-
1
-
-
0031195028
-
Mitogen-activated protein kinase cascades and the signaling of hyperosmotic stress to immediate early genes
-
Cohen DM. Mitogen-activated protein kinase cascades and the signaling of hyperosmotic stress to immediate early genes. Comp Biochem Physiol 1997;117:291-9.
-
(1997)
Comp Biochem Physiol
, vol.117
, pp. 291-299
-
-
Cohen, D.M.1
-
2
-
-
0037032817
-
Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases
-
Johnson GL, Lapadat R. Mitogen-activated protein kinase pathways mediated by ERK, JNK, and p38 protein kinases. Science 2002;298:1911-2.
-
(2002)
Science
, vol.298
, pp. 1911-1912
-
-
Johnson, G.L.1
Lapadat, R.2
-
4
-
-
0033758633
-
Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis Arthritis
-
Schett G, Tohidast-Akrad M, Smolen JS, Schmid BJ, Steiner CW, Bitzan P, et al. Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis Arthritis Rheum 2000;43:2501-12.
-
(2000)
Rheum
, vol.43
, pp. 2501-2512
-
-
Schett, G.1
Tohidast-Akrad, M.2
Smolen, J.S.3
Schmid, B.J.4
Steiner, C.W.5
Bitzan, P.6
-
5
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee JC, Laydon JT, McDonnell PC, Gallagher TF, Kumar S, Green D, et al. A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994;372:739-46.
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
-
6
-
-
0029983730
-
The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor
-
Beyaert R, Cuenda A, Vanden Berghe W, Plaisance S, Lee JC, Haegeman G, et al. The p38/RK mitogen-activated protein kinase pathway regulates interleukin-6 synthesis response to tumor necrosis factor. EMBO J 1996;15:1914-23.
-
(1996)
EMBO J
, vol.15
, pp. 1914-1923
-
-
Beyaert, R.1
Cuenda, A.2
Vanden Berghe, W.3
Plaisance, S.4
Lee, J.C.5
Haegeman, G.6
-
7
-
-
0034785749
-
Roles of tumor necrosis factor p55 and p75 receptors in TNF-alpha-induced vascular permeability
-
Ferrero E, Zocchi MR, Magni E, Panzeri MC, Curnis F, Rugarli C, et al. Roles of tumor necrosis factor p55 and p75 receptors in TNF-alpha-induced vascular permeability. Am J Physiol Cell Physiol 2001;281:C1173-9.
-
(2001)
Am J Physiol Cell Physiol
, vol.281
-
-
Ferrero, E.1
Zocchi, M.R.2
Magni, E.3
Panzeri, M.C.4
Curnis, F.5
Rugarli, C.6
-
8
-
-
25144518584
-
Tumour necrosis factor activates the mitogen-activated protein kinases p38alpha and ERK in the synovial membrane in vivo
-
Gortz B, Hayer S, Tuerck B, Zwerina J, Smolen JS, Schett G. Tumour necrosis factor activates the mitogen-activated protein kinases p38alpha and ERK in the synovial membrane in vivo. Arthritis Res Ther 2005;7:R1140-7.
-
(2005)
Arthritis Res Ther
, vol.7
-
-
Gortz, B.1
Hayer, S.2
Tuerck, B.3
Zwerina, J.4
Smolen, J.S.5
Schett, G.6
-
10
-
-
0037126628
-
Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1
-
Kassel O, Sancono A, Kratzschmar J, Kreft B, Stassen M, Cato AC. Glucocorticoids inhibit MAP kinase via increased expression and decreased degradation of MKP-1. EMBO J 2001;20:7108-16.
-
(2001)
EMBO J
, vol.20
, pp. 7108-7116
-
-
Kassel, O.1
Sancono, A.2
Kratzschmar, J.3
Kreft, B.4
Stassen, M.5
Cato, A.C.6
-
11
-
-
0036841288
-
Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38
-
Lasa M, Abraham SM, Boucheron C, Saklatvala J, Clark AR. Dexamethasone causes sustained expression of mitogen-activated protein kinase (MAPK) phosphatase 1 and phosphatase-mediated inhibition of MAPK p38. Mol Cell Biol 2002;22:7802-11.
-
(2002)
Mol Cell Biol
, vol.22
, pp. 7802-7811
-
-
Lasa, M.1
Abraham, S.M.2
Boucheron, C.3
Saklatvala, J.4
Clark, A.R.5
-
12
-
-
5644230846
-
Expression of mitogen-activated protein kinase phosphatase 1, a negative regulator of the mitogen-activated protein kinases, in rheumatoid arthritis: Up-regulation by interleukin-1beta and glucocorticoids
-
Toh ML, Yang Y, Leech M, Santos L, Morand EF. Expression of mitogen-activated protein kinase phosphatase 1, a negative regulator of the mitogen-activated protein kinases, in rheumatoid arthritis: up-regulation by interleukin-1beta and glucocorticoids. Arthritis Rheum 2004;50:3118-28.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3118-3128
-
-
Toh, M.L.1
Yang, Y.2
Leech, M.3
Santos, L.4
Morand, E.F.5
-
14
-
-
0035281564
-
Regulation of gene expression by the small GTPase Rho through the ERK6 (p38 gamma) MAP kinase pathway
-
Marinissen MJ, Chiariello M, Gutkind JS. Regulation of gene expression by the small GTPase Rho through the ERK6 (p38 gamma) MAP kinase pathway. Genes Dev 2001;15:535-53.
-
(2001)
Genes Dev
, vol.15
, pp. 535-553
-
-
Marinissen, M.J.1
Chiariello, M.2
Gutkind, J.S.3
-
15
-
-
33644811654
-
Small GTP-binding protein Rho-mediated signaling promotes proliferation of rheumatoid synovial fibroblasts
-
Nakayamada S, Kurose H, Saito K, Mogami A, Tanaka Y. Small GTP-binding protein Rho-mediated signaling promotes proliferation of rheumatoid synovial fibroblasts. Arthritis Res Ther 2005;7:476-84.
-
(2005)
Arthritis Res Ther
, vol.7
, pp. 476-484
-
-
Nakayamada, S.1
Kurose, H.2
Saito, K.3
Mogami, A.4
Tanaka, Y.5
-
16
-
-
0035667628
-
Activated Ras modifies the proliferative response of rheumatoid synovial cells to TNF-alpha and TGF-alpha
-
Kitasato H, Noda M, Akahoshi T, Okamoto R, Koshino T, Murakami Y, et al. Activated Ras modifies the proliferative response of rheumatoid synovial cells to TNF-alpha and TGF-alpha. Inflamm Res 2001;50:592-7.
-
(2001)
Inflamm Res
, vol.50
, pp. 592-597
-
-
Kitasato, H.1
Noda, M.2
Akahoshi, T.3
Okamoto, R.4
Koshino, T.5
Murakami, Y.6
-
17
-
-
0141564912
-
Suppression of arthritic bone destruction by adenovirus-mediated dominant-negative Ras gene transfer to synoviocytes and osteoclasts
-
Yamamoto A, Fukuda A, Seto H, Miyazaki T, Kadono Y, Sawada Y, et al. Suppression of arthritic bone destruction by adenovirus-mediated dominant-negative Ras gene transfer to synoviocytes and osteoclasts. Arthritis Rheum 2003;48:2682-92.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2682-2692
-
-
Yamamoto, A.1
Fukuda, A.2
Seto, H.3
Miyazaki, T.4
Kadono, Y.5
Sawada, Y.6
-
18
-
-
0029862818
-
Oncoprotein expression in human synovial tissue: An immunohistochemical study of different types of arthritis
-
Roivainen A, Soderstrom KO, Pirila L, Aro H, Kortekangas P, Merilahti-Palo R, et al. Oncoprotein expression in human synovial tissue: an immunohistochemical study of different types of arthritis. Br J Rheumatol 1996;35:933-42.
-
(1996)
Br J Rheumatol
, vol.35
, pp. 933-942
-
-
Roivainen, A.1
Soderstrom, K.O.2
Pirila, L.3
Aro, H.4
Kortekangas, P.5
Merilahti-Palo, R.6
-
19
-
-
0028670788
-
Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1
-
Yan M, Dai T, Deak JC, Kyriakis JM, Zon LI, Woodgett JR, et al. Activation of stress-activated protein kinase by MEKK1 phosphorylation of its activator SEK1. Nature 1994;372:798-800.
-
(1994)
Nature
, vol.372
, pp. 798-800
-
-
Yan, M.1
Dai, T.2
Deak, J.C.3
Kyriakis, J.M.4
Zon, L.I.5
Woodgett, J.R.6
-
20
-
-
0029913457
-
Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase
-
Blank JL, Gerwins P, Elliott EM, Sather S, Johnson GL. Molecular cloning of mitogen-activated protein/ERK kinase kinases (MEKK) 2 and 3. Regulation of sequential phosphorylation pathways involving mitogen-activated protein kinase and c-Jun kinase. J Biol Chem 1996;271:5361-8.
-
(1996)
J Biol Chem
, vol.271
, pp. 5361-5368
-
-
Blank, J.L.1
Gerwins, P.2
Elliott, E.M.3
Sather, S.4
Johnson, G.L.5
-
21
-
-
0030934694
-
Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway
-
Gerwins P, Blank JL, Johnson GL. Cloning of a novel mitogen-activated protein kinase kinase kinase, MEKK4, that selectively regulates the c-Jun amino terminal kinase pathway. J Biol Chem 1997;272:8288-95.
-
(1997)
J Biol Chem
, vol.272
, pp. 8288-8295
-
-
Gerwins, P.1
Blank, J.L.2
Johnson, G.L.3
-
22
-
-
1642444091
-
Regulation of c-Jun N-terminal kinase by MEKK-2 and mitogen-activated protein kinase kinase kinases in rheumatoid arthritis
-
Hammaker DR, Boyle DL, Chabaud-Riou M, Firestein GS. Regulation of c-Jun N-terminal kinase by MEKK-2 and mitogen-activated protein kinase kinase kinases in rheumatoid arthritis. J Immunol 2004;172:1612-8.
-
(2004)
J Immunol
, vol.172
, pp. 1612-1618
-
-
Hammaker, D.R.1
Boyle, D.L.2
Chabaud-Riou, M.3
Firestein, G.S.4
-
23
-
-
14444281569
-
Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways
-
Ichijo H, Nishida E, Irie K, ten Dijke P, Saitoh M, Moriguchi T, et al. Induction of apoptosis by ASK1, a mammalian MAPKKK that activates SAPK/JNK and p38 signaling pathways. Science 1997;275:90-4.
-
(1997)
Science
, vol.275
, pp. 90-94
-
-
Ichijo, H.1
Nishida, E.2
Irie, K.3
ten Dijke, P.4
Saitoh, M.5
Moriguchi, T.6
-
24
-
-
0030851904
-
A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways
-
Takekawa M, Posas F, Saito H. A human homolog of the yeast Ssk2/Ssk22 MAP kinase kinase kinases, MTK1, mediates stress-induced activation of the p38 and JNK pathways. EMBO J 1997;16:4973-82.
-
(1997)
EMBO J
, vol.16
, pp. 4973-4982
-
-
Takekawa, M.1
Posas, F.2
Saito, H.3
-
25
-
-
0029551805
-
Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction
-
Yamaguchi K, Shirakabe K, Shibuya H, lrie K, Oishi I, Ueno N, et al. Identification of a member of the MAPKKK family as a potential mediator of TGF-beta signal transduction. Science 1995;270:2008- 11.
-
(1995)
Science
, vol.270
, pp. 2008-2011
-
-
Yamaguchi, K.1
Shirakabe, K.2
Shibuya, H.3
lrie, K.4
Oishi, I.5
Ueno, N.6
-
26
-
-
0029764111
-
Dual leucine zipper-bearing kinase (DLK) activates p46SAPK and p38mapk but not ERK2
-
Fan G, Merritt SE, Kortenjann M, Shaw PE, Holzman LB. Dual leucine zipper-bearing kinase (DLK) activates p46SAPK and p38mapk but not ERK2. J Biol Chem 1996;271:24788-93.
-
(1996)
J Biol Chem
, vol.271
, pp. 24788-24793
-
-
Fan, G.1
Merritt, S.E.2
Kortenjann, M.3
Shaw, P.E.4
Holzman, L.B.5
-
27
-
-
0030875602
-
MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42
-
Fanger GR, Johnson NL, Johnson GL. MEK kinases are regulated by EGF and selectively interact with Rac/Cdc42. EMBO J 1997;16:4961- 72.
-
(1997)
EMBO J
, vol.16
, pp. 4961-4972
-
-
Fanger, G.R.1
Johnson, N.L.2
Johnson, G.L.3
-
28
-
-
0033598783
-
c-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation
-
Cong F, Goff SP. c-Abl-induced apoptosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation. Proc Natl Acad Sci USA 1999;96:13819-24.
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13819-13824
-
-
Cong, F.1
Goff, S.P.2
-
29
-
-
0033118982
-
Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice
-
Lu HT, Yang DD, Wysk M, Gatti E, Mellman I, Davis RJ, et al. Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice. EMBO J 1999;18:1845-57.
-
(1999)
EMBO J
, vol.18
, pp. 1845-1857
-
-
Lu, H.T.1
Yang, D.D.2
Wysk, M.3
Gatti, E.4
Mellman, I.5
Davis, R.J.6
-
30
-
-
0036687249
-
Differential involvement of p38 mitogen-activated protein kinase kinases MKK3 and MKK6 in T-cell apoptosis
-
Tanaka N, Kamanaka M, Enslen H, Dong C, Wysk M, Davis RJ, et al. Differential involvement of p38 mitogen-activated protein kinase kinases MKK3 and MKK6 in T-cell apoptosis. EMBO Rep 2002;3:785-91.
-
(2002)
EMBO Rep
, vol.3
, pp. 785-791
-
-
Tanaka, N.1
Kamanaka, M.2
Enslen, H.3
Dong, C.4
Wysk, M.5
Davis, R.J.6
-
31
-
-
33645765290
-
Mitogen-activated protein kinase kinase 3 is a pivotal pathway regulating p38 activation in inflammatory arthritis
-
Inoue T, Boyle DL, Corr M, Hammaker D, Davis RJ, Flavell RA, et al. Mitogen-activated protein kinase kinase 3 is a pivotal pathway regulating p38 activation in inflammatory arthritis. Proc Natl Acad Sci USA 2006;103:5484-9.
-
(2006)
Proc Natl Acad Sci USA
, vol.103
, pp. 5484-5489
-
-
Inoue, T.1
Boyle, D.L.2
Corr, M.3
Hammaker, D.4
Davis, R.J.5
Flavell, R.A.6
-
32
-
-
10244241798
-
Purification and identification of a major activator for p38 from osmotically shocked cells. Activation of mitogen-activated protein kinase kinase 6 by osmotic shock, tumor necrosis factor-alpha, and H2O2
-
Moriguchi T, Toyoshirna F, Gotoh Y, Iwamatsu A, Irie K, Mori E, et al. Purification and identification of a major activator for p38 from osmotically shocked cells. Activation of mitogen-activated protein kinase kinase 6 by osmotic shock, tumor necrosis factor-alpha, and H2O2. J Biol Chem 1996;271:26981-8.
-
(1996)
J Biol Chem
, vol.271
, pp. 26981-26988
-
-
Moriguchi, T.1
Toyoshirna, F.2
Gotoh, Y.3
Iwamatsu, A.4
Irie, K.5
Mori, E.6
-
33
-
-
1542784431
-
Expression and activation of mitogen-activated protein kinase kinases-3 and -6 in rheumatoid arthritis
-
Chabaud-Riou M, Firestein GS. Expression and activation of mitogen-activated protein kinase kinases-3 and -6 in rheumatoid arthritis. Am J Pathol 2004;164:177-84.
-
(2004)
Am J Pathol
, vol.164
, pp. 177-184
-
-
Chabaud-Riou, M.1
Firestein, G.S.2
-
34
-
-
20244385583
-
CD44 is a determinant of inflammatory bone loss
-
Hayer S, Steiner G, Gortz B, Reiter E, Tohidast-Akrad M, Amling M, et al. CD44 is a determinant of inflammatory bone loss. J Exp Med 2005;201:903-14.
-
(2005)
J Exp Med
, vol.201
, pp. 903-914
-
-
Hayer, S.1
Steiner, G.2
Gortz, B.3
Reiter, E.4
Tohidast-Akrad, M.5
Amling, M.6
-
35
-
-
0032212557
-
Purification and activation of recombinant p38 isoforms alpha, beta, gamma, and delta
-
Keesler GA, Bray J, Hunt J, Johnson DA, Gleason T, Yao Z, et al. Purification and activation of recombinant p38 isoforms alpha, beta, gamma, and delta. Protein Expr Purif 1998;14:221-8.
-
(1998)
Protein Expr Purif
, vol.14
, pp. 221-228
-
-
Keesler, G.A.1
Bray, J.2
Hunt, J.3
Johnson, D.A.4
Gleason, T.5
Yao, Z.6
-
36
-
-
0033120590
-
Differential expression and activation of p38 mitogen-activated protein kinase alpha, beta, gamma, and delta in inflammatory cell lineages
-
Hale KK, Trollinger D, Rihanek M, Manthey CL. Differential expression and activation of p38 mitogen-activated protein kinase alpha, beta, gamma, and delta in inflammatory cell lineages. J Immunol 1999;162:4246-52.
-
(1999)
J Immunol
, vol.162
, pp. 4246-4252
-
-
Hale, K.K.1
Trollinger, D.2
Rihanek, M.3
Manthey, C.L.4
-
37
-
-
0029982565
-
Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta)
-
Jiang Y, Chen C, Li Z, Guo W, Gegner JA, Lin S, et al. Characterization of the structure and function of a new mitogen-activated protein kinase (p38beta). J Biol Chem 1996;271:17920-6.
-
(1996)
J Biol Chem
, vol.271
, pp. 17920-17926
-
-
Jiang, Y.1
Chen, C.2
Li, Z.3
Guo, W.4
Gegner, J.A.5
Lin, S.6
-
38
-
-
0029911710
-
ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation
-
Lechner C, Zahalka MA, Giot JF, Moller NP, Ullrich A. ERK6, a mitogen-activated protein kinase involved in C2C12 myoblast differentiation. Proc Natl Acad Sci USA 1996;93:4355-9.
-
(1996)
Proc Natl Acad Sci USA
, vol.93
, pp. 4355-4359
-
-
Lechner, C.1
Zahalka, M.A.2
Giot, J.F.3
Moller, N.P.4
Ullrich, A.5
-
39
-
-
0031024646
-
Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38)
-
Cuenda A, Cohen P, Buee-Scherrer V, Goedert M. Activation of stress-activated protein kinase-3 (SAPK3) by cytokines and cellular stresses is mediated via SAPKK3 (MKK6); comparison of the specificities of SAPK3 and SAPK2 (RK/p38). EMBO J 1997;16:295-305.
-
(1997)
EMBO J
, vol.16
, pp. 295-305
-
-
Cuenda, A.1
Cohen, P.2
Buee-Scherrer, V.3
Goedert, M.4
-
40
-
-
0030828701
-
Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta
-
Jiang Y, Gram H, Zhao M, New L, Gu J, Feng L, et al. Characterization of the structure and function of the fourth member of p38 group mitogen-activated protein kinases, p38delta. J Biol Chem 1997;272:30122-8.
-
(1997)
J Biol Chem
, vol.272
, pp. 30122-30128
-
-
Jiang, Y.1
Gram, H.2
Zhao, M.3
New, L.4
Gu, J.5
Feng, L.6
-
41
-
-
0030756286
-
Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase
-
Wang XS, Diener K, Manthey CL, Wang S, Rosenzweig B, Bray J, et al. Molecular cloning and characterization of a novel p38 mitogen-activated protein kinase. J Biol Chem 1997;272:23668-74.
-
(1997)
J Biol Chem
, vol.272
, pp. 23668-23674
-
-
Wang, X.S.1
Diener, K.2
Manthey, C.L.3
Wang, S.4
Rosenzweig, B.5
Bray, J.6
-
42
-
-
0034653850
-
Molecular determinants that mediate selective activation of p38 MAP kinase isoforms
-
Enslen H, Brancho DM, Davis RJ. Molecular determinants that mediate selective activation of p38 MAP kinase isoforms. EMBO J 2000;19:1301-11.
-
(2000)
EMBO J
, vol.19
, pp. 1301-1311
-
-
Enslen, H.1
Brancho, D.M.2
Davis, R.J.3
-
43
-
-
0031916832
-
Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6
-
Enslen H, Raingeaud J, Davis RJ. Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6. J Biol Chem 1998;273:1741-8.
-
(1998)
J Biol Chem
, vol.273
, pp. 1741-1748
-
-
Enslen, H.1
Raingeaud, J.2
Davis, R.J.3
-
44
-
-
0031587929
-
Novel homologues of CSBP/p38 MAP kinase: Activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles
-
Kumar S, McDonnell PC, Gum RJ, Hand AT, Lee JC, Young PR. Novel homologues of CSBP/p38 MAP kinase: activation, substrate specificity and sensitivity to inhibition by pyridinyl imidazoles. Biochem Biophys Res Commun 1997;235:533-8.
-
(1997)
Biochem Biophys Res Commun
, vol.235
, pp. 533-538
-
-
Kumar, S.1
McDonnell, P.C.2
Gum, R.J.3
Hand, A.T.4
Lee, J.C.5
Young, P.R.6
-
45
-
-
0034541591
-
Retrotransposable L1 elemts expressed in rheumatoid arthritis synovial tissue, association with genomic hypomethylation and influence on gene expression
-
Neidhart M, Rethage J, Kuchen S, Kunzler P, Crowl RM, Billingham ME, et al. Retrotransposable L1 elemts expressed in rheumatoid arthritis synovial tissue, association with genomic hypomethylation and influence on gene expression. Arthritis Rheum 2000;43:2634-47.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2634-2647
-
-
Neidhart, M.1
Rethage, J.2
Kuchen, S.3
Kunzler, P.4
Crowl, R.M.5
Billingham, M.E.6
-
46
-
-
0034945841
-
Heterogeneity of the signal transduction pathways for VEGF-induced MAPKs activation in human vascular endothelial cells
-
Yashima R, Abe M, Tanaka K, Ueno H, Shitara K, Takenoshita S, et al. Heterogeneity of the signal transduction pathways for VEGF-induced MAPKs activation in human vascular endothelial cells. J Cell Physiol 2001;188:201-10.
-
(2001)
J Cell Physiol
, vol.188
, pp. 201-210
-
-
Yashima, R.1
Abe, M.2
Tanaka, K.3
Ueno, H.4
Shitara, K.5
Takenoshita, S.6
-
47
-
-
0033520376
-
p38 mitogen-activated protein kinase is involved in Fas ligand expression
-
Hsu SC, Gavrilin MA, Tsai MH, Han J, Lai MZ. p38 mitogen-activated protein kinase is involved in Fas ligand expression. J Biol Chem 1999;274:25769-76.
-
(1999)
J Biol Chem
, vol.274
, pp. 25769-25776
-
-
Hsu, S.C.1
Gavrilin, M.A.2
Tsai, M.H.3
Han, J.4
Lai, M.Z.5
-
48
-
-
0033559424
-
Selective activation and functional significance of p38alpha mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils
-
Nick JA, Avdi NJ, Young SK, Lehman LA, McDonald PP, Frasch SC, et al. Selective activation and functional significance of p38alpha mitogen-activated protein kinase in lipopolysaccharide-stimulated neutrophils. J Clin Invest 1999;103:851-8.
-
(1999)
J Clin Invest
, vol.103
, pp. 851-858
-
-
Nick, J.A.1
Avdi, N.J.2
Young, S.K.3
Lehman, L.A.4
McDonald, P.P.5
Frasch, S.C.6
-
49
-
-
0034936994
-
Expression of hypoxia-inducible factor 1alpha by macrophages in the rheumatoid synovium: Implications for targeting of therapeutic genes to the inflamed joint
-
Hollander AP, Corke KP, Freemont AJ, Lewis CE. Expression of hypoxia-inducible factor 1alpha by macrophages in the rheumatoid synovium: implications for targeting of therapeutic genes to the inflamed joint. Arthritis Rheum 2001;44:1540-4.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 1540-1544
-
-
Hollander, A.P.1
Corke, K.P.2
Freemont, A.J.3
Lewis, C.E.4
-
50
-
-
27944461325
-
Generation and characterization of p38beta (MAPK11) gene-targeted mice
-
Beardmore VA, Hinton HJ, Eftychi C, Apostolaki M, Armaka M, Darragh J, et al. Generation and characterization of p38beta (MAPK11) gene-targeted mice. Mol Cell Biol 2005;25:10454-64.
-
(2005)
Mol Cell Biol
, vol.25
, pp. 10454-10464
-
-
Beardmore, V.A.1
Hinton, H.J.2
Eftychi, C.3
Apostolaki, M.4
Armaka, M.5
Darragh, J.6
-
51
-
-
9744269944
-
The discovery of orally active triaminotriazine aniline amides as inhibitors of p38 MAP kinase
-
Leftheris K, Ahmed G, Chan R, Dyckman AJ, Hussain Z, Ho K, et al. The discovery of orally active triaminotriazine aniline amides as inhibitors of p38 MAP kinase. J Med Chem 2004;47:6283-91.
-
(2004)
J Med Chem
, vol.47
, pp. 6283-6291
-
-
Leftheris, K.1
Ahmed, G.2
Chan, R.3
Dyckman, A.J.4
Hussain, Z.5
Ho, K.6
-
52
-
-
3142677902
-
The development of novel inhibitors of tumor necrosis factor-alpha (TNF-alpha) production based on substituted [5,5]-bicyclic pyrazolones
-
Laufersweiler MJ, Brugel TA, Clark MP, Golebiowski A, Bookland RG, Laughlin SK, et al. The development of novel inhibitors of tumor necrosis factor-alpha (TNF-alpha) production based on substituted [5,5]-bicyclic pyrazolones. Bioorg Med Chem Lett 2004;14:4267-72.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, pp. 4267-4272
-
-
Laufersweiler, M.J.1
Brugel, T.A.2
Clark, M.P.3
Golebiowski, A.4
Bookland, R.G.5
Laughlin, S.K.6
-
53
-
-
10744219681
-
Benzimidazolone p38 inhibitors
-
Dombroski MA, Letavic MA, McClure KF, Barberia JT, Carty TJ, Cortina SR, et al. Benzimidazolone p38 inhibitors. Bioorg Med Chem Lett 2004;14:919-23.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, pp. 919-923
-
-
Dombroski, M.A.1
Letavic, M.A.2
McClure, K.F.3
Barberia, J.T.4
Carty, T.J.5
Cortina, S.R.6
-
54
-
-
33644883681
-
Discovery of S-[5-amino-1-(4-fluorophenyl)-1H- pyrazol-4-yl-]-[3-(2,3-dihydroxypropoxy)phenyl]methanone (R03201195), an orally bioavailable and highly selective inhibtor for p38 MAP kinase
-
Goldstein DM, Alfredson T, Bertrand J, Browner MF, Clifford K, Dalrymple SA, et al. Discovery of S-[5-amino-1-(4-fluorophenyl)-1H- pyrazol-4-yl-]-[3-(2,3-dihydroxypropoxy)phenyl]methanone (R03201195), an orally bioavailable and highly selective inhibtor for p38 MAP kinase. J Med Chem 2006;49:1562-75.
-
(2006)
J Med Chem
, vol.49
, pp. 1562-1575
-
-
Goldstein, D.M.1
Alfredson, T.2
Bertrand, J.3
Browner, M.F.4
Clifford, K.5
Dalrymple, S.A.6
-
55
-
-
0345803000
-
Alterations in subcellular localization of p38 MAPK potentiates endothelin-stimulated COX-2 expression in glomerular mesangial cells
-
Pratt PF, Bokemeyer D, Foschi M, Sorokin A, Dunn MJ. Alterations in subcellular localization of p38 MAPK potentiates endothelin-stimulated COX-2 expression in glomerular mesangial cells. J Biol Chem 2003;278:51928-36.
-
(2003)
J Biol Chem
, vol.278
, pp. 51928-51936
-
-
Pratt, P.F.1
Bokemeyer, D.2
Foschi, M.3
Sorokin, A.4
Dunn, M.J.5
-
56
-
-
0035854673
-
A Novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38 alpha and beta MAPKs
-
Tanoue T, Yamamoto T, Maeda R, Nishida E. A Novel MAPK phosphatase MKP-7 acts preferentially on JNK/SAPK and p38 alpha and beta MAPKs. J Biol Chem 2001;276:26629-39
-
(2001)
J Biol Chem
, vol.276
, pp. 26629-26639
-
-
Tanoue, T.1
Yamamoto, T.2
Maeda, R.3
Nishida, E.4
-
57
-
-
4644296075
-
Histone deacetylase 3, a class I histone deacetylase, suppresses MAPK11-mediated activating transcription factor-2 activation and represses TNF gene expression
-
Mahlknecht U, Will J, Varin A, Hoelzer D, Herbein G. Histone deacetylase 3, a class I histone deacetylase, suppresses MAPK11-mediated activating transcription factor-2 activation and represses TNF gene expression. J Immunol 2004;173:3979-90.
-
(2004)
J Immunol
, vol.173
, pp. 3979-3990
-
-
Mahlknecht, U.1
Will, J.2
Varin, A.3
Hoelzer, D.4
Herbein, G.5
-
58
-
-
0032544234
-
Regulation of interleukin-1 beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase
-
Miyazawa K, Mori A, Miyata H, Akahane M, Ajisawa Y, Okudaira H. Regulation of interleukin-1 beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase. J Biol Chem 1998;273:24832-8.
-
(1998)
J Biol Chem
, vol.273
, pp. 24832-24838
-
-
Miyazawa, K.1
Mori, A.2
Miyata, H.3
Akahane, M.4
Ajisawa, Y.5
Okudaira, H.6
-
59
-
-
0030826361
-
The stathmin/tubulin interaction in vitro
-
Curmi PA, Andersen SS, Lachkar S, Gavet O, Karsenti E, Knossow M, et al. The stathmin/tubulin interaction in vitro. J Biol Chem 1997;272:25029-36
-
(1997)
J Biol Chem
, vol.272
, pp. 25029-25036
-
-
Curmi, P.A.1
Andersen, S.S.2
Lachkar, S.3
Gavet, O.4
Karsenti, E.5
Knossow, M.6
-
60
-
-
0033617341
-
Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition
-
Hasegawa M, Cuenda A, Spillantini MG, Thomas GM, Buee-Scherrer V, Cohen P, et al. Stress-activated protein kinase-3 interacts with the PDZ domain of alpha1-syntrophin. A mechanism for specific substrate recognition. J Biol Chem 1999;274:12626-31.
-
(1999)
J Biol Chem
, vol.274
, pp. 12626-12631
-
-
Hasegawa, M.1
Cuenda, A.2
Spillantini, M.G.3
Thomas, G.M.4
Buee-Scherrer, V.5
Cohen, P.6
-
61
-
-
0037200088
-
Activation of p38 alpha MAPK enhances collagenase-1 (matrix metalloproteinase (MMP)-1) and stromelysin-1 (MMP-3) expression by mRNA stabilization
-
Reunanen N, Li SP, Ahonen M, Foschi M, Han J, Kahari VM. Activation of p38 alpha MAPK enhances collagenase-1 (matrix metalloproteinase (MMP)-1) and stromelysin-1 (MMP-3) expression by mRNA stabilization. J Biol Chem 2002;277:32360-8.
-
(2002)
J Biol Chem
, vol.277
, pp. 32360-32368
-
-
Reunanen, N.1
Li, S.P.2
Ahonen, M.3
Foschi, M.4
Han, J.5
Kahari, V.M.6
-
62
-
-
23444437384
-
Heat shock protein-70 mediates the cytoprotective effect of carbon monoxide: Involvement of p38 beta MAPK and heat shock factor-1
-
Kim HP, Wang X, Zhang J, Suh GY, Benjamin IJ, Ryter SW, et al. Heat shock protein-70 mediates the cytoprotective effect of carbon monoxide: involvement of p38 beta MAPK and heat shock factor-1. J Immunol 2005;175:2622-9.
-
(2005)
J Immunol
, vol.175
, pp. 2622-2629
-
-
Kim, H.P.1
Wang, X.2
Zhang, J.3
Suh, G.Y.4
Benjamin, I.J.5
Ryter, S.W.6
-
63
-
-
0032569019
-
Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase
-
Nemoto S, Xiang J, Huang S, Lin A. Induction of apoptosis by SB202190 through inhibition of p38beta mitogen-activated protein kinase. J Biol Chem 1998;273:16415-20.
-
(1998)
J Biol Chem
, vol.273
, pp. 16415-16420
-
-
Nemoto, S.1
Xiang, J.2
Huang, S.3
Lin, A.4
-
64
-
-
2442637022
-
Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2
-
Sabio G, Reuver S, Feijoo C, Hasegawa M, Thomas GM, Centeno F, et al. Stress- and mitogen-induced phosphorylation of the synapse-associated protein SAP90/PSD-95 by activation of SAPK3/p38gamma and ERK1/ERK2. Biochem J 2004;380:19-30.
-
(2004)
Biochem J
, vol.380
, pp. 19-30
-
-
Sabio, G.1
Reuver, S.2
Feijoo, C.3
Hasegawa, M.4
Thomas, G.M.5
Centeno, F.6
-
65
-
-
0141557549
-
A regulatory role for p38 delta MAPK in keratinocyte differentiation. Evidence for p38 delta-ERK1/2 complex formation
-
Efimova T, Broome AM, Eckert RL. A regulatory role for p38 delta MAPK in keratinocyte differentiation. Evidence for p38 delta-ERK1/2 complex formation. J Biol Chem 2003;278:34277-85.
-
(2003)
J Biol Chem
, vol.278
, pp. 34277-34285
-
-
Efimova, T.1
Broome, A.M.2
Eckert, R.L.3
-
66
-
-
33749370145
-
Differential tissue expression and activation of p38 MAPK alpha, beta, gamma, and delta isoforms in rheumatoid arthritis
-
Korb A, Tohidast-Akrad M, Cetin E, Axmann R, Smolen J, Schett G. Differential tissue expression and activation of p38 MAPK alpha, beta, gamma, and delta isoforms in rheumatoid arthritis. Arthritis Rheum 2006;54:2745-56.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 2745-2756
-
-
Korb, A.1
Tohidast-Akrad, M.2
Cetin, E.3
Axmann, R.4
Smolen, J.5
Schett, G.6
-
67
-
-
32444438052
-
Activation of p38 MAPK is a key step in tumor necrosis factor-mediated inflammatory bone destruction
-
Zwerina J, Hayer S, Redlich K, Bobacz K, Kollias G, Smolen JS, et al. Activation of p38 MAPK is a key step in tumor necrosis factor-mediated inflammatory bone destruction. Arthritis Rheum 2006;54:463-72.
-
(2006)
Arthritis Rheum
, vol.54
, pp. 463-472
-
-
Zwerina, J.1
Hayer, S.2
Redlich, K.3
Bobacz, K.4
Kollias, G.5
Smolen, J.S.6
-
68
-
-
0033145354
-
MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis
-
Kotlyarov A, Neininger A, Schubert C, Eckert R, Birchmeier C, Volk HD, et al. MAPKAP kinase 2 is essential for LPS-induced TNF-alpha biosynthesis. Nat Cell Biol 1999;1:94-7.
-
(1999)
Nat Cell Biol
, vol.1
, pp. 94-97
-
-
Kotlyarov, A.1
Neininger, A.2
Schubert, C.3
Eckert, R.4
Birchmeier, C.5
Volk, H.D.6
-
69
-
-
33746214777
-
MAPKAP kinase 2-deficient mice are resistant to collagen-induced arthritis
-
Hegen M, Gaestel M, Nickerson-Nutter CL, Lin LL, Telliez JB. MAPKAP kinase 2-deficient mice are resistant to collagen-induced arthritis. J Immunol 2006;177:1913-7.
-
(2006)
J Immunol
, vol.177
, pp. 1913-1917
-
-
Hegen, M.1
Gaestel, M.2
Nickerson-Nutter, C.L.3
Lin, L.L.4
Telliez, J.B.5
-
70
-
-
0038131975
-
Therapeutic strategies for rheumatoid arthritis
-
Smolen JS, Steiner G. Therapeutic strategies for rheumatoid arthritis. Nat Rev Drug Discov 2003;2:473-88.
-
(2003)
Nat Rev Drug Discov
, vol.2
, pp. 473-488
-
-
Smolen, J.S.1
Steiner, G.2
-
71
-
-
46849085824
-
a selective inhibitor of mitogen-activated protein kinase, in rat adjuvant arthritis
-
Badger AM, Griswold DE, Kapadia R, Blake S, Swift BA, Hoffmann SJ, et al. a selective inhibitor of mitogen-activated protein kinase, in rat adjuvant arthritis. Arthritis Rheum 2000;43:75-83.
-
(2000)
Arthritis Rheum
, vol.43
, pp. 75-83
-
-
Badger, A.M.1
Griswold, D.E.2
Kapadia, R.3
Blake, S.4
Swift, B.A.5
Hoffmann, S.J.6
-
72
-
-
0141788311
-
Prevention of the onset and progression of collagen-induced arthritis in rats by the potent p38 mitogen-activated protein kinase inhibitor FR167653
-
Nishikawa M, Myoui A, Tomita T, Takahi K, Nampei A, Yishikawa H. Prevention of the onset and progression of collagen-induced arthritis in rats by the potent p38 mitogen-activated protein kinase inhibitor FR167653. Arthritis Rheum 2003;48:2670-81.
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2670-2681
-
-
Nishikawa, M.1
Myoui, A.2
Tomita, T.3
Takahi, K.4
Nampei, A.5
Yishikawa, H.6
-
73
-
-
0032745423
-
RWJ 67657, a potent, orally active inhibitor of p38 mitogen-activated protein kinase
-
Wadsworth SA, Cavender DE, Beers SA, Lalan P, Schafer PH, Malloy EA, et al. RWJ 67657, a potent, orally active inhibitor of p38 mitogen-activated protein kinase. J Pharmacol Exp Ther 1999;291:680-7.
-
(1999)
J Pharmacol Exp Ther
, vol.291
, pp. 680-687
-
-
Wadsworth, S.A.1
Cavender, D.E.2
Beers, S.A.3
Lalan, P.4
Schafer, P.H.5
Malloy, E.A.6
-
74
-
-
5644285350
-
Characterization of pristane-induced arthritis, a murine model of chronic disease: Response to antirheumatic agents, expression of joint cytokines, and immunopathology
-
Patten C, Bush K, Rioja I, Morgan R, Wooley P, Trill J, et al. Characterization of pristane-induced arthritis, a murine model of chronic disease: response to antirheumatic agents, expression of joint cytokines, and immunopathology. Arthritis Rheum 2004;50:3334-45.
-
(2004)
Arthritis Rheum
, vol.50
, pp. 3334-3345
-
-
Patten, C.1
Bush, K.2
Rioja, I.3
Morgan, R.4
Wooley, P.5
Trill, J.6
-
75
-
-
33745248460
-
A selective p38 alpha mitogen-activated protein kinase inhibitor reverses cartilage and bone destruction in mice with collagen-induced arthritis
-
Medicherla S, Ma JY, Mangadu R, Jiang Y, Zhao JJ, Almirez R, et al. A selective p38 alpha mitogen-activated protein kinase inhibitor reverses cartilage and bone destruction in mice with collagen-induced arthritis. J Pharmacol Exp Ther 2006;318:132-41.
-
(2006)
J Pharmacol Exp Ther
, vol.318
, pp. 132-141
-
-
Medicherla, S.1
Ma, J.Y.2
Mangadu, R.3
Jiang, Y.4
Zhao, J.J.5
Almirez, R.6
-
76
-
-
2942560875
-
Novel p38 inhibitors with potent oral efficacy in several models of rheumatoid arthritis
-
Revesz L, Blum E, Di Padova FE, Buhl T, Feifel R, Gram H, et al. Novel p38 inhibitors with potent oral efficacy in several models of rheumatoid arthritis. Bioorg Med Chem Lett 2004;14:3595-9.
-
(2004)
Bioorg Med Chem Lett
, vol.14
, pp. 3595-3599
-
-
Revesz, L.1
Blum, E.2
Di Padova, F.E.3
Buhl, T.4
Feifel, R.5
Gram, H.6
-
77
-
-
0031015043
-
Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases
-
Juo P, Kuo CJ, Reynolds SE, Konz RF, Raingeaud J, Davis RJ, et al. Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases. Mol Cell Biol 1997;17:24-35.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 24-35
-
-
Juo, P.1
Kuo, C.J.2
Reynolds, S.E.3
Konz, R.F.4
Raingeaud, J.5
Davis, R.J.6
-
78
-
-
0032910884
-
Evaluation of the role of mitogen-activated protein kinases in the expression of inducible nitric oxide synthase by IFN-gamma and TNF-alpha in mouse macrophages
-
Chan ED, Winston BW, Uh ST, Wynes MW, Rose DM, Riches DW. Evaluation of the role of mitogen-activated protein kinases in the expression of inducible nitric oxide synthase by IFN-gamma and TNF-alpha in mouse macrophages. J Immunol 1999;162:415-22.
-
(1999)
J Immunol
, vol.162
, pp. 415-422
-
-
Chan, E.D.1
Winston, B.W.2
Uh, S.T.3
Wynes, M.W.4
Rose, D.M.5
Riches, D.W.6
-
79
-
-
0032519736
-
p38 mitogen-activated protein kinase activation is required for human neutrophil function triggered by TNF-alpha or FMLP stimulation
-
Zu YL, Qi J, Gilchrist A, Fernandez GA, Vazquez-Abad D, Kreutzer DL, et al. p38 mitogen-activated protein kinase activation is required for human neutrophil function triggered by TNF-alpha or FMLP stimulation. J Immunol 1998;160:1982-9.
-
(1998)
J Immunol
, vol.160
, pp. 1982-1989
-
-
Zu, Y.L.1
Qi, J.2
Gilchrist, A.3
Fernandez, G.A.4
Vazquez-Abad, D.5
Kreutzer, D.L.6
-
80
-
-
0035080457
-
Invasiveness of synovial fibroblasts is regulated by p53 in the SCID mouse in vivo model of cartilage invasion
-
Pap T, Aupperle KR, Gay S, Firestein GS, Gay RE. Invasiveness of synovial fibroblasts is regulated by p53 in the SCID mouse in vivo model of cartilage invasion. Arthritis Rheum 2001;44:676-81.
-
(2001)
Arthritis Rheum
, vol.44
, pp. 676-681
-
-
Pap, T.1
Aupperle, K.R.2
Gay, S.3
Firestein, G.S.4
Gay, R.E.5
-
81
-
-
0345189496
-
The SCID mouse - a novel experimental model for gene therapy in human rheumatoid arthritis
-
Muller-Ladner U, Gay S. The SCID mouse - a novel experimental model for gene therapy in human rheumatoid arthritis. Drugs Today 1999;3:379-88.
-
(1999)
Drugs Today
, vol.3
, pp. 379-388
-
-
Muller-Ladner, U.1
Gay, S.2
-
82
-
-
0037811204
-
Induction of matrix metalloproteinase-13 gene expression by TNF-alpha is mediated by MAP kinases, AP-1, and NF-kappaB transcription factors in articular chondrocytes
-
Liacini A, Sylvester J, Li WQ, Huang W, Dehnade F, Ahmad M, et al. Induction of matrix metalloproteinase-13 gene expression by TNF-alpha is mediated by MAP kinases, AP-1, and NF-kappaB transcription factors in articular chondrocytes. Exp Cell Res 2003;288:208-17.
-
(2003)
Exp Cell Res
, vol.288
, pp. 208-217
-
-
Liacini, A.1
Sylvester, J.2
Li, W.Q.3
Huang, W.4
Dehnade, F.5
Ahmad, M.6
-
83
-
-
0033987112
-
The role of p38 mitogen-activated protein kinase in IL-6 and IL-8 production from the TNF-alpha- or IL-1beta-stimulated rheumatoid synovial fibroblasts
-
Suzuki M, Tetsuka T, Yoshida S, Watanabe N, Kobayashi M, Matsui N, et al. The role of p38 mitogen-activated protein kinase in IL-6 and IL-8 production from the TNF-alpha- or IL-1beta-stimulated rheumatoid synovial fibroblasts. FEBS Lett 2000;465:23-7.
-
(2000)
FEBS Lett
, vol.465
, pp. 23-27
-
-
Suzuki, M.1
Tetsuka, T.2
Yoshida, S.3
Watanabe, N.4
Kobayashi, M.5
Matsui, N.6
-
84
-
-
0036853902
-
Osteoclasts are essential for TNF-alpha-mediated joint destruction
-
Redlich K, Hayer S, Ricci R, David JP, Tohidast-Akrad M, Kollias G, et al. Osteoclasts are essential for TNF-alpha-mediated joint destruction. J Clin Invest 2002;110:1419-27.
-
(2002)
J Clin Invest
, vol.110
, pp. 1419-1427
-
-
Redlich, K.1
Hayer, S.2
Ricci, R.3
David, J.P.4
Tohidast-Akrad, M.5
Kollias, G.6
-
85
-
-
0031894140
-
Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritis
-
Gravallese EM, Harada Y, Wang JT, Gorn AH, Thornhill TS, Goldring SR. Identification of cell types responsible for bone resorption in rheumatoid arthritis and juvenile rheumatoid arthritis. Am J Pathol 1998;152:943-51.
-
(1998)
Am J Pathol
, vol.152
, pp. 943-951
-
-
Gravallese, E.M.1
Harada, Y.2
Wang, J.T.3
Gorn, A.H.4
Thornhill, T.S.5
Goldring, S.R.6
-
86
-
-
33749009030
-
Mechanisms of disease: The link between RANKL and arthritic bone disease
-
Schett G, Hayer S, Zwerina J, Redlich K, Smolen JS. Mechanisms of disease: the link between RANKL and arthritic bone disease. Nat Clin Pract Rheumatol 2005;1:47-54.
-
(2005)
Nat Clin Pract Rheumatol
, vol.1
, pp. 47-54
-
-
Schett, G.1
Hayer, S.2
Zwerina, J.3
Redlich, K.4
Smolen, J.S.5
-
87
-
-
0036321005
-
p38 MAPK-mediated signals are required for inducing osteoclast differentiation but not for osteoclast function
-
Li X, Udagawa N, Itoh K, Suda K, Murase Y, Nishihara T, et al. p38 MAPK-mediated signals are required for inducing osteoclast differentiation but not for osteoclast function. Endocrinology 2002;143:3105-13.
-
(2002)
Endocrinology
, vol.143
, pp. 3105-3113
-
-
Li, X.1
Udagawa, N.2
Itoh, K.3
Suda, K.4
Murase, Y.5
Nishihara, T.6
-
88
-
-
0034548760
-
Activation of p38 mitogen-activated protein kinase is crucial in osteoclastogenesis induced by tumor necrosis factor
-
Matsumoto M, Sudo T, Maruyama M, Osada H, Tsujimoto M. Activation of p38 mitogen-activated protein kinase is crucial in osteoclastogenesis induced by tumor necrosis factor. FEBS Lett 2000;486:23-8.
-
(2000)
FEBS Lett
, vol.486
, pp. 23-28
-
-
Matsumoto, M.1
Sudo, T.2
Maruyama, M.3
Osada, H.4
Tsujimoto, M.5
-
89
-
-
0030734010
-
p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells
-
Rosseau S, Houle F, Landry J, Huot J. p38 MAP kinase activation by vascular endothelial growth factor mediates actin reorganization and cell migration in human endothelial cells. Oncogene 1997;15:2169-77.
-
(1997)
Oncogene
, vol.15
, pp. 2169-2177
-
-
Rosseau, S.1
Houle, F.2
Landry, J.3
Huot, J.4
-
90
-
-
0031018424
-
Tumor necrosis factor alpha-induced E-selectin expression is activated by the nuclear factor-kappaB and c-JUN N-terminal kinase/p38 mitogen-activated protein kinase pathways
-
Read MA, Whitley MZ, Gupta S, Pierce JW, Best J, Davies RJ, ef al. Tumor necrosis factor alpha-induced E-selectin expression is activated by the nuclear factor-kappaB and c-JUN N-terminal kinase/p38 mitogen-activated protein kinase pathways. J Biol Chem 1997;272:2753-61
-
(1997)
J Biol Chem
, vol.272
, pp. 2753-2761
-
-
Read, M.A.1
Whitley, M.Z.2
Gupta, S.3
Pierce, J.W.4
Best, J.5
Davies, R.J.6
ef al7
-
91
-
-
0031550222
-
p38 mitogen activated protein kinase regulates endothelial VCAM-1 expression at the post-transcriptional level
-
Pietersma A, Tilly BC, Gaestel M, de Jong N, Lee JC, Koster JF, et al. p38 mitogen activated protein kinase regulates endothelial VCAM-1 expression at the post-transcriptional level. Biochem Biophys Res Commun 1997;230:44-8.
-
(1997)
Biochem Biophys Res Commun
, vol.230
, pp. 44-48
-
-
Pietersma, A.1
Tilly, B.C.2
Gaestel, M.3
de Jong, N.4
Lee, J.C.5
Koster, J.F.6
-
92
-
-
0032936517
-
The MKK6/ p38 stress kinase cascade is critical for tumor necrosis factor-alpha-induced expression of monocyte-chemoattractant protein-1 in endothelial cells
-
Goebeler M, Kilian K, Gillitzer R, Kunz M, Yoshimura T, Brocker EB, et al. The MKK6/ p38 stress kinase cascade is critical for tumor necrosis factor-alpha-induced expression of monocyte-chemoattractant protein-1 in endothelial cells. Blood 1999;93:857-65.
-
(1999)
Blood
, vol.93
, pp. 857-865
-
-
Goebeler, M.1
Kilian, K.2
Gillitzer, R.3
Kunz, M.4
Yoshimura, T.5
Brocker, E.B.6
|