-
1
-
-
0036673665
-
Glutathione depletion enforces the mitochondrial permeability transition and causes cell death in Bcl-2 overexpressing HL60 cells
-
Armstrong J.S., Jones D.P. Glutathione depletion enforces the mitochondrial permeability transition and causes cell death in Bcl-2 overexpressing HL60 cells. FASEB Journal. 16:2002;1263-1265
-
(2002)
FASEB Journal
, vol.16
, pp. 1263-1265
-
-
Armstrong, J.S.1
Jones, D.P.2
-
2
-
-
0036024973
-
In vivo and in organello assessment of OXPHOS activities
-
Barrientos A. In vivo and in organello assessment of OXPHOS activities. Methods. 26:2002;307-316
-
(2002)
Methods
, vol.26
, pp. 307-316
-
-
Barrientos, A.1
-
3
-
-
0026701521
-
Fruit, vegetables, and cancer prevention: A review of the epidemiological evidence
-
Block G., Patterson B., Subar A. Fruit, vegetables, and cancer prevention: A review of the epidemiological evidence. Nutrition and Cancer. 1:1992;1-29
-
(1992)
Nutrition and Cancer
, vol.1
, pp. 1-29
-
-
Block, G.1
Patterson, B.2
Subar, A.3
-
4
-
-
0037213368
-
The Bcl-2 protein family: Sensors and checkpoints for life-or-death decisions
-
Borner C. The Bcl-2 protein family: Sensors and checkpoints for life-or-death decisions. Molecular Immunology. 39:2003;615-647
-
(2003)
Molecular Immunology
, vol.39
, pp. 615-647
-
-
Borner, C.1
-
5
-
-
0036478928
-
The Apaf-1 apoptosome: A large caspase-activating complex
-
Cain K., Bratton S.B., Cohen G.M. The Apaf-1 apoptosome: A large caspase-activating complex. Biochimie. 84:2002;203-214
-
(2002)
Biochimie
, vol.84
, pp. 203-214
-
-
Cain, K.1
Bratton, S.B.2
Cohen, G.M.3
-
6
-
-
0037070160
-
Involvement of the N-terminus of Bax in its intracellular localization and function
-
Cartron P.-F., Moreau C., Oliver L., Mayat E., Meflah K., Vallette F.M. Involvement of the N-terminus of Bax in its intracellular localization and function. FEBS Letters. 512:2002;95-100
-
(2002)
FEBS Letters
, vol.512
, pp. 95-100
-
-
Cartron, P.-F.1
Moreau, C.2
Oliver, L.3
Mayat, E.4
Meflah, K.5
Vallette, F.M.6
-
7
-
-
0038515279
-
The N-terminal end of Bax contains a mitochondrial-targeting signal
-
Cartron P.-F., Priault M., Oliver L., Meflah K., Manon S. The N-terminal end of Bax contains a mitochondrial-targeting signal. Journal of Biological Chemistry. 278:2003;11633-11641
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 11633-11641
-
-
Cartron, P.-F.1
Priault, M.2
Oliver, L.3
Meflah, K.4
Manon, S.5
-
8
-
-
0031892793
-
Molecular mechanisms of c-Jun N-terminal kinase-mediated apoptosis induced by anticarcinogenic isothiocyanates
-
Chen Y.-R., Wang W., Kong A.N.-T., Tan T.-H. Molecular mechanisms of c-Jun N-terminal kinase-mediated apoptosis induced by anticarcinogenic isothiocyanates. Journal of Biological Chemistry. 273:1998;1769-1775
-
(1998)
Journal of Biological Chemistry
, vol.273
, pp. 1769-1775
-
-
Chen, Y.-R.1
Wang, W.2
Kong, A.N.-T.3
Tan, T.-H.4
-
9
-
-
0036511358
-
Sulforaphane and its metabolite mediate growth arrest and apoptosis in human prostate cancer cells
-
Chiao J.W., Chung F.L., Kancherla R., Ahmed T., Mittelman M., Conaway C.C. Sulforaphane and its metabolite mediate growth arrest and apoptosis in human prostate cancer cells. International Journal of Oncology. 20:2002;631-636
-
(2002)
International Journal of Oncology
, vol.20
, pp. 631-636
-
-
Chiao, J.W.1
Chung, F.L.2
Kancherla, R.3
Ahmed, T.4
Mittelman, M.5
Conaway, C.C.6
-
10
-
-
0030038193
-
Chemopreventive efficacy of arylalkyl isothiocyanates and N-acetylcysteine for lung tumorigenesis in Fischer rats
-
Chung F.L., Kelloff G., Steele V., Pittman B., Zang E., Jiao D., Rigotty J., Choi C.I., Rivenson A. Chemopreventive efficacy of arylalkyl isothiocyanates and N-acetylcysteine for lung tumorigenesis in Fischer rats. Cancer Research. 56:1996;772-778
-
(1996)
Cancer Research
, vol.56
, pp. 772-778
-
-
Chung, F.L.1
Kelloff, G.2
Steele, V.3
Pittman, B.4
Zang, E.5
Jiao, D.6
Rigotty, J.7
Choi, C.I.8
Rivenson, A.9
-
11
-
-
0034525122
-
Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate
-
Chung F.L., Conaway C.C., Rao C.V., Reddy B.S. Chemoprevention of colonic aberrant crypt foci in Fischer rats by sulforaphane and phenethyl isothiocyanate. Carcinogenesis. 21:2000;2287-2291
-
(2000)
Carcinogenesis
, vol.21
, pp. 2287-2291
-
-
Chung, F.L.1
Conaway, C.C.2
Rao, C.V.3
Reddy, B.S.4
-
12
-
-
0029801147
-
Inhibition of rat liver cytochrome P450 isozymes by isothiocyanates and their conjugates: A structure-activity relationship study
-
Conaway C.C., Jiao D., Chung F.L. Inhibition of rat liver cytochrome P450 isozymes by isothiocyanates and their conjugates: A structure-activity relationship study. Carcinogenesis. 17:1996;2423-2427
-
(1996)
Carcinogenesis
, vol.17
, pp. 2423-2427
-
-
Conaway, C.C.1
Jiao, D.2
Chung, F.L.3
-
13
-
-
0033565557
-
The mitochondrial permeability transition pore and its role in cell death
-
Crompton M. The mitochondrial permeability transition pore and its role in cell death. Biochemical Journal. 341:1999;233-249
-
(1999)
Biochemical Journal
, vol.341
, pp. 233-249
-
-
Crompton, M.1
-
14
-
-
0037069929
-
Chemotherapy: Targeting the mitochondrial cell death pathway
-
Debatin K.M., Poncet D., Kroemer G. Chemotherapy: Targeting the mitochondrial cell death pathway. Oncogene. 21:2002;8786-8803
-
(2002)
Oncogene
, vol.21
, pp. 8786-8803
-
-
Debatin, K.M.1
Poncet, D.2
Kroemer, G.3
-
16
-
-
0036435610
-
Direct evidence for membrane pore formation by the apoptotic protein Bax
-
Epand R.F., Martinou J.C., Montessuit S., Epand R.M., Yip C.M. Direct evidence for membrane pore formation by the apoptotic protein Bax. Biochemical and Biophysical Research Communications. 298:2002;744-749
-
(2002)
Biochemical and Biophysical Research Communications
, vol.298
, pp. 744-749
-
-
Epand, R.F.1
Martinou, J.C.2
Montessuit, S.3
Epand, R.M.4
Yip, C.M.5
-
18
-
-
0035808553
-
The chemical diversity and distribution of glucosinolates and isothiocyanates among plants
-
Fahey J.W., Zalcmann A.T., Talalay P. The chemical diversity and distribution of glucosinolates and isothiocyanates among plants. Phytochemistry. 56:2001;5-51
-
(2001)
Phytochemistry
, vol.56
, pp. 5-51
-
-
Fahey, J.W.1
Zalcmann, A.T.2
Talalay, P.3
-
19
-
-
0025066530
-
The use of monochlorobimane to determine hepatic GSH levels and synthesis
-
Fernandez-Checa J.C., Kaplowitz N. The use of monochlorobimane to determine hepatic GSH levels and synthesis. Analytical Biochemistry. 190:1990;212-219
-
(1990)
Analytical Biochemistry
, vol.190
, pp. 212-219
-
-
Fernandez-Checa, J.C.1
Kaplowitz, N.2
-
20
-
-
0034162822
-
Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells
-
Gamet-Payrastre L., Li P., Lumeau S., Cassar G., Dupont M.A., Chevolleau S., Gasc N., Tulliez J., Terce F. Sulforaphane, a naturally occurring isothiocyanate, induces cell cycle arrest and apoptosis in HT29 human colon cancer cells. Cancer Research. 60:2000;1426-1433
-
(2000)
Cancer Research
, vol.60
, pp. 1426-1433
-
-
Gamet-Payrastre, L.1
Li, P.2
Lumeau, S.3
Cassar, G.4
Dupont, M.A.5
Chevolleau, S.6
Gasc, N.7
Tulliez, J.8
Terce, F.9
-
21
-
-
0032484008
-
Inhibition of human caspases by peptide-based and macromolecular inhibitors
-
Garcia-Calvo M., Peterson E.P., Leiting B., Ruel R., Nicholson D.W., Thornberry N.A. Inhibition of human caspases by peptide-based and macromolecular inhibitors. Journal of Biological Chemistry. 273:1998;32608-32613
-
(1998)
Journal of Biological Chemistry
, vol.273
, pp. 32608-32613
-
-
Garcia-Calvo, M.1
Peterson, E.P.2
Leiting, B.3
Ruel, R.4
Nicholson, D.W.5
Thornberry, N.A.6
-
22
-
-
0032487582
-
Regulated targeting of BAX to mitochondria
-
Goping I.S., Gross A., Lavoie J.N., Nguyen M., Jemmerson R., Roth K., Korsmeyer S.J., Shore G.C. Regulated targeting of BAX to mitochondria. Journal of Cell Biology. 143:1998;207-215
-
(1998)
Journal of Cell Biology
, vol.143
, pp. 207-215
-
-
Goping, I.S.1
Gross, A.2
Lavoie, J.N.3
Nguyen, M.4
Jemmerson, R.5
Roth, K.6
Korsmeyer, S.J.7
Shore, G.C.8
-
23
-
-
0037023739
-
TBID homooligomerizes in the mitochondrial membrane to induce apoptosis
-
Grinberg M., Sarig R., Zaltsman Y., Frumkin D., Grammatikakis N., Reuveny E., et al. tBID homooligomerizes in the mitochondrial membrane to induce apoptosis. Journal of Biological Chemistry. 277:2002;12237-12245
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 12237-12245
-
-
Grinberg, M.1
Sarig, R.2
Zaltsman, Y.3
Frumkin, D.4
Grammatikakis, N.5
Reuveny, E.6
-
24
-
-
0038177515
-
Molecular signaling in death receptor and mitochondrial pathways of apoptosis
-
Gupta S. Molecular signaling in death receptor and mitochondrial pathways of apoptosis. International Journal of Oncology. 22:2003;15-20
-
(2003)
International Journal of Oncology
, vol.22
, pp. 15-20
-
-
Gupta, S.1
-
25
-
-
0035808393
-
Rate-limiting step preceding cytochrome c release in cells primed for Fas-mediated apoptosis revealed by analysis of cellular mosaicism of respiratory changes
-
Hajek P., Villani G., Attardi G. Rate-limiting step preceding cytochrome c release in cells primed for Fas-mediated apoptosis revealed by analysis of cellular mosaicism of respiratory changes. Journal of Biological Chemistry. 276:2001;606-615
-
(2001)
Journal of Biological Chemistry
, vol.276
, pp. 606-615
-
-
Hajek, P.1
Villani, G.2
Attardi, G.3
-
26
-
-
0041810128
-
The adenine nucleotide translocase: A central component of the mitochondrial permeability transition pore and key player in cell death
-
Halestrap A.P., Brennerb C. The adenine nucleotide translocase: A central component of the mitochondrial permeability transition pore and key player in cell death. Current Medicinal Chemistry. 10:2003;1507-1525
-
(2003)
Current Medicinal Chemistry
, vol.10
, pp. 1507-1525
-
-
Halestrap, A.P.1
Brennerb, C.2
-
27
-
-
0024595042
-
Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill
-
Hansen M.B., Nielsen S.E., Berg K. Re-examination and further development of a precise and rapid dye method for measuring cell growth/cell kill. Journal of Immunological Methods. 119:1989;203-210
-
(1989)
Journal of Immunological Methods
, vol.119
, pp. 203-210
-
-
Hansen, M.B.1
Nielsen, S.E.2
Berg, K.3
-
29
-
-
0032530999
-
Essential role of p53 in phenethyl isothiocyanate-induced apoptosis
-
Haung C., Ma W.Y., Li J., Hecht S.S., Dong Z. Essential role of p53 in phenethyl isothiocyanate-induced apoptosis. Cancer Research. 58:1998;4102-4106
-
(1998)
Cancer Research
, vol.58
, pp. 4102-4106
-
-
Haung, C.1
Ma, W.Y.2
Li, J.3
Hecht, S.S.4
Dong, Z.5
-
31
-
-
0042388396
-
The roles of JNK and apoptotic signaling pathways in PEITC-mediated responses in human HT-29 colon adenocarcinoma cells
-
Hu R., Kim B.R., Chen C., Hebbar V., Kong A.N. The roles of JNK and apoptotic signaling pathways in PEITC-mediated responses in human HT-29 colon adenocarcinoma cells. Carcinogenesis. 24:2003;1361-1367
-
(2003)
Carcinogenesis
, vol.24
, pp. 1361-1367
-
-
Hu, R.1
Kim, B.R.2
Chen, C.3
Hebbar, V.4
Kong, A.N.5
-
32
-
-
0034024730
-
Calphostin C-mediated translocation and integration of Bax into mitochondria induces cytochrome c release before mitochondrial dysfunction
-
Ikemoto H., Tani E., Ozaki I., Kitagawa H., Arita N. Calphostin C-mediated translocation and integration of Bax into mitochondria induces cytochrome c release before mitochondrial dysfunction. Cell Death and Differentiation. 7:2000;511-520
-
(2000)
Cell Death and Differentiation
, vol.7
, pp. 511-520
-
-
Ikemoto, H.1
Tani, E.2
Ozaki, I.3
Kitagawa, H.4
Arita, N.5
-
33
-
-
0040298568
-
Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis
-
Janicke R.U., Sprengart M.L., Wati M.R., Porter A.G. Caspase-3 is required for DNA fragmentation and morphological changes associated with apoptosis. Journal of Biological Chemistry. 273:1998;9357-9360
-
(1998)
Journal of Biological Chemistry
, vol.273
, pp. 9357-9360
-
-
Janicke, R.U.1
Sprengart, M.L.2
Wati, M.R.3
Porter, A.G.4
-
34
-
-
0035833337
-
Bax translocation is crucial for the sensitivity of leukaemic cells to etoposide-induced apoptosis
-
Jia L., Patwari Y., Srinivasula S.M., Newland A.C., Fernandes-Alnemri T., Alnemri E.S., et al. Bax translocation is crucial for the sensitivity of leukaemic cells to etoposide-induced apoptosis. Oncogene. 20:2002;4817-4826
-
(2002)
Oncogene
, vol.20
, pp. 4817-4826
-
-
Jia, L.1
Patwari, Y.2
Srinivasula, S.M.3
Newland, A.C.4
Fernandes-Alnemri, T.5
Alnemri, E.S.6
-
35
-
-
0034613302
-
Cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1
-
Jiang X., Wang X. cytochrome c promotes caspase-9 activation by inducing nucleotide binding to Apaf-1. Journal of Biological Chemistry. 275:2000;31199-311203
-
(2000)
Journal of Biological Chemistry
, vol.275
, pp. 31199-311203
-
-
Jiang, X.1
Wang, X.2
-
36
-
-
0028345801
-
A fast kinetic method for assessing mitochondrial membrane potential in isolated hepatocytes with rhodamine 123 and flow cytometry
-
Juan G., Cavazzoni M., Saez G.T., O'Connor J.E. A fast kinetic method for assessing mitochondrial membrane potential in isolated hepatocytes with rhodamine 123 and flow cytometry. Cytometry. 15:1994;335-342
-
(1994)
Cytometry
, vol.15
, pp. 335-342
-
-
Juan, G.1
Cavazzoni, M.2
Saez, G.T.3
O'Connor, J.E.4
-
37
-
-
84943469330
-
Methodologic studies of the quantitative microdetermination of ATP in bological materials with the firefly enzyme system
-
Kalbhen D.A., Koch H.J. Methodologic studies of the quantitative microdetermination of ATP in bological materials with the firefly enzyme system. Zeitschrift Fuer Klinische Chemie und Klinische Biochemie. 5:1967;299-394
-
(1967)
Zeitschrift fuer Klinische Chemie und Klinische Biochemie
, vol.5
, pp. 299-394
-
-
Kalbhen, D.A.1
Koch, H.J.2
-
39
-
-
0037053298
-
The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c
-
Karpinich N.O., Tafani M., Rothman R.J., Russo M.A., Farber J.L. The course of etoposide-induced apoptosis from damage to DNA and p53 activation to mitochondrial release of cytochrome c. Journal of Biological Chemistry. 277:2002;16547-16552
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 16547-16552
-
-
Karpinich, N.O.1
Tafani, M.2
Rothman, R.J.3
Russo, M.A.4
Farber, J.L.5
-
40
-
-
0036289628
-
Dysfunction of rat liver mitochondria by selenite: Induction of mitochondrial permeability transition through thiol-oxidation
-
Kim T.S., Jeong D.W., Yun B.Y., Kim I.Y. Dysfunction of rat liver mitochondria by selenite: Induction of mitochondrial permeability transition through thiol-oxidation. Biochemical and Biophysical Research Communications. 294:2002;1130-1137
-
(2002)
Biochemical and Biophysical Research Communications
, vol.294
, pp. 1130-1137
-
-
Kim, T.S.1
Jeong, D.W.2
Yun, B.Y.3
Kim, I.Y.4
-
41
-
-
0017156689
-
Interaction of electrophilic alkylating agents with nucleophilic sites of mitochondria
-
Kobliakov V.A., Karamysheva A.F., Ozrina R.D., Iaguzhinskii L.S. Interaction of electrophilic alkylating agents with nucleophilic sites of mitochondria. Biokhimiia. 41:1976;1497-1503
-
(1976)
Biokhimiia
, vol.41
, pp. 1497-1503
-
-
Kobliakov, V.A.1
Karamysheva, A.F.2
Ozrina, R.D.3
Iaguzhinskii, L.S.4
-
42
-
-
0036850312
-
Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane
-
Kuwana T., Mackey M.R., Perkins G., Ellisman M.H., Latterich M., Schneiter R., et al. Bid, Bax, and lipids cooperate to form supramolecular openings in the outer mitochondrial membrane. Cell. 111:2002;331-342
-
(2002)
Cell
, vol.111
, pp. 331-342
-
-
Kuwana, T.1
MacKey, M.R.2
Perkins, G.3
Ellisman, M.H.4
Latterich, M.5
Schneiter, R.6
-
43
-
-
0036269755
-
The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase
-
Lei K., Nimnual A., Zong W.X., Kennedy N.J., Flavell R.A. The Bax subfamily of Bcl2-related proteins is essential for apoptotic signal transduction by c-Jun NH(2)-terminal kinase. Molecular Cellular Biology. 22:2002;4929-4942
-
(2002)
Molecular Cellular Biology
, vol.22
, pp. 4929-4942
-
-
Lei, K.1
Nimnual, A.2
Zong, W.X.3
Kennedy, N.J.4
Flavell, R.A.5
-
44
-
-
0036137597
-
Role of substrates in the regulation of mitochondrial function in situ
-
Leverve X.M., Fontaine E. Role of substrates in the regulation of mitochondrial function in situ. IUBMB Life. 52:2001;221-229
-
(2001)
IUBMB Life
, vol.52
, pp. 221-229
-
-
Leverve, X.M.1
Fontaine, E.2
-
45
-
-
0034718294
-
Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: A prospective study of men in Shanghai, China
-
London S.J., Yuan J.M., Chung F.L., Gao J.T., Coetzee G.A., Ross R.K., et al. Isothiocyanates, glutathione S-transferase M1 and T1 polymorphisms, and lung-cancer risk: A prospective study of men in Shanghai, China. Lancet. 356:2000;724-729
-
(2000)
Lancet
, vol.356
, pp. 724-729
-
-
London, S.J.1
Yuan, J.M.2
Chung, F.L.3
Gao, J.T.4
Coetzee, G.A.5
Ross, R.K.6
-
46
-
-
0035890335
-
Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate
-
Makin G.W.J., Corfe B.M., Griffiths G.J., Thistletwaite A., Hickman J.A., Dive C. Damage-induced Bax N-terminal change, translocation to mitochondria and formation of Bax dimers/complexes occur regardless of cell fate. EMBO Journal. 20:2001;6306-6315
-
(2001)
EMBO Journal
, vol.20
, pp. 6306-6315
-
-
Makin, G.W.J.1
Corfe, B.M.2
Griffiths, G.J.3
Thistletwaite, A.4
Hickman, J.A.5
Dive, C.6
-
47
-
-
0032566649
-
Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis
-
Marzo I., Brenner C., Zamzami N., Jurgensmeier J.M., Susin S.A. Bax and adenine nucleotide translocator cooperate in the mitochondrial control of apoptosis. Science. 281:1998;2027-2031
-
(1998)
Science
, vol.281
, pp. 2027-2031
-
-
Marzo, I.1
Brenner, C.2
Zamzami, N.3
Jurgensmeier, J.M.4
Susin, S.A.5
-
48
-
-
0036006511
-
Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death
-
McClintock D.S., Santore M.T., Lee V.Y., Brunelle J., Budinger J.R., Zong X.Z., et al. Bcl-2 family members and functional electron transport chain regulate oxygen deprivation-induced cell death. Molecular Cellular Biology. 22:2002;94-104
-
(2002)
Molecular Cellular Biology
, vol.22
, pp. 94-104
-
-
McClintock, D.S.1
Santore, M.T.2
Lee, V.Y.3
Brunelle, J.4
Budinger, J.R.5
Zong, X.Z.6
-
49
-
-
0037040918
-
Involvement of the mitochondrial death pathway in chemopreventive benzyl isothiocyanate-induced apoptosis
-
Nakamura Y., Kawakami M., Yoshihiro A., Miyoshi N., Ohigashi H., Kawai K., et al. Involvement of the mitochondrial death pathway in chemopreventive benzyl isothiocyanate-induced apoptosis. Journal of Biological Chemistry. 277:2002;8492-8499
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 8492-8499
-
-
Nakamura, Y.1
Kawakami, M.2
Yoshihiro, A.3
Miyoshi, N.4
Ohigashi, H.5
Kawai, K.6
-
50
-
-
0032422488
-
Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria
-
Narita M., Shimizu S., ITO T., Chittenden T., Lutz R.J. Bax interacts with the permeability transition pore to induce permeability transition and cytochrome c release in isolated mitochondria. Proceedings of the National Academy of Science USA. 95:1998;14681-14686
-
(1998)
Proceedings of the National Academy of Science USA
, vol.95
, pp. 14681-14686
-
-
Narita, M.1
Shimizu, S.2
Ito, T.3
Chittenden, T.4
Lutz, R.J.5
-
51
-
-
0033522391
-
Conformation of the Bax C-terminus regulates subcellular location and cell death
-
Nechushtan A., Smith C.L., Hsu Y.-T., Youle R.J. Conformation of the Bax C-terminus regulates subcellular location and cell death. EMBO Journal. 18:1999;2330-2341
-
(1999)
EMBO Journal
, vol.18
, pp. 2330-2341
-
-
Nechushtan, A.1
Smith, C.L.2
Hsu, Y.-T.3
Youle, R.J.4
-
52
-
-
0029068871
-
Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis
-
Nicholson D.W., Ali A., Thornberry N.A., Vaillancourt J.P., Ding C.K., Gallant M., et al. Identification and inhibition of the ICE/CED-3 protease necessary for mammalian apoptosis. Nature. 376:1995;37-43
-
(1995)
Nature
, vol.376
, pp. 37-43
-
-
Nicholson, D.W.1
Ali, A.2
Thornberry, N.A.3
Vaillancourt, J.P.4
Ding, C.K.5
Gallant, M.6
-
53
-
-
0025726216
-
A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry
-
Nicoletti I., Migliorati G., Pagliacci M.C., Grignani F., Riccardi C. A rapid and simple method for measuring thymocyte apoptosis by propidium iodide staining and flow cytometry. Journal of Immunological Methods. 139:1991;271-279
-
(1991)
Journal of Immunological Methods
, vol.139
, pp. 271-279
-
-
Nicoletti, I.1
Migliorati, G.2
Pagliacci, M.C.3
Grignani, F.4
Riccardi, C.5
-
54
-
-
0035929341
-
Regulation of apoptosis by respiration: Cytochrome c release by respiratory substrates
-
Nishimura G., Proske R.J., Doyama H., Higuchi M. Regulation of apoptosis by respiration: Cytochrome c release by respiratory substrates. FEBS Letters. 505:2001;399-404
-
(2001)
FEBS Letters
, vol.505
, pp. 399-404
-
-
Nishimura, G.1
Proske, R.J.2
Doyama, H.3
Higuchi, M.4
-
55
-
-
0037449733
-
14-3-3 interacts directly with and negatively regulates pro-apoptotic Bax
-
Nomura M., Shimizu S., Sugiyama T., Narita M., Ito T., Matsuda H., et al. 14-3-3 interacts directly with and negatively regulates pro-apoptotic Bax. Journal of Biological Chemistry. 278:2003;2058-2065
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 2058-2065
-
-
Nomura, M.1
Shimizu, S.2
Sugiyama, T.3
Narita, M.4
Ito, T.5
Matsuda, H.6
-
56
-
-
0032571294
-
Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore
-
Pastorino J.G., Chen S.-T., Tafani M., Snyder J.W., Farber J.L. Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore. Journal of Biological Chemistry. 273:1998;7770-7775
-
(1998)
Journal of Biological Chemistry
, vol.273
, pp. 7770-7775
-
-
Pastorino, J.G.1
Chen, S.-T.2
Tafani, M.3
Snyder, J.W.4
Farber, J.L.5
-
57
-
-
0033615649
-
Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore
-
Pastorino J.G., Tafani M., Rothman R.J., Marcineviciute A., Hoek J.B., Farber J.L., et al. Functional consequences of the sustained or transient activation by Bax of the mitochondrial permeability transition pore. Journal of Biological Chemistry. 274:1999;31734-31739
-
(1999)
Journal of Biological Chemistry
, vol.274
, pp. 31734-31739
-
-
Pastorino, J.G.1
Tafani, M.2
Rothman, R.J.3
Marcineviciute, A.4
Hoek, J.B.5
Farber, J.L.6
-
58
-
-
0035956426
-
A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast
-
Pavlov E.V., Priault M., Pietkiewicz D., Cheng E.H.Y., Antonsson B., Manon S., et al. A novel, high conductance channel of mitochondria linked to apoptosis in mammalian cells and Bax expression in yeast. Journal of Cell Biology. 155:2001;725-731
-
(2001)
Journal of Cell Biology
, vol.155
, pp. 725-731
-
-
Pavlov, E.V.1
Priault, M.2
Pietkiewicz, D.3
Cheng, E.H.Y.4
Antonsson, B.5
Manon, S.6
-
59
-
-
0032815221
-
Comparison of the effects of Bax-expression in yeast under fermentative and respiratory conditions: Investigation of the role of adenine nucleotides carrier and cytochrome c
-
Priault M., Camougrand N., Chaudhuri B., Schaeffer J., Manon S. Comparison of the effects of Bax-expression in yeast under fermentative and respiratory conditions: Investigation of the role of adenine nucleotides carrier and cytochrome c. FEBS Letters. 456:1999;232-238
-
(1999)
FEBS Letters
, vol.456
, pp. 232-238
-
-
Priault, M.1
Camougrand, N.2
Chaudhuri, B.3
Schaeffer, J.4
Manon, S.5
-
60
-
-
0343262657
-
Myrosinase: Gene family evolution and herbivore defence in Brassicaceae
-
Rask L., Andreasson E., Ekbom B., Eriksson S., Pontoppidan B., Meijer J. Myrosinase: Gene family evolution and herbivore defence in Brassicaceae. Plant Molecular Biology. 42:2000;93-113
-
(2000)
Plant Molecular Biology
, vol.42
, pp. 93-113
-
-
Rask, L.1
Andreasson, E.2
Ekbom, B.3
Eriksson, S.4
Pontoppidan, B.5
Meijer, J.6
-
61
-
-
0033746135
-
7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes
-
Rose P., Faulkner K., Williamson G., Mithen R. 7-Methylsulfinylheptyl and 8-methylsulfinyloctyl isothiocyanates from watercress are potent inducers of phase II enzymes. Carcinogenesis. 21:2000;1983-1988
-
(2000)
Carcinogenesis
, vol.21
, pp. 1983-1988
-
-
Rose, P.1
Faulkner, K.2
Williamson, G.3
Mithen, R.4
-
62
-
-
0345120940
-
Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives
-
Scaduto R.C. Jr., Grotyohann L.W. Measurement of mitochondrial membrane potential using fluorescent rhodamine derivatives. Biophysical Journal. 76:1999;469-477
-
(1999)
Biophysical Journal
, vol.76
, pp. 469-477
-
-
Scaduto Jr., R.C.1
Grotyohann, L.W.2
-
63
-
-
0036139981
-
Respiratory chain supercomplexes
-
Schagger H. Respiratory chain supercomplexes. IUBMB Life. 52:2001;119-128
-
(2001)
IUBMB Life
, vol.52
, pp. 119-128
-
-
Schagger, H.1
-
65
-
-
0029977549
-
2+ release from intact rat liver mitochondria
-
2+ release from intact rat liver mitochondria. Biochemistry. 35:1996;4524-4528
-
(1996)
Biochemistry
, vol.35
, pp. 4524-4528
-
-
Schweizer, M.1
Richter, C.2
-
67
-
-
0037199456
-
Peptides derived from BH3 domains of Bcl-2 family members: A comparative analysis of inhibition of Bcl-2, Bcl-x(L) and Bax oligomerization, induction of cytochrome c release and activation of cell death
-
Shangary S., Johnson D.E. Peptides derived from BH3 domains of Bcl-2 family members: A comparative analysis of inhibition of Bcl-2, Bcl-x(L) and Bax oligomerization, induction of cytochrome c release and activation of cell death. Biochemistry. 41:2002;9485-9495
-
(2002)
Biochemistry
, vol.41
, pp. 9485-9495
-
-
Shangary, S.1
Johnson, D.E.2
-
68
-
-
0032906648
-
Sodium selenite-induced oxidative stress and apoptosis in human hepatoma HepG2 cells
-
Shen H.M., Yang C.F., Ong C.N. Sodium selenite-induced oxidative stress and apoptosis in human hepatoma HepG2 cells. International Journal of Cancer. 81:1999;820-828
-
(1999)
International Journal of Cancer
, vol.81
, pp. 820-828
-
-
Shen, H.M.1
Yang, C.F.2
Ong, C.N.3
-
69
-
-
0033519705
-
Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC
-
Shimizu S., Narita M., Tsujimoto Y. Bcl-2 family proteins regulate the release of apoptogenic cytochrome c by the mitochondrial channel VDAC. Nature. 399:1999;483-487
-
(1999)
Nature
, vol.399
, pp. 483-487
-
-
Shimizu, S.1
Narita, M.2
Tsujimoto, Y.3
-
70
-
-
0033601746
-
Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner
-
Slee E.A., Harte M.T., Kluck R.M., Wolf B.B., Casiano C.A. Ordering the cytochrome c-initiated caspase cascade: Hierarchical activation of caspases-2, -3, -6, -7, -8, and -10 in a caspase-9-dependent manner. Journal of Cell Biology. 144:1999;281-292
-
(1999)
Journal of Cell Biology
, vol.144
, pp. 281-292
-
-
Slee, E.A.1
Harte, M.T.2
Kluck, R.M.3
Wolf, B.B.4
Casiano, C.A.5
-
71
-
-
0034866507
-
Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potential
-
Smaili S.S., Hsu Y.-T., Sanders K.M., Russell J.T., Youle R.J. Bax translocation to mitochondria subsequent to a rapid loss of mitochondrial membrane potential. Cell Death and Differentiation. 8:2001;909-920
-
(2001)
Cell Death and Differentiation
, vol.8
, pp. 909-920
-
-
Smaili, S.S.1
Hsu, Y.-T.2
Sanders, K.M.3
Russell, J.T.4
Youle, R.J.5
-
73
-
-
0033713002
-
Structure of Bax: Coregulation of dimer formation and intracellular localization
-
Suzuki M., Youle R.J., Tjandra N. Structure of Bax: Coregulation of dimer formation and intracellular localization. Cell. 103:2000;645-654
-
(2000)
Cell
, vol.103
, pp. 645-654
-
-
Suzuki, M.1
Youle, R.J.2
Tjandra, N.3
-
74
-
-
0037147147
-
Regulation of intracellular pH mediates Bax activation in HeLa cells treated with staurosporine or tumor necrosis factor-alpha
-
Tafani M., Cohn J.A., Karpinich N.O., Rothman R.J., Russo M.A.J.L. Regulation of intracellular pH mediates Bax activation in HeLa cells treated with staurosporine or tumor necrosis factor-alpha. Journal of Biological Chemistry. 277:2002;49569-49576
-
(2002)
Journal of Biological Chemistry
, vol.277
, pp. 49569-49576
-
-
Tafani, M.1
Cohn, J.A.2
Karpinich, N.O.3
Rothman, R.J.4
Russo, M.A.J.L.5
-
75
-
-
0027489228
-
Oxidative damage to mitochondria is mediated by the Ca(2+)-dependent inner-membrane permeability transition
-
Takeyama N., Matsuo N., Tanaka T. Oxidative damage to mitochondria is mediated by the Ca(2+)-dependent inner-membrane permeability transition. Biochemical Journal. 294:1993;719-725
-
(1993)
Biochemical Journal
, vol.294
, pp. 719-725
-
-
Takeyama, N.1
Matsuo, N.2
Tanaka, T.3
-
76
-
-
0030849093
-
A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis
-
Thornberry N.A., Rano T.A., Peterson E.P., Rasper D.M., Timkey T., Garcia-Calvo M., et al. A combinatorial approach defines specificities of members of the caspase family and granzyme B. Functional relationships established for key mediators of apoptosis. Journal of Biological Chemistry. 272:1997;17907-17911
-
(1997)
Journal of Biological Chemistry
, vol.272
, pp. 17907-17911
-
-
Thornberry, N.A.1
Rano, T.A.2
Peterson, E.P.3
Rasper, D.M.4
Timkey, T.5
Garcia-Calvo, M.6
-
77
-
-
2442429306
-
JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins
-
Tsuruta F., Sunayama J., Mori Y., Hattori S., Shimizu S., Tsujimoto Y., et al. JNK promotes Bax translocation to mitochondria through phosphorylation of 14-3-3 proteins. EMBO Journal. 23:2004;1889-1899
-
(2004)
EMBO Journal
, vol.23
, pp. 1889-1899
-
-
Tsuruta, F.1
Sunayama, J.2
Mori, Y.3
Hattori, S.4
Shimizu, S.5
Tsujimoto, Y.6
-
78
-
-
0038363593
-
N-terminal deletion augments the cell-death-inducing activity of BAX in adenoviral gene delivery to nonsmall cell lung cancers
-
Usui K., Saijo Y., Narumi K., Koyama S., Maemondo M., Kikuchi T., et al. N-terminal deletion augments the cell-death-inducing activity of BAX in adenoviral gene delivery to nonsmall cell lung cancers. Oncogene. 22:2003;2655-2663
-
(2003)
Oncogene
, vol.22
, pp. 2655-2663
-
-
Usui, K.1
Saijo, Y.2
Narumi, K.3
Koyama, S.4
Maemondo, M.5
Kikuchi, T.6
-
80
-
-
0037424429
-
Lack of tyrosine nitration by hypochlorous acid in the presence of physiological concentrations of nitrite. Implications for the role of nitryl chloride in tyrosine nitration in vivo
-
Whiteman M., Siau J.L., Halliwell B. Lack of tyrosine nitration by hypochlorous acid in the presence of physiological concentrations of nitrite. Implications for the role of nitryl chloride in tyrosine nitration in vivo. Journal of Biological Chemistry. 278:2003;8380-8384
-
(2003)
Journal of Biological Chemistry
, vol.278
, pp. 8380-8384
-
-
Whiteman, M.1
Siau, J.L.2
Halliwell, B.3
-
81
-
-
0030780106
-
Movement of Bax from the cytosol to mitochondria during apoptosis
-
Wolter K.G., Hsu Y.-T., Smith C.L., Nechushtan A., Xi X.G., Youle R.J. Movement of Bax from the cytosol to mitochondria during apoptosis. Journal of Cell Biology. 139:1997;1281-1292
-
(1997)
Journal of Cell Biology
, vol.139
, pp. 1281-1292
-
-
Wolter, K.G.1
Hsu, Y.-T.2
Smith, C.L.3
Nechushtan, A.4
G X. Xi5
Youle, R.J.6
-
82
-
-
0036644873
-
Phenethyl isothiocyanate-induced apoptosis in p53-deficient PC-3 human prostate cancer cell line is mediated by extracellular signal-regulated kinases
-
Xiao D., Singh S.V. Phenethyl isothiocyanate-induced apoptosis in p53-deficient PC-3 human prostate cancer cell line is mediated by extracellular signal-regulated kinases. Cancer Research. 62:2002;3615-3619
-
(2002)
Cancer Research
, vol.62
, pp. 3615-3619
-
-
Xiao, D.1
Singh, S.V.2
-
83
-
-
0034662433
-
Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro
-
Xu K., Thornalley P. Studies on the mechanism of the inhibition of human leukaemia cell growth by dietary isothiocyanates and their cysteine adducts in vitro. Biochemical Pharmacology. 60:2000;221-231
-
(2000)
Biochemical Pharmacology
, vol.60
, pp. 221-231
-
-
Xu, K.1
Thornalley, P.2
-
84
-
-
0035793801
-
Signal transduction activated by the cancer chemopreventive isothiocyanates: Cleavage of BID protein, tyrosine phosphorylation and activation of JNK
-
Xu K., Thornalley P.J. Signal transduction activated by the cancer chemopreventive isothiocyanates: Cleavage of BID protein, tyrosine phosphorylation and activation of JNK. British Journal of Cancer. 84:2001;670-673
-
(2001)
British Journal of Cancer
, vol.84
, pp. 670-673
-
-
Xu, K.1
Thornalley, P.J.2
-
85
-
-
0036142924
-
Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis
-
Yang Y.M., Conaway C.C., Chiao J.W., Wang C.X., Amin S., Whysner J., et al. Inhibition of benzo(a)pyrene-induced lung tumorigenesis in A/J mice by dietary N-acetylcysteine conjugates of benzyl and phenethyl isothiocyanates during the postinitiation phase is associated with activation of mitogen-activated protein kinases and p53 activity and induction of apoptosis. Cancer Research. 62:2002;2-7
-
(2002)
Cancer Research
, vol.62
, pp. 2-7
-
-
Yang, Y.M.1
Conaway, C.C.2
Chiao, J.W.3
Wang, C.X.4
Amin, S.5
Whysner, J.6
-
86
-
-
0028326168
-
Anticarcinogenic activities of organic isothiocyanates: Chemistry and mechanisms
-
Zhang Y., Talalay P. Anticarcinogenic activities of organic isothiocyanates: Chemistry and mechanisms. Cancer Research. 54:1994;1976s-1981s
-
(1994)
Cancer Research
, vol.54
-
-
Zhang, Y.1
Talalay, P.2
-
87
-
-
0032532317
-
Mechanism of differential potencies of isothiocyanates as inducers of anticarcinogenic Phase 2 enzymes
-
Zhang Y., Talalay P. Mechanism of differential potencies of isothiocyanates as inducers of anticarcinogenic Phase 2 enzymes. Cancer Research. 58:1998;4632-4639
-
(1998)
Cancer Research
, vol.58
, pp. 4632-4639
-
-
Zhang, Y.1
Talalay, P.2
-
88
-
-
0035094701
-
Molecular mechanism of rapid cellular accumulation of anticarcinogenic isothiocyanates
-
Zhang Y. Molecular mechanism of rapid cellular accumulation of anticarcinogenic isothiocyanates. Carcinogenesis. 22:2001;425-431
-
(2001)
Carcinogenesis
, vol.22
, pp. 425-431
-
-
Zhang, Y.1
-
89
-
-
0034798401
-
Dietary isothiocyanates, glutathione S-transferase -M1, -T1 polymorphisms and lung cancer risk among Chinese women in Singapore
-
Zhao B., Seow A., Lee E.J., Poh W.T., Teh M., Eng P., et al. Dietary isothiocyanates, glutathione S-transferase -M1, -T1 polymorphisms and lung cancer risk among Chinese women in Singapore. Cancer Epidemiology Biomarkers and Prevention. 10:2001;1063-1067
-
(2001)
Cancer Epidemiology Biomarkers and Prevention
, vol.10
, pp. 1063-1067
-
-
Zhao, B.1
Seow, A.2
Lee, E.J.3
Poh, W.T.4
Teh, M.5
Eng, P.6
|