Homeostatic imbalance between apoptosis and cell renewal in the liver of premature aging XpdTTD mice

PLoS ONE

Volumn 3, Issue 6, 2008, Pages

  Park, Jung Yoon ^a   Cho, Mi Ook ^a   Leonard, Shanique ^b   Calder, Brent ^c   Mian, I Saira ^d   Kim, Woo Ho ^e   Wijnhoven, Susan ^f   van Steeg, Harry ^f   Mitchell, James ^g   van der Horst, Gijsbertus T J ^g   Hoeijmakers, Jan ^g   Cohen, Pinchas ^h   Vijg, Jan ^c   Suh, Yousin ^a  

^a ALBERT EINSTEIN COLLEGE OF MEDICINE   (United States)

^b UNIVERSITY OF TEXAS HEALTH SCIENCE CENTER AT SAN ANTONIO   (United States)

^c BUCK INSTITUTE FOR RESEARCH ON AGING   (United States)

^d LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

^e Seoul National University College of Medicine   (South Korea)

^f NATIONAL INSTITUTE FOR PUBLIC HEALTH AND THE ENVIRONMENT   (Netherlands)

^g ERASMUS MEDICAL CENTER   (Netherlands)

^h UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

DNA; SOMATOMEDIN C; XERODERMA PIGMENTOSUM GROUP D PROTEIN; ERCC2 PROTEIN, MOUSE;

AGE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; CANCER INCIDENCE; CELL PROLIFERATION; CELL RENEWAL; CONTROLLED STUDY; DNA DAMAGE; DNA REPAIR; ENERGY METABOLISM; FEMALE; GENE EXPRESSION; GENE MUTATION; GENETIC TRANSCRIPTION; GENOTOXICITY; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; LIFESPAN; LIVER METABOLISM; MICROARRAY ANALYSIS; MOUSE; MUTANT; NONHUMAN; PHENOTYPE; PREMATURE AGING; SIGNAL TRANSDUCTION; TRICHOTHIODYSTROPHY; WILD TYPE; ANIMAL; GENETICS; LIVER; METABOLISM; PATHOLOGY;

MUS;

AGING, PREMATURE; ANIMALS; APOPTOSIS; DNA DAMAGE; ENERGY METABOLISM; FEMALE; HOMEOSTASIS; IMMUNOHISTOCHEMISTRY; INSULIN-LIKE GROWTH FACTOR I; LIVER; MICE; TRANSCRIPTION, GENETIC; XERODERMA PIGMENTOSUM GROUP D PROTEIN;

EID: 48649106278     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0002346     Document Type: Article

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