. Sessink, and F. J. Jongeneelen: Determination of the cytochrome P450 IV marker omegahydroxylauric acid, by high performance liquid chromatography and fluorimetric detection. J. Chromatogr. 564, 266-271 (1991).
    • (1991) J. Chromatogr. , vol.564 , pp. 266-271
    • Dirven, H.A.A.M.1    Debruijn, A.A.G.M.2    Sessink, P.J.M.3    Jongeneelen, F.J.4
  • 32
    • 0028151666 scopus 로고
    • Lauric acid as a model substrate for the simultaneous determination of cytochrome P450 2E1 and 4A in hepatic microsomes
    • S E. Clarke, S. J. Baldwin, J. C. Bloomer, A. D. Ayrton, R. S. Sozio, and R. J. Chenery: Lauric acid as a model substrate for the simultaneous determination of cytochrome P450 2E1 and 4A in hepatic microsomes. Chem. Res. Toxicol. 7, 836-842 (1994).
    • (1994) Chem. Res. Toxicol. , vol.7 , pp. 836-842
    • Clarke, S.E.1    Baldwin, S.J.2    Bloomer, J.C.3    Ayrton, A.D.4    Sozio, R.S.5    Chenery, R.J.6
  • 33
    • 0025909690 scopus 로고
    • Suppression of P4502C12 gene expression and elevation of actin messenger ribonucleic acid levels in the livers of female rats after injection of the interferon inducer poly rI.poly rC
    • E.T. Morgan: Suppression of P4502C12 gene expression and elevation of actin messenger ribonucleic acid levels in the livers of female rats after injection of the interferon inducer poly rI.poly rC. Biochem. Pharmacol. 42, 51-57 (1991).
    • (1991) Biochem. Pharmacol. , vol.42 , pp. 51-57
    • Morgan, E.T.1
  • 34
    • 0026738076 scopus 로고
    • Suppression of hepatic drug metabolism by the Interferon inducer, polyriboinosinic acid:polyribocitidylic acid
    • H. Sakai, T. Okamoto, and Y. Kikkawa: Suppression of hepatic drug metabolism by the Interferon inducer, polyriboinosinic acid:polyribocitidylic acid. J. Pharmacol. Exp. Ther. 263, 381-386 (1992).
    • (1992) J. Pharmacol. Exp. Ther. , vol.263 , pp. 381-386
    • Sakai, H.1    Okamoto, T.2    Kikkawa, Y.3
  • 35
    • 0026750741 scopus 로고
    • The suppression of hepatic cytochrome P4504A mRNA mediated by the Interferon inducer polyinosinic acid-polycytidylic acid
    • L. C. Knickle, D. Spencer, and K. W. Renton: The suppression of hepatic cytochrome P4504A mRNA mediated by the Interferon inducer polyinosinic acid-polycytidylic acid. Biochem. Pharmacol. 44, 604-608 (1992).
    • (1992) Biochem. Pharmacol. , vol.44 , pp. 604-608
    • Knickle, L.C.1    Spencer, D.2    Renton, K.W.3
  • 36
    • 0026578080 scopus 로고
    • Neutrophil depletion protects against liver injury from bacterial endotoxin
    • J. A. Hewett, A. E. Schueltze, S. VanCise, and R. A. Roth: Neutrophil depletion protects against liver injury from bacterial endotoxin. Lab. Invest. 66, 347-361 (1992).
    • (1992) Lab. Invest. , vol.66 , pp. 347-361
    • Hewett, J.A.1    Schueltze, A.E.2    VanCise, S.3    Roth, R.A.4
  • 37
    • 0027932426 scopus 로고
    • Evidence that cytochrome P4502E1 is involved in the (omega-1)-hydroxylation of lauric acid in rat liver microsomes
    • Y. Amet, F. Berthou, T. Goasduff, J. P. Salaun, L. Le Breton, and J. F. Menez: Evidence that cytochrome P4502E1 is involved in the (omega-1)-hydroxylation of lauric acid in rat liver microsomes. Biochem. Biophys. Res. Commun. 203, 1168-1174 (1994).
    • (1994) Biochem. Biophys. Res. Commun. , vol.203 , pp. 1168-1174
    • Amet, Y.1    Berthou, F.2    Goasduff, T.3    Salaun, J.P.4    Le Breton, L.5    Menez, J.F.6
  • 38
    • 0027179792 scopus 로고
    • Changes in amounts of cytochrome P450 isozymes and levels of catalytic activities in hepatic and renal microsomes of rats with streptozotocin-induced diabetes
    • N. Shimojo, T. Ishizaki, S. Imaoka, Y. Funae, S. Fujii, and K Okuda: Changes in amounts of cytochrome P450 isozymes and levels of catalytic activities in hepatic and renal microsomes of rats with streptozotocin-induced diabetes. Biochem. Pharmacol. 46, 621-627 (1993).
    • (1993) Biochem. Pharmacol. , vol.46 , pp. 621-627
    • Shimojo, N.1    Ishizaki, T.2    Imaoka, S.3    Funae, Y.4    Fujii, S.5    Okuda, K.6
  • 39
    • 0026730908 scopus 로고
    • The peroxisome-proliferator-activated receptor mediates the induction of CYP4A6, a cytochrome P450 fatty acid ω-hydroxylase, by clofibric acid
    • A. S. Muerhoff, K. J. Griffin, and E. F. Johnson: The peroxisome-proliferator-activated receptor mediates the induction of CYP4A6, a cytochrome P450 fatty acid ω-hydroxylase, by clofibric acid. J. Biol. Chem. 267, 19051-19053 (1992).
    • (1992) J. Biol. Chem. , vol.267 , pp. 19051-19053
    • Muerhoff, A.S.1    Griffin, K.J.2    Johnson, E.F.3
  • 40
    • 0026541591 scopus 로고
    • The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene
    • J. D. Tugwood, I. Issemann, R. G. Anderson, K. R. Bundell, W. L. McPheat. and S. Green: The mouse peroxisome proliferator activated receptor recognizes a response element in the 5′ flanking sequence of the rat acyl CoA oxidase gene. EMBO J. 11, 433-439 (1992).
    • (1992) EMBO J. , vol.11 , pp. 433-439
    • Tugwood, J.D.1    Issemann, I.2    Anderson, R.G.3    Bundell, K.R.4    McPheat, W.L.5    Green, S.6
  • 41
    • 0026545711 scopus 로고
    • A role for fatty acid binding protein in peroxisome proliferation?
    • I. Issemann, R. Prince, J. Tugwood, and S. Green: A role for fatty acid binding protein in peroxisome proliferation? Biochem. Soc. Trans. 20, 824-827 (1992)
    • (1992) Biochem. Soc. Trans. , vol.20 , pp. 824-827
    • Issemann, I.1    Prince, R.2    Tugwood, J.3    Green, S.4
  • 42
    • 0025604385 scopus 로고
    • On the mechanism of microsomal cytochrome P450IVA1 and peroxisome proliferation in rat liver by clofibrate
    • M. N. Milton, C. R. Elcombe, and G. G. Gibson: On the mechanism of microsomal cytochrome P450IVA1 and peroxisome proliferation in rat liver by clofibrate. Biochem Pharmacol. 40, 2727-2732 (1990).
    • (1990) Biochem Pharmacol. , vol.40 , pp. 2727-2732
    • Milton, M.N.1    Elcombe, C.R.2    Gibson, G.G.3
  • 44
    • 0026584510 scopus 로고
    • A uniform alteration in serum lipid metabolism occurring during inflammation in mice
    • S. Kitagawa, Y. Yamaguchi, N. Imaizumi, M. Kumtomo, and M. Fujiwara: A uniform alteration in serum lipid metabolism occurring during inflammation in mice. Jpn. J. Pharmacol. 58, 37-46 (1992).
    • (1992) Jpn. J. Pharmacol. , vol.58 , pp. 37-46
    • Kitagawa, S.1    Yamaguchi, Y.2    Imaizumi, N.3    Kumtomo, M.4    Fujiwara, M.5
  • 45
    • 0028041153 scopus 로고
    • Impairment of peroxisomal β-oxidation system by endotoxin treatment
    • G. Singh, C. D. Hanevold, and I. Singh: Impairment of peroxisomal β-oxidation system by endotoxin treatment. Mol. Cell. Biochem. 135, 187-193 (1994).
    • (1994) Mol. Cell. Biochem. , vol.135 , pp. 187-193
    • Singh, G.1    Hanevold, C.D.2    Singh, I.3
  • 46
    • 0026509949 scopus 로고
    • NF-kB and related proteins: Rel/dorsal homologies meet ankyrin-like repeats
    • V. Blank, P. Kourilsky, and A. Israel: NF-kB and related proteins: Rel/dorsal homologies meet ankyrin-like repeats. Trends. Biochem. Sci. 17, 135-140, (1992).
    • (1992) Trends. Biochem. Sci. , vol.17 , pp. 135-140
    • Blank, V.1    Kourilsky, P.2    Israel, A.3
  • 47
    • 0026569586 scopus 로고
    • Cytochrome P450 and the arachidonate cascade
    • J. H. Capdevila, J. R. Falck, and R. W. Estabrook: Cytochrome P450 and the arachidonate cascade. FASEB J. 6, 731-736. (1992).
    • (1992) FASEB J. , vol.6 , pp. 731-736
    • Capdevila, J.H.1    Falck, J.R.2    Estabrook, R.W.3
  • 48
    • 0028904786 scopus 로고
    • Role of cytochrome P450 enzymes and metabolites of arachidonic acid in the control of vascular tone
    • D. R. Harder, W. B Campbell, and R. J. Roman: Role of cytochrome P450 enzymes and metabolites of arachidonic acid in the control of vascular tone. J. Vasc. Res. 32, 79-92 (1995).
    • (1995) J. Vasc. Res. , vol.32 , pp. 79-92
    • Harder, D.R.1    Campbell, W.B.2    Roman, R.J.3
  • 49
    • 0027751698 scopus 로고
    • Hepatic and extrahepatic pathobiology of bacterial lipopolysaccharides
    • J. A. Hewett and R. A. Roth: Hepatic and extrahepatic pathobiology of bacterial lipopolysaccharides. Pharmacol. Rev. 45, 381-411 (1993).
    • (1993) Pharmacol. Rev. , vol.45 , pp. 381-411
    • Hewett, J.A.1    Roth, R.A.2
  • 50
    • 0024521525 scopus 로고
    • Induction of rat hepatic N-nitrosodimethylamine demethylase by acetone is due to protein stabilization
    • B.-J. Song, R. L. Veech, S. S. Park, H. V. Gelboin, and F. J. Gonzalez: Induction of rat hepatic N-nitrosodimethylamine demethylase by acetone is due to protein stabilization. J. Biol. Chem. 264, 3568-3572 (1989).
    • (1989) J. Biol. Chem. , vol.264 , pp. 3568-3572
    • Song, B.-J.1    Veech, R.L.2    Park, S.S.3    Gelboin, H.V.4    Gonzalez, F.J.5
  • 51
    • 0028641564 scopus 로고
    • Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: Evidence that CYP2E1 possesses a rapid phase half-life of 6 hours or less
    • B. J. Roberts, S. E. Shoaf, K. S. Jeong, and B. J. Song: Induction of CYP2E1 in liver, kidney, brain and intestine during chronic ethanol administration and withdrawal: evidence that CYP2E1 possesses a rapid phase half-life of 6 hours or less. Biochem. Biophys. Res. Commun. 205, 1064-1071 (1994).
    • (1994) Biochem. Biophys. Res. Commun. , vol.205 , pp. 1064-1071
    • Roberts, B.J.1    Shoaf, S.E.2    Jeong, K.S.3    Song, B.J.4


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