Hepatic gene and protein expression of primary components of the IGF-I axis in long lived Snell dwarf mice

Mechanisms of Ageing and Development

Volumn 126, Issue 6-7, 2005, Pages 692-704

  Papaconstantinou, John ^a   DeFord, James H ^a   Gerstner, Arpad ^a   Hsieh, C C ^a   Boylston, William H ^a   Guigneaux, Michelle M ^b   Flurkey, Kevin ^c   Harrison, David E ^c  

^a University of Texas Medical Branch School of Medicine   (United States)

^b UNIVERSITY OF TEXAS MEDICAL BRANCH   (United States)

^c JACKSON LABORATORY   (United States)

Author keywords

IGF I axis; Liver; Longevity; mRNA levels; Protein levels; Snell dwarf

Indexed keywords

GENE PRODUCT; MESSENGER RNA; SOMATOMEDIN; SOMATOMEDIN BINDING PROTEIN;

AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; FEMALE; GENE EXPRESSION; GENE EXPRESSION REGULATION; LIVER; LONGEVITY; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; ORGANOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; RNA TRANSCRIPTION; TRANSLATION REGULATION;

ANIMALS; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION; GROWTH HORMONE; INSULIN-LIKE GROWTH FACTOR I; LIVER; LONGEVITY; MICE; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; SIGNAL TRANSDUCTION;

MAMMALIA;

EID: 18844386767     PISSN: 00476374     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.mad.2005.01.002     Document Type: Article

References (60)

1. Affymetrix, 2002a. Affymetrix Microarray Suite Users Guide Version 5.0.
2. Affymetrix, 2002b. GeneChip Expression Analysis: Data Analysis Fundamentals.
3. A. Bartke, H.M. Brown-Borg, A.M. Bode, J. Carlson, W.S. Hunter, and R.T. Bronson Does growth hormone prevent or accelerate aging? Exp. Gerontal. 33 1998 675 687
4. A. Bartke, V. Chandrashekar, F. Dominici, D. Turyn, B. Kinney, R. Steger, and J.J. Kopchick Insulin-like growth factor 1 (IGF-I) and aging: controversies and new insights Biogerontology 4 2003 1 8
5. W.H. Boylston, A. Gerstner, J.H. DeFord, M.A. Madsen, K. Flurkey, D.E. Harrison, and J. Papaconstantinou Altered Cholesterologenic and lipogenic transcriptional profile in livers of aging Snell dwarf (Pit1 dw/dwj) Mice Aging Cell 3 5 2004 283 296
6. H.M. Brown-Borg, K.E. Borg, C.J. Meliska, and A. Bartke Dwarf mice and the aging process Nature 384 1996 33
7. E. Chin, J. Zhou, J. Dai, R.C. Baxter, and C.A. Bondy Cellular localization and regulation of gene expression for components of the insulin-like growth factor tertiary binding protein complex Endocrinology 134 1994 2498 2504
8. D.J. Clancy, D. Gems, L.G. Harshman, S. Oldham, H. Stocker, E. Hafen, S.J. Leevers, and L Partridge Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein Science 292 2001 104 106
9. K.T. Coshigano, A.N. Holland, M.E. Riders, E.O. List, A. Flyrbjerg, and J.H. Kopchick Decreased body weights, insulin, and insulin-like growth factor I levels and increased life-span Endocrinology 144 2003 3799 3810
10. J. Dai, and R.C. Baxter Regulation in vivo of the acid-labile subunit of the rat serum insulin-like growth factor-binding protein complex Endocrinology 135 1994 2335 2341
11. J.B. Dorman, B. Albinder, T. Shroyer, and C. Kenyon The age-1 and daf-2 genes function as a common pathway to control the lifespan of Caenorhabditis elegans Genetics 141 1995 1399 1406
12. I. Dozmorov, A. Galecki, Y. Chang, R. Krzesicki, M. Vergara, and R.A. Miller Gene expression profile of long-lived Snell dwarf mice J. Gerontol. A: Biol. Sci. Med. Sci. 57 2002 B99 B108
13. K. Flurkey, J. Papaconstantinou, R.A. Miller, and D.E. Harrison Lifespan extension and delayed immune and collagen aging in mutant mice with defects in growth hormone production Proc. Nat'l. Acad. Sci. U.S.A. 98 2001 6736 6741
14. dw can increase lifespan in mice Mech. Ageing Dev. 123 2002 121 130
15. R.A. Frost, and L. Tseng Insulin-like growth factor-binding protein-1 is phosphorylated by cultured human endometrial stromal cells and multiple protein kinases in vitro J. Biol. Chem. 266 1991 18982 18988
16. Y.W. Fung, R. Wang, and C.C. Liew Characterization of a human cardiac gene which encodes for a I domain protein and is developmentally expressed in myocardial development J. Mol. Cell. Cardiol. 28 1996 1203 1210
17. D. Gems, S. Pletcher, and L. Partridge Interpreting interactions between treatments that slow aging Aging Cell 1 2002 1 19
18. L. Guarante, and C. Kenyon Genetic pathways that regulate ageing in model organizations Nature 408 2000 255 262
19. V.K. Han, D.G. Matsell, P.J. Delhanty, D.J. Hill, S. Shimasaki, and K. Nygard IGF-binding protein mRNAs in human fetus: tissue and cellular distribution of developmental expression Horm. Res. 45 1996 160 166
20. R.O. Haynes Integrins: versatility, modulation and signaling in cell adhesion Cell 69 1992 11 25
21. M. Holzenberger, J. Dupont, B. Ducos, P. Leneuve, A. Geloen, P.C. Even, P. Cervera, and Y. Le Douc IGF-I receptor regulates lifespan and resistance to oxidative stress in mice Nature 421 2003 182 187
22. C.-C. Hsieh, J.H. DeFord, K. Flurkey, D.E. Harrison, and J. Papaconstantinou Implications of the insulin signaling pathway in Snell dwarf mouse longevity: a similarity with C. elegans longevity paradigm Mech. Ageing Dev. 123 2002 1229 1244
23. C.-C. Hsieh, J.H. DeFord, K. Flurkey, D.E. Harrison, and J. Papaconstantinou Effects of the Pit1 Mutation on the insulin signaling pathway: implications on the longevity of the long-lived Snell dwarf mouse Mech. Ageing Dev. 123 2002 1245 1255
24. J.I. Jones, and D.R. Clemmons Insulin-like growth factors and their binding proteins: biological actions Endocr. Rev. 16 1995 3 34
25. J.I. Jones, A. Gockerman, W.H. Busby Jr., G. Wright, and D.R. Clemmons Insulin-like growth factor binding protein 1 stimulates cell migration and binds to the alpha 5 beta 1 integrin by means of its Arg-Gly-Asp sequence Proc. Natl. Acad. Sci. U.S.A. 90 1993 10553 10557
26. R.W. Jyung, J.A. Mustoe, W.H. Busby, and D.R. Clemmons Increased wound-breaking strength induced by insulin-like growth factor I in combination with insulin-like growth factor binding protein-1 Surgery 115 1994 233 239
27. C. Kenyon, J. Chang, E. Gensch, A. Rudner, and R.A. Tabtiang A C. elegans mutant that lives as long as wild type Nature 366 1993 461 464
28. K.D. Kimura, H.G. Tissenbaum, Y. Liu, and G. Ruvkun daf-2, an insulin receptor-like gene that regulates longevity and diapause in Caenorhabditis elegans Science 277 1997 942 946
29. B.A. Kinney-Forshee, N.E. Kinney, R.W. Steger, and A. Bartke Could a deficiency in growth hormone signaling be beneficial to the aging brain? Physiol. Behav. 80 2004 589 594
30. B.A. Kinney, C.J. Meliska, R.W. Steger, and A. Bartke Evidence that Ames dwarf mice age differently from their normal siblings in behavioral and learning and memory parameters Horm. Behav. 39 2001 277 284
31. S.E. Kong, R.C. Baxter, and P.J. Delhanty Age-dependent regulation of the acid-labile subunit in response to fasting-refeeding in rats Endocrinology 143 2001 4505 4512
32. P.L. Larsen, P.S. Albert, and D.L. Riddle Genes that regulate both development and longevity in Caenorhabditis elegans Genetics 139 1995 1567 1583
33. W.H. Lee, T.D. Gaylord, R.R. Bowsher, M. Hlaing, H. Moorehead, and F.A. Leichty Nutritional regulation of circulating insulin-like growth factors (IGFs) and their binding proteins in the ovine fetus Endocrin. J. 44 1997 163 173
34. H. Liang, E.J. Masoro, J.F. Nelson, R. Strong, C.A. McMahan, and A. Richardson Genetic mouse models of extended lifespan Exp. Gerontol. 38 2003 1315 1364
35. G. Liu, A.E. Loraine, R. Shigeta, M. Cline, J. Cheng, V. Valmeekam, S. Sun, D. Kulp, and M.A. Siani-Rose NetAffx: Affymetrix probesets and annotations Nucleic Acids Res. 31 2003 82 86
36. M.F. McCarty Up-regulation of IGF binding protein-1 as an anti-carcinogenic strategy: relevance to caloric restriction, exercise, and insulin sensitivity Med. Hypotheses 48 1997 297 308
37. V.T. Mihaylova, C.Z. Borland, L. Manjarrez, M.J. Stern, and H. Sun The PTEN tumor suppressor homolog in Caenorhabditis elegans regulates longevity and dauer formation in an insulin receptor-like signaling pathway Proc. Natl. Acad. Sci. U.S.A. 96 1999 7427 7432
38. C. Minabe-Saegusa, H. Saegusa, M. Tsukahara, and S. Noguchi Sequence and expression of a novel mouse gene PRDC (protein related to DAN and Cerberus) identified by a gene trap approach Dev. Growth Differ. 40 1998 343 353
39. R.A. Miller, Y. Chang, A.T. Galecki, K. Al-Regaiey, J.H. Kopchick, and A. Bartke Gene expression patterns in calorically restricted mice: partial overlap with long-lived mutant mice Mol. Endocrinol. 16 2002 2657 2666
40. J.Z. Morris, H.A. Tissenbaum, and G. Ruvkun A phosphatidylinositol-3-OH kinase family member regulating longevity and diapause in Caenorhabditis elegans Nature 382 1996 536 539
41. T. Okajima, M. Iwashita, Y. Takeda, S. Sakamoto, T. Tanabe, T. Yasuda, and R.G. Rosenfeld Inhibitory effects of insulin-like growth factor (IGF)-binding proteins-1 and -3 on IGF-activated glucose consumption in mouse BALB/c 3T3 fibroblasts J. Endocrinol. 136 1993 457 470
42. S. Ogg, S. Pradis, S. Gottlieb, G.I. Patterson, L. Lee, H.A. Tissenbaum, and G. Ruvkun The Forkhead transcription factor DAF-16 transduces insulin-like metabolic and longevity signals in C. elegans Nature 389 1997 994 999
43. J.S. Parks, M.R. Brown, D.L. Hurley, C.J. Phelps, and M.P. Wajnrajch Heritable disorders of pituitary development J. Clin. Endocrinol. Metab. 84 1999 4362 4370
44. L. Partridge, and D. Gems The evolution of longevity Curr. Biol. 12 2002 544 546
45. J.J. Pearce, G. Penny, and J. Rossant A mouse Cerberus/Dan-related gene family Dev. Biol. 209 1999 98 110
46. M.W. Pfaffl, G.W. Horgan, and L. Dempfle Relative expression software tool (REST) for group-wise comparison and statistical analysis of relatige expression results in real-time PCR Nucleic Acids Res 30 2002 e36
47. F. Poirier, C.T. Chan, P.M. Timmons, E.J. Robertson, M.J. Evans, and P.W. Rigby The murine H19 gene is activated during embryonic stem cell differentiation in vitro and at the time of implantation in the developing embryo Development 113 1991 1105 1114
48. A. Richardson, F. Liu, M.L. Adamo, H.V. Remmen, and J.F. Nelson The role of insulin and insulin-like growth factor-I in mammalian ageing Best Pract. Res. Clin. Endocrinol. Metab. 18 2004 393 406
49. R.P. Rhoads, P.L. Greenwood, A.W. Bell, and Y.R. Boisclair Nutritional regulation of the genes encoding the acid-labile subunit and other components of the circulating insulin-like growth factor system in the sheep J. Anim. Sci 78 2000 2681 2689
50. J.G. Scharf, T. Braulke, H. Hartmann, and G. Ramadori Regulation of the components of the 150 kDa IGF binding protein complex in cocultures of rat hepatocytes and Kupffer cells by 3′, 5′-cyclic adenosine monophosphate J. Cell Physiol. 186 2001 425 436
51. J.G. Scharf, F. Dombrowski, and G. Ramadori The IGF-axis and hepatocarcinogenesis Mol. Pathol. 54 2001 138 144
52. J. Scharf, G. Ramadori, T. Braulke, and H. Hartmann synthesis of insulin-like growth factor binding proteins and of the acid-labile subunit in primary cultures of rat hepatocytes, of Kupffer cells, and in cocultures: regulation by insulin, insulin-like growth factor, and growth hormone Hepatology 23 1996 818 827
53. J.V. Silha, and L.J. Murphy Minireview: insights from insulin-like growth factor binding protein transgenic mice Endocrinology 143 2002 3711 3714
54. S. Sudo, O. Avsian-Kretchmer, L.S. Wang, and A.J. Hsueh Protein related to DAN and Cerberus is a bone morphogenetic p antagonist that participates in ovarian paracrine regulation J. Biol. Chem. 279 2004 23134 23141
55. M. Tatar, A. Kopelman, D. Epstein, M.P. Tu, C.M. Yin, and R.S. Garofalo A mutant drosophila insulin receptor homolog that extends life-span and impairs neuroendocrine function Science 292 2001 41 43
56. M. Tatar, A. Bartke, and A. Antebi The endocrine regulation of aging by insulin-like signals Science 299 2003 1346 1351
57. H.A. Tissenbaum, and G. Ruvkun An insulin-like signaling pathway affects both longevity and reproduction in Caenorhabditis elegans Genetics 148 1998 703 717
58. V.G. Tusher, R. Tibshirani, and G. Chu Significance analysis of microarrays applied to the ionizing radiation response Proc. Natl. Acad. Sci. U.S.A. 98 2001 10515
59. A. Ullrich, A. Gray, A.W. Tam, T. Yang-Feng, M. Tsubokawa, C. Collins, W. Henzel, T. LeBon, S. Kathuria, and E. Chen Insulin-like growth factor I receptor primary structure: comparison with insulin receptor suggests structural determinants that define functional specificity EMBO J. 5 1986 2503 2512
60. J. Vandesompele, K. De Preter, F. Pattyn, B. Poppe, N. Van Roy, A. De Paepe, and F. Speleman Accurate normalization of real-time quantitative RT-PCR data by geometric averaging of multiple internal control genes Genome Biol. 3 2002 RESEARCH0034