Elevation in intracellular long-chain acyl-coenzyme A esters lead to reduced β-cell excitability via activation of adenosine 5′-triphosphate-sensitive potassium channels

Endocrinology

Volumn 149, Issue 7, 2008, Pages 3679-3687

  Webster, Nicola J ^a   Searle, Gavin J ^a   Lam, Patrick P L ^b   Huang, Ya Chi ^b   Riedel, Michael J ^c   Harb, George ^a   Gaisano, Herbert Y ^b   Holt, Andrew ^a   Light, Peter E ^a  

^a UNIVERSITY OF ALBERTA   (Canada)

^b UNIVERSITY OF TORONTO   (Canada)

^c UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ACYL COENZYME A; ADENOSINE TRIPHOSPHATE; GLUCOSE; LINOLEIC ACID; LONG CHAIN FATTY ACID COENZYME A LIGASE; OLEIC ACID; PALMITIC ACID; POTASSIUM CHANNEL; SULFONYLUREA; TOLBUTAMIDE;

ANIMAL CELL; ARTICLE; ELECTROPHYSIOLOGY; EXCITABILITY; INSULIN RELEASE; MOUSE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; OBESITY; PANCREAS ISLET BETA CELL; PRIORITY JOURNAL; PROTEIN EXPRESSION;

ACYL COENZYME A; ADENOSINE DIPHOSPHATE; ADENOSINE TRIPHOSPHATE; ANIMALS; BLOTTING, WESTERN; CELLS, CULTURED; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; COENZYME A LIGASES; INSULIN-SECRETING CELLS; KATP CHANNELS; MEMBRANE POTENTIALS; MICE; MICE, INBRED BALB C; PATCH-CLAMP TECHNIQUES; TOLBUTAMIDE;

EID: 46349099802     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2007-1138     Document Type: Article

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