Signal transduction activated by the cancer chemopreventive isothiocyanates: Cleavage of BID protein, tyrosine phosphorylation and activation of JNK

British Journal of Cancer

Volumn 84, Issue 5, 2001, Pages 670-673

  Xu, K ^a   Thornalley, P J ^a  

^a UNIVERSITY OF ESSEX   (United Kingdom)

Author keywords

Apoptosis; BID; Isothiocyanate; JNK; Tyrosine phosphorylation

Indexed keywords

ALLYL ISOTHIOCYANATE; BENZYLOXYCARBONYLVALYLALANYLASPARTYL FLUOROMETHYL KETONE; CASPASE 3; CASPASE 8; CASPASE INHIBITOR; CELL PROTEIN; GLUTATHIONE; PHENETHYL ISOTHIOCYANATE; PROTEIN BID; PROTEIN TYROSINE PHOSPHATASE; STRESS ACTIVATED PROTEIN KINASE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CHEMOPROPHYLAXIS; CONTROLLED STUDY; ENZYME ACTIVITY; ENZYME INHIBITION; HUMAN; HUMAN CELL; LEUKEMIA CELL; POLYACRYLAMIDE GEL ELECTROPHORESIS; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; SIGNAL TRANSDUCTION;

AMINO ACID CHLOROMETHYL KETONES; ANTICARCINOGENIC AGENTS; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARRIER PROTEINS; CYSTEINE PROTEINASE INHIBITORS; ENZYME ACTIVATION; ENZYME INHIBITORS; HL-60 CELLS; HUMANS; ISOTHIOCYANATES; JNK MITOGEN-ACTIVATED PROTEIN KINASES; MITOGEN-ACTIVATED PROTEIN KINASES; NEOPLASMS; PHOSPHORYLATION; PHOSPHOTYROSINE; SIGNAL TRANSDUCTION;

EID: 0035793801     PISSN: 00070920     EISSN: None     Source Type: Journal    
DOI: 10.1054/bjoc.2000.1636     Document Type: Article

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