메뉴 건너뛰기




Volumn 103, Issue 2, 1997, Pages 79-129

A review of mechanisms underlying anticarcinogenicity by brassica vegetables

Author keywords

Anticarcinogenesis; Brassica vegetables; Glucosinolates; Indoles; Isothiocyanates

Indexed keywords

GLUCOSINOLATE; INDOLE DERIVATIVE; ISOTHIOCYANIC ACID DERIVATIVE;

EID: 0031588808     PISSN: 00092797     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0009-2797(96)03745-3     Document Type: Review
Times cited : (559)

References (220)
  • 1
    • 0026229557 scopus 로고
    • Vegetables, fruit, and cancer. I. Epidemiology
    • [1] K.A. Steinmetz and J.D. Potter, Vegetables, fruit, and cancer. I. Epidemiology, Cancer Causes Control, 2 (1991) 325-357.
    • (1991) Cancer Causes Control , vol.2 , pp. 325-357
    • Steinmetz, K.A.1    Potter, J.D.2
  • 2
    • 0026701521 scopus 로고
    • Fruit, vegetables, and cancer prevention: A review of the epidemiological evidence
    • [2] G. Block, B. Patterson and A. Subar, Fruit, vegetables, and cancer prevention: a review of the epidemiological evidence, Nutr. Cancer, 18 (1992) 1-29.
    • (1992) Nutr. Cancer , vol.18 , pp. 1-29
    • Block, G.1    Patterson, B.2    Subar, A.3
  • 3
    • 0024355849 scopus 로고
    • Prevention of cancer: Vegetables and plants
    • [3] G. Hocman, Prevention of cancer: vegetables and plants, Comp. Biochem. Physiol., 93B (1989) 201-212.
    • (1989) Comp. Biochem. Physiol. , vol.93 B , pp. 201-212
    • Hocman, G.1
  • 4
    • 0026246632 scopus 로고
    • Vegetables, fruit, and cancer, II. Mechanisms
    • [4] K.A. Steinmetz and J.D. Potter, Vegetables, fruit, and cancer, II. Mechanisms, Cancer Causes Control, 2 (1991) 427-44
    • (1991) Cancer Causes Control , vol.2 , pp. 427-444
    • Steinmetz, K.A.1    Potter, J.D.2
  • 5
    • 0027516446 scopus 로고
    • Cancer-protective factors in fruits and vegetables: Biochemical and biological background
    • [5] L.O. Dragsted, M. Strube and J.C. Larsen, Cancer-protective factors in fruits and vegetables: biochemical and biological background, Pharmacol. Toxicol., 72 Suppl 1 (1993) 116-135.
    • (1993) Pharmacol. Toxicol. , vol.72 , Issue.SUPPL. 1 , pp. 116-135
    • Dragsted, L.O.1    Strube, M.2    Larsen, J.C.3
  • 6
    • 0026590679 scopus 로고
    • Inhibition of carcinogenesis by minor dietary constituents
    • [6] L.W. Wattenberg, Inhibition of carcinogenesis by minor dietary constituents, Cancer Res., 52 (1992) 2085s-2091s.
    • (1992) Cancer Res. , vol.52
    • Wattenberg, L.W.1
  • 7
    • 77950285475 scopus 로고
    • Glucosinolates and their breakdown products in food and food plants
    • [7] G.R. Fenwick, R.K. Heany and W.J. Mullin, Glucosinolates and their breakdown products in food and food plants. CRC Crit. Rev. Food Sci. Nutr., 18 (1983) 123-201.
    • (1983) CRC Crit. Rev. Food Sci. Nutr. , vol.18 , pp. 123-201
    • Fenwick, G.R.1    Heany, R.K.2    Mullin, W.J.3
  • 8
    • 0000258168 scopus 로고
    • Inhibitory effects by α-naphthyl-isothiocyanate on development of hepatonoma in rats treated with 3′-methyl-4-dimethyl-aminoazobenzene
    • [8] S. Sasaki, Inhibitory effects by α-naphthyl-isothiocyanate on development of hepatonoma in rats treated with 3′-methyl-4-dimethyl-aminoazobenzene, J. Nara. Med. Assoc., 14 (1963) 101-115.
    • (1963) J. Nara. Med. Assoc. , vol.14 , pp. 101-115
    • Sasaki, S.1
  • 9
    • 0013966221 scopus 로고
    • Influence of α-naphthyl-isothiocyanate on liver tumorigenesis in rats ingesting ethionine and N-2-fluorenylacetamide
    • [9] H. Sidransky, N. Ito and E. Verney, Influence of α-naphthyl-isothiocyanate on liver tumorigenesis in rats ingesting ethionine and N-2-fluorenylacetamide, J. Nat. Cancer Inst., 37 (1966) 677-686.
    • (1966) J. Nat. Cancer Inst. , vol.37 , pp. 677-686
    • Sidransky, H.1    Ito, N.2    Verney, E.3
  • 10
    • 0344706292 scopus 로고
    • Glucosinolates and their breakdown products in cruciferous crops, foods and feedingstuffs
    • [10] G.R. Fenwick and R.K. Heany, Glucosinolates and their breakdown products in cruciferous crops, foods and feedingstuffs, Food Chem., 11 (1983) 249-271.
    • (1983) Food Chem. , vol.11 , pp. 249-271
    • Fenwick, G.R.1    Heany, R.K.2
  • 12
    • 13344255744 scopus 로고
    • De consumptie van afzonderlijke produkten door Nederlandse bevolkingsgroepen
    • TNO, Zeist
    • [12] C. Kistemaker, E.J.M. Aarnink and K.F.A.M. Hulshof, De consumptie van afzonderlijke produkten door Nederlandse bevolkingsgroepen. Voedselconsumptiepeiling 1992, TNO, Zeist, 1993.
    • (1992) Voedselconsumptiepeiling
    • Kistemaker, C.1    Aarnink, E.J.M.2    Hulshof, K.F.A.M.3
  • 13
    • 84985387077 scopus 로고
    • An estimate of the mean daily intake of glucosinolates from cruciferous vegetables in the UK
    • [13] K. Sones, R.K. Heany and G.R. Fenwick, An estimate of the mean daily intake of glucosinolates from cruciferous vegetables in the UK, J. Sci. Food Agric., 35 (1984) 712-720.
    • (1984) J. Sci. Food Agric. , vol.35 , pp. 712-720
    • Sones, K.1    Heany, R.K.2    Fenwick, G.R.3
  • 14
    • 0000044077 scopus 로고
    • Formation of indole glucosinolate breakdown products in autolyzed, steamed, and cooked Brassica vegetables
    • [14] B.A. Slominski and L.D. Campbell, Formation of indole glucosinolate breakdown products in autolyzed, steamed, and cooked Brassica vegetables, J. Agric. Food Chem., 37 (1989) 1297-1302.
    • (1989) J. Agric. Food Chem. , vol.37 , pp. 1297-1302
    • Slominski, B.A.1    Campbell, L.D.2
  • 15
    • 0026341134 scopus 로고
    • Effects of high levels of Brussels sprouts in the diet of rats
    • [15] A.P. de Groot, M.I. Willems and R.H. de Vos, Effects of high levels of Brussels sprouts in the diet of rats, Food Chem. Toxicol., 29 (1991) 829-837.
    • (1991) Food Chem. Toxicol. , vol.29 , pp. 829-837
    • De Groot, A.P.1    Willems, M.I.2    De Vos, R.H.3
  • 16
    • 84985383188 scopus 로고
    • Glucosinolates in Brassica vegetables. Analysis of twenty-seven cauliflower cultivars (Brassica oleracea L. var. botrytis subvar. cauliflora DC)
    • [16] K. Sones, R.K. Heany and G.R. Fenwick, Glucosinolates in Brassica vegetables. Analysis of twenty-seven cauliflower cultivars (Brassica oleracea L. var. botrytis subvar. cauliflora DC), J. Sci. Food Agric., 35 (1984) 762-766.
    • (1984) J. Sci. Food Agric. , vol.35 , pp. 762-766
    • Sones, K.1    Heany, R.K.2    Fenwick, G.R.3
  • 17
    • 0023845479 scopus 로고
    • Chemical and biological properties of indole glucosinolates (glucobrassicins): A review
    • [17] R. McDanell and A.E.M. McLean, Chemical and biological properties of indole glucosinolates (glucobrassicins): a review, Food Chem. Toxicol., 26 (1988) 59-70.
    • (1988) Food Chem. Toxicol. , vol.26 , pp. 59-70
    • McDanell, R.1    McLean, A.E.M.2
  • 18
    • 0024197707 scopus 로고
    • The effect of processing conditions on glucosinolates in cruciferous vegetables
    • [18] R.H. de Vos and W.G.H. Blijleven, The effect of processing conditions on glucosinolates in cruciferous vegetables, Z. Lebensm. Unters. Forsch., 187 (1988) 525-529.
    • (1988) Z. Lebensm. Unters. Forsch. , vol.187 , pp. 525-529
    • De Vos, R.H.1    Blijleven, W.G.H.2
  • 19
    • 0027892169 scopus 로고
    • Ascorbigen and other indole-derived compounds from Brassica vegetables and their analogs as anticarcinogenic and immunomodulating agents
    • [19] M.N. Preobrazhenskaya, V.M. Bukhman, A.M. Korolev and S.A. Efimov, Ascorbigen and other indole-derived compounds from Brassica vegetables and their analogs as anticarcinogenic and immunomodulating agents, Pharmacol. Ther., 60 (1993) 301-313.
    • (1993) Pharmacol. Ther. , vol.60 , pp. 301-313
    • Preobrazhenskaya, M.N.1    Bukhman, V.M.2    Korolev, A.M.3    Efimov, S.A.4
  • 20
    • 0000411522 scopus 로고
    • Review of analysis of glucosinolates: Analytical methodology for determining glucosinolate composition and content
    • [20] D.I. McGregor, W.J. Mullin and G.R. Fenwick, Review of analysis of glucosinolates: analytical methodology for determining glucosinolate composition and content, J. Assoc. Off. Anal. Chem., 66 (1983) 825-849.
    • (1983) J. Assoc. Off. Anal. Chem. , vol.66 , pp. 825-849
    • McGregor, D.I.1    Mullin, W.J.2    Fenwick, G.R.3
  • 21
    • 0026425585 scopus 로고
    • Chemical and physical carcinogenesis: Advances and perspectives for the 1990s
    • [21] C.C. Harris, Chemical and physical carcinogenesis: advances and perspectives for the 1990s, Cancer Res., 51 (1991) 5023s-5044s.
    • (1991) Cancer Res. , vol.51
    • Harris, C.C.1
  • 22
    • 0027755517 scopus 로고
    • Mechanisms of antimutagenesis and anticarcinogenesis: Role in primary prevention
    • G. Bronzetti, H. Hayatsu, S. de Flora, M.D. Waters and D.M. Shankel (Eds), Plenum Press, New York
    • [22] S. de Flora, A. Izzotti and C. Bennicelli, Mechanisms of antimutagenesis and anticarcinogenesis: role in primary prevention. in: G. Bronzetti, H. Hayatsu, S. de Flora, M.D. Waters and D.M. Shankel (Eds), Antimutagenesis and anticarcinogenesis mechanisms III, Plenum Press, New York, 1993, pp. 1-16.
    • (1993) Antimutagenesis and Anticarcinogenesis Mechanisms , vol.3 , pp. 1-16
    • De Flora, S.1    Izzotti, A.2    Bennicelli, C.3
  • 25
    • 0025021731 scopus 로고
    • Identification of candidate cancer chemopreventive agents and their evaluation in animal models and human clinical trials: A review
    • [25] C. Boone, G.J. Kelloff and W.E. Malone, Identification of candidate cancer chemopreventive agents and their evaluation in animal models and human clinical trials: a review, Cancer Res., 50 (1990) 2-9.
    • (1990) Cancer Res. , vol.50 , pp. 2-9
    • Boone, C.1    Kelloff, G.J.2    Malone, W.E.3
  • 26
    • 0028326168 scopus 로고
    • Anticarcinogenic activities of organic isothiocyanates: Chemistry and mechanisms
    • [26] Y. Zhang and P. Talalay, Anticarcinogenic activities of organic isothiocyanates: chemistry and mechanisms, Cancer Res., 54 (1994) 1976s-1981s.
    • (1994) Cancer Res. , vol.54
    • Zhang, Y.1    Talalay, P.2
  • 28
    • 0027566498 scopus 로고
    • Dietary non-nutritive cancer protective factors
    • [28] E.B. Thorling, Dietary non-nutritive cancer protective factors, Eur. J. Cancer Prev., 2 (1993) 95-103.
    • (1993) Eur. J. Cancer Prev. , vol.2 , pp. 95-103
    • Thorling, E.B.1
  • 29
    • 0026589840 scopus 로고
    • Rapid detection of inducers of enzymes that protect against carcinogens
    • [29] H.J. Prochaska, A.B. Santamaria and P. Talalay, Rapid detection of inducers of enzymes that protect against carcinogens. Proc. Natl. Acad. Sci., 89 (1992) 2394-2398.
    • (1992) Proc. Natl. Acad. Sci. , vol.89 , pp. 2394-2398
    • Prochaska, H.J.1    Santamaria, A.B.2    Talalay, P.3
  • 31
    • 84984471060 scopus 로고
    • Effects of glucosinolate breakdown products on the hepatic biotransformation system in male rats
    • [31] B. Ozierenski, R. Plass and H.-J. Lewerenz, Effects of glucosinolate breakdown products on the hepatic biotransformation system in male rats, Nahrung, 37 (1993) 5-14.
    • (1993) Nahrung , vol.37 , pp. 5-14
    • Ozierenski, B.1    Plass, R.2    Lewerenz, H.-J.3
  • 32
    • 0027421027 scopus 로고
    • Effects of 1-isothiocyanato-3-(methylsulfinyl)-propane on xenobiotic metabolizing enzymes in rats
    • [32] A.M. Kore, E.H. Jeffery and M.A. Wallig, Effects of 1-isothiocyanato-3-(methylsulfinyl)-propane on xenobiotic metabolizing enzymes in rats, Food Chem. Toxicol., 31 (1991) 723-729.
    • (1991) Food Chem. Toxicol. , vol.31 , pp. 723-729
    • Kore, A.M.1    Jeffery, E.H.2    Wallig, M.A.3
  • 33
    • 0019954048 scopus 로고
    • Indole-3-carbinol and indole-3-acetonitrile influence on hepatic microsomal metabolism
    • [33] H.G. Shertzer, Indole-3-carbinol and indole-3-acetonitrile influence on hepatic microsomal metabolism, Toxicol. Appl. Pharmacol., 64 (1982) 353-361.
    • (1982) Toxicol. Appl. Pharmacol. , vol.64 , pp. 353-361
    • Shertzer, H.G.1
  • 34
    • 0025783861 scopus 로고
    • Chemoprotective and hepatic enzyme induction properties of indole and indenoindole antioxidants in rats
    • [34] H.G. Shertzer and M. Sainsbury, Chemoprotective and hepatic enzyme induction properties of indole and indenoindole antioxidants in rats, Food Chem. Toxicol., 29 (1991) 391-400.
    • (1991) Food Chem. Toxicol. , vol.29 , pp. 391-400
    • Shertzer, H.G.1    Sainsbury, M.2
  • 35
    • 0025811204 scopus 로고
    • Intrinsic acute toxicity and hepatic enzyme inducing properties of the chemoprotectants indole-3-carbinol and 5,10-dihydroindeno[1,2-b]indole in mice
    • [35] H.G. Shertzer and M. Sainsbury, Intrinsic acute toxicity and hepatic enzyme inducing properties of the chemoprotectants indole-3-carbinol and 5,10-dihydroindeno[1,2-b]indole in mice, Food Chem. Toxicol., 29 (1991) 237-242.
    • (1991) Food Chem. Toxicol. , vol.29 , pp. 237-242
    • Shertzer, H.G.1    Sainsbury, M.2
  • 37
    • 0020614363 scopus 로고
    • Protection by indole-3-carbinol against covalent binding of benzo[a]pyrene metabolites to mouse liver DNA and protein
    • [37] H.G. Shertzer, Protection by indole-3-carbinol against covalent binding of benzo[a]pyrene metabolites to mouse liver DNA and protein, Food Chem. Toxicol., 21 (1983) 31-35.
    • (1983) Food Chem. Toxicol. , vol.21 , pp. 31-35
    • Shertzer, H.G.1
  • 38
    • 0021342592 scopus 로고
    • Indole-3-carbinol protects against covalent binding of benzo[a]pyrene and N-nitrosodimethylamine metabolites to mouse liver macromolecules
    • [38] H.G. Shertzer, Indole-3-carbinol protects against covalent binding of benzo[a]pyrene and JV-nitrosodimethylamine metabolites to mouse liver macromolecules, Chem. Biol. Interact., 48 (1984) 81-90.
    • (1984) Chem. Biol. Interact. , vol.48 , pp. 81-90
    • Shertzer, H.G.1
  • 39
    • 0026731082 scopus 로고
    • Organ-selective induction of cytochrome P-450-dependent activities by indole-3-carbinol-derived products: Influence on covalent binding of benzo[a]pyrene to hepatic and pulmonary DNA in the rat
    • [39] J.-Y. Park and L.F. Bjeldanes, Organ-selective induction of cytochrome P-450-dependent activities by indole-3-carbinol-derived products: influence on covalent binding of benzo[a]pyrene to hepatic and pulmonary DNA in the rat, Chem. Biol. Interact., 83 (1992) 235-247.
    • (1992) Chem. Biol. Interact. , vol.83 , pp. 235-247
    • Park, J.-Y.1    Bjeldanes, L.F.2
  • 40
    • 0016803938 scopus 로고
    • Aryl hydrocarbon hydroxylase induction in rat tissues by naturally occurring indoles of cruciferous plants
    • [40] W.D. Loub, L.W. Wattenberg and D.W. Davis, Aryl hydrocarbon hydroxylase induction in rat tissues by naturally occurring indoles of cruciferous plants, J. Natl. Cancer Inst., 54 (1975) 985-988.
    • (1975) J. Natl. Cancer Inst. , vol.54 , pp. 985-988
    • Loub, W.D.1    Wattenberg, L.W.2    Davis, D.W.3
  • 41
    • 0021738060 scopus 로고
    • Effect of dietary indole-3-carbinol on intestinal and hepatic monooxygenase, glutathione S-transferase and epoxide hydrolase activities in the rat
    • [41] C.A. Bradfield and L.F. Bjeldanes, Effect of dietary indole-3-carbinol on intestinal and hepatic monooxygenase, glutathione S-transferase and epoxide hydrolase activities in the rat, Food Chem. Toxicol., 22 (1984) 977-982.
    • (1984) Food Chem. Toxicol. , vol.22 , pp. 977-982
    • Bradfield, C.A.1    Bjeldanes, L.F.2
  • 43
    • 0021979963 scopus 로고
    • The effects of dietary Brussels sprouts and Schizandra chinensis on the xenobiotic-metabolizing enzymes of the rat small intestine
    • [43] A.D. Salbe and L.F. Bjeldanes, The effects of dietary Brussels sprouts and Schizandra chinensis on the xenobiotic-metabolizing enzymes of the rat small intestine, Food Chem. Toxicol., 23 (1985) 57-65.
    • (1985) Food Chem. Toxicol. , vol.23 , pp. 57-65
    • Salbe, A.D.1    Bjeldanes, L.F.2
  • 44
    • 0020613857 scopus 로고
    • Effects of dietary cabbage, Brussels sprouts, Illicium verum, Schizandra chinensis and alfalfa on the benzoalpyrene metabolic system in mouse liver
    • [44] S. Hendrich and L.F. Bjeldanes, Effects of dietary cabbage, Brussels sprouts, Illicium verum, Schizandra chinensis and alfalfa on the benzo[alpyrene metabolic system in mouse liver, Food Chem. Toxicol., 21 (1983) 479-486.
    • (1983) Food Chem. Toxicol. , vol.21 , pp. 479-486
    • Hendrich, S.1    Bjeldanes, L.F.2
  • 46
    • 0020528001 scopus 로고
    • Effects of dietary broccoli and butylated hydroxanisole on liver-mediated metabolism of benzo[a]pyrene
    • [46] K.E. Aspry and L.F. Bjeldanes, Effects of dietary broccoli and butylated hydroxanisole on liver-mediated metabolism of benzo[a]pyrene, Food Chem. Toxicol., 21 (1983) 133-142.
    • (1983) Food Chem. Toxicol. , vol.21 , pp. 133-142
    • Aspry, K.E.1    Bjeldanes, L.F.2
  • 48
    • 0015096318 scopus 로고
    • Studies of polycyclic hydrocarbon hydroxylases of the intestine possibly related to cancer. Effect of diet on benzpyrene hydroxylase activity
    • [48] L.W. Wattenberg, Studies of polycyclic hydrocarbon hydroxylases of the intestine possibly related to cancer. Effect of diet on benzpyrene hydroxylase activity, Cancer, 28 (1971) 99-102.
    • (1971) Cancer , vol.28 , pp. 99-102
    • Wattenberg, L.W.1
  • 49
    • 0019831008 scopus 로고
    • α-Naphthylisothiocyanate induced alterations in hepatic drug metabolizing enzymes and liver morphology: Implications concerning anticarcinogenesis
    • [49] T.B. Leonard, J.A. Popp, M.E. Graichen and J.G. Dent, α-Naphthylisothiocyanate induced alterations in hepatic drug metabolizing enzymes and liver morphology: implications concerning anticarcinogenesis, Carcinogenesis, 2 (1981) 473-482.
    • (1981) Carcinogenesis , vol.2 , pp. 473-482
    • Leonard, T.B.1    Popp, J.A.2    Graichen, M.E.3    Dent, J.G.4
  • 50
    • 0019816528 scopus 로고
    • β-Naphthylisothiocyanate-induced alterations in hepatic drug metabolism and liver morphology
    • [50] T.B. Leonard, J.A. Popp, M.E. Graichen and J.G. Dent, β-Naphthylisothiocyanate-induced alterations in hepatic drug metabolism and liver morphology, Toxicol. Appl. Pharmacol., 60 (1981) 527-534.
    • (1981) Toxicol. Appl. Pharmacol. , vol.60 , pp. 527-534
    • Leonard, T.B.1    Popp, J.A.2    Graichen, M.E.3    Dent, J.G.4
  • 51
    • 0021020959 scopus 로고
    • 1 hepatocarcinoma inhibitor, and other indole analogs on the rainbow trout hepatic mixed function oxidase system
    • 1 hepatocarcinoma inhibitor, and other indole analogs on the rainbow trout hepatic mixed function oxidase system, Toxicol. Lett., 19 (1983) 133-138.
    • (1983) Toxicol. Lett. , vol.19 , pp. 133-138
    • Eisele, T.A.1    Bailey, G.S.2    Nixon, J.E.3
  • 53
    • 0027273265 scopus 로고
    • Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1 -(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice
    • [53] Z. Guo, T.J. Smith, E. Wang, K.I. Eklind, F.-L. Chung and C.S. Yang, Structure-activity relationships of arylalkyl isothiocyanates for the inhibition of 4-(methylnitrosamino)-1 -(3-pyridyl)-1-butanone metabolism and the modulation of xenobiotic-metabolizing enzymes in rats and mice, Carcinogenesis, 14 (1993) 1167-1173.
    • (1993) Carcinogenesis , vol.14 , pp. 1167-1173
    • Guo, Z.1    Smith, T.J.2    Wang, E.3    Eklind, K.I.4    Chung, F.-L.5    Yang, C.S.6
  • 54
    • 0027055359 scopus 로고
    • Effects of phenethyl isothiocyanate, a carcinogenesis inhibitor, on xenobiotioc-metabolizing enzymes and nitrosamine metabolism in rats
    • [54] Z. Guo, T.J. Smith, E. Wang, N. Sadrieh, Q. Ma, P.E. Thomas and C.S. Yang, Effects of phenethyl isothiocyanate, a carcinogenesis inhibitor, on xenobiotioc-metabolizing enzymes and nitrosamine metabolism in rats, Carcinogenesis, 13 (1992) 2205-2210.
    • (1992) Carcinogenesis , vol.13 , pp. 2205-2210
    • Guo, Z.1    Smith, T.J.2    Wang, E.3    Sadrieh, N.4    Ma, Q.5    Thomas, P.E.6    Yang, C.S.7
  • 55
    • 0027362840 scopus 로고
    • Experimental down-regulation of intermediate biomarkers of carcinogenesis in mouse mammary epithelial cells
    • [55] A. Suto, H.L. Bradlow, G.Y.C. Wong, M.P. Osborne and N.T. Telang, Experimental down-regulation of intermediate biomarkers of carcinogenesis in mouse mammary epithelial cells, Breast Cancer Res. Treat., 27 (1993) 193-202.
    • (1993) Breast Cancer Res. Treat. , vol.27 , pp. 193-202
    • Suto, A.1    Bradlow, H.L.2    Wong, G.Y.C.3    Osborne, M.P.4    Telang, N.T.5
  • 56
    • 0026735810 scopus 로고
    • Persistent estrogen responsiveness of ras oncogene-transformed mouse mammary epithelial cells
    • [56] A. Suto, H.L. Bradlow, G.Y. Wong, M.P. Osborne and N.T. Telang, Persistent estrogen responsiveness of ras oncogene-transformed mouse mammary epithelial cells, Steroids, 57 (1992) 262-268.
    • (1992) Steroids , vol.57 , pp. 262-268
    • Suto, A.1    Bradlow, H.L.2    Wong, G.Y.3    Osborne, M.P.4    Telang, N.T.5
  • 57
    • 0028088840 scopus 로고
    • Selective responsiveness of human breast cancer cells to indole-3-carbinol, a chemopreventive agent
    • [57] R.K. Tiwari, L. Guo, H.L. Bradlow, N.T. Telang and M.P. Osborne, Selective responsiveness of human breast cancer cells to indole-3-carbinol, a chemopreventive agent, J. Natl. Cancer Inst., 86 (1994) 126-131.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 126-131
    • Tiwari, R.K.1    Guo, L.2    Bradlow, H.L.3    Telang, N.T.4    Osborne, M.P.5
  • 58
    • 0028040949 scopus 로고
    • Alterations in estradiol metabolism in MCF-7 cells induced by treatment with indole-3-carbinol and related compounds
    • [58] T. Niwa, G. Swaneck and H.L. Bradlow, Alterations in estradiol metabolism in MCF-7 cells induced by treatment with indole-3-carbinol and related compounds, Steroids, 59 (1994) 523-527.
    • (1994) Steroids , vol.59 , pp. 523-527
    • Niwa, T.1    Swaneck, G.2    Bradlow, H.L.3
  • 59
    • 0028281779 scopus 로고
    • Chemoprevention of spontaneous endometrial cancer in female Donryu rats by dietary indole-3-carbinol
    • [59] T. Kojima, T. Tanaka and H. Mon, Chemoprevention of spontaneous endometrial cancer in female Donryu rats by dietary indole-3-carbinol, Cancer Res., 54 (1994) 1446-1449.
    • (1994) Cancer Res. , vol.54 , pp. 1446-1449
    • Kojima, T.1    Tanaka, T.2    Mon, H.3
  • 60
    • 0026794317 scopus 로고
    • The anti-carcinogenic plant compound indole-3-carbinol differentially modulates P450-mediated steroid hydroxylase activities in mice
    • [60] W.S. Baldwin and G.A. Le Blanc, The anti-carcinogenic plant compound indole-3-carbinol differentially modulates P450-mediated steroid hydroxylase activities in mice, Chem. Biol. Interact., 83 (1992) 155-169.
    • (1992) Chem. Biol. Interact. , vol.83 , pp. 155-169
    • Baldwin, W.S.1    Le Blanc, G.A.2
  • 61
    • 0025776365 scopus 로고
    • Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice
    • [61] H.L. Bradlow, J.J. Michnovicz, N.T. Telang and M.P. Osborne, Effects of dietary indole-3-carbinol on estradiol metabolism and spontaneous mammary tumors in mice, Carcinogenesis, 12 (1991) 1571-1574.
    • (1991) Carcinogenesis , vol.12 , pp. 1571-1574
    • Bradlow, H.L.1    Michnovicz, J.J.2    Telang, N.T.3    Osborne, M.P.4
  • 63
    • 0028301879 scopus 로고
    • Catechol estrogen production in rat microsomes after treatment with indole-3-carbinol, ascorbigen, or β-naphthaflavone: A comparison of stable isotope dilution gas chromatography-mass spectrometry and radiometric methods
    • [63] D.W. Sepkovic, H.L. Bradlow, J.J. Michnovicz, S. Murtezani, I. Levy and M.P. Osborne, Catechol estrogen production in rat microsomes after treatment with indole-3-carbinol, ascorbigen, or β-naphthaflavone: a comparison of stable isotope dilution gas chromatography-mass spectrometry and radiometric methods, Steroids, 59 (1994) 318-323.
    • (1994) Steroids , vol.59 , pp. 318-323
    • Sepkovic, D.W.1    Bradlow, H.L.2    Michnovicz, J.J.3    Murtezani, S.4    Levy, I.5    Osborne, M.P.6
  • 65
    • 0024506334 scopus 로고
    • Modulating effects of naturally occurring indoles on SCE induction depend largely on the type of mutagen
    • [65] W.M.F. Jongen, R.J. Topp, K.J.H. Wienk, and E.C. Homan, Modulating effects of naturally occurring indoles on SCE induction depend largely on the type of mutagen, Mutat. Res., 222 (1989) 263-269.
    • (1989) Mutat. Res. , vol.222 , pp. 263-269
    • Jongen, W.M.F.1    Topp, R.J.2    Wienk, K.J.H.3    Homan, E.C.4
  • 66
    • 0025209985 scopus 로고
    • Effect of phenethyl isothiocyanate on microsomal N-nitrosodimethylamine metabolism and other monooxygenase activities
    • [66] H. Ishizaki, J.F. Brady, S.M. Ning and C.S. Yang, Effect of phenethyl isothiocyanate on microsomal N-nitrosodimethylamine metabolism and other monooxygenase activities, Xenobiotica, 20 (1990) 255-264.
    • (1990) Xenobiotica , vol.20 , pp. 255-264
    • Ishizaki, H.1    Brady, J.F.2    Ning, S.M.3    Yang, C.S.4
  • 67
    • 0028854642 scopus 로고
    • Regulation of hepatic cytochrome P4501A by indole-3-carbinol: Transient induction with continuous feeding in rainbow trout
    • [67] N. Takahashi, R.H. Dashwood, L.F. Bjeldanes, G.S. Bailey and D.E. Williams, Regulation of hepatic cytochrome P4501A by indole-3-carbinol: transient induction with continuous feeding in rainbow trout, Food Chem. Toxicol., 33 (1995) 111-120.
    • (1995) Food Chem. Toxicol. , vol.33 , pp. 111-120
    • Takahashi, N.1    Dashwood, R.H.2    Bjeldanes, L.F.3    Bailey, G.S.4    Williams, D.E.5
  • 68
    • 0027325487 scopus 로고
    • Mechanisms of inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation in mouse by dietary phenethyl isothiocyanate
    • [68] T.J. Smith, Z. Guo, C. Li, S.M. Ning, P.E. Thomas and C.S. Yang, Mechanisms of inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone bioactivation in mouse by dietary phenethyl isothiocyanate, Cancer Res., 53 (1993) 3276-3282.
    • (1993) Cancer Res. , vol.53 , pp. 3276-3282
    • Smith, T.J.1    Guo, Z.2    Li, C.3    Ning, S.M.4    Thomas, P.E.5    Yang, C.S.6
  • 70
    • 0029900928 scopus 로고    scopus 로고
    • Protection by green tea, black tea, and indole-3-carbinol against 2-amino-3-methylimidazo[4,5-/]quinoline-in-duced DNA adducts and colonic aberrant crypts in the F344 rat
    • [70] M. Xu, A.C. Bailey, J.F. Hernaez, C.R. Taoka, H.A.J. Schut and R.H. Dashwood, Protection by green tea, black tea, and indole-3-carbinol against 2-amino-3-methylimidazo[4,5-/]quinoline-in-duced DNA adducts and colonic aberrant crypts in the F344 rat, Carcinogenesis, 17 (1996) 1429-1434.
    • (1996) Carcinogenesis , vol.17 , pp. 1429-1434
    • Xu, M.1    Bailey, A.C.2    Hernaez, J.F.3    Taoka, C.R.4    Schut, H.A.J.5    Dashwood, R.H.6
  • 71
    • 0026668771 scopus 로고
    • Effects of indole-3-carbinol on biotransformation enzymes in the rat: In vivo changes in liver and small intestinal mucosa in comparison with primary hepatocyte cultures
    • [71] H.M. Wortelboer, E.C.M. van der Linden, C.A. de Kruif, J. Noordhoek, B.J. Blaauboer, P.J. van Bladeren and H.E. Falke, Effects of indole-3-carbinol on biotransformation enzymes in the rat: in vivo changes in liver and small intestinal mucosa in comparison with primary hepatocyte cultures, Food Chem. Toxicol., 30 (1992) 589-599.
    • (1992) Food Chem. Toxicol. , vol.30 , pp. 589-599
    • Wortelboer, H.M.1    Van Der Linden, E.C.M.2    De Kruif, C.A.3    Noordhoek, J.4    Blaauboer, B.J.5    Van Bladeren, P.J.6    Falke, H.E.7
  • 72
    • 0029959032 scopus 로고    scopus 로고
    • Indole-3-carbinol and dundolylmethane as aryl hydrocarbon (Ah) receptor agonists and antagonists in T47D human breast cancer cells
    • [72] I. Chen, S. Safe and L. Bjeldanes, Indole-3-carbinol and dundolylmethane as aryl hydrocarbon (Ah) receptor agonists and antagonists in T47D human breast cancer cells, Biochem. Pharmacol., 51 (1996) 1069-1076.
    • (1996) Biochem. Pharmacol. , vol.51 , pp. 1069-1076
    • Chen, I.1    Safe, S.2    Bjeldanes, L.3
  • 73
    • 0023215434 scopus 로고
    • Differential induction of mixed-function oxidase (MFO) activity in rat liver and intestine by diets containing processed cabbage: Correlation with cabbage levels of glucosinolates and glucosinolate hydrolysis products
    • [73] R.E. McDanell, A.E.M. McLean, A.B. Hanley, R.K. Heany and G.R. Fenwick, Differential induction of mixed-function oxidase (MFO) activity in rat liver and intestine by diets containing processed cabbage: correlation with cabbage levels of glucosinolates and glucosinolate hydrolysis products, Food Chem. Toxicol., 25 (1987) 363-368.
    • (1987) Food Chem. Toxicol. , vol.25 , pp. 363-368
    • McDanell, R.E.1    McLean, A.E.M.2    Hanley, A.B.3    Heany, R.K.4    Fenwick, G.R.5
  • 74
    • 0026505775 scopus 로고
    • Acid reaction products of indole-3-carbinol and their effects on cytochrome P450 and phase II enzymes in rat and monkey hepatocytes
    • [74] H.M. Wortelboer, C.A. de Kruif, A.A.J. van Iersel, H.E. Falke, J. Noordhoek and B.J. Blaauboer, Acid reaction products of indole-3-carbinol and their effects on cytochrome P450 and phase II enzymes in rat and monkey hepatocytes, Biochem. Pharmacol., 43 (1992) 1439-1447.
    • (1992) Biochem. Pharmacol. , vol.43 , pp. 1439-1447
    • Wortelboer, H.M.1    De Kruif, C.A.2    Van Iersel, A.A.J.3    Falke, H.E.4    Noordhoek, J.5    Blaauboer, B.J.6
  • 75
    • 0023179020 scopus 로고
    • Structure-activity relationships of dietary indoles: A proposed mechanism of action as modifiers of xenobiotic metabolism
    • [75] C.A. Bradfield and L.F. Bjeldanes, Structure-activity relationships of dietary indoles: a proposed mechanism of action as modifiers of xenobiotic metabolism, J. Toxicol. Environ. Health, 21 (1987) 311-323.
    • (1987) J. Toxicol. Environ. Health , vol.21 , pp. 311-323
    • Bradfield, C.A.1    Bjeldanes, L.F.2
  • 76
    • 0026046412 scopus 로고
    • Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: Comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin
    • [76] L.F. Bjeldanes, J.-Y. Kim, K.R. Grose, J.C. Bartholomew and C.A. Bradfield, Aromatic hydrocarbon responsiveness-receptor agonists generated from indole-3-carbinol in vitro and in vivo: comparisons with 2,3,7,8-tetrachlorodibenzo-p-dioxin, Proc. Natl. Acad. Sci. USA, 88 (1991) 9543-9547.
    • (1991) Proc. Natl. Acad. Sci. USA , vol.88 , pp. 9543-9547
    • Bjeldanes, L.F.1    Kim, J.-Y.2    Grose, K.R.3    Bartholomew, J.C.4    Bradfield, C.A.5
  • 78
    • 0028109671 scopus 로고
    • Indolo[3,2-b]carbazole: A dietary-derived factor that exhibits both antiestrogenic and estrogenic activity
    • [78] H. Liu, M. Wormke, S.H. Safe and L.F. Bjeldanes, Indolo[3,2-b]carbazole: a dietary-derived factor that exhibits both antiestrogenic and estrogenic activity, J. Natl. Cancer Inst., 86 (1994) 1758-1765.
    • (1994) J. Natl. Cancer Inst. , vol.86 , pp. 1758-1765
    • Liu, H.1    Wormke, M.2    Safe, S.H.3    Bjeldanes, L.F.4
  • 79
    • 0024400533 scopus 로고
    • The effect of feeding brassica vegetables and intact glucosinolates on mixed-function-oxidase activity in the livers and intestines of rats
    • [79] R. McDanell, A.E.M. McLean, A.B. Hanley, R.K. Heaney and G.R. Fenwick, The effect of feeding brassica vegetables and intact glucosinolates on mixed-function-oxidase activity in the livers and intestines of rats, Food Chem. Toxicol., 27 (1989) 289-293.
    • (1989) Food Chem. Toxicol. , vol.27 , pp. 289-293
    • McDanell, R.1    McLean, A.E.M.2    Hanley, A.B.3    Heaney, R.K.4    Fenwick, G.R.5
  • 83
    • 0025168280 scopus 로고
    • Induction of cytochrome P4SOIA1 in rat colon and liver by indole-3-carbinol and 5,6-benzoflavone
    • [83] O. Vang, M.B. Jensen and H. Autrup, Induction of cytochrome P4SOIA1 in rat colon and liver by indole-3-carbinol and 5,6-benzoflavone, Carcinogenesis, 11 (1990) 1259-1263.
    • (1990) Carcinogenesis , vol.11 , pp. 1259-1263
    • Vang, O.1    Jensen, M.B.2    Autrup, H.3
  • 84
    • 0028033842 scopus 로고
    • Distinct forms of hepatic androgen 6β-hydroxylase induced in the rat by indole-3-carbinol and pregnenolone carbonitrile
    • [84] P.H. Jellinck, A.-M. Newcombe, P.G. Forkert and C.P. Martucci, Distinct forms of hepatic androgen 6β-hydroxylase induced in the rat by indole-3-carbinol and pregnenolone carbonitrile, J. Steroid Biochem. Molec. Biol., 51 (1994) 219-225.
    • (1994) J. Steroid Biochem. Molec. Biol. , vol.51 , pp. 219-225
    • Jellinck, P.H.1    Newcombe, A.-M.2    Forkert, P.G.3    Martucci, C.P.4
  • 85
    • 0026034079 scopus 로고
    • Induction of cytochrome P-4501A1, IA2, IIB1, IIB2 and IIE1 by broccoli in rat liver and colon
    • [85] O. Vang, H. Jensen and H. Autrup, Induction of cytochrome P-4501A1, IA2, IIB1, IIB2 and IIE1 by broccoli in rat liver and colon, Chem. Biol. Interact., 78 (1991) 85-96.
    • (1991) Chem. Biol. Interact. , vol.78 , pp. 85-96
    • Vang, O.1    Jensen, H.2    Autrup, H.3
  • 86
    • 0011393295 scopus 로고
    • Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and inhibition by phenethyl isothiocyanate (PEITC)
    • [86] T.J. Smith, Z. Guo, F.P. Guengerich and C.S. Yang, Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and inhibition by phenethyl isothiocyanate (PEITC), Proc. Am. Assoc. Cancer Res., 36 (1995) 153.
    • (1995) Proc. Am. Assoc. Cancer Res. , vol.36 , pp. 153
    • Smith, T.J.1    Guo, Z.2    Guengerich, F.P.3    Yang, C.S.4
  • 87
    • 0029986896 scopus 로고    scopus 로고
    • Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate
    • [87] T.J. Smith, Z. Guo, F.P. Guengerich and C.S. Yang, Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by human cytochrome P450 1A2 and its inhibition by phenethyl isothiocyanate, Carcinogenesis, 17 (1996) 809-813.
    • (1996) Carcinogenesis , vol.17 , pp. 809-813
    • Smith, T.J.1    Guo, Z.2    Guengerich, F.P.3    Yang, C.S.4
  • 89
    • 0029879994 scopus 로고    scopus 로고
    • CYP2EI-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane
    • [89] S. Barcelo, J.M. Gardiner, A. Gescher and J.K. Chipman, CYP2EI-mediated mechanism of anti-genotoxicity of the broccoli constituent sulforaphane, Carcinogenesis, 17 (1996) 277-282.
    • (1996) Carcinogenesis , vol.17 , pp. 277-282
    • Barcelo, S.1    Gardiner, J.M.2    Gescher, A.3    Chipman, J.K.4
  • 90
    • 0029901681 scopus 로고    scopus 로고
    • Effect of oltipraz, α-tocopherol, β-carotene and phenethylisothiocyanate on rat oesophageal, gastric, colonic and hepatic glutathione, glutathione S-transferase and peroxidase
    • [90] E.M.M. Van Lieshout, W.H.M. Peters and J.B.M.J. Jansen, Effect of oltipraz, α-tocopherol, β-carotene and phenethylisothiocyanate on rat oesophageal, gastric, colonic and hepatic glutathione, glutathione S-transferase and peroxidase, Carcinogenesis, 17 (1996) 1439-1445.
    • (1996) Carcinogenesis , vol.17 , pp. 1439-1445
    • Van Lieshout, E.M.M.1    Peters, W.H.M.2    Jansen, J.B.M.J.3
  • 91
    • 0019462080 scopus 로고
    • Enhancement of glutathione S-transferase activity of the mouse forestomach by inhibitors of benzo[a]pyrene-induced neoplasia of the forestomach
    • [91] V.L. Sparnins and L.W. Wattenberg, Enhancement of glutathione S-transferase activity of the mouse forestomach by inhibitors of benzo[a]pyrene-induced neoplasia of the forestomach, J. Natl. Cancer Inst., 66 (1981) 769-771.
    • (1981) J. Natl. Cancer Inst. , vol.66 , pp. 769-771
    • Sparnins, V.L.1    Wattenberg, L.W.2
  • 92
    • 0020052039 scopus 로고
    • Enhancement of glutathione S-transferase activity of the esophagus by phenols, lactones, and benzyl isothiocyanate
    • [92] V.L. Sparnins, J. Chuan and L.W. Wattenberg, Enhancement of glutathione S-transferase activity of the esophagus by phenols, lactones, and benzyl isothiocyanate, Cancer Res., 42 (1982) 1205-1207.
    • (1982) Cancer Res. , vol.42 , pp. 1205-1207
    • Sparnins, V.L.1    Chuan, J.2    Wattenberg, L.W.3
  • 93
    • 0020076847 scopus 로고
    • Glutathione S-transferase activity: Enhancement by compounds inhibiting chemical carcinogenesis and by dietary constituents
    • [93] V.L. Sparnins, P.L. Venegas and L.W. Wattenberg, Glutathione S-transferase activity: enhancement by compounds inhibiting chemical carcinogenesis and by dietary constituents, J. Natl. Cancer Inst., 68 (1982) 493-496.
    • (1982) J. Natl. Cancer Inst. , vol.68 , pp. 493-496
    • Sparnins, V.L.1    Venegas, P.L.2    Wattenberg, L.W.3
  • 94
    • 0022356047 scopus 로고
    • Effects of disulfiram, diethyldithiocarbamate, bisethylxanthogen, and benzyl isothiocyanate on glutathione transferase activities in mouse organs
    • [94] A.M. Benson and P.B. Barretto, Effects of disulfiram, diethyldithiocarbamate, bisethylxanthogen, and benzyl isothiocyanate on glutathione transferase activities in mouse organs, Cancer Res., 45 (1985) 4219-4223.
    • (1985) Cancer Res. , vol.45 , pp. 4219-4223
    • Benson, A.M.1    Barretto, P.B.2
  • 95
    • 0026577605 scopus 로고
    • A major inducer of anticarcinogenic protective enzymes from broccoli: Isolation and elucidation of structure
    • [95] Y. Zhang, P. Talalay, C.-G. Cho and G.H. Posner, A major inducer of anticarcinogenic protective enzymes from broccoli: isolation and elucidation of structure, Proc. Natl. Acad. Sci. USA, 89 (1992) 2399-2403.
    • (1992) Proc. Natl. Acad. Sci. USA , vol.89 , pp. 2399-2403
    • Zhang, Y.1    Talalay, P.2    Cho, C.-G.3    Posner, G.H.4
  • 96
    • 0025369383 scopus 로고
    • Glutathione S-transferase subunit induction patterns of Brussels sprouts, allyl isothiocyanate and goitrin in rat liver and small intestinal mucosa: A new approach for the identification of inducing xenobiotics
    • [96] J.J.P. Bogaards, B. van Ommen, H.E. Falke, M.I. Willems and P.J. van Bladeren, Glutathione S-transferase subunit induction patterns of Brussels sprouts, allyl isothiocyanate and goitrin in rat liver and small intestinal mucosa: a new approach for the identification of inducing xenobiotics, Food Chem. Toxicol., 28 (1990) 81-88.
    • (1990) Food Chem. Toxicol. , vol.28 , pp. 81-88
    • Bogaards, J.J.P.1    Van Ommen, B.2    Falke, H.E.3    Willems, M.I.4    Van Bladeren, P.J.5
  • 97
    • 0024386419 scopus 로고
    • Modulating effects of indoles on benzo[a]pyrene-induced sister chromatid exchanges and the balance between drug-metabolizing enzymes
    • [97] W.M.F. Jongen, R.J. Topp, P.J. van Bladeren, J. Lapre, K.J.H. Wienk and R. Leenen, Modulating effects of indoles on benzo[a]pyrene-induced sister chromatid exchanges and the balance between drug-metabolizing enzymes, Toxic. in vitro, 3 (1989) 207-213.
    • (1989) Toxic. in Vitro , vol.3 , pp. 207-213
    • Jongen, W.M.F.1    Topp, R.J.2    Van Bladeren, P.J.3    Lapre, J.4    Wienk, K.J.H.5    Leenen, R.6
  • 99
    • 0027433751 scopus 로고
    • Induction of rat hepatic and intestinal glutathione S-transferases and gluthathione by dietary naturally occurring anticarcinogens
    • [99] W.A. Nijhoff, G.M. Groen and W.H.M. Peters, Induction of rat hepatic and intestinal glutathione S-transferases and gluthathione by dietary naturally occurring anticarcinogens, Int. J. Oncol., 3 (1993) 1131-1139.
    • (1993) Int. J. Oncol. , vol.3 , pp. 1131-1139
    • Nijhoff, W.A.1    Groen, G.M.2    Peters, W.H.M.3
  • 100
    • 0027228420 scopus 로고
    • Alterations of the hepatic xenobiotic-metabolizing enzymes by a glucosinolate-rich diet in germ-free rats: Influence of a pre-induction with phenobarbital
    • [100] S. Rabot, L. Nugon-Baudon and O. Szylit, Alterations of the hepatic xenobiotic-metabolizing enzymes by a glucosinolate-rich diet in germ-free rats: influence of a pre-induction with phenobarbital, Br. J. Nutr., 70 (1993) 347-354.
    • (1993) Br. J. Nutr. , vol.70 , pp. 347-354
    • Rabot, S.1    Nugon-Baudon, L.2    Szylit, O.3
  • 101
    • 0022608501 scopus 로고
    • Induction of DT-diaphorase by anticarcinogenic sulfur compounds in mice
    • [101] A.M. Benson, P.B. Barretto and J.S. Stanley, Induction of DT-diaphorase by anticarcinogenic sulfur compounds in mice, J. Natl. Cancer Inst., 76 (1986) 467-473.
    • (1986) J. Natl. Cancer Inst. , vol.76 , pp. 467-473
    • Benson, A.M.1    Barretto, P.B.2    Stanley, J.S.3
  • 102
    • 0028127980 scopus 로고
    • Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: Correlation between structure and potency as inducers of anticarcinogenic detoxification enzymes
    • [102] G.H. Posner, C.-G. Cho, J.V. Green, Y. Zhang and P. Talalay, Design and synthesis of bifunctional isothiocyanate analogs of sulforaphane: correlation between structure and potency as inducers of anticarcinogenic detoxification enzymes, J. Med. Chem., 37 (1994) 170-176.
    • (1994) J. Med. Chem. , vol.37 , pp. 170-176
    • Posner, G.H.1    Cho, C.-G.2    Green, J.V.3    Zhang, Y.4    Talalay, P.5
  • 103
    • 0029053409 scopus 로고
    • Dietary glucosinolates as blocking agents against carcinogenesis: Glucosinolate breakdown products assessed by induction of quinone reductase activity in murine hepa1c1c7 cells
    • [103] N. Tawfiq, R.K. Heaney, J.A. Plumb, G.R. Fenwick, S.R.R. Musk and G. Williamson, Dietary glucosinolates as blocking agents against carcinogenesis: glucosinolate breakdown products assessed by induction of quinone reductase activity in murine hepa1c1c7 cells, Carcinogenesis, 16 (1995) 1191-1194.
    • (1995) Carcinogenesis , vol.16 , pp. 1191-1194
    • Tawfiq, N.1    Heaney, R.K.2    Plumb, J.A.3    Fenwick, G.R.4    Musk, S.R.R.5    Williamson, G.6
  • 104
    • 0011392509 scopus 로고
    • Effects of food components on phase 1 (activating), phase 2 (conjugating) and antioxidant enzymes
    • H. Kozlowska, J. Fornal and Z. Zduticzyk (Eds.), Dietary Cancer Prevention, Centre for Agrotechnology and Veterinary Sciences, Olszytn, Poland
    • [104] G. Williamson, Effects of food components on phase 1 (activating), phase 2 (conjugating) and antioxidant enzymes, in: H. Kozlowska, J. Fornal and Z. Zduticzyk (Eds.), Proc. of the Int. Conference Euro Food Tox IV 'Bioactive substances in food of plant origin', Vol. 2 Dietary Cancer Prevention, Centre for Agrotechnology and Veterinary Sciences, Olszytn, Poland 1994, pp. 360-370.
    • (1994) Proc. of the Int. Conference Euro Food Tox IV 'Bioactive Substances in Food of Plant Origin' , vol.2 , pp. 360-370
    • Williamson, G.1
  • 105
    • 0028849168 scopus 로고
    • Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29
    • [105] S.R.R. Musk, P. Stephenson, T.K. Smith, P. Stening, D. Fyfe and I.T. Johnson, Selective toxicity of compounds naturally present in food toward the transformed phenotype of human colorectal cell line HT29, Nutr. Cancer, 24 (1995) 289-298.
    • (1995) Nutr. Cancer , vol.24 , pp. 289-298
    • Musk, S.R.R.1    Stephenson, P.2    Smith, T.K.3    Stening, P.4    Fyfe, D.5    Johnson, I.T.6
  • 106
    • 0029983558 scopus 로고    scopus 로고
    • The essential role of the functional group in alkyl isothiocyanates for inhibition of tobacco nitrosamine-induced lung tumorigenesis
    • [106] D. Jiao, T.J. Smith, S. Kim, C.S. Yang, D. Desai, S Amin and F.-L. Chung, The essential role of the functional group in alkyl isothiocyanates for inhibition of tobacco nitrosamine-induced lung tumorigenesis, Carcinogenesis, 17 (1996) 755-759.
    • (1996) Carcinogenesis , vol.17 , pp. 755-759
    • Jiao, D.1    Smith, T.J.2    Kim, S.3    Yang, C.S.4    Desai, D.5    Amin, S.6    Chung, F.-L.7
  • 107
    • 0025806929 scopus 로고
    • Effect of phenethyl isothiocyanate on the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured rat lung tissue
    • [107] K. Doerr-O'Rourke, N. Trushin, S.S. Hecht and G.D. Stoner, Effect of phenethyl isothiocyanate on the metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone by cultured rat lung tissue, Carcinogenesis, 12 (1991) 1029-1034.
    • (1991) Carcinogenesis , vol.12 , pp. 1029-1034
    • Doerr-O'Rourke, K.1    Trushin, N.2    Hecht, S.S.3    Stoner, G.D.4
  • 108
    • 0025736982 scopus 로고
    • Effect of phenethyl isothiocyanate on the metabolism of tobacco-specific nitrosamines by cultured rat oral tissue
    • [108] S.E. Murphy, R. Heiblum, P.G. King, D. Bowman, W.J. Davis and G.D. Stoner, Effect of phenethyl isothiocyanate on the metabolism of tobacco-specific nitrosamines by cultured rat oral tissue, Carcinogenesis, 12 (1991) 957-961.
    • (1991) Carcinogenesis , vol.12 , pp. 957-961
    • Murphy, S.E.1    Heiblum, R.2    King, P.G.3    Bowman, D.4    Davis, W.J.5    Stoner, G.D.6
  • 109
    • 0025133114 scopus 로고
    • Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates
    • [109] T.J. Smith, Z. Guo, P.E. Thomas, F.-L. Chung, M.A. Morse, K.I. Elkind, and C.S. Yang, Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in mouse lung microsomes and its inhibition by isothiocyanates, Cancer Res., 50 (1990) 6817-6822.
    • (1990) Cancer Res. , vol.50 , pp. 6817-6822
    • Smith, T.J.1    Guo, Z.2    Thomas, P.E.3    Chung, F.-L.4    Morse, M.A.5    Elkind, K.I.6    Yang, C.S.7
  • 110
    • 0026425564 scopus 로고
    • Metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone as measured by DNA alkyiation in vitro and its inhibition by isothiocyanates
    • [110] Z. Guo, T.J. Smith, P.E. Thomas and C.S. Yang, Metabolic activation of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone as measured by DNA alkyiation in vitro and its inhibition by isothiocyanates, Cancer Res., 51 (1991) 4798-4803.
    • (1991) Cancer Res. , vol.51 , pp. 4798-4803
    • Guo, Z.1    Smith, T.J.2    Thomas, P.E.3    Yang, C.S.4
  • 111
    • 0025937347 scopus 로고
    • Inhibition of tobacco-specific nitrosamine 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK) tumorigenesis with aromatic isothiocyanates
    • [111] M.A. Morse, K.I. Eklind, S.S. Hecht and F.-L. Chung, inhibition of tobacco-specific nitrosamine 4-(N-nitrosomethylamino)-1-(3-pyridyl)-1-butanone (NNK) tumorigenesis with aromatic isothiocyanates, IARC Sci. Publ., 105 (1991) 529-534.
    • (1991) IARC Sci. Publ. , vol.105 , pp. 529-534
    • Morse, M.A.1    Eklind, K.I.2    Hecht, S.S.3    Chung, F.-L.4
  • 112
    • 0024360557 scopus 로고
    • 6-methylguanine formation, and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung
    • 6-methylguanine formation, and metabolism of the tobacco-specific nitrosamine 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in A/J mouse lung, Cancer Res., 49 (1989) 2894-2897.
    • (1989) Cancer Res. , vol.49 , pp. 2894-2897
    • Morse, M.A.1    Amin, S.G.2    Hecht, S.S.3    Chung, F.-L.4
  • 113
    • 0025809376 scopus 로고
    • Structure-activity relationships for inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice
    • [113] M.A. Morse, K.I. Eklind, S.S. Hecht, K.G. Jordan, C-I. Choi, D.H. Desai, S.G. Amin, and F.L. Chung, Structure-activity relationships for inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone lung tumorigenesis by arylalkyl isothiocyanates in A/J mice, Cancer Res., 51 (1991) 1846-1850.
    • (1991) Cancer Res. , vol.51 , pp. 1846-1850
    • Morse, M.A.1    Eklind, K.I.2    Hecht, S.S.3    Jordan, K.G.4    Choi, C.-I.5    Desai, D.H.6    Amin, S.G.7    Chung, F.L.8
  • 114
    • 0024589128 scopus 로고
    • Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation and tumorigenicity in the lung of F344 rats by dietary phenethyl isothiocyanate
    • [114] M.A. Morse, C.-X. Wang, G.D. Stoner, S. Mandal, P.B. Conran, S.G. Amin, S.S. Hecht, and F.-L. Chung, Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced DNA adduct formation and tumorigenicity in the lung of F344 rats by dietary phenethyl isothiocyanate, Cancer Res., 49 (1989) 549-553.
    • (1989) Cancer Res. , vol.49 , pp. 549-553
    • Morse, M.A.1    Wang, C.-X.2    Stoner, G.D.3    Mandal, S.4    Conran, P.B.5    Amin, S.G.6    Hecht, S.S.7    Chung, F.-L.8
  • 115
    • 0029812570 scopus 로고    scopus 로고
    • Complete inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced rat lung tumorigenesis and favorable modification of biomarkers by phenethyl isothiocyanate
    • [115] S.S. Hecht, N. Trushin, J. Rigotty, S.G. Carmella, A. Borukhova, S. Akerkar and A. Rivenson, Complete inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced rat lung tumorigenesis and favorable modification of biomarkers by phenethyl isothiocyanate, Cancer Epidemiol. Biomarkers Prev., 5 (1996) 645-652.
    • (1996) Cancer Epidemiol. Biomarkers Prev. , vol.5 , pp. 645-652
    • Hecht, S.S.1    Trushin, N.2    Rigotty, J.3    Carmella, S.G.4    Borukhova, A.5    Akerkar, S.6    Rivenson, A.7
  • 116
    • 0028785916 scopus 로고
    • Effects of phenethyl isothiocyanate on the tissue distribution of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and metabolites in F344 rats
    • [116] M.E. Staretz and S.S. Hecht, Effects of phenethyl isothiocyanate on the tissue distribution of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and metabolites in F344 rats, Cancer Res., 55 (1995) 5580-5588.
    • (1995) Cancer Res. , vol.55 , pp. 5580-5588
    • Staretz, M.E.1    Hecht, S.S.2
  • 117
    • 0029145042 scopus 로고
    • Intestinal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rats: Sex-difference, inducibility and inhibition by phenethylisothiocyanate
    • [117] J. Schulze, A. Malone and E. Richter, Intestinal metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone in rats: sex-difference, inducibility and inhibition by phenethylisothiocyanate, Carcinogenesis, 16 (1995) 1733-1740.
    • (1995) Carcinogenesis , vol.16 , pp. 1733-1740
    • Schulze, J.1    Malone, A.2    Richter, E.3
  • 118
    • 0011443819 scopus 로고
    • Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolic activation by phenethyl isothiocyanate in rats and primates as assessed by biomarkers
    • [118] S.S. Hecht, N. Trushin, S.G. Carmella, S. Akerkar, J. Rigotty and L.M. Anderson, Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone metabolic activation by phenethyl isothiocyanate in rats and primates as assessed by biomarkers, Proc. Am. Assoc. Cancer Res., 36 (1995) 593.
    • (1995) Proc. Am. Assoc. Cancer Res. , vol.36 , pp. 593
    • Hecht, S.S.1    Trushin, N.2    Carmella, S.G.3    Akerkar, S.4    Rigotty, J.5    Anderson, L.M.6
  • 119
    • 0027318421 scopus 로고
    • Inhibition by phenylethyl and phenylhexyl isothiocyanate of metabolism of and DNA methylation by N-nitrosomethylamylamine in rats
    • [119] Q. Huang, T.A. Lawson, F.-L. Chung, C.R. Morris and S.S. Mervish, Inhibition by phenylethyl and phenylhexyl isothiocyanate of metabolism of and DNA methylation by N-nitrosomethylamylamine in rats, Carcinogenesis, 14 (1993) 749-754.
    • (1993) Carcinogenesis , vol.14 , pp. 749-754
    • Huang, Q.1    Lawson, T.A.2    Chung, F.-L.3    Morris, C.R.4    Mervish, S.S.5
  • 120
    • 0027163281 scopus 로고
    • Dose-related inhibition by dietary phenethyl isothiocyanate of esophageal tumorigenesis and DNA methylation induced by N-nitrosomethylbenzylamine in rats
    • [120] M.A. Morse, H. Zu, A.J. Galati, C.J. Schmidt and G.D. Stoner, Dose-related inhibition by dietary phenethyl isothiocyanate of esophageal tumorigenesis and DNA methylation induced by N-nitrosomethylbenzylamine in rats, Cancer Lett., 72 (1993) 103-110.
    • (1993) Cancer Lett. , vol.72 , pp. 103-110
    • Morse, M.A.1    Zu, H.2    Galati, A.J.3    Schmidt, C.J.4    Stoner, G.D.5
  • 121
    • 0025846911 scopus 로고
    • Inhibitory effects of phenethyl isothiocyanate on N-nitrosobenzylmethylamine carcinogenesis in the rat esophagus
    • [121] G.D. Stoner, D.T. Morrissey, Y.-H. Heur, E.M. Daniel, A.J. Galati and S.A. Wagner, Inhibitory effects of phenethyl isothiocyanate on N-nitrosobenzylmethylamine carcinogenesis in the rat esophagus, Cancer Res., 51 (1991) 2063-2068.
    • (1991) Cancer Res. , vol.51 , pp. 2063-2068
    • Stoner, G.D.1    Morrissey, D.T.2    Heur, Y.-H.3    Daniel, E.M.4    Galati, A.J.5    Wagner, S.A.6
  • 122
    • 0026629767 scopus 로고
    • Inhibition of repairable DNA-damage in Escherichia coli K-12 cells recovered from various organs of nitrosamine-treated mice by vitamin A, phenethylisothiocyanate, oleic acid and triolein
    • [122] S. Knasmüller, W.W. Huber, H. Kienzl and R. Schulte-Hermann, Inhibition of repairable DNA-damage in Escherichia coli K-12 cells recovered from various organs of nitrosamine-treated mice by vitamin A, phenethylisothiocyanate, oleic acid and triolein, Carcinogenesis, 13 (1992) 1643-1650.
    • (1992) Carcinogenesis , vol.13 , pp. 1643-1650
    • Knasmüller, S.1    Huber, W.W.2    Kienzl, H.3    Schulte-Hermann, R.4
  • 123
    • 0027767231 scopus 로고
    • Prevention of genotoxic effects by dietary constituents in various organs of mice treated with nitrosamines
    • [123] S. Knasmüller, W.W. Huber and R. Schulte-Hermann, Prevention of genotoxic effects by dietary constituents in various organs of mice treated with nitrosamines, Basic Life Sci., 61 (1993) 447-457.
    • (1993) Basic Life Sci. , vol.61 , pp. 447-457
    • Knasmüller, S.1    Huber, W.W.2    Schulte-Hermann, R.3
  • 124
    • 0000649804 scopus 로고
    • Antigenotoxic and genotoxic effects of naturally occurring isothiocyanates (ITCs)
    • H. Kozlowska, J. Fornal and Z. Zduhczyk (Eds.), 'Dietary Cancer Prevention', Centre for Agrotechnology and Veterinary Sciences, Olszytn, Poland
    • [124] K. Fekadu, S. Musk, W. Parzefall, I. Johnson, G. Sontag, R. Schulte-Hermann, R. and S. Knasmüller, Antigenotoxic and genotoxic effects of naturally occurring isothiocyanates (ITCs), in: H. Kozlowska, J. Fornal and Z. Zduhczyk (Eds.), Proc. of the Int. Conference Euro Food Tox IV 'Bioactive substances in food of plant origin', Vol 2 'Dietary Cancer Prevention', Centre for Agrotechnology and Veterinary Sciences, Olszytn, Poland, 1994, pp. 501-507.
    • (1994) Proc. of the Int. Conference Euro Food Tox IV 'Bioactive Substances in Food of Plant Origin' , vol.2 , pp. 501-507
    • Fekadu, K.1    Musk, S.2    Parzefall, W.3    Johnson, I.4    Sontag, G.5    Schulte-Hermann, R.6    Knasmüller, S.7
  • 125
    • 0028149620 scopus 로고
    • Screening of potential chemopreventive agents using biochemical markers of carcinogenesis
    • [125] S. Sharma, J.D. Stutzman, G.J. Kelloff and V.E. Steele, Screening of potential chemopreventive agents using biochemical markers of carcinogenesis. Cancer Res., 54 (1994) 5848-5855.
    • (1994) Cancer Res. , vol.54 , pp. 5848-5855
    • Sharma, S.1    Stutzman, J.D.2    Kelloff, G.J.3    Steele, V.E.4
  • 126
    • 0027205325 scopus 로고
    • The effects of phenethyl isothiocyanate on benzo[a]pyrene-induced tumors and DNA adducts in A/J mouse lung
    • [126] G. Adam-Rodwell, M.A. Morse and G.D. Stoner, The effects of phenethyl isothiocyanate on benzo[a]pyrene-induced tumors and DNA adducts in A/J mouse lung, Cancer Lett., 71 (1993) 35-42.
    • (1993) Cancer Lett. , vol.71 , pp. 35-42
    • Adam-Rodwell, G.1    Morse, M.A.2    Stoner, G.D.3
  • 127
    • 0011436488 scopus 로고
    • Effects of isothiocyanates on benzo[a]pyrene metabolism by mouse lung and liver microsomes
    • [127] M.E. Staretz, L.A. Koenig and S.S. Hecht, Effects of isothiocyanates on benzo[a]pyrene metabolism by mouse lung and liver microsomes, Proc. Am. Assoc. Cancer Res., 36 (1995) 593.
    • (1995) Proc. Am. Assoc. Cancer Res. , vol.36 , pp. 593
    • Staretz, M.E.1    Koenig, L.A.2    Hecht, S.S.3
  • 128
    • 0030060455 scopus 로고    scopus 로고
    • Effects of phenethyl isothiocyanate on metabolism and on genotoxicity of dimethylnitrosamine and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP)
    • [128] S. Knasmtiller, M.D. Friesen, J.A. Holme, J. Alexander, R. Sanyal, F. Kassie and H. Bartsch, Effects of phenethyl isothiocyanate on metabolism and on genotoxicity of dimethylnitrosamine and 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP), Mutat. Res., 350 (1996).
    • (1996) Mutat. Res. , vol.350
    • Knasmtiller, S.1    Friesen, M.D.2    Holme, J.A.3    Alexander, J.4    Sanyal, R.5    Kassie, F.6    Bartsch, H.7
  • 129
    • 0029039279 scopus 로고
    • In vitro and in vivo antitumor activity of benzyl isothiocyanate: A natural product from Tropaeolum majus
    • [129] A.M. Pintao, M.S.S. Pais, H. Coley, L.R. Kelland and I.R. Judson, In vitro and in vivo antitumor activity of benzyl isothiocyanate: a natural product from Tropaeolum majus, Planta Med., 61 (1995) 233-236.
    • (1995) Planta Med. , vol.61 , pp. 233-236
    • Pintao, A.M.1    Pais, M.S.S.2    Coley, H.3    Kelland, L.R.4    Judson, I.R.5
  • 130
    • 0027273228 scopus 로고
    • Modifying effects of benzyl isothiocyanate and benzyl thiocyanate on DNA synthesis in primary cultures of rat hepatocytes
    • [130] S. Sugie, N. Yoshimi, A. Okumura, T. Tanaka and H. Mon, Modifying effects of benzyl isothiocyanate and benzyl thiocyanate on DNA synthesis in primary cultures of rat hepatocytes, Carcinogenesis, 14 (1993) 281-283.
    • (1993) Carcinogenesis , vol.14 , pp. 281-283
    • Sugie, S.1    Yoshimi, N.2    Okumura, A.3    Tanaka, T.4    Mon, H.5
  • 131
    • 0027433872 scopus 로고
    • Allyl isothiocyanate is selectively toxic to transformed cells of the human colorectal tumour line HT29
    • [131] S.R.R. Musk and I.T. Johnson, Allyl isothiocyanate is selectively toxic to transformed cells of the human colorectal tumour line HT29, Carcinogenesis, 14 (1993) 2079-2083.
    • (1993) Carcinogenesis , vol.14 , pp. 2079-2083
    • Musk, S.R.R.1    Johnson, I.T.2
  • 132
    • 0028997486 scopus 로고
    • Effect of alkyl chain length on inhibition of N-nitrosomethylbenzylamine-induced esophageal tumorigenesis and DNA methylation by isothiocyanates
    • [132] J.T. Wilkinson, M.A. Morse, L.A. Kresty and G.D. Stoner, Effect of alkyl chain length on inhibition of N-nitrosomethylbenzylamine-induced esophageal tumorigenesis and DNA methylation by isothiocyanates, Carcinogenesis, 16 (1995) 1011-1015.
    • (1995) Carcinogenesis , vol.16 , pp. 1011-1015
    • Wilkinson, J.T.1    Morse, M.A.2    Kresty, L.A.3    Stoner, G.D.4
  • 133
    • 0023864113 scopus 로고
    • Nucleophilic index value: Implication in the protection by indole-3-carbinol from N-nitrosodimethylamine cyto and genotoxicity in mouse liver
    • [133] H.G. Shertzer and M.W. Tabor, Nucleophilic index value: implication in the protection by indole-3-carbinol from N-nitrosodimethylamine cyto and genotoxicity in mouse liver, J. Appl. Toxicol., 8 (1988) 105-110.
    • (1988) J. Appl. Toxicol. , vol.8 , pp. 105-110
    • Shertzer, H.G.1    Tabor, M.W.2
  • 135
    • 0023856684 scopus 로고
    • Mechanisms of anti-carcinogenesis by indole-3-carbinol: Detailed in vivo DNA binding dose-response studies after dietary administration with aflatoxin B1
    • [135] R.H. Dashwood, D.N. Arbogast, A.T. Fong, J.D. Hendricks and G.S. Bailey, Mechanisms of anti-carcinogenesis by indole-3-carbinol: detailed in vivo DNA binding dose-response studies after dietary administration with aflatoxin B1, Carcinogenesis, 9 (1988) 427-432.
    • (1988) Carcinogenesis , vol.9 , pp. 427-432
    • Dashwood, R.H.1    Arbogast, D.N.2    Fong, A.T.3    Hendricks, J.D.4    Bailey, G.S.5
  • 136
    • 0024587563 scopus 로고
    • Quantitative inter-relationships between aflatoxin B1 carcinogen dose, indole-3-carbinol anti-carcinogen dose, target organ DNA adduction and final tumor response
    • [136] R.H. Dashwood, D.N. Arbogast, A.T. Fong, C. Pereira, J.D. Hendricks, and G.S. Bailey, Quantitative inter-relationships between aflatoxin B1 carcinogen dose, indole-3-carbinol anti-carcinogen dose, target organ DNA adduction and final tumor response, Carcinogenesis, 10 (1989) 175-181.
    • (1989) Carcinogenesis , vol.10 , pp. 175-181
    • Dashwood, R.H.1    Arbogast, D.N.2    Fong, A.T.3    Pereira, C.4    Hendricks, J.D.5    Bailey, G.S.6
  • 138
    • 0023853854 scopus 로고
    • Intervention in free radical mediated hepatotoxicity and lipid peroxidation by indole-3-carbinol
    • [138] H.G. Shertzer, M.L. Berger and M.W. Tabor, Intervention in free radical mediated hepatotoxicity and lipid peroxidation by indole-3-carbinol, Biochem. Pharmacol., 37 (1988) 333-338.
    • (1988) Biochem. Pharmacol. , vol.37 , pp. 333-338
    • Shertzer, H.G.1    Berger, M.L.2    Tabor, M.W.3
  • 139
    • 0029585536 scopus 로고
    • Protection by chiorophyllin and indole-3-carbinol against 2-amino-1-niethyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced DNA adducts and colonic aberrant crypts in the F344 rat
    • [139] D. Guo, H.A.J. Schut, C.D. Davis, E.G. Snyderwine, G.S. Bailey and R.H. Dashwood, Protection by chiorophyllin and indole-3-carbinol against 2-amino-1-niethyl-6-phenylimidazo[4,5-b]pyridine (PhIP)-induced DNA adducts and colonic aberrant crypts in the F344 rat, Carcinogenesis, 16 (1995) 2931-2937.
    • (1995) Carcinogenesis , vol.16 , pp. 2931-2937
    • Guo, D.1    Schut, H.A.J.2    Davis, C.D.3    Snyderwine, E.G.4    Bailey, G.S.5    Dashwood, R.H.6
  • 140
    • 0029555748 scopus 로고    scopus 로고
    • Inhibition of DNA adduct formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by dietary indole-3-carbinol (I3C) in the mammary gland, colon, and liver of the female F-344 rat
    • [140] H.A.J. Schut and R.H. Dashwood, Inhibition of DNA adduct formation of 2-amino-1-methyl-6-phenylimidazo[4,5-b]pyridine (PhIP) by dietary indole-3-carbinol (I3C) in the mammary gland, colon, and liver of the female F-344 rat, Ann. N.Y. Acad. Sci., 768 (1996) 210-214.
    • (1996) Ann. N.Y. Acad. Sci. , vol.768 , pp. 210-214
    • Schut, H.A.J.1    Dashwood, R.H.2
  • 141
    • 0028242313 scopus 로고
    • Anticarcinogenic activity of indole-3-carbinol acid products: Ultrasensitive bioassay by trout embryo microinjection
    • [141] R.H. Dashwood, A.T. Fong, D.N. Arbogast, L.F. Bjeldanes, J.D. Hendricks and G.S. Bailey, Anticarcinogenic activity of indole-3-carbinol acid products: ultrasensitive bioassay by trout embryo microinjection, Cancer Res., 54 (1994) 3617-3619.
    • (1994) Cancer Res. , vol.54 , pp. 3617-3619
    • Dashwood, R.H.1    Fong, A.T.2    Arbogast, D.N.3    Bjeldanes, L.F.4    Hendricks, J.D.5    Bailey, G.S.6
  • 143
    • 0022415177 scopus 로고
    • Effects of dietary indoles and isothiocyanates on N-nitrosodimethylamine and 4-(methyinitrosoamino)-1-(3-pyridyl)-1-butanone α-hydroxylation and DNA methylation in rat liver
    • [143] F.-L. Chung, M. Wang and S.S Hecht, Effects of dietary indoles and isothiocyanates on N-nitrosodimethylamine and 4-(methyinitrosoamino)-1-(3-pyridyl)-1-butanone α-hydroxylation and DNA methylation in rat liver, Carcinogenesis, 6 (1985) 539-543.
    • (1985) Carcinogenesis , vol.6 , pp. 539-543
    • Chung, F.-L.1    Wang, M.2    Hecht, S.S.3
  • 144
    • 0026502758 scopus 로고
    • Effect of frequency of isothiocyanate administration on inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced pulmonary adenoma formation in A/J mice
    • [144] M.A. Morse, K.I. Eklind, S.G. Amin and F.-L. Chung, Effect of frequency of isothiocyanate administration on inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone-induced pulmonary adenoma formation in A/J mice, Cancer Lett., 62 (1992) 77-81.
    • (1992) Cancer Lett. , vol.62 , pp. 77-81
    • Morse, M.A.1    Eklind, K.I.2    Amin, S.G.3    Chung, F.-L.4
  • 145
    • 0028016171 scopus 로고
    • Structure-activity relationships of isothiocyanates as mechanism-based inhibitors of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butatone-induced lung tumorigenesis in A/J mice
    • [145] D. Jiao, K.I. Eklind, C.-I. Choi, D.H. Desai, S.G. Amin and F.-L. Chung, Structure-activity relationships of isothiocyanates as mechanism-based inhibitors of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butatone-induced lung tumorigenesis in A/J mice, Cancer Res., 54 (1994) 4327-4333.
    • (1994) Cancer Res. , vol.54 , pp. 4327-4333
    • Jiao, D.1    Eklind, K.I.2    Choi, C.-I.3    Desai, D.H.4    Amin, S.G.5    Chung, F.-L.6
  • 146
    • 0024458427 scopus 로고
    • Effects of alkyl chain length on the inhibition of NNK-induced lung neoplasia in A/J mice by arylalkyl isothiocyanates
    • [146] M.A. Morse, K.I. Eklind, S.G. Amin, S.S. Hecht and F.-L. Chung, Effects of alkyl chain length on the inhibition of NNK-induced lung neoplasia in A/J mice by arylalkyl isothiocyanates, Carcinogenesis, 10 (1989) 1757-1759.
    • (1989) Carcinogenesis , vol.10 , pp. 1757-1759
    • Morse, M.A.1    Eklind, K.I.2    Amin, S.G.3    Hecht, S.S.4    Chung, F.-L.5
  • 148
    • 0025267078 scopus 로고
    • Effect of dietary aromatic isothiocyanates fed subsequent to the administration of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone on lung tumorigenicity in mice
    • [148] M.A. Morse, J.C. Reinhardt, S.G. Amin, S.S. Hecht, G.D. Stoner and F.-L. Chung, Effect of dietary aromatic isothiocyanates fed subsequent to the administration of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone on lung tumorigenicity in mice, Cancer Lett., 49 (1990) 225-230.
    • (1990) Cancer Lett. , vol.49 , pp. 225-230
    • Morse, M.A.1    Reinhardt, J.C.2    Amin, S.G.3    Hecht, S.S.4    Stoner, G.D.5    Chung, F.-L.6
  • 149
    • 0030038193 scopus 로고    scopus 로고
    • Chemopreventive efficacy of arylalkyl isothiocyanates and N-acetylcysteine for lung tumorigenesis in Fischer rats
    • [149] F.-L. Chung, G. Kelloff, V. Steele, B. Pittman, E. Zang, D. Jiao, J. Rigotty, C.-I. Choi and A. Rivenson, Chemopreventive efficacy of arylalkyl isothiocyanates and N-acetylcysteine for lung tumorigenesis in Fischer rats, Cancer Res., 56 (1996) 772-778.
    • (1996) Cancer Res. , vol.56 , pp. 772-778
    • Chung, F.-L.1    Kelloff, G.2    Steele, V.3    Pittman, B.4    Zang, E.5    Jiao, D.6    Rigotty, J.7    Choi, C.-I.8    Rivenson, A.9
  • 150
    • 0029053406 scopus 로고
    • Effects of dietary phenethyl isothiocyanate, ellagic acid, sulindac and calcium on the induction and progression of N-nitrosomethylbenzylamineinduced esophageal carcinogenesis in rats
    • [150] J.C. Siglin, D.H. Barch and G.D. Stoner, Effects of dietary phenethyl isothiocyanate, ellagic acid, sulindac and calcium on the induction and progression of N-nitrosomethylbenzylamineinduced esophageal carcinogenesis in rats, Carcinogenesis, 16 (1995) 1101-1106.
    • (1995) Carcinogenesis , vol.16 , pp. 1101-1106
    • Siglin, J.C.1    Barch, D.H.2    Stoner, G.D.3
  • 151
    • 0027517761 scopus 로고
    • Effects of isothiocyanates on tumorigenesis by benzo[a]pyrene in murine tumor models
    • [151] J.-M. Lin, S.G. Amin, N. Trushin and S.S. Hecht, Effects of isothiocyanates on tumorigenesis by benzo[a]pyrene in murine tumor models, Cancer Lett., 74 (1993) 151-159.
    • (1993) Cancer Lett. , vol.74 , pp. 151-159
    • Lin, J.-M.1    Amin, S.G.2    Trushin, N.3    Hecht, S.S.4
  • 152
    • 0011392030 scopus 로고
    • Chemopreventive effects of phenethyl and 3-phenylpropyl isothiocyanates on lung and pancreatic carcinogenesis initiated with N-nitrosobis(2-oxopropyl)amine in hamsters
    • [152] A. Nishikawa, F.-L. Chung, F. Furukawa, T. Imazawa, S. Ikezaki, M. Takahashi and Y. Hayashi, Chemopreventive effects of phenethyl and 3-phenylpropyl isothiocyanates on lung and pancreatic carcinogenesis initiated with N-nitrosobis(2-oxopropyl)amine in hamsters, Proc. Am. Assoc. Cancer Res., 36 (1995)126.
    • (1995) Proc. Am. Assoc. Cancer Res. , vol.36 , pp. 126
    • Nishikawa, A.1    Chung, F.-L.2    Furukawa, F.3    Imazawa, T.4    Ikezaki, S.5    Takahashi, M.6    Hayashi, Y.7
  • 153
    • 0029937470 scopus 로고    scopus 로고
    • Chemopreventive effects of phenethyl isothiocyanate on lung and pancreatic tumorigenesis in N-nitrosobis(2-oxopropyl)amine-treated hamsters
    • [153] A. Nishikawa, F. Furukawa, C. Uneyama, S. Ikezaki, Z. Tanakamaru, F.-L. Chung, M. Takahashi and Y. Hayashi, Chemopreventive effects of phenethyl isothiocyanate on lung and pancreatic tumorigenesis in N-nitrosobis(2-oxopropyl)amine-treated hamsters, Carcinogenesis, 17 (1996) 1381-1384.
    • (1996) Carcinogenesis , vol.17 , pp. 1381-1384
    • Nishikawa, A.1    Furukawa, F.2    Uneyama, C.3    Ikezaki, S.4    Tanakamaru, Z.5    Chung, F.-L.6    Takahashi, M.7    Hayashi, Y.8
  • 154
    • 0029566974 scopus 로고
    • Chemoprevention of diethylnitrosamine-induced liver foci and hepatocellular adenomas in C3H mice
    • [154] M.A. Pereira, Chemoprevention of diethylnitrosamine-induced liver foci and hepatocellular adenomas in C3H mice, Anticancer Res., 15 (1995) 1953-1956.
    • (1995) Anticancer Res. , vol.15 , pp. 1953-1956
    • Pereira, M.A.1
  • 155
    • 0011392410 scopus 로고
    • Chemopreventive efficacy of miconazole (MCZ), anethole trithione (ATT), phenethyl isothiocyanate (PEITC), and N-acetyl-L-cysteine (NAC) in the DMBA-induced rat mammary tumor model
    • [155] V.E. Steele, R.A. Lubet, G.J. Kelloffl, I. Eto, L.M. Whitaker and C.J. Grubbs, Chemopreventive efficacy of miconazole (MCZ), anethole trithione (ATT), phenethyl isothiocyanate (PEITC), and N-acetyl-L-cysteine (NAC) in the DMBA-induced rat mammary tumor model, Proc. Am. Assoc. Cancer Res., 36 (1995) 590.
    • (1995) Proc. Am. Assoc. Cancer Res. , vol.36 , pp. 590
    • Steele, V.E.1    Lubet, R.A.2    Kelloffl, G.J.3    Eto, I.4    Whitaker, L.M.5    Grubbs, C.J.6
  • 156
    • 0017328782 scopus 로고
    • Inhibition of carcinogenic effects of polycyclic hydrocarbons by benzyl isothiocyanate and related compounds
    • [156] L.W. Wattenberg, Inhibition of carcinogenic effects of polycyclic hydrocarbons by benzyl isothiocyanate and related compounds, J. Natl. Cancer Inst., 58 (1977) 395-398.
    • (1977) J. Natl. Cancer Inst. , vol.58 , pp. 395-398
    • Wattenberg, L.W.1
  • 157
    • 0019467613 scopus 로고
    • Inhibition of carcinogen-induced neoplasia by sodium cyanate, tert-butyl isothiocyanate, and benzyl isothiocyanate administered subsequent to carcinogen exposure
    • [157] L.W. Wattenberg, Inhibition of carcinogen-induced neoplasia by sodium cyanate, tert-butyl isothiocyanate, and benzyl isothiocyanate administered subsequent to carcinogen exposure, Cancer Res., 41 (1981) 2991-2994.
    • (1981) Cancer Res. , vol.41 , pp. 2991-2994
    • Wattenberg, L.W.1
  • 158
    • 0023616165 scopus 로고
    • Inhibitory effects of benzyl isothiocyanate administered shortly before diethylnitrosamine or benzo[a]pyrene on pulmonary and forestomach neoplasia in A/J mice
    • [158] L.W. Wattenberg, Inhibitory effects of benzyl isothiocyanate administered shortly before diethylnitrosamine or benzo[a]pyrene on pulmonary and forestomach neoplasia in A/J mice, Carcinogenesis, 8 (1987) 1971-1973.
    • (1987) Carcinogenesis , vol.8 , pp. 1971-1973
    • Wattenberg, L.W.1
  • 159
    • 0027327820 scopus 로고
    • Inhibitory effects of benzyl isothiocyanate and benzyl thiocyanate on diethylnitrosamine-induced hepatocarcinogenesis in rats
    • [159] S. Sugie, A. Okumura, T. Tanaka and H. Mon, Inhibitory effects of benzyl isothiocyanate and benzyl thiocyanate on diethylnitrosamine-induced hepatocarcinogenesis in rats, Jpn. J. Cancer Res., 84 (1993) 865-870.
    • (1993) Jpn. J. Cancer Res. , vol.84 , pp. 865-870
    • Sugie, S.1    Okumura, A.2    Tanaka, T.3    Mon, H.4
  • 160
    • 0028566646 scopus 로고
    • Lung tumor induction in A/J mice by the tobacco smoke carcinogens 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene: A potentially useful model for evaluation of chemopreventive agents
    • [160] S.S. Hecht, S. Isaacs and N. Trushin, Lung tumor induction in A/J mice by the tobacco smoke carcinogens 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone and benzo[a]pyrene: a potentially useful model for evaluation of chemopreventive agents, Carcinogenesis, 15 (1994) 2721-2725.
    • (1994) Carcinogenesis , vol.15 , pp. 2721-2725
    • Hecht, S.S.1    Isaacs, S.2    Trushin, N.3
  • 161
    • 0030000586 scopus 로고    scopus 로고
    • Chemopreventive effects of 3-phenylpropyl isothiocyanate on hamster lung tumorigenesis initiated with N-nitrosobis(2-oxopropyl)amine
    • [161] A. Nishikawa, F. Furukawa, S. Ikezaki, Z. Tanakamaru, F.-L. Chung, M. Takahashi and Y. Hayashi, Chemopreventive effects of 3-phenylpropyl isothiocyanate on hamster lung tumorigenesis initiated with N-nitrosobis(2-oxopropyl)amine, Jpn. J. Cancer Res., 87 (1996) 122-126.
    • (1996) Jpn. J. Cancer Res. , vol.87 , pp. 122-126
    • Nishikawa, A.1    Furukawa, F.2    Ikezaki, S.3    Tanakamaru, Z.4    Chung, F.-L.5    Takahashi, M.6    Hayashi, Y.7
  • 162
    • 0027220529 scopus 로고
    • Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone mouse lung tumorigenesis by arylalkynes, mechanism-based inactivators of cytochrome P450
    • [162] W.L. Alworth, R. Young-Sciame and S.S. Hecht, Inhibition of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone mouse lung tumorigenesis by arylalkynes, mechanism-based inactivators of cytochrome P450, Carcinogenesis, 14 (1993) 1711-1713.
    • (1993) Carcinogenesis , vol.14 , pp. 1711-1713
    • Alworth, W.L.1    Young-Sciame, R.2    Hecht, S.S.3
  • 165
    • 0028203252 scopus 로고
    • Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates
    • [165] Y. Zhang, T.W. Kensler, C.-G. Cho, G.H. Posner and P. Talalay, Anticarcinogenic activities of sulforaphane and structurally related synthetic norbornyl isothiocyanates, Proc. Natl. Acad. Sci. USA, 91 (1994) 3147-3150.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 3147-3150
    • Zhang, Y.1    Kensler, T.W.2    Cho, C.-G.3    Posner, G.H.4    Talalay, P.5
  • 166
    • 0027278761 scopus 로고
    • Estrogen metabolism and human papillomavirus-induced tumors of the larynx: Chemo-prophylaxis with indole-3-carbinol
    • [166] L. Newfield, A. Goldsmith, H.L. Bradlow and K. Auborn, Estrogen metabolism and human papillomavirus-induced tumors of the larynx: chemo-prophylaxis with indole-3-carbinol, Anticancer Res., 13 (1993) 337-342.
    • (1993) Anticancer Res. , vol.13 , pp. 337-342
    • Newfield, L.1    Goldsmith, A.2    Bradlow, H.L.3    Auborn, K.4
  • 167
    • 0025922716 scopus 로고
    • 1 carcinogenesis by the natural tumor modulator indole-3-carbinol: Influence of dose, duration, and intermittent exposure on indole-3-carbinol promotional potency
    • 1 carcinogenesis by the natural tumor modulator indole-3-carbinol: influence of dose, duration, and intermittent exposure on indole-3-carbinol promotional potency, Cancer Res., 51 (1991) 2362-2365.
    • (1991) Cancer Res. , vol.51 , pp. 2362-2365
    • Dashwood, R.H.1    Fong, A.T.2    Williams, D.E.3    Hendricks, J.D.4    Bailey, G.S.5
  • 169
    • 0022494298 scopus 로고
    • Multiple dietary factors in the enhancement of dimethylhydrazine carcinogenesis: Main effect of indole-3-carbinol
    • [169] B.C. Pence, F. Buddingh and S.P. Yang, Multiple dietary factors in the enhancement of dimethylhydrazine carcinogenesis: main effect of indole-3-carbinol, J. Natl Cancer Inst., 77 (1986) 269-276.
    • (1986) J. Natl Cancer Inst. , vol.77 , pp. 269-276
    • Pence, B.C.1    Buddingh, F.2    Yang, S.P.3
  • 170
    • 0025818622 scopus 로고
    • Modifying responses of allyl sulfide, indole-3-carbinol and germanium in a rat multi-organ carcinogenesis model
    • [170] J.J. Jang, K.J. Cho, Y.S. Lee and J.H. Bae, Modifying responses of allyl sulfide, indole-3-carbinol and germanium in a rat multi-organ carcinogenesis model, Carcinogenesis, 12 (1991) 691-695.
    • (1991) Carcinogenesis , vol.12 , pp. 691-695
    • Jang, J.J.1    Cho, K.J.2    Lee, Y.S.3    Bae, J.H.4
  • 171
    • 0028298317 scopus 로고
    • Biphasic modifying effect of indole-3-carbinol on diethylnitrosamine-induced preneoplastic glutathione S-transferase placental form-positive liver cell foci in Sprague-Dawley rats
    • [171] D.J. Kim, K.K. Lee, B.S. Han, B. Ann, J.H. Bae and J.J. Jang, Biphasic modifying effect of indole-3-carbinol on diethylnitrosamine-induced preneoplastic glutathione S-transferase placental form-positive liver cell foci in Sprague-Dawley rats, Jpn. J. Cancer Res., 85 (1994) 578-583.
    • (1994) Jpn. J. Cancer Res. , vol.85 , pp. 578-583
    • Kim, D.J.1    Lee, K.K.2    Han, B.S.3    Ann, B.4    Bae, J.H.5    Jang, J.J.6
  • 172
    • 0018137952 scopus 로고
    • Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles
    • [172] L.W. Wattenberg and W.D. Loub, Inhibition of polycyclic aromatic hydrocarbon-induced neoplasia by naturally occurring indoles, Cancer Res., 38 (1978) 1410-1413.
    • (1978) Cancer Res. , vol.38 , pp. 1410-1413
    • Wattenberg, L.W.1    Loub, W.D.2
  • 173
    • 0025140870 scopus 로고
    • Inhibitory effect of sinigrin and indole-3-carbinol on diethylnitrosamine-induced hepatocarcinogenesis in male ACI/N rats
    • [173] T. Tanaka, Y. Mon, Y. Morishita, A. Hara, T. Ohno, T. Kojima and H. Mon, Inhibitory effect of sinigrin and indole-3-carbinol on diethylnitrosamine-induced hepatocarcinogenesis in male ACI/N rats, Carcinogenesis, 11 (1990) 1403-1406.
    • (1990) Carcinogenesis , vol.11 , pp. 1403-1406
    • Tanaka, T.1    Mon, Y.2    Morishita, Y.3    Hara, A.4    Ohno, T.5    Kojima, T.6    Mon, H.7
  • 174
    • 0026785514 scopus 로고
    • Inhibitory effects of the natural products indole-3-carbinol and sinigrin during initiation and promotion phases of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis
    • [174] T. Tanaka, T. Kojima, Y. Morishita and H. Mon, Inhibitory effects of the natural products indole-3-carbinol and sinigrin during initiation and promotion phases of 4-nitroquinoline 1-oxide-induced rat tongue carcinogenesis, Jpn. J. Cancer Res., 83 (1992) 835-842.
    • (1992) Jpn. J. Cancer Res. , vol.83 , pp. 835-842
    • Tanaka, T.1    Kojima, T.2    Morishita, Y.3    Mon, H.4
  • 175
    • 0020587373 scopus 로고
    • Inhibition of neoplasia by minor dietary constituents
    • [175] L.W. Wattenberg, Inhibition of neoplasia by minor dietary constituents, Cancer Res., 43 (1983) 2448s-2453s.
    • (1983) Cancer Res. , vol.43
    • Wattenberg, L.W.1
  • 177
    • 0023940429 scopus 로고
    • Protective effect of dietary Brussels sprouts against mammary carcinogenesis in Sprague-Dawley rats
    • [177] G.S. Stoewsand, J.L. Anderson and L. Munson, Protective effect of dietary Brussels sprouts against mammary carcinogenesis in Sprague-Dawley rats, Cancer Lett., 39 (1988) 199-207.
    • (1988) Cancer Lett. , vol.39 , pp. 199-207
    • Stoewsand, G.S.1    Anderson, J.L.2    Munson, L.3
  • 178
    • 0020328392 scopus 로고
    • 1-induced rat plasma α-foetoprotein elevation, hepatic tumorigenesis, and mutagenicity of urine
    • 1-induced rat plasma α-foetoprotein elevation, hepatic tumorigenesis, and mutagenicity of urine, Food Chem. Toxicol., 20 (1982) 47-52.
    • (1982) Food Chem. Toxicol. , vol.20 , pp. 47-52
    • Boyd, J.N.1    Babish, J.G.2    Stoewsand, G.S.3
  • 179
    • 84987550815 scopus 로고
    • Effects of dietary cabbage on the tumorigenicity of 1,2-dimethylhydrazine in mice
    • [179] C. Srisangam, D.G. Hendricks, R.P. Sharma, D.K. Salunkhe and A.W. Mahoney, Effects of dietary cabbage on the tumorigenicity of 1,2-dimethylhydrazine in mice, J. Food Saf., 4 (1980) 235-245.
    • (1980) J. Food Saf. , vol.4 , pp. 235-245
    • Srisangam, C.1    Hendricks, D.G.2    Sharma, R.P.3    Salunkhe, D.K.4    Mahoney, A.W.5
  • 180
    • 0025327826 scopus 로고
    • Reduction in mammary tumorigenesis in the rat by cabbage and cabbage residue
    • [180] E. Bresnick, D.F. Birt, K. Wolterman, M. Wheeler and R.S. Markin, Reduction in mammary tumorigenesis in the rat by cabbage and cabbage residue, Carcinogenesis, 11 (1990) 1159-1163.
    • (1990) Carcinogenesis , vol.11 , pp. 1159-1163
    • Bresnick, E.1    Birt, D.F.2    Wolterman, K.3    Wheeler, M.4    Markin, R.S.5
  • 181
    • 0024602804 scopus 로고
    • The effect of diets enriched in cabbage and collards on murine pulmonary metastasis
    • [181] E.M. Scholar, K. Wolterman, D.F. Birt and E. Bresnick, The effect of diets enriched in cabbage and collards on murine pulmonary metastasis, Nutr. Cancer, 12 (1989) 121-126.
    • (1989) Nutr. Cancer , vol.12 , pp. 121-126
    • Scholar, E.M.1    Wolterman, K.2    Birt, D.F.3    Bresnick, E.4
  • 182
    • 0025369908 scopus 로고
    • Induction of estradiol metabolism by dietary indole-3-carbinol in humans
    • [182] J.J. Michnovicz and H.L. Bradlow, Induction of estradiol metabolism by dietary indole-3-carbinol in humans, J. Natl Cancer Inst., 82 (1990) 947-949.
    • (1990) J. Natl Cancer Inst. , vol.82 , pp. 947-949
    • Michnovicz, J.J.1    Bradlow, H.L.2
  • 183
    • 0025781767 scopus 로고
    • Altered estrogen metabolism and excretion in humans following consumption of indole-3-carbinol
    • [183] J.J. Michnovicz and H.L. Bradlow, Altered estrogen metabolism and excretion in humans following consumption of indole-3-carbinol, Nutr. Cancer, 16 (1991) 59-66.
    • (1991) Nutr. Cancer , vol.16 , pp. 59-66
    • Michnovicz, J.J.1    Bradlow, H.L.2
  • 186
    • 0028179830 scopus 로고
    • Consumption of Brussels sprouts results in elevated α-class glutathione s-transferase levels in human blood plasma
    • [186] J.J. Bogaards, H. Verhagen, M.I. Willems, G. van Poppel and P.J. van Bladeren, Consumption of Brussels sprouts results in elevated α-class glutathione S-transferase levels in human blood plasma, Carcinogenesis, 15 (1994) 1073-1075.
    • (1994) Carcinogenesis , vol.15 , pp. 1073-1075
    • Bogaards, J.J.1    Verhagen, H.2    Willems, M.I.3    Van Poppel, G.4    Van Bladeren, P.J.5
  • 188
    • 0028968524 scopus 로고
    • Effects of consumption of Brussels sprouts on plasma and urinary glutathione S-transferase class-α and -π in humans
    • [188] W.A. Nijhoff, T.P.J. Mulder, H. Verhagen, G. van Poppel and W.H.M. Peters, Effects of consumption of Brussels sprouts on plasma and urinary glutathione S-transferase class-α and -π in humans, Carcinogenesis, 16 (1995) 955-958.
    • (1995) Carcinogenesis , vol.16 , pp. 955-958
    • Nijhoff, W.A.1    Mulder, T.P.J.2    Verhagen, H.3    Van Poppel, G.4    Peters, W.H.M.5
  • 189
  • 190
    • 0001193388 scopus 로고
    • Consumption of cruciferous vegetables-probable protection against breast cancer
    • H. Kozlowska, J. Fornal and Z. Zduflczyk (Eds.), Dietary Cancer Prevention, Centre for Agrotechnology and Veterinary Sciences, Olszytn, Poland
    • [190] S. Yannai, H.L. Bradlow, J. Westin and E.D. Richter, Consumption of cruciferous vegetables-probable protection against breast cancer, in: H. Kozlowska, J. Fornal and Z. Zduflczyk (Eds.), Proc. of the Int. Conference Euro Food Tox IV Bioactive substances in food of plant origin, 2, Dietary Cancer Prevention, Centre for Agrotechnology and Veterinary Sciences, Olszytn, Poland, 1994, pp. 480-483.
    • (1994) Proc. of the Int. Conference Euro Food Tox IV Bioactive Substances in Food of Plant Origin , vol.2 , pp. 480-483
    • Yannai, S.1    Bradlow, H.L.2    Westin, J.3    Richter, E.D.4
  • 191
    • 0029875494 scopus 로고    scopus 로고
    • Effects of dietary broccoli on human in vivo drug metabolizing enzymes: Evaluation of caffeine, oestrone and chlorzoxazone metabolism
    • [191] M.A. Kall, O. Vang and J. Clausen, Effects of dietary broccoli on human in vivo drug metabolizing enzymes: evaluation of caffeine, oestrone and chlorzoxazone metabolism. Carcinogenesis, 17 (1996) 793-799.
    • (1996) Carcinogenesis , vol.17 , pp. 793-799
    • Kall, M.A.1    Vang, O.2    Clausen, J.3
  • 192
    • 0026756018 scopus 로고
    • Foreign compound metabolism capacity in man measured from metabolites of dietary caffeine
    • [192] K. Vistisen, H.E. Poulsen and S. Loft, Foreign compound metabolism capacity in man measured from metabolites of dietary caffeine, Carcinogenesis, 13 (1992) 1561-1568.
    • (1992) Carcinogenesis , vol.13 , pp. 1561-1568
    • Vistisen, K.1    Poulsen, H.E.2    Loft, S.3
  • 193
    • 0025942605 scopus 로고
    • Cytochrome P450 1A2 activity in man measured by caffeine metabolism: Effect of smoking, broccoli and exercise
    • [193] K. Vistisen, S. Loft and H.E. Poulsen, Cytochrome P450 1A2 activity in man measured by caffeine metabolism: effect of smoking, broccoli and exercise, Adv. Exp. Med. Biol., 283 (1991) 407-411.
    • (1991) Adv. Exp. Med. Biol. , vol.283 , pp. 407-411
    • Vistisen, K.1    Loft, S.2    Poulsen, H.E.3
  • 194
    • 0001036863 scopus 로고    scopus 로고
    • In vitro cytotoxic activity of some glucosinolate-derived products generated by myrosinase hydrolysis
    • [194] C. Nastruzzi, R. Cortesi, E. Esposito, E. Menegatti, O. Leoni, R. Ion and S. Palmieri, In vitro cytotoxic activity of some glucosinolate-derived products generated by myrosinase hydrolysis, J. Agric. Food Chem., 44 (1996) 1014-1021.
    • (1996) J. Agric. Food Chem. , vol.44 , pp. 1014-1021
    • Nastruzzi, C.1    Cortesi, R.2    Esposito, E.3    Menegatti, E.4    Leoni, O.5    Ion, R.6    Palmieri, S.7
  • 195
    • 0029991908 scopus 로고    scopus 로고
    • Inhibition of human leukaemia 60 cell growth by mercapturic acid metabolites of phenylethyl isothiocyanate
    • [195] A. Adesida, L.G. Edwards and P.J. Thornalley, Inhibition of human leukaemia 60 cell growth by mercapturic acid metabolites of phenylethyl isothiocyanate, Food Chem. Toxicol., 34 (1996) 385-392.
    • (1996) Food Chem. Toxicol. , vol.34 , pp. 385-392
    • Adesida, A.1    Edwards, L.G.2    Thornalley, P.J.3
  • 197
    • 0029953164 scopus 로고    scopus 로고
    • Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1
    • [197] R. Yu, J.-J. Jiao, J.-L. Duh, T.-H. Tan and A.-N.T. Kong, Phenethyl isothiocyanate, a natural chemopreventive agent, activates c-Jun N-terminal kinase 1, Cancer Res., 56 (1996) 2954-2959.
    • (1996) Cancer Res. , vol.56 , pp. 2954-2959
    • Yu, R.1    Jiao, J.-J.2    Duh, J.-L.3    Tan, T.-H.4    Kong, A.-N.T.5
  • 198
    • 0027759781 scopus 로고
    • Influence of indole carbinols and growth hormone on the metabolism of 4-androstenedione by rat liver microsomes
    • [198] P.H. Jellinck, H.L.J. Makin, D.W. Sepkovic and H.L. Bradlow, Influence of indole carbinols and growth hormone on the metabolism of 4-androstenedione by rat liver microsomes, J. Steroid Biochem. Molec. Biol., 46 (1993) 791-798.
    • (1993) J. Steroid Biochem. Molec. Biol. , vol.46 , pp. 791-798
    • Jellinck, P.H.1    Makin, H.L.J.2    Sepkovic, D.W.3    Bradlow, H.L.4
  • 199
    • 0029941167 scopus 로고    scopus 로고
    • Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by hamster, mouse and rat intestine: Relevance of species differences
    • [199] J. Schulze, W. Schläger, R. Wünsch and E. Richter, Metabolism of 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone (NNK) by hamster, mouse and rat intestine: relevance of species differences, Carcinogenesis, 17 (1996) 1093-1099.
    • (1996) Carcinogenesis , vol.17 , pp. 1093-1099
    • Schulze, J.1    Schläger, W.2    Wünsch, R.3    Richter, E.4
  • 201
    • 0001188336 scopus 로고
    • Mutagenicity of isothiocyanates, isocyanates and thioureas on Salmonella typhimurium
    • [201] T. Yamaguchi, Mutagenicity of isothiocyanates, isocyanates and thioureas on Salmonella typhimurium, Agric. Biol. Chem., 44 (1980) 3017-3018.
    • (1980) Agric. Biol. Chem. , vol.44 , pp. 3017-3018
    • Yamaguchi, T.1
  • 202
    • 0021957853 scopus 로고
    • Allyl isothiocyanate is mutagenic in Salmonella typhimurium
    • [202] T. Neudecker and D. Henschler, Allyl isothiocyanate is mutagenic in Salmonella typhimurium, Mutat. Res., 156 (1985) 33-37.
    • (1985) Mutat. Res. , vol.156 , pp. 33-37
    • Neudecker, T.1    Henschler, D.2
  • 204
    • 0025916334 scopus 로고
    • Mutagen formation on nitrite treatment of indole compounds derived from indole-glucosinolate
    • [204] C. Sasagawa and T. Matsushima, Mutagen formation on nitrite treatment of indole compounds derived from indole-glucosinolate, Mutat. Res., 250 (1991) 169-174.
    • (1991) Mutat. Res. , vol.250 , pp. 169-174
    • Sasagawa, C.1    Matsushima, T.2
  • 206
    • 0024266512 scopus 로고
    • Formation of mutagenic N-nitroso compounds in vegetable extracts upon nitrite treatment: A comparison with the glucosinolate content
    • [206] H.G.M. Tiedink, J.A.R. Davies, L.W. van Broekhoven, H.J. van der Kamp and W.M.F. Jongen, Formation of mutagenic N-nitroso compounds in vegetable extracts upon nitrite treatment: a comparison with the glucosinolate content, Food Chem. Toxicol., 26 (1988) 947-954.
    • (1988) Food Chem. Toxicol. , vol.26 , pp. 947-954
    • Tiedink, H.G.M.1    Davies, J.A.R.2    Van Broekhoven, L.W.3    Van Der Kamp, H.J.4    Jongen, W.M.F.5
  • 207
    • 0028971324 scopus 로고
    • On the cytotoxicity and genotoxicity of allyl and phenethyl isothiocyanates and their parent glucosinolates sinigrin and gluconasturtim
    • [207] S.R.R. Musk, T.K. Smith and I.T. Johnson, On the cytotoxicity and genotoxicity of allyl and phenethyl isothiocyanates and their parent glucosinolates sinigrin and gluconasturtim, Mutat. Res., 348 (1995) 19-23.
    • (1995) Mutat. Res. , vol.348 , pp. 19-23
    • Musk, S.R.R.1    Smith, T.K.2    Johnson, I.T.3
  • 209
    • 0027225321 scopus 로고
    • The clastogenic effects of isothiocyanates
    • [209] S.R.R. Musk and I.T. Johnson, The clastogenic effects of isothiocyanates, Mutat. Res., 300 (1993) 111-117.
    • (1993) Mutat. Res. , vol.300 , pp. 111-117
    • Musk, S.R.R.1    Johnson, I.T.2
  • 210
    • 0023543506 scopus 로고
    • Neoplastic transformation of Chinese hamster cells in vitro after treatment with flavoring agents
    • [210] A. Kasamaki, T. Yasuhara and S. Urasawa, Neoplastic transformation of Chinese hamster cells in vitro after treatment with flavoring agents, J. Toxicol. Sci., 12 (1987) 383-396.
    • (1987) J. Toxicol. Sci. , vol.12 , pp. 383-396
    • Kasamaki, A.1    Yasuhara, T.2    Urasawa, S.3
  • 212
    • 0025092399 scopus 로고
    • Several known indole compounds are not important precursors of direct mutagenic N-nitroso compounds in green cabbage
    • [212] H.G.M. Tiedink, A.M. Hissink, S.M. Lodema, L.W. van Broekhoven and W.M.F. Jongen, Several known indole compounds are not important precursors of direct mutagenic N-nitroso compounds in green cabbage, Mutat. Res., 232 (1990) 199-207.
    • (1990) Mutat. Res. , vol.232 , pp. 199-207
    • Tiedink, H.G.M.1    Hissink, A.M.2    Lodema, S.M.3    Van Broekhoven, L.W.4    Jongen, W.M.F.5
  • 214
    • 84984434579 scopus 로고
    • Subacute oral toxicity study of benzyl isothiocyanate in rats
    • [214] H.-J. Lewerenz, D.W.R. Bleyl and R. Plass, Subacute oral toxicity study of benzyl isothiocyanate in rats, Nahrung, 36 (1992) 190-198.
    • (1992) Nahrung , vol.36 , pp. 190-198
    • Lewerenz, H.-J.1    Bleyl, D.W.R.2    Plass, R.3
  • 215
    • 0019213654 scopus 로고
    • Toxicology of glucosinolates, related compounds (nitriles, R-goitrin, isothiocyanates) and vitamin U found in cruciferae
    • [215] K. Nishie and M.E. Daxenbichler, Toxicology of glucosinolates, related compounds (nitriles, R-goitrin, isothiocyanates) and vitamin U found in cruciferae, Food Cosmet. Toxicol., 18 (1980) 159-172.
    • (1980) Food Cosmet. Toxicol. , vol.18 , pp. 159-172
    • Nishie, K.1    Daxenbichler, M.E.2
  • 216
    • 84984499035 scopus 로고
    • Rapeseed meal-glucosinolates and their antinutritional effects. Part 3. Animal growth and performance
    • [216] R. Mawson, R.K. Heany, Z. Zdunczyk and H. Kozlowska, Rapeseed meal-glucosinolates and their antinutritional effects. Part 3. Animal growth and performance, Nahrung, 38 (1994) 167-177.
    • (1994) Nahrung , vol.38 , pp. 167-177
    • Mawson, R.1    Heany, R.K.2    Zdunczyk, Z.3    Kozlowska, H.4
  • 217
    • 84984426175 scopus 로고
    • Rapeseed meal-glucosinolates and their antinutritional effects. Part 4. Goitrogenicity and internal organs abnormalities in animals
    • [217] R. Mawson, R.K. Heany, Z. Zdunczyk and H. Kozlowska, Rapeseed meal-glucosinolates and their antinutritional effects. Part 4. Goitrogenicity and internal organs abnormalities in animals, Nahrung, 38 (1994) 178-191.
    • (1994) Nahrung , vol.38 , pp. 178-191
    • Mawson, R.1    Heany, R.K.2    Zdunczyk, Z.3    Kozlowska, H.4
  • 218
    • 0025156793 scopus 로고
    • Glucosinolates toxicity in growing rats: Interactions with the hepatic detoxification system
    • [218] L. Nugon-Baudon, S. Rabot, O. Szylit and P. Raibaud, Glucosinolates toxicity in growing rats: interactions with the hepatic detoxification system, Xenobiotica, 20 (1990) 223-230.
    • (1990) Xenobiotica , vol.20 , pp. 223-230
    • Nugon-Baudon, L.1    Rabot, S.2    Szylit, O.3    Raibaud, P.4
  • 220
    • 84970479099 scopus 로고
    • Preliminary observations on the effect of dietary Brussels sprouts on thyroid function
    • [220] M. McMillan, E.A. Spinks and G.R. Fenwick, Preliminary observations on the effect of dietary Brussels sprouts on thyroid function, Hum. Toxicol., 5 (1986) 15-19.
    • (1986) Hum. Toxicol. , vol.5 , pp. 15-19
    • McMillan, M.1    Spinks, E.A.2    Fenwick, G.R.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.