-
1
-
-
0033667705
-
Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production
-
Arsenijevic D, Onuma H, Pecqueur C, Raimbault S, Manning BS, Miroux B, Couplan E, Alves-Guerra MC, Goubern M, Surwit R, Bouillaud F, Richard D, Collins S, Ricquier D (2000) Disruption of the uncoupling protein-2 gene in mice reveals a role in immunity and reactive oxygen species production. Nat. Genet. 26, 435-439.
-
(2000)
Nat. Genet.
, vol.26
, pp. 435-439
-
-
Arsenijevic, D.1
Onuma, H.2
Pecqueur, C.3
Raimbault, S.4
Manning, B.S.5
Miroux, B.6
Couplan, E.7
Alves-Guerra, M.C.8
Goubern, M.9
Surwit, R.10
Bouillaud, F.11
Richard, D.12
Collins, S.13
Ricquier, D.14
-
2
-
-
13944278132
-
Mitochondria, oxidants, and aging
-
Balaban RS, Nemoto S, Finkel T (2005) Mitochondria, oxidants, and aging. Cell 120, 483-495.
-
(2005)
Cell
, vol.120
, pp. 483-495
-
-
Balaban, R.S.1
Nemoto, S.2
Finkel, T.3
-
3
-
-
9644262490
-
Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae
-
Barros MH, Bandy B, Tahara EB, Kowaltowski AJ (2004) Higher respiratory activity decreases mitochondrial reactive oxygen release and increases life span in Saccharomyces cerevisiae. J. Biol. Chem. 279, 49883-49888.
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 49883-49888
-
-
Barros, M.H.1
Bandy, B.2
Tahara, E.B.3
Kowaltowski, A.J.4
-
4
-
-
33751072349
-
Resveratrol improves health and survival of mice on a high-calorie diet
-
Baur JA, Pearson KJ, Price NL, Jamieson HA, Lerin C, Kalra A, Prabhu VV, Allard JS, Lopez-Lluch G, Lewis K, Pistell PJ, Poosala S, Becker KG, Boss O, Gwinn D, Wang M, Ramaswamy S, Fishbein KW, Spencer RG, Lakatta EG, Le Couteur D, Shaw RJ, Navas P, Puigserver P, Ingram DK, de Cabo R, Sinclair DA (2006) Resveratrol improves health and survival of mice on a high-calorie diet. Nature 444, 337-342.
-
(2006)
Nature
, vol.444
, pp. 337-342
-
-
Baur, J.A.1
Pearson, K.J.2
Price, N.L.3
Jamieson, H.A.4
Lerin, C.5
Kalra, A.6
Prabhu, V.V.7
Allard, J.S.8
Lopez-Lluch, G.9
Lewis, K.10
Pistell, P.J.11
Poosala, S.12
Becker, K.G.13
Boss, O.14
Gwinn, D.15
Wang, M.16
Ramaswamy, S.17
Fishbein, K.W.18
Spencer, R.G.19
Lakatta, E.G.20
Le Couteur, D.21
Shaw, R.J.22
Navas, P.23
Puigserver, P.24
Ingram, D.K.25
de Cabo, R.26
Sinclair, D.A.27
more..
-
5
-
-
34249891333
-
Two neurons mediate diet-restriction-induced longevity in C. elegans
-
Bishop NA, Guarente L (2007) Two neurons mediate diet-restriction-induced longevity in C. elegans. Nature 447, 545-549.
-
(2007)
Nature
, vol.447
, pp. 545-549
-
-
Bishop, N.A.1
Guarente, L.2
-
6
-
-
33947574775
-
Reduced TOR signalling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression
-
Bonawitz ND, Chatenay-Lapointe M, Pan Y, Shadel GS (2007) Reduced TOR signalling extends chronological life span via increased respiration and upregulation of mitochondrial gene expression. Cell Metab. 5, 265-277.
-
(2007)
Cell Metab.
, vol.5
, pp. 265-277
-
-
Bonawitz, N.D.1
Chatenay-Lapointe, M.2
Pan, Y.3
Shadel, G.S.4
-
7
-
-
0033785071
-
Uncoupling to survive? The role of mitochondrial inefficiency in ageing
-
Brand MD (2000) Uncoupling to survive? The role of mitochondrial inefficiency in ageing. Exp. Gerontol. 35, 811-820.
-
(2000)
Exp. Gerontol.
, vol.35
, pp. 811-820
-
-
Brand, M.D.1
-
8
-
-
33846583673
-
SIR2: A potential target for calorie restriction mimetics
-
Chen D, Guarente L (2007) SIR2: A potential target for calorie restriction mimetics. Trends Mol. Med. 13, 64-71.
-
(2007)
Trends Mol. Med.
, vol.13
, pp. 64-71
-
-
Chen, D.1
Guarente, L.2
-
9
-
-
33745067215
-
Novel neuroprotective, neuritogenic and anti-amyloidogenic properties of 2,4-dinitrophenol: The gentle face of Janus
-
De Felice FG, Ferreira ST (2006) Novel neuroprotective, neuritogenic and anti-amyloidogenic properties of 2,4-dinitrophenol: The gentle face of Janus. IUBMB Life 58, 185-191.
-
(2006)
IUBMB Life
, vol.58
, pp. 185-191
-
-
De Felice, F.G.1
Ferreira, S.T.2
-
10
-
-
27744596999
-
Sir2 blocks extreme life-span extension
-
Fabrizio P, Gattazzo C, Battistella L, Wei M, Cheng C, McGrew K, Longo VD (2005) Sir2 blocks extreme life-span extension. Cell 123, 655-667.
-
(2005)
Cell
, vol.123
, pp. 655-667
-
-
Fabrizio, P.1
Gattazzo, C.2
Battistella, L.3
Wei, M.4
Cheng, C.5
McGrew, K.6
Longo, V.D.7
-
12
-
-
34848816785
-
Effect of long-term caloric restriction on oxygen consumption and body temperature in two different strains of mice
-
Ferguson M, Sohal BH, Forster MJ, Sohal RS (2007) Effect of long-term caloric restriction on oxygen consumption and body temperature in two different strains of mice. Mech. Ageing. Dev. 128, 539-545.
-
(2007)
Mech. Ageing. Dev.
, vol.128
, pp. 539-545
-
-
Ferguson, M.1
Sohal, B.H.2
Forster, M.J.3
Sohal, R.S.4
-
13
-
-
0024455022
-
Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane
-
Fiala ES, Conaway CC, Mathis JE (1989) Oxidative DNA and RNA damage in the livers of Sprague-Dawley rats treated with the hepatocarcinogen 2-nitropropane. Cancer Res. 49, 5518-5522.
-
(1989)
Cancer Res.
, vol.49
, pp. 5518-5522
-
-
Fiala, E.S.1
Conaway, C.C.2
Mathis, J.E.3
-
14
-
-
23944494249
-
Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly
-
Fridell YW, Sánchez-Blanco A, Silvia BA, Helfand SL (2005) Targeted expression of the human uncoupling protein 2 (hUCP2) to adult neurons extends life span in the fly. Cell Metab. 1, 145-152.
-
(2005)
Cell Metab.
, vol.1
, pp. 145-152
-
-
Fridell, Y.W.1
Sánchez-Blanco, A.2
Silvia, B.A.3
Helfand, S.L.4
-
15
-
-
0034717074
-
Lack of obesity and normal response to fasting and thyroid hormone in mice lacking uncoupling protein-3
-
Gong DW, Monemdjou S, Gavrilova O, Leon LR, Marcus-Samuels B, Chou CJ, Everett C, Kozak LP, Li C, Deng C, Harper ME, Reitman ML (2000) Lack of obesity and normal response to fasting and thyroid hormone in mice lacking uncoupling protein-3. J. Biol. Chem. 275, 16251-16257.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 16251-16257
-
-
Gong, D.W.1
Monemdjou, S.2
Gavrilova, O.3
Leon, L.R.4
Marcus-Samuels, B.5
Chou, C.J.6
Everett, C.7
Kozak, L.P.8
Li, C.9
Deng, C.10
Harper, M.E.11
Reitman, M.L.12
-
16
-
-
38649132337
-
Mitochondria - A nexus for aging, calorie restriction, and sirtuins?
-
Guarente L (2008) Mitochondria - a nexus for aging, calorie restriction, and sirtuins? Cell 132, 171-176.
-
(2008)
Cell
, vol.132
, pp. 171-176
-
-
Guarente, L.1
-
17
-
-
0037393466
-
An impairment of phagocytic function is linked to a shorter life span in two strains of prematurely aging mice
-
Guayerbas N, De La Fuente M (2003) An impairment of phagocytic function is linked to a shorter life span in two strains of prematurely aging mice. Dev. Comp. Immunol. 27, 339-350.
-
(2003)
Dev. Comp. Immunol.
, vol.27
, pp. 339-350
-
-
Guayerbas, N.1
De La Fuente, M.2
-
18
-
-
0035502402
-
Mitochondrial uncoupling as a target for drug development for the treatment of obesity
-
Harper JA, Dickinson K, Brand MD (2001) Mitochondrial uncoupling as a target for drug development for the treatment of obesity. Obes. Rev. 2, 255-265.
-
(2001)
Obes. Rev.
, vol.2
, pp. 255-265
-
-
Harper, J.A.1
Dickinson, K.2
Brand, M.D.3
-
19
-
-
0141719702
-
Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan
-
Howitz KT, Bitterman KJ, Cohen HY, Lamming DW, Lavu S, Wood JG, Zipkin RE, Chung P, Kisielewski A, Zhang LL, Scherer B, Sinclair DA (2003) Small molecule activators of sirtuins extend Saccharomyces cerevisiae lifespan. Nature 425, 191-196.
-
(2003)
Nature
, vol.425
, pp. 191-196
-
-
Howitz, K.T.1
Bitterman, K.J.2
Cohen, H.Y.3
Lamming, D.W.4
Lavu, S.5
Wood, J.G.6
Zipkin, R.E.7
Chung, P.8
Kisielewski, A.9
Zhang, L.L.10
Scherer, B.11
Sinclair, D.A.12
-
20
-
-
33847281886
-
DNA damage, a biomarker of carcinogenesis: Its measurement and modulation by diet and environment
-
Hwang ES, Bowen PE (2007) DNA damage, a biomarker of carcinogenesis: Its measurement and modulation by diet and environment. Crit. Rev. Food Sci. Nutr. 47, 27-50.
-
(2007)
Crit. Rev. Food Sci. Nutr.
, vol.47
, pp. 27-50
-
-
Hwang, E.S.1
Bowen, P.E.2
-
21
-
-
33646948539
-
Calorie restriction mimetics: An emerging research field
-
Ingram DK, Zhu M, Mamczarz J, Zou S, Lane MA, Roth GS, deCabo R (2006) Calorie restriction mimetics: An emerging research field. Aging Cell 5, 97-108.
-
(2006)
Aging Cell
, vol.5
, pp. 97-108
-
-
Ingram, D.K.1
Zhu, M.2
Mamczarz, J.3
Zou, S.4
Lane, M.A.5
Roth, G.S.6
deCabo, R.7
-
22
-
-
34249781383
-
'Mild Uncoupling'does not decrease mitochondrial superoxide levels in cultured cerebellar granule neurons but decreases spare respiratory capacity and increases toxicity to glutamate and oxidative stress
-
Johnson-Cadwell LI, Jekabsons MB, Wang A, Polster BM, Nicholls DG (2007) 'Mild Uncoupling'does not decrease mitochondrial superoxide levels in cultured cerebellar granule neurons but decreases spare respiratory capacity and increases toxicity to glutamate and oxidative stress. J. Neurochem. 101, 1619-1631.
-
(2007)
J. Neurochem.
, vol.101
, pp. 1619-1631
-
-
Johnson-Cadwell, L.I.1
Jekabsons, M.B.2
Wang, A.3
Polster, B.M.4
Nicholls, D.G.5
-
23
-
-
20444431507
-
Substrate-specific activation of sirtuins by resveratrol
-
Kaeberlein M, McDonagh T, Heltweg B, Hixon J, Westman EA, Caldwell SD, Napper A, Curtis R, DiStefano PS, Fields S, Bedalov A, Kennedy BK (2005) Substrate-specific activation of sirtuins by resveratrol. J. Biol. Chem. 280, 17038-17045.
-
(2005)
J. Biol. Chem.
, vol.280
, pp. 17038-17045
-
-
Kaeberlein, M.1
McDonagh, T.2
Heltweg, B.3
Hixon, J.4
Westman, E.A.5
Caldwell, S.D.6
Napper, A.7
Curtis, R.8
DiStefano, P.S.9
Fields, S.10
Bedalov, A.11
Kennedy, B.K.12
-
24
-
-
0030729851
-
High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria
-
Korshunov SS, Skulachev VP, Starkov AA (1997) High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. FEBS Lett. 416, 15-18.
-
(1997)
FEBS Lett.
, vol.416
, pp. 15-18
-
-
Korshunov, S.S.1
Skulachev, V.P.2
Starkov, A.A.3
-
26
-
-
0346455761
-
Effect of caloric restriction on mitochondrial reactive oxygen species production and bioenergetics: Reversal by insulin
-
Lambert AJ, Merry BJ (2004) Effect of caloric restriction on mitochondrial reactive oxygen species production and bioenergetics: reversal by insulin. Am. J. Physiol. Regul. Integr. Comp. Physiol. 286, R71-R79.
-
(2004)
Am. J. Physiol. Regul. Integr. Comp. Physiol.
, vol.286
-
-
Lambert, A.J.1
Merry, B.J.2
-
27
-
-
17144402990
-
Lack of effect of caloric restriction on bioenergetics and reactive oxygen species production in intact rat hepatocytes
-
Lambert AJ, Merry BJ (2005) Lack of effect of caloric restriction on bioenergetics and reactive oxygen species production in intact rat hepatocytes. J. Gerontol. A Biol. Sci. Med. Sci. 60, 175-180.
-
(2005)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.60
, pp. 175-180
-
-
Lambert, A.J.1
Merry, B.J.2
-
28
-
-
1342307974
-
The effect of aging and caloric restriction on mitochondrial protein density and oxygen consumption
-
Lambert AJ, Wang B, Yardley J, Edwards J, Merry BJ (2004) The effect of aging and caloric restriction on mitochondrial protein density and oxygen consumption. Exp. Gerontol. 39, 289-295.
-
(2004)
Exp. Gerontol.
, vol.39
, pp. 289-295
-
-
Lambert, A.J.1
Wang, B.2
Yardley, J.3
Edwards, J.4
Merry, B.J.5
-
29
-
-
0032077119
-
Mitogenic factors accelerate later-age diseases: Insulin as a paradigm
-
Lev-Ran A (1998) Mitogenic factors accelerate later-age diseases: insulin as a paradigm. Mech. Ageing. Dev. 102, 95-113.
-
(1998)
Mech. Ageing. Dev.
, vol.102
, pp. 95-113
-
-
Lev-Ran, A.1
-
30
-
-
0034703217
-
Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae
-
Lin SJ, Defossez PA, Guarente L (2000) Requirement of NAD and SIR2 for life-span extension by calorie restriction in Saccharomyces cerevisiae. Science 289, 2126-2128.
-
(2000)
Science
, vol.289
, pp. 2126-2128
-
-
Lin, S.J.1
Defossez, P.A.2
Guarente, L.3
-
31
-
-
0037130175
-
Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration
-
Lin SJ, Kaeberlein M, Andalis AA, Sturtz LA, Defossez PA, Culotta VC, Fink GR, Guarente L (2002) Calorie restriction extends Saccharomyces cerevisiae lifespan by increasing respiration. Nature 418, 344-348.
-
(2002)
Nature
, vol.418
, pp. 344-348
-
-
Lin, S.J.1
Kaeberlein, M.2
Andalis, A.A.3
Sturtz, L.A.4
Defossez, P.A.5
Culotta, V.C.6
Fink, G.R.7
Guarente, L.8
-
32
-
-
35148890391
-
Mitochondrial uncouplers with an extraordinary dynamic range
-
Lou PH, Hansen BS, Olsen PH, Tullin S, Murphy MP, Brand MD (2007) Mitochondrial uncouplers with an extraordinary dynamic range. Biochem. J. 407, 129-140.
-
(2007)
Biochem. J.
, vol.407
, pp. 129-140
-
-
Lou, P.H.1
Hansen, B.S.2
Olsen, P.H.3
Tullin, S.4
Murphy, M.P.5
Brand, M.D.6
-
34
-
-
23644434842
-
Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells
-
MacLellan JD, Gerrits MF, Gowing A, Smith PJ, Wheeler MB, Harper ME (2005) Physiological increases in uncoupling protein 3 augment fatty acid oxidation and decrease reactive oxygen species production without uncoupling respiration in muscle cells. Diabetes 54, 2343-2350.
-
(2005)
Diabetes
, vol.54
, pp. 2343-2350
-
-
MacLellan, J.D.1
Gerrits, M.F.2
Gowing, A.3
Smith, P.J.4
Wheeler, M.B.5
Harper, M.E.6
-
35
-
-
3342891368
-
Oxidative stress and mitochondrial function with aging - The effects of calorie restriction
-
Merry BJ (2004) Oxidative stress and mitochondrial function with aging - the effects of calorie restriction. Aging Cell 3, 7-12.
-
(2004)
Aging Cell
, vol.3
, pp. 7-12
-
-
Merry, B.J.1
-
36
-
-
33745898848
-
Dietary antioxidants and beneficial effect on oxidatively damaged DNA
-
Møller P, Loft S (2006) Dietary antioxidants and beneficial effect on oxidatively damaged DNA. Free Radic. Biol. Med. 41, 388-415.
-
(2006)
Free Radic. Biol. Med.
, vol.41
, pp. 388-415
-
-
Møller, P.1
Loft, S.2
-
37
-
-
0038061012
-
A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation
-
Nègre-Salvayre A, Hirtz C, Carrera G, Cazenave R, Troly M, Salvayre R, Pénicaud L, Casteilla L (1997) A role for uncoupling protein-2 as a regulator of mitochondrial hydrogen peroxide generation. FASEB J. 11, 809-815.
-
(1997)
FASEB J.
, vol.11
, pp. 809-815
-
-
Nègre-Salvayre, A.1
Hirtz, C.2
Carrera, G.3
Cazenave, R.4
Troly, M.5
Salvayre, R.6
Pénicaud, L.7
Casteilla, L.8
-
38
-
-
0347579845
-
Mitochondrial biogenesis in mammals: The role of endogenous nitric oxide
-
Nisoli E, Clementi E, Paolucci C, Cozzi V, Tonello C, Sciorati C, Bracale R, Valerio A, Francolini M, Moncada S, Carruba MO (2003) Mitochondrial biogenesis in mammals: The role of endogenous nitric oxide. Science 299, 896-899.
-
(2003)
Science
, vol.299
, pp. 896-899
-
-
Nisoli, E.1
Clementi, E.2
Paolucci, C.3
Cozzi, V.4
Tonello, C.5
Sciorati, C.6
Bracale, R.7
Valerio, A.8
Francolini, M.9
Moncada, S.10
Carruba, M.O.11
-
39
-
-
26844558334
-
Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS
-
Nisoli E, Tonello C, Cardile A, Cozzi V, Bracale R, Tedesco L, Falcone S, Valerio A, Cantoni O, Clementi E, Moncada S, Carruba MO (2005) Calorie restriction promotes mitochondrial biogenesis by inducing the expression of eNOS. Science 310, 314-317.
-
(2005)
Science
, vol.310
, pp. 314-317
-
-
Nisoli, E.1
Tonello, C.2
Cardile, A.3
Cozzi, V.4
Bracale, R.5
Tedesco, L.6
Falcone, S.7
Valerio, A.8
Cantoni, O.9
Clementi, E.10
Moncada, S.11
Carruba, M.O.12
-
40
-
-
26844520762
-
Uncoupler of oxidative phosphorylation prolongs the lifespan of Drosophila
-
Padalko VI (2005) Uncoupler of oxidative phosphorylation prolongs the lifespan of Drosophila. Biochemistry (Mosc) 70, 986-989.
-
(2005)
Biochemistry (Mosc)
, vol.70
, pp. 986-989
-
-
Padalko, V.I.1
-
41
-
-
0016271265
-
Dinitrophenol and bioenergetics: An historical perspective
-
Parascandola J (1974) Dinitrophenol and bioenergetics: An historical perspective. Mol. Cell. Biochem. 5, 69-77.
-
(1974)
Mol. Cell. Biochem.
, vol.5
, pp. 69-77
-
-
Parascandola, J.1
-
42
-
-
0036245337
-
Mechanisms of ageing: Public or private?
-
Partridge L, Gems D (2002) Mechanisms of ageing: Public or private? Nat. Rev. Genet. 3, 165-175.
-
(2002)
Nat. Rev. Genet.
, vol.3
, pp. 165-175
-
-
Partridge, L.1
Gems, D.2
-
43
-
-
0034650763
-
The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP
-
Ricquier D, Bouillaud F (2000) The uncoupling protein homologues: UCP1, UCP2, UCP3, StUCP and AtUCP. Biochem. J. 345, 161-179.
-
(2000)
Biochem. J.
, vol.345
, pp. 161-179
-
-
Ricquier, D.1
Bouillaud, F.2
-
44
-
-
4444281969
-
Aging in rhesus monkeys: Relevance to human health interventions
-
Roth GS, Mattison JA, Ottinger MA, Chachich ME, Lane MA, Ingram DK (2004) Aging in rhesus monkeys: Relevance to human health interventions. Science 305, 1423-1426.
-
(2004)
Science
, vol.305
, pp. 1423-1426
-
-
Roth, G.S.1
Mattison, J.A.2
Ottinger, M.A.3
Chachich, M.E.4
Lane, M.A.5
Ingram, D.K.6
-
45
-
-
21144434217
-
Extension of murine life span by overexpression of catalase targeted to mitochondria
-
Schriner SE, Linford NJ, Martin GM, Treuting P, Ogburn CE, Emond M, Coskun PE, Ladiges W, Wolf N, Van Remmen H, Wallace DC, Rabinovitch PS (2005) Extension of murine life span by overexpression of catalase targeted to mitochondria. Science 308, 1909-1911.
-
(2005)
Science
, vol.308
, pp. 1909-1911
-
-
Schriner, S.E.1
Linford, N.J.2
Martin, G.M.3
Treuting, P.4
Ogburn, C.E.5
Emond, M.6
Coskun, P.E.7
Ladiges, W.8
Wolf, N.9
Van Remmen, H.10
Wallace, D.C.11
Rabinovitch, P.S.12
-
46
-
-
0028143826
-
Differential susceptibility of plasma proteins to oxidative modification: Examination by western blot immunoassay
-
Shacter E, Williams JA, Lim M, Levine RL (1994) Differential susceptibility of plasma proteins to oxidative modification: Examination by western blot immunoassay. Free Radic. Biol. Med. 17, 429-437.
-
(1994)
Free Radic. Biol. Med.
, vol.17
, pp. 429-437
-
-
Shacter, E.1
Williams, J.A.2
Lim, M.3
Levine, R.L.4
-
47
-
-
0029765443
-
Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants
-
Skulachev VP (1996) Role of uncoupled and non-coupled oxidations in maintenance of safely low levels of oxygen and its one-electron reductants. Q. Rev. Biophys. 29, 169-202.
-
(1996)
Q. Rev. Biophys.
, vol.29
, pp. 169-202
-
-
Skulachev, V.P.1
-
48
-
-
0032564864
-
Uncoupling: New approaches to an old problem of bioenergetics
-
Skulachev VP (1998) Uncoupling: New approaches to an old problem of bioenergetics. Biochim. Biophys. Acta 1363, 100-124.
-
(1998)
Biochim. Biophys. Acta
, vol.1363
, pp. 100-124
-
-
Skulachev, V.P.1
-
49
-
-
37648998990
-
A biochemical approach to the problem of aging: 'Megaproject'on membrane-penetrating ions. The first results and prospects
-
Skulachev VP (2007) A biochemical approach to the problem of aging: 'megaproject'on membrane-penetrating ions. The first results and prospects. Biochemistry (Mosc) 72, 1385-1396.
-
(2007)
Biochemistry (Mosc)
, vol.72
, pp. 1385-1396
-
-
Skulachev, V.P.1
-
50
-
-
0030038103
-
Oxidative stress, caloric restriction, and aging
-
Sohal RS, Weindruch R (1996) Oxidative stress, caloric restriction, and aging. Science 273, 59-63.
-
(1996)
Science
, vol.273
, pp. 59-63
-
-
Sohal, R.S.1
Weindruch, R.2
-
51
-
-
7044239977
-
Uncoupled and surviving: Individual mice with high metabolism have greater mitochondrial uncoupling and live longer
-
Speakman JR, Talbot DA, Selman C, Snart S, McLaren JS, Redman P, Krol E, Jackson DM, Johnson MS, Brand MD (2004) Uncoupled and surviving: individual mice with high metabolism have greater mitochondrial uncoupling and live longer. Aging Cell 3, 87-95.
-
(2004)
Aging Cell
, vol.3
, pp. 87-95
-
-
Speakman, J.R.1
Talbot, D.A.2
Selman, C.3
Snart, S.4
McLaren, J.S.5
Redman, P.6
Krol, E.7
Jackson, D.M.8
Johnson, M.S.9
Brand, M.D.10
-
52
-
-
4544359913
-
Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species
-
Starkov AA, Fiskum G, Chinopoulos C, Lorenzo BJ, Browne SE, Patel MS, Beal MF (2004) Mitochondrial alpha-ketoglutarate dehydrogenase complex generates reactive oxygen species. J. Neurosci. 24, 7779-7788.
-
(2004)
J. Neurosci.
, vol.24
, pp. 7779-7788
-
-
Starkov, A.A.1
Fiskum, G.2
Chinopoulos, C.3
Lorenzo, B.J.4
Browne, S.E.5
Patel, M.S.6
Beal, M.F.7
-
53
-
-
13844266312
-
No evidence of mitochondrial respiratory dysfunction in OGG1-null mice deficient in removal of 8-oxodeoxyguanine from mitochondrial DNA
-
Stuart JA, Bourque BM, de Souza-Pinto NC, Bohr VA (2005) No evidence of mitochondrial respiratory dysfunction in OGG1-null mice deficient in removal of 8-oxodeoxyguanine from mitochondrial DNA. Free Radic. Biol. Med. 38, 737-745.
-
(2005)
Free Radic. Biol. Med.
, vol.38
, pp. 737-745
-
-
Stuart, J.A.1
Bourque, B.M.2
de Souza-Pinto, N.C.3
Bohr, V.A.4
-
54
-
-
33845999916
-
Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging
-
Tahara EB, Barros MH, Oliveira GA, Netto LES, Kowaltowski AJ (2007) Dihydrolipoyl dehydrogenase as a source of reactive oxygen species inhibited by caloric restriction and involved in Saccharomyces cerevisiae aging. FASEB J. 21, 274-283.
-
(2007)
FASEB J.
, vol.21
, pp. 274-283
-
-
Tahara, E.B.1
Barros, M.H.2
Oliveira, G.A.3
Netto, L.E.S.4
Kowaltowski, A.J.5
-
55
-
-
34047151226
-
Life extension through neurofibromin mitochondrial regulation and antioxidant therapy for neurofibromatosis-1 in Drosophila melanogaster
-
Tong JJ, Schriner SE, McCleary D, Day BJ, Wallace DC (2007) Life extension through neurofibromin mitochondrial regulation and antioxidant therapy for neurofibromatosis-1 in Drosophila melanogaster. Nat. Genet. 39, 476-485.
-
(2007)
Nat. Genet.
, vol.39
, pp. 476-485
-
-
Tong, J.J.1
Schriner, S.E.2
McCleary, D.3
Day, B.J.4
Wallace, D.C.5
-
56
-
-
4544226082
-
Generation of reactive oxygen species in the reaction catalyzed by α-ketoglutarate dehydrogenase
-
Tretter L, Adam-Vizi V (2004) Generation of reactive oxygen species in the reaction catalyzed by α-ketoglutarate dehydrogenase. J. Neurosci. 24, 7771-7778.
-
(2004)
J. Neurosci.
, vol.24
, pp. 7771-7778
-
-
Tretter, L.1
Adam-Vizi, V.2
-
57
-
-
0142150051
-
Mitochondrial formation of reactive oxygen species
-
Turrens JF (2003) Mitochondrial formation of reactive oxygen species. J. Physiol. 552, 335-344.
-
(2003)
J. Physiol.
, vol.552
, pp. 335-344
-
-
Turrens, J.F.1
-
58
-
-
4444384541
-
Genetic control of lifespan: Studies from animal models
-
Van Zant G, de Haan G (1999) Genetic control of lifespan: Studies from animal models. Expert Rev. Mol. Med. 1999, 1-12.
-
(1999)
Expert Rev. Mol. Med.
, vol.1999
, pp. 1-12
-
-
Van Zant, G.1
de Haan, G.2
-
59
-
-
0036265323
-
Calorie restriction in biosphere 2: Alterations in physiologic, hematologic, hormonal, and biochemical parameters in humans restricted for a 2-year period
-
Walford RL, Mock D, Verdery R, MacCallum T (2002) Calorie restriction in biosphere 2: Alterations in physiologic, hematologic, hormonal, and biochemical parameters in humans restricted for a 2-year period. J. Gerontol. A Biol. Sci. Med. Sci. 57, B211-B224.
-
(2002)
J. Gerontol. A Biol. Sci. Med. Sci.
, vol.57
-
-
Walford, R.L.1
Mock, D.2
Verdery, R.3
MacCallum, T.4
-
60
-
-
0028306912
-
Purification of genomic DNA from human whole blood by isopropanol-fractionation with concentrated NaI and SDS
-
Wang L, Hirayasu K, Ishizawa M, Kobayashi Y (1994) Purification of genomic DNA from human whole blood by isopropanol-fractionation with concentrated NaI and SDS. Nucleic Acids Res. 22, 1774-1775.
-
(1994)
Nucleic Acids Res.
, vol.22
, pp. 1774-1775
-
-
Wang, L.1
Hirayasu, K.2
Ishizawa, M.3
Kobayashi, Y.4
-
61
-
-
2942598147
-
Expression of lung uncoupling protein-2 mRNA is modulated developmentally and by caloric intake
-
Xiao H, Massaro D, Massaro GD, Clerch LB (2004) Expression of lung uncoupling protein-2 mRNA is modulated developmentally and by caloric intake. Exp. Biol. Med. 229, 479-485.
-
(2004)
Exp. Biol. Med.
, vol.229
, pp. 479-485
-
-
Xiao, H.1
Massaro, D.2
Massaro, G.D.3
Clerch, L.B.4
-
62
-
-
0031573401
-
A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: Applications in detecting the activity of phagocyte NADPH oxidase and other oxidases
-
Zhou M, Diwu Z, Panchuk-Voloshina N, Haugland RP (1997) A stable nonfluorescent derivative of resorufin for the fluorometric determination of trace hydrogen peroxide: Applications in detecting the activity of phagocyte NADPH oxidase and other oxidases. Anal. Biochem. 253, 162-168.
-
(1997)
Anal. Biochem.
, vol.253
, pp. 162-168
-
-
Zhou, M.1
Diwu, Z.2
Panchuk-Voloshina, N.3
Haugland, R.P.4
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