Selective inhibition of cyclooxygenase-2 by NS-398 in endotoxin shock rats in vivo

Inflammation Research

Volumn 46, Issue 12, 1997, Pages 496-502

  Futaki, N ^a   Takahashi, S ^a   Kitagawa, T ^a   Yamakawa, Y ^a   Tanaka, M ^a   Higuchi, S ^a  

^a TAISHO PHARMACEUTICAL CO LTD   (Japan)

Author keywords

Cyclooxygenase 1; Cyclooxygenase 2; NS 398; NSAIDS; Selective inhibition

Indexed keywords

ARACHIDONIC ACID; CYCLOOXYGENASE 1; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITOR; ENDOTOXIN; INDOMETACIN; LIPOPOLYSACCHARIDE; MESSENGER RNA; N (2 CYCLOHEXYLOXY 4 NITROPHENYL)METHANESULFONAMIDE; PROSTAGLANDIN E2; PROSTAGLANDIN F1 ALPHA; THROMBOXANE B2;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; AORTA; ARTICLE; CONTROLLED STUDY; DRUG POTENCY; DRUG SELECTIVITY; ENZYME INHIBITION; LEUKOCYTE; MALE; NONHUMAN; ORAL DRUG ADMINISTRATION; PROSTAGLANDIN BLOOD LEVEL; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SEPTIC SHOCK;

ANIMALS; CYCLOOXYGENASE 2; CYCLOOXYGENASE 2 INHIBITORS; CYCLOOXYGENASE INHIBITORS; ISOENZYMES; LIPOPOLYSACCHARIDES; MALE; NITROBENZENES; POLYMERASE CHAIN REACTION; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; PROSTAGLANDINS; RATS; RATS, WISTAR; SHOCK, SEPTIC; SULFONAMIDES;

EID: 0031465847     PISSN: 10233830     EISSN: None     Source Type: Journal    
DOI: 10.1007/s000110050232     Document Type: Article

References (22)

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