-
1
-
-
0033573156
-
Internal regulation of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes
-
Ainscow EK and Brand MD. Internal regulation of ATP turnover, glycolysis and oxidative phosphorylation in rat hepatocytes. Eur J Biochem 266: 737-749, 1999.
-
(1999)
Eur J Biochem
, vol.266
, pp. 737-749
-
-
Ainscow, E.K.1
Brand, M.D.2
-
2
-
-
0033231404
-
The responses of rat hepatocytes to glucagon and adrenaline. Application of quantified elasticity analysis
-
Ainscow EK and Brand MD. The responses of rat hepatocytes to glucagon and adrenaline. Application of quantified elasticity analysis. Eur J Biochem 265: 1043-1055, 1999.
-
(1999)
Eur J Biochem
, vol.265
, pp. 1043-1055
-
-
Ainscow, E.K.1
Brand, M.D.2
-
3
-
-
0033179481
-
Top-down control analysis of ATP turn-over, glycolysis and oxidative phosphorylation in rat hepatocytes
-
Ainscow EK and Brand MD. Top-down control analysis of ATP turn-over, glycolysis and oxidative phosphorylation in rat hepatocytes. Eur J Biochem 263: 671-685, 1999.
-
(1999)
Eur J Biochem
, vol.263
, pp. 671-685
-
-
Ainscow, E.K.1
Brand, M.D.2
-
4
-
-
0035936147
-
Extending the lifespan of long-lived mice
-
Bartke A, Wright JC, Mattison JA, Ingram DK, Miller RA, and Roth GS. Extending the lifespan of long-lived mice. Nature 414: 412, 2001.
-
(2001)
Nature
, vol.414
, pp. 412
-
-
Bartke, A.1
Wright, J.C.2
Mattison, J.A.3
Ingram, D.K.4
Miller, R.A.5
Roth, G.S.6
-
5
-
-
0037942739
-
Extended longevity in mice lacking the insulin receptor in adipose tissue
-
Bluher M, Kahn BB, and Kahn CR. Extended longevity in mice lacking the insulin receptor in adipose tissue. Science 299: 572-574, 2003.
-
(2003)
Science
, vol.299
, pp. 572-574
-
-
Bluher, M.1
Kahn, B.B.2
Kahn, C.R.3
-
6
-
-
0002114258
-
Measurement of mitochondrial protonmotive force
-
edited by Brown GC and Cooper CE. Oxford: IRL
-
Brand MD. Measurement of mitochondrial protonmotive force. In: Bioenergetics: A Practical Approach, edited by Brown GC and Cooper CE. Oxford: IRL, 1995, p. 39-62.
-
(1995)
Bioenergetics: A Practical Approach
, pp. 39-62
-
-
Brand, M.D.1
-
7
-
-
0030574107
-
Top down metabolic control analysis
-
Brand MD. Top down metabolic control analysis. J Theor Biol 182: 351-360, 1996.
-
(1996)
J Theor Biol
, vol.182
, pp. 351-360
-
-
Brand, M.D.1
-
8
-
-
0037353433
-
Caloric restriction promotes genomic stability by induction of base excision repair and reversal of its age-related decline
-
Cabelof DC, Yanamadala S, Raffoul JJ, Guo Z, Soofi A, and Heydari AR. Caloric restriction promotes genomic stability by induction of base excision repair and reversal of its age-related decline. DNA Repair (Amst) 2: 295-307, 2003.
-
(2003)
DNA Repair (Amst)
, vol.2
, pp. 295-307
-
-
Cabelof, D.C.1
Yanamadala, S.2
Raffoul, J.J.3
Guo, Z.4
Soofi, A.5
Heydari, A.R.6
-
9
-
-
0033796250
-
Mitochondrial free radical generation, oxidative stress, and aging
-
Cadenas E and Davies KJ. Mitochondrial free radical generation, oxidative stress, and aging. Free Radic Biol Med 29: 222-230, 2000.
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 222-230
-
-
Cadenas, E.1
Davies, K.J.2
-
10
-
-
0035815414
-
Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein
-
Clancy DJ, Gems D, Harshman LG, Oldham S, Stocker H, Hafen E, Leevers SJ, and Partridge L. Extension of life-span by loss of CHICO, a Drosophila insulin receptor substrate protein. Science 292: 104-106, 2001.
-
(2001)
Science
, vol.292
, pp. 104-106
-
-
Clancy, D.J.1
Gems, D.2
Harshman, L.G.3
Oldham, S.4
Stocker, H.5
Hafen, E.6
Leevers, S.J.7
Partridge, L.8
-
11
-
-
0036037678
-
Control analysis of DNA microarray expression data
-
Curtis RK and Brand MD. Control analysis of DNA microarray expression data. Mol Biol Rep 29: 67-71, 2002.
-
(2002)
Mol Biol Rep
, vol.29
, pp. 67-71
-
-
Curtis, R.K.1
Brand, M.D.2
-
12
-
-
0030248727
-
Influences of age and dietary restriction on gastrocnemius electron transport system activities in mice
-
Desai VG, Weindruch R, Hart RW, and Feuers RJ. Influences of age and dietary restriction on gastrocnemius electron transport system activities in mice. Arch Biochem Biophys 333: 145-151, 1996.
-
(1996)
Arch Biochem Biophys
, vol.333
, pp. 145-151
-
-
Desai, V.G.1
Weindruch, R.2
Hart, R.W.3
Feuers, R.J.4
-
13
-
-
0035979492
-
Caloric restriction alters the feeding response of key metabolic enzyme genes
-
Dhahbi JM, Mote PL, Wingo J, Rowley BC, Cao SX, Walford RL, and Spindler SR. Caloric restriction alters the feeding response of key metabolic enzyme genes. Mech Ageing Dev 122: 1033-1048, 2001.
-
(2001)
Mech Ageing Dev
, vol.122
, pp. 1033-1048
-
-
Dhahbi, J.M.1
Mote, P.L.2
Wingo, J.3
Rowley, B.C.4
Cao, S.X.5
Walford, R.L.6
Spindler, S.R.7
-
14
-
-
0037305488
-
Effects of aging and caloric restriction on mitochondrial energy production in gastrocnemius muscle and heart
-
Drew B, Phaneuf S, Dirks A, Selman C, Gredilla R, Lezza A, Barja G, and Leeuwenburgh C. Effects of aging and caloric restriction on mitochondrial energy production in gastrocnemius muscle and heart. Am J Physiol Regul Integr Comp Physiol 284: R474-R480, 2003.
-
(2003)
Am J Physiol Regul Integr Comp Physiol
, vol.284
-
-
Drew, B.1
Phaneuf, S.2
Dirks, A.3
Selman, C.4
Gredilla, R.5
Lezza, A.6
Barja, G.7
Leeuwenburgh, C.8
-
15
-
-
18244379331
-
Superoxide activates mitochondrial uncoupling proteins
-
Echtay KS, Roussel D, St-Pierre J, Jekabsons MB, Cadenas S, Stuart JA, Harper JA, Roebuck SJ, Morrison A, Pickering S, Clapham JC, and Brand MD. Superoxide activates mitochondrial uncoupling proteins. Nature 415: 96-99, 2002.
-
(2002)
Nature
, vol.415
, pp. 96-99
-
-
Echtay, K.S.1
Roussel, D.2
St-Pierre, J.3
Jekabsons, M.B.4
Cadenas, S.5
Stuart, J.A.6
Harper, J.A.7
Roebuck, S.J.8
Morrison, A.9
Pickering, S.10
Clapham, J.C.11
Brand, M.D.12
-
17
-
-
0035403165
-
Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart
-
Gredilla R, Sanz A, Lopez-Torres M, and Barja G. Caloric restriction decreases mitochondrial free radical generation at complex I and lowers oxidative damage to mitochondrial DNA in the rat heart. FASEB J 15: 1589-1591, 2001.
-
(2001)
FASEB J
, vol.15
, pp. 1589-1591
-
-
Gredilla, R.1
Sanz, A.2
Lopez-Torres, M.3
Barja, G.4
-
18
-
-
0025238864
-
Analysis of the control of respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the 'top-down' approach of metabolic control theory
-
Hafner RP, Brown GC, and Brand MD. Analysis of the control of respiration rate, phosphorylation rate, proton leak rate and protonmotive force in isolated mitochondria using the 'top-down' approach of metabolic control theory. Eur J Biochem 188: 313-319, 1990.
-
(1990)
Eur J Biochem
, vol.188
, pp. 313-319
-
-
Hafner, R.P.1
Brown, G.C.2
Brand, M.D.3
-
20
-
-
0028915135
-
Use of top-down elasticity analysis to identify sites of thyroid hormone-induced thermogenesis
-
Harper ME and Brand MD. Use of top-down elasticity analysis to identify sites of thyroid hormone-induced thermogenesis. Proc Soc Exp Biol Med 208: 228-237, 1995.
-
(1995)
Proc Soc Exp Biol Med
, vol.208
, pp. 228-237
-
-
Harper, M.E.1
Brand, M.D.2
-
21
-
-
0031869858
-
Age-related increase in mitochondrial proton leak and decrease in ATP turn-over reactions in mouse hepatocytes
-
Harper ME, Monemdjou S, Ramsey JJ, and Weindruch R. Age-related increase in mitochondrial proton leak and decrease in ATP turn-over reactions in mouse hepatocytes. Am J Physiol Endocrinol Metab 275: E197-E206, 1998.
-
(1998)
Am J Physiol Endocrinol Metab
, vol.275
-
-
Harper, M.E.1
Monemdjou, S.2
Ramsey, J.J.3
Weindruch, R.4
-
22
-
-
0347664057
-
IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice
-
Holzenberger M, Dupont J, Ducos B, Leneuve P, Geloen A, Even PC, Cervera P, and Le Bouc Y. IGF-1 receptor regulates lifespan and resistance to oxidative stress in mice. Nature 421: 182-187, 2003.
-
(2003)
Nature
, vol.421
, pp. 182-187
-
-
Holzenberger, M.1
Dupont, J.2
Ducos, B.3
Leneuve, P.4
Geloen, A.5
Even, P.C.6
Cervera, P.7
Le Bouc, Y.8
-
23
-
-
0036103401
-
Implications for the insulin signaling pathway in Snell dwarf mouse longevity: A similarity with the C. elegans longevity paradigm
-
Hsieh CC, DeFord JH, Flurkey K, Harrison DE, and Papaconstantinou J. Implications for the insulin signaling pathway in Snell dwarf mouse longevity: a similarity with the C. elegans longevity paradigm. Mech Ageing Dev 123: 1229-1244, 2002.
-
(2002)
Mech Ageing Dev
, vol.123
, pp. 1229-1244
-
-
Hsieh, C.C.1
DeFord, J.H.2
Flurkey, K.3
Harrison, D.E.4
Papaconstantinou, J.5
-
25
-
-
0024242627
-
Effect of diet restriction on glucose metabolism and insulin responsiveness in aging rats
-
Kalant N, Stewart J, and Kaplan R. Effect of diet restriction on glucose metabolism and insulin responsiveness in aging rats. Mech Ageing Dev 46: 89-104, 1988.
-
(1988)
Mech Ageing Dev
, vol.46
, pp. 89-104
-
-
Kalant, N.1
Stewart, J.2
Kaplan, R.3
-
26
-
-
0033963434
-
Calcium regulation of oxidative phosphorylation in rat skeletal muscle mitochondria
-
Kavanagh NI, Ainscow EK, and Brand MD. Calcium regulation of oxidative phosphorylation in rat skeletal muscle mitochondria. Biochim Biophys Acta 1457: 57-70, 2000.
-
(2000)
Biochim Biophys Acta
, vol.1457
, pp. 57-70
-
-
Kavanagh, N.I.1
Ainscow, E.K.2
Brand, M.D.3
-
27
-
-
0028072088
-
Effects of cadmium on the control and internal regulation of oxidative phosphorylation in potato tuber mitochondria
-
Kesseler A and Brand MD. Effects of cadmium on the control and internal regulation of oxidative phosphorylation in potato tuber mitochondria. Eur J Biochem 225: 907-922, 1994.
-
(1994)
Eur J Biochem
, vol.225
, pp. 907-922
-
-
Kesseler, A.1
Brand, M.D.2
-
28
-
-
0028034024
-
Localisation of the sites of action of cadmium on oxidative phosphorylation in potato tuber mitochondria using top-down elasticity analysis
-
Kesseler A and Brand MD. Localisation of the sites of action of cadmium on oxidative phosphorylation in potato tuber mitochondria using top-down elasticity analysis. Eur J Biochem 225: 897-906, 1994.
-
(1994)
Eur J Biochem
, vol.225
, pp. 897-906
-
-
Kesseler, A.1
Brand, M.D.2
-
29
-
-
0028029801
-
Quantitative determination of the regulation of oxidative phosphorylation by cadmium in potato tuber mitochondria
-
Kesseler A and Brand MD. Quantitative determination of the regulation of oxidative phosphorylation by cadmium in potato tuber mitochondria. Eur J Biochem 225: 923-935, 1994.
-
(1994)
Eur J Biochem
, vol.225
, pp. 923-935
-
-
Kesseler, A.1
Brand, M.D.2
-
30
-
-
0030729851
-
High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria
-
Korshunov SS, Skulachev VP, and Starkov AA. High protonic potential actuates a mechanism of production of reactive oxygen species in mitochondria. FEBS Lett 416: 15-18, 1997.
-
(1997)
FEBS Lett
, vol.416
, pp. 15-18
-
-
Korshunov, S.S.1
Skulachev, V.P.2
Starkov, A.A.3
-
31
-
-
0033674460
-
Quantitation of signal transduction
-
Krauss S and Brand MD. Quantitation of signal transduction. FASEB J 14: 2581-2588, 2000.
-
(2000)
FASEB J
, vol.14
, pp. 2581-2588
-
-
Krauss, S.1
Brand, M.D.2
-
32
-
-
0035118947
-
Effects of caloric restriction on skeletal muscle mitochondrial proton leak in aging rats
-
Lal SB, Ramsey JJ, Monemdjou S, Weindruch R, and Harper ME. Effects of caloric restriction on skeletal muscle mitochondrial proton leak in aging rats. J Gerontol A Biol Sci Med Sci 56: B116-122, 2001.
-
(2001)
J Gerontol A Biol Sci Med Sci
, vol.56
-
-
Lal, S.B.1
Ramsey, J.J.2
Monemdjou, S.3
Weindruch, R.4
Harper, M.E.5
-
33
-
-
0034253571
-
Use of primary cultures of rat hepatocytes for the study of ageing and caloric restriction
-
Lambert AJ and Merry BJ. Use of primary cultures of rat hepatocytes for the study of ageing and caloric restriction. Exp Gerontol 35: 583-594, 2000.
-
(2000)
Exp Gerontol
, vol.35
, pp. 583-594
-
-
Lambert, A.J.1
Merry, B.J.2
-
34
-
-
0030722043
-
Generating, partitioning, targeting and functioning of superoxide in mitochondria
-
Liu SS. Generating, partitioning, targeting and functioning of superoxide in mitochondria. Biosci Rep 17: 259-272, 1997.
-
(1997)
Biosci Rep
, vol.17
, pp. 259-272
-
-
Liu, S.S.1
-
35
-
-
0034674761
-
Characterization of oxidative phosphorylation in skeletal muscle mitochondria subpopulations in pig: A study using top-down elasticity analysis
-
Lombardi A, Damon M, Vincent A, Goglia F, and Herpin P. Characterization of oxidative phosphorylation in skeletal muscle mitochondria subpopulations in pig: a study using top-down elasticity analysis. FEBS Lett 475: 84-88, 2000.
-
(2000)
FEBS Lett
, vol.475
, pp. 84-88
-
-
Lombardi, A.1
Damon, M.2
Vincent, A.3
Goglia, F.4
Herpin, P.5
-
36
-
-
0036569788
-
Influence of aging and long-term caloric restriction on oxygen radical generation and oxidative DNA damage in rat liver mitochondria
-
Lopez-Torres M, Gredilla R, Sanz A, and Barja G. Influence of aging and long-term caloric restriction on oxygen radical generation and oxidative DNA damage in rat liver mitochondria. Free Radic Biol Med 32: 882-889, 2002.
-
(2002)
Free Radic Biol Med
, vol.32
, pp. 882-889
-
-
Lopez-Torres, M.1
Gredilla, R.2
Sanz, A.3
Barja, G.4
-
37
-
-
0035966052
-
Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes
-
Mahadev K, Wu X, Zilbering A, Zhu L, Lawrence JT, and Goldstein BJ. Hydrogen peroxide generated during cellular insulin stimulation is integral to activation of the distal insulin signaling cascade in 3T3-L1 adipocytes. J Biol Chem 276: 48662-48669, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 48662-48669
-
-
Mahadev, K.1
Wu, X.2
Zilbering, A.3
Zhu, L.4
Lawrence, J.T.5
Goldstein, B.J.6
-
38
-
-
0024462136
-
Transient reduction of metabolic rate by food restriction
-
McCarter RJ and McGee JR. Transient reduction of metabolic rate by food restriction. Am J Physiol Endocrinol Metab 257: E175-E179, 1989.
-
(1989)
Am J Physiol Endocrinol Metab
, vol.257
-
-
McCarter, R.J.1
McGee, J.R.2
-
39
-
-
0005121775
-
Calorie restriction and age-related oxidative stress
-
edited by Toussaint O, Osiewacz HD, Lithgow GJ, and Brack C. New York: New York Academy of Science
-
Merry BJ. Calorie restriction and age-related oxidative stress. In: Molecular and Cellular Gerontology, edited by Toussaint O, Osiewacz HD, Lithgow GJ, and Brack C. New York: New York Academy of Science, 2002, p. 180-198.
-
(2002)
Molecular and Cellular Gerontology
, pp. 180-198
-
-
Merry, B.J.1
-
40
-
-
0036828603
-
Molecular mechanisms linking calorie restriction and longevity
-
Merry BJ. Molecular mechanisms linking calorie restriction and longevity. Int J Biochem Cell Biol 34: 1340-1354, 2002.
-
(2002)
Int J Biochem Cell Biol
, vol.34
, pp. 1340-1354
-
-
Merry, B.J.1
-
41
-
-
0018199057
-
Preparation and characterization of mitochondria and submitochondrial particles of rat liver and liver-derived tissues
-
Pedersen PL, Greenawalt JW, Reynafarje B, Hullihen J, Decker GL, Soper JW, and Bustamente E. Preparation and characterization of mitochondria and submitochondrial particles of rat liver and liver-derived tissues. Methods Cell Biol 20: 411-481, 1978.
-
(1978)
Methods Cell Biol
, vol.20
, pp. 411-481
-
-
Pedersen, P.L.1
Greenawalt, J.W.2
Reynafarje, B.3
Hullihen, J.4
Decker, G.L.5
Soper, J.W.6
Bustamente, E.7
-
43
-
-
0028342438
-
Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse
-
Sohal RS, Ku HH, Agarwal S, Forster MJ, and Lal H. Oxidative damage, mitochondrial oxidant generation and antioxidant defenses during aging and in response to food restriction in the mouse. Mech Ageing Dev 74: 121-133, 1994.
-
(1994)
Mech Ageing Dev
, vol.74
, pp. 121-133
-
-
Sohal, R.S.1
Ku, H.H.2
Agarwal, S.3
Forster, M.J.4
Lal, H.5
-
44
-
-
0036132431
-
Caloric restriction and lifespan: A role for protein turnover?
-
Tavernarakis N and Driscoll M. Caloric restriction and lifespan: a role for protein turnover? Mech Ageing Dev 123: 215-229, 2002.
-
(2002)
Mech Ageing Dev
, vol.123
, pp. 215-229
-
-
Tavernarakis, N.1
Driscoll, M.2
-
45
-
-
0034988397
-
Oxidative damage to mitochondria and aging
-
Van Remmen H and Richardson A. Oxidative damage to mitochondria and aging. Exp Gerontol 36: 957-968, 2001.
-
(2001)
Exp Gerontol
, vol.36
, pp. 957-968
-
-
Van Remmen, H.1
Richardson, A.2
-
47
-
-
0019186034
-
Modification of mitochondrial respiration by aging and dietary restriction
-
Weindruch RH, Cheung MK, Verity MA, and Walford RL. Modification of mitochondrial respiration by aging and dietary restriction. Mech Ageing Dev 12: 375-392, 1980.
-
(1980)
Mech Ageing Dev
, vol.12
, pp. 375-392
-
-
Weindruch, R.H.1
Cheung, M.K.2
Verity, M.A.3
Walford, R.L.4
-
48
-
-
0034613164
-
Regulation of C elegans life-span by insulin like signaling in the nervous system
-
Wolkow CA, Kimura KD, Lee MS, and Ruvkun G. Regulation of C elegans life-span by insulin like signaling in the nervous system. Science 290: 147-150, 2000.
-
(2000)
Science
, vol.290
, pp. 147-150
-
-
Wolkow, C.A.1
Kimura, K.D.2
Lee, M.S.3
Ruvkun, G.4
|