-
1
-
-
0030898417
-
Mitogen-activated protein kinase pathways
-
Robinson MJ, Cobb MH: Mitogen-activated protein kinase pathways. Curr Opin Cell Biol 1997, 9:180-186
-
(1997)
Curr Opin Cell Biol
, vol.9
, pp. 180-186
-
-
Robinson, M.J.1
Cobb, M.H.2
-
2
-
-
0035066383
-
Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation
-
Kyriakis JM, Avruch J: Mammalian mitogen-activated protein kinase signal transduction pathways activated by stress and inflammation. Physiol Rev 2001, 81:807-869
-
(2001)
Physiol Rev
, vol.81
, pp. 807-869
-
-
Kyriakis, J.M.1
Avruch, J.2
-
3
-
-
0032544234
-
Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase
-
Miyazawa K, Mori A, Miyata H, Akahane M, Ajisawa Y, Okudaira H: Regulation of interleukin-1beta-induced interleukin-6 gene expression in human fibroblast-like synoviocytes by p38 mitogen-activated protein kinase. J Biol Chem 1998, 273:24832-24838
-
(1998)
J Biol Chem
, vol.273
, pp. 24832-24838
-
-
Miyazawa, K.1
Mori, A.2
Miyata, H.3
Akahane, M.4
Ajisawa, Y.5
Okudaira, H.6
-
4
-
-
0033987112
-
The role of p38 mitogen-activated protein kinase in IL-6 and IL-8 production from the TNF-alpha- or IL-1beta-stimulated rheumatoid synovial fibroblasts
-
Suzuki M, Tetsuka T, Yoshida S, Watanabe N, Kobayashi M, Matsui N, Okamoto T: The role of p38 mitogen-activated protein kinase in IL-6 and IL-8 production from the TNF-alpha- or IL-1beta-stimulated rheumatoid synovial fibroblasts. FEBS Lett 2000, 465:23-27
-
(2000)
FEBS Lett
, vol.465
, pp. 23-27
-
-
Suzuki, M.1
Tetsuka, T.2
Yoshida, S.3
Watanabe, N.4
Kobayashi, M.5
Matsui, N.6
Okamoto, T.7
-
5
-
-
0033758633
-
Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis
-
Schett G, Tohidast-Akrad M, Smolen JS, Schmid BJ, Steiner CW, Bitzan P, Zenz P, Redlich K, Xu Q, Steiner G: Activation, differential localization, and regulation of the stress-activated protein kinases, extracellular signal-regulated kinase, c-JUN N-terminal kinase, and p38 mitogen-activated protein kinase, in synovial tissue and cells in rheumatoid arthritis. Arthritis Rheum 2000, 43:2501-2512
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2501-2512
-
-
Schett, G.1
Tohidast-Akrad, M.2
Smolen, J.S.3
Schmid, B.J.4
Steiner, C.W.5
Bitzan, P.6
Zenz, P.7
Redlich, K.8
Xu, Q.9
Steiner, G.10
-
6
-
-
0035086636
-
The discovery of RPR 200765A, a p38 MAP kinase inhibitor displaying a good oral anti-arthritic efficacy
-
McLay LM, Halley F, Souness JE, McKenna J, Benning V, Birrell M, Burton B, Belvisi M, Collis A, Constan A, Foster M, Hele D, Jayyosi Z, Kelley M, Maslen C, Miller G, Ouldelhkim MC, Page K, Phipps S, Pollock K, Porter B, Ratcliffe AJ, Redford EJ, Webber S, Slater B, Thybaud V, Wilsher N: The discovery of RPR 200765A, a p38 MAP kinase inhibitor displaying a good oral anti-arthritic efficacy. Bioorg Med Chem 2001, 9:537-554
-
(2001)
Bioorg Med Chem
, vol.9
, pp. 537-554
-
-
McLay, L.M.1
Halley, F.2
Souness, J.E.3
McKenna, J.4
Benning, V.5
Birrell, M.6
Burton, B.7
Belvisi, M.8
Collis, A.9
Constan, A.10
Foster, M.11
Hele, D.12
Jayyosi, Z.13
Kelley, M.14
Maslen, C.15
Miller, G.16
Ouldelhkim, M.C.17
Page, K.18
Phipps, S.19
Pollock, K.20
Porter, B.21
Ratcliffe, A.J.22
Redford, E.J.23
Webber, S.24
Slater, B.25
Thybaud, V.26
Wilsher, N.27
more..
-
7
-
-
15844431960
-
A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3
-
Moriguchi T, Kuroyanagi N, Yamaguchi K, Gotoh Y, Irie K, Kano T, Shirakabe K, Muro Y, Shibuya H, Matsumoto K, Nishida E, Hagiwara M: A novel kinase cascade mediated by mitogen-activated protein kinase kinase 6 and MKK3. J Biol Chem 1996, 271:13675-13679
-
(1996)
J Biol Chem
, vol.271
, pp. 13675-13679
-
-
Moriguchi, T.1
Kuroyanagi, N.2
Yamaguchi, K.3
Gotoh, Y.4
Irie, K.5
Kano, T.6
Shirakabe, K.7
Muro, Y.8
Shibuya, H.9
Matsumoto, K.10
Nishida, E.11
Hagiwara, M.12
-
8
-
-
0030044182
-
Characterization of the structure and function of a novel MAP kinase kinase (MKK6)
-
Han J, Lee JD, Jiang Y, Li Z, Feng L, Ulevitch RJ: Characterization of the structure and function of a novel MAP kinase kinase (MKK6). J Biol Chem 1996, 271:2886-2891
-
(1996)
J Biol Chem
, vol.271
, pp. 2886-2891
-
-
Han, J.1
Lee, J.D.2
Jiang, Y.3
Li, Z.4
Feng, L.5
Ulevitch, R.J.6
-
9
-
-
0030006618
-
Cloning and characterization of MEK6, a novel member of the mitogen-activated protein kinase kinase cascade
-
Stein B, Brady H, Yang MX, Young DB, Barbosa MS: Cloning and characterization of MEK6, a novel member of the mitogen-activated protein kinase kinase cascade. J Biol Chem 1996, 271:11427-11433
-
(1996)
J Biol Chem
, vol.271
, pp. 11427-11433
-
-
Stein, B.1
Brady, H.2
Yang, M.X.3
Young, D.B.4
Barbosa, M.S.5
-
10
-
-
0033118982
-
Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice
-
Lu HT, Yang DD, Wysk M, Gatti E, Mellman I, Davis RJ, Flavell RA: Defective IL-12 production in mitogen-activated protein (MAP) kinase kinase 3 (Mkk3)-deficient mice. EMBO J 1999, 18:1845-1857
-
(1999)
EMBO J
, vol.18
, pp. 1845-1857
-
-
Lu, H.T.1
Yang, D.D.2
Wysk, M.3
Gatti, E.4
Mellman, I.5
Davis, R.J.6
Flavell, R.A.7
-
11
-
-
0036687249
-
Differential involvement of p38 mitogen-activated protein kinase kinases MKK3 and MKK6 in T-cell apoptosis
-
Tanaka N, Kamanaka M, Enslen H, Dong C, Wysk M, Davis RJ, Flavell RA: Differential involvement of p38 mitogen-activated protein kinase kinases MKK3 and MKK6 in T-cell apoptosis. EMBO Rep 2002, 3:785-791
-
(2002)
EMBO Rep
, vol.3
, pp. 785-791
-
-
Tanaka, N.1
Kamanaka, M.2
Enslen, H.3
Dong, C.4
Wysk, M.5
Davis, R.J.6
Flavell, R.A.7
-
12
-
-
0031015043
-
Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases
-
Juo P, Kuo CJ, Reynolds SE, Konz RF, Raingeaud J, Davis RJ, Biemann HP, Blenis J: Fas activation of the p38 mitogen-activated protein kinase signalling pathway requires ICE/CED-3 family proteases. Mol Cell Biol 1997, 17:24-35
-
(1997)
Mol Cell Biol
, vol.17
, pp. 24-35
-
-
Juo, P.1
Kuo, C.J.2
Reynolds, S.E.3
Konz, R.F.4
Raingeaud, J.5
Davis, R.J.6
Biemann, H.P.7
Blenis, J.8
-
13
-
-
2242463086
-
Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells
-
Han Q, Leng J, Bian D, Mahanivong C, Carpenter KA, Pan ZK, Han J, Huang S: Rac1-MKK3-p38-MAPKAPK2 pathway promotes urokinase plasminogen activator mRNA stability in invasive breast cancer cells. J Biol Chem 2002, 277:48379-48385
-
(2002)
J Biol Chem
, vol.277
, pp. 48379-48385
-
-
Han, Q.1
Leng, J.2
Bian, D.3
Mahanivong, C.4
Carpenter, K.A.5
Pan, Z.K.6
Han, J.7
Huang, S.8
-
14
-
-
0031044561
-
MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: Upstream regulators of the c-Jun amino-terminal kinases?
-
Fanger GR, Gerwins P, Widmann C, Jarpe MB, Johnson GL: MEKKs, GCKs, MLKs, PAKs, TAKs, and tpls: upstream regulators of the c-Jun amino-terminal kinases? Curr Opin Genet Dev 1997, 7:67-74
-
(1997)
Curr Opin Genet Dev
, vol.7
, pp. 67-74
-
-
Fanger, G.R.1
Gerwins, P.2
Widmann, C.3
Jarpe, M.B.4
Johnson, G.L.5
-
15
-
-
0031916832
-
Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6
-
Enslen H, Raingeaud J, Davis RJ: Selective activation of p38 mitogen-activated protein (MAP) kinase isoforms by the MAP kinase kinases MKK3 and MKK6. J Biol Chem 1998, 273:1741-1748
-
(1998)
J Biol Chem
, vol.273
, pp. 1741-1748
-
-
Enslen, H.1
Raingeaud, J.2
Davis, R.J.3
-
16
-
-
10244241798
-
Purification and identification of a major activator for p38 from osmotically shocked cells. Activation of mitogen-activated protein kinase kinase 6 by osmotic shock, tumor necrosis factor-alpha, and H2O2
-
Moriguchi T, Toyoshima F, Gotoh Y, Iwamatsu A, Irie K, Mori E, Kuroyanagi N, Hagiwara M, Matsumoto K, Nishida E: Purification and identification of a major activator for p38 from osmotically shocked cells. Activation of mitogen-activated protein kinase kinase 6 by osmotic shock, tumor necrosis factor-alpha, and H2O2. J Biol Chem 1996, 271:26981-26988
-
(1996)
J Biol Chem
, vol.271
, pp. 26981-26988
-
-
Moriguchi, T.1
Toyoshima, F.2
Gotoh, Y.3
Iwamatsu, A.4
Irie, K.5
Mori, E.6
Kuroyanagi, N.7
Hagiwara, M.8
Matsumoto, K.9
Nishida, E.10
-
17
-
-
0033616588
-
Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression
-
Wysk M, Yang DD, Lu HT, Flavell RA, Davis RJ: Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for tumor necrosis factor-induced cytokine expression. Proc Natl Acad Sci USA 1999, 96:3763-3768
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 3763-3768
-
-
Wysk, M.1
Yang, D.D.2
Lu, H.T.3
Flavell, R.A.4
Davis, R.J.5
-
18
-
-
0025847243
-
Cytokines in chronic inflammatory arthritis. VI. Analysis of the synovial cells involved in granulocyte-macrophage colony-stimulating factor production and gene expression in rheumatoid arthritis and its regulation by IL-1 and tumor necrosis factor-alpha
-
Alvaro-Gracia JM, Zvaifler NJ, Brown CB, Kaushansky K, Firestein GS: Cytokines in chronic inflammatory arthritis. VI. Analysis of the synovial cells involved in granulocyte-macrophage colony-stimulating factor production and gene expression in rheumatoid arthritis and its regulation by IL-1 and tumor necrosis factor-alpha. J Immunol 1991, 146:3365-3371
-
(1991)
J Immunol
, vol.146
, pp. 3365-3371
-
-
Alvaro-Gracia, J.M.1
Zvaifler, N.J.2
Brown, C.B.3
Kaushansky, K.4
Firestein, G.S.5
-
19
-
-
0023945481
-
The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis
-
Arnett FC, Edworthy SM, Bloch DA, McShane DJ, Fries JF, Cooper NS, Healey LA, Kaplan SR, Liang MH, Luthra HS, Medsger Jr TA, Mitchell DM, Neustadt OH, Pinals RS, Schaller JG, Sharp JT, Wilder RL, Hunder GG: The American Rheumatism Association 1987 revised criteria for the classification of rheumatoid arthritis. Arthritis Rheum 1988, 31:315-324
-
(1988)
Arthritis Rheum
, vol.31
, pp. 315-324
-
-
Arnett, F.C.1
Edworthy, S.M.2
Bloch, D.A.3
McShane, D.J.4
Fries, J.F.5
Cooper, N.S.6
Healey, L.A.7
Kaplan, S.R.8
Liang, M.H.9
Luthra, H.S.10
Medsger Jr., T.A.11
Mitchell, D.M.12
Neustadt, O.H.13
Pinals, R.S.14
Schaller, J.G.15
Sharp, J.T.16
Wilder, R.L.17
Hunder, G.G.18
-
20
-
-
0032963771
-
Expression of the activation antigen CD97 and its ligand CD55 in rheumatoid synovial tissue
-
Hamann J, Wishaupt JO, van Lier RA, Smeets TJ, Breedveld FC, Tak PP: Expression of the activation antigen CD97 and its ligand CD55 in rheumatoid synovial tissue. Arthritis Rheum 1999, 42:650-658
-
(1999)
Arthritis Rheum
, vol.42
, pp. 650-658
-
-
Hamann, J.1
Wishaupt, J.O.2
Van Lier, R.A.3
Smeets, T.J.4
Breedveld, F.C.5
Tak, P.P.6
-
21
-
-
0028044630
-
Expression and functional significance of alternatively spliced CS1 fibronectin in rheumatoid arthritis microvasculature
-
Elices MJ, Tsai V, Strahl D, Goel AS, Tollefson V, Arrhenius T, Wayner EA, Gaeta FC, Fikes JD, Firestein GS: Expression and functional significance of alternatively spliced CS1 fibronectin in rheumatoid arthritis microvasculature. J Clin Invest 1994, 93:405-416
-
(1994)
J Clin Invest
, vol.93
, pp. 405-416
-
-
Elices, M.J.1
Tsai, V.2
Strahl, D.3
Goel, A.S.4
Tollefson, V.5
Arrhenius, T.6
Wayner, E.A.7
Gaeta, F.C.8
Fikes, J.D.9
Firestein, G.S.10
-
22
-
-
0141676444
-
Expression of the MAPK kinases MKK-4 and MKK-7 in rheumatoid arthritis and their role as key regulators of JNK
-
Sundarrajan M, Boyle DL, Chabaud-Riou M, Hammaker D, Firestein GS: Expression of the MAPK kinases MKK-4 and MKK-7 in rheumatoid arthritis and their role as key regulators of JNK. Arthritis Rheum 2003, 48:2450-2460
-
(2003)
Arthritis Rheum
, vol.48
, pp. 2450-2460
-
-
Sundarrajan, M.1
Boyle, D.L.2
Chabaud-Riou, M.3
Hammaker, D.4
Firestein, G.S.5
-
23
-
-
0025304539
-
Rheumatoid arthritis. Pathophysiology and implications for therapy
-
Harris Jr ED: Rheumatoid arthritis. Pathophysiology and implications for therapy. N Engl J Med 1990, 322:1277-1289
-
(1990)
N Engl J Med
, vol.322
, pp. 1277-1289
-
-
Harris Jr., E.D.1
-
24
-
-
0032931433
-
Signal transduction and transcription factors in rheumatic disease
-
Firestein GS, Manning AM: Signal transduction and transcription factors in rheumatic disease. Arthritis Rheum 1999, 42:609-621
-
(1999)
Arthritis Rheum
, vol.42
, pp. 609-621
-
-
Firestein, G.S.1
Manning, A.M.2
-
25
-
-
0038011833
-
Evolving concepts of rheumatoid arthritis
-
Firestein GS: Evolving concepts of rheumatoid arthritis. Nature 2003, 423:356-361
-
(2003)
Nature
, vol.423
, pp. 356-361
-
-
Firestein, G.S.1
-
26
-
-
0035040946
-
IL-1-and TNF-induced bone resorption is mediated by p38 mitogen activated protein kinase
-
Kumar S, Votta BJ, Rieman DJ, Badger AM, Gowen M, Lee JC: IL-1-and TNF-induced bone resorption is mediated by p38 mitogen activated protein kinase. J Cell Physiol 2001, 187:294-303
-
(2001)
J Cell Physiol
, vol.187
, pp. 294-303
-
-
Kumar, S.1
Votta, B.J.2
Rieman, D.J.3
Badger, A.M.4
Gowen, M.5
Lee, J.C.6
-
27
-
-
0028605318
-
A protein kinase involved in the regulation of inflammatory cytokine biosynthesis
-
Lee JC, Laydon JT, McDonnell PC, Gallagher TF, Kumar S, Green D, McNulty D, Blumenthal MJ, Heys JR, Landvatter SW, Strickler D, McLaughlin MH, Siemens IR, Fisher SM, Livi GP, White JR, Adams JL, Young PR: A protein kinase involved in the regulation of inflammatory cytokine biosynthesis. Nature 1994, 372:739-746
-
(1994)
Nature
, vol.372
, pp. 739-746
-
-
Lee, J.C.1
Laydon, J.T.2
McDonnell, P.C.3
Gallagher, T.F.4
Kumar, S.5
Green, D.6
McNulty, D.7
Blumenthal, M.J.8
Heys, J.R.9
Landvatter, S.W.10
Strickler, D.11
McLaughlin, M.H.12
Siemens, I.R.13
Fisher, S.M.14
Livi, G.P.15
White, J.R.16
Adams, J.L.17
Young, P.R.18
-
28
-
-
0028983172
-
Inhibition of interleukin-1 beta production by SKF86002: Evidence of two sites of in vitro activity and of a time and system dependence
-
Perregaux DG, Dean D, Cronan M, Connelly P, Gabel CA: Inhibition of interleukin-1 beta production by SKF86002: evidence of two sites of in vitro activity and of a time and system dependence. Mol Pharmacol 1995, 48:433-442
-
(1995)
Mol Pharmacol
, vol.48
, pp. 433-442
-
-
Perregaux, D.G.1
Dean, D.2
Cronan, M.3
Connelly, P.4
Gabel, C.A.5
-
29
-
-
0028935270
-
Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine
-
Raingeaud J, Gupta S, Rogers JS, Dickens M, Han J, Ulevitch RJ, Davis RJ: Pro-inflammatory cytokines and environmental stress cause p38 mitogen-activated protein kinase activation by dual phosphorylation on tyrosine and threonine. J Biol Chem 1995, 270:7420-7426
-
(1995)
J Biol Chem
, vol.270
, pp. 7420-7426
-
-
Raingeaud, J.1
Gupta, S.2
Rogers, J.S.3
Dickens, M.4
Han, J.5
Ulevitch, R.J.6
Davis, R.J.7
-
30
-
-
0031803059
-
SB 203580 inhibits p38 mitogen-activated protein kinase, nitric oxide production, and inducible nitric oxide synthase in bovine cartilage-derived chondrocytes
-
Badger AM, Cook MN, Lark MW, Newman-Tarr TM, Swift BA, Nelson AH, Barone FC, Kumar S: SB 203580 inhibits p38 mitogen-activated protein kinase, nitric oxide production, and inducible nitric oxide synthase in bovine cartilage-derived chondrocytes. J Immunol 1998, 161:467-473
-
(1998)
J Immunol
, vol.161
, pp. 467-473
-
-
Badger, A.M.1
Cook, M.N.2
Lark, M.W.3
Newman-Tarr, T.M.4
Swift, B.A.5
Nelson, A.H.6
Barone, F.C.7
Kumar, S.8
-
31
-
-
0027217131
-
Pyridinyl imidazoles inhibit IL-1 and TNF production at the protein level
-
Young P, McDonnell P, Dunnington D, Hand A, Laydon J, Lee J: Pyridinyl imidazoles inhibit IL-1 and TNF production at the protein level. Agents Actions 1993, 39:C67-C69
-
(1993)
Agents Actions
, vol.39
-
-
Young, P.1
McDonnell, P.2
Dunnington, D.3
Hand, A.4
Laydon, J.5
Lee, J.6
-
32
-
-
0028935974
-
Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms
-
Derijard B, Raingeaud J, Barrett T, Wu IH, Han J, Ulevitch RJ, Davis RJ: Independent human MAP-kinase signal transduction pathways defined by MEK and MKK isoforms. Science 1995, 267:682-685
-
(1995)
Science
, vol.267
, pp. 682-685
-
-
Derijard, B.1
Raingeaud, J.2
Barrett, T.3
Wu, I.H.4
Han, J.5
Ulevitch, R.J.6
Davis, R.J.7
-
33
-
-
0030051528
-
MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway
-
Raingeaud J, Whitmarsh AJ, Barrett T, Derijard B, Davis RJ: MKK3- and MKK6-regulated gene expression is mediated by the p38 mitogen-activated protein kinase signal transduction pathway. Mol Cell Biol 1996, 16:1247-1255
-
(1996)
Mol Cell Biol
, vol.16
, pp. 1247-1255
-
-
Raingeaud, J.1
Whitmarsh, A.J.2
Barrett, T.3
Derijard, B.4
Davis, R.J.5
-
34
-
-
0033598783
-
c-Abl-induced apoplosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation
-
Cong F, Goff SP: c-Abl-induced apoplosis, but not cell cycle arrest, requires mitogen-activated protein kinase kinase 6 activation. Proc Natl Acad Sci USA 1999, 96:13819-13824
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 13819-13824
-
-
Cong, F.1
Goff, S.P.2
-
35
-
-
0028943245
-
Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2
-
Lin A, Minden A, Martinetto H, Claret FX, Lange-Carter C, Mercurio F, Johnson GL, Karin M: Identification of a dual specificity kinase that activates the Jun kinases and p38-Mpk2. Science 1995, 268:286-290
-
(1995)
Science
, vol.268
, pp. 286-290
-
-
Lin, A.1
Minden, A.2
Martinetto, H.3
Claret, F.X.4
Lange-Carter, C.5
Mercurio, F.6
Johnson, G.L.7
Karin, M.8
-
36
-
-
0034541591
-
Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: Association with genomic DNA hypomethylation and influence on gene expression
-
Neidhart M, Rethage J, Kuchen S, Kunzler P, Crowl RM, Billingham ME, Gay RE, Gay S: Retrotransposable L1 elements expressed in rheumatoid arthritis synovial tissue: association with genomic DNA hypomethylation and influence on gene expression. Arthritis Rheum 2000, 43:2634-2647
-
(2000)
Arthritis Rheum
, vol.43
, pp. 2634-2647
-
-
Neidhart, M.1
Rethage, J.2
Kuchen, S.3
Kunzler, P.4
Crowl, R.M.5
Billingham, M.E.6
Gay, R.E.7
Gay, S.8
-
37
-
-
0034121690
-
Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis
-
Badger AM, Griswold DE, Kapadia R, Blake S, Swift BA, Hoffman SJ, Stroup GB, Webb E, Rieman DJ, Gowen M, Boehm JC, Adams JL, Lee JC: Disease-modifying activity of SB 242235, a selective inhibitor of p38 mitogen-activated protein kinase, in rat adjuvant-induced arthritis. Arthritis Rheum 2000, 43:175-183
-
(2000)
Arthritis Rheum
, vol.43
, pp. 175-183
-
-
Badger, A.M.1
Griswold, D.E.2
Kapadia, R.3
Blake, S.4
Swift, B.A.5
Hoffman, S.J.6
Stroup, G.B.7
Webb, E.8
Rieman, D.J.9
Gowen, M.10
Boehm, J.C.11
Adams, J.L.12
Lee, J.C.13
-
38
-
-
0030927106
-
Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases
-
Goedert M, Cuenda A, Craxton M, Jakes R, Cohen P: Activation of the novel stress-activated protein kinase SAPK4 by cytokines and cellular stresses is mediated by SKK3 (MKK6); comparison of its substrate specificity with that of other SAP kinases. EMBO J 1997, 16:3563-3571
-
(1997)
EMBO J
, vol.16
, pp. 3563-3571
-
-
Goedert, M.1
Cuenda, A.2
Craxton, M.3
Jakes, R.4
Cohen, P.5
-
39
-
-
0038260539
-
Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for activation of p38alpha and p38delta MAPK isoforms by TGF-beta 1 in murine mesangial cells
-
Wang L, Ma R, Flavell RA, Choi ME: Requirement of mitogen-activated protein kinase kinase 3 (MKK3) for activation of p38alpha and p38delta MAPK isoforms by TGF-beta 1 in murine mesangial cells. J Biol Chem 2002, 277:47257-47262
-
(2002)
J Biol Chem
, vol.277
, pp. 47257-47262
-
-
Wang, L.1
Ma, R.2
Flavell, R.A.3
Choi, M.E.4
-
40
-
-
10544223749
-
Mammalian mitogen-activated protein kinase pathways are regulated through formation of specific kinase-activator complexes
-
Zanke BW, Rubie EA, Winnett E, Chan J, Randall S, Parsons M, Boudreau K, McInnis M, Yan M, Templeton DJ, Woodgett JR: Mammalian mitogen-activated protein kinase pathways are regulated through formation of specific kinase-activator complexes. J Biol Chem 1996, 271:29876-29881
-
(1996)
J Biol Chem
, vol.271
, pp. 29876-29881
-
-
Zanke, B.W.1
Rubie, E.A.2
Winnett, E.3
Chan, J.4
Randall, S.5
Parsons, M.6
Boudreau, K.7
McInnis, M.8
Yan, M.9
Templeton, D.J.10
Woodgett, J.R.11
-
41
-
-
0036265520
-
Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade
-
Buchsbaum RJ, Connolly BA, Feig LA: Interaction of Rac exchange factors Tiam1 and Ras-GRF1 with a scaffold for the p38 mitogen-activated protein kinase cascade. Mol Cell Biol 2002, 22:4073-4085
-
(2002)
Mol Cell Biol
, vol.22
, pp. 4073-4085
-
-
Buchsbaum, R.J.1
Connolly, B.A.2
Feig, L.A.3
-
42
-
-
0033578721
-
Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression
-
Hanafusa H, Ninomiya-Tsuji J, Masuyama N, Nishita M, Fujisawa J, Shibuya H, Matsumoto K, Nishida E: Involvement of the p38 mitogen-activated protein kinase pathway in transforming growth factor-beta-induced gene expression. J Biol Chem 1999, 274:27161-27167
-
(1999)
J Biol Chem
, vol.274
, pp. 27161-27167
-
-
Hanafusa, H.1
Ninomiya-Tsuji, J.2
Masuyama, N.3
Nishita, M.4
Fujisawa, J.5
Shibuya, H.6
Matsumoto, K.7
Nishida, E.8
-
43
-
-
0034284088
-
Importance of the MKK6/p38 pathway for interleukin-12-induced STAT4 serine phosphorylation and transcriptional activity
-
Visconti R, Gadina M, Chiariello M, Chen EH, Stancato LF, Gutkind JS, O'Shea JJ: Importance of the MKK6/p38 pathway for interleukin-12-induced STAT4 serine phosphorylation and transcriptional activity. Blood 2000, 96:1844-1852
-
(2000)
Blood
, vol.96
, pp. 1844-1852
-
-
Visconti, R.1
Gadina, M.2
Chiariello, M.3
Chen, E.H.4
Stancato, L.F.5
Gutkind, J.S.6
O'Shea, J.J.7
|