메뉴 건너뛰기




Volumn 147, Issue 10, 2006, Pages 4655-4663

Oscillatory membrane potential response to glucose in islet β-cells: A comparison of islet-cell electrical activity in mouse and rat

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; GLUCAGON; GLUCOSE; INSULIN;

EID: 33748753770     PISSN: 00137227     EISSN: 00137227     Source Type: Journal    
DOI: 10.1210/en.2006-0424     Document Type: Article
Times cited : (60)

References (57)
  • 1
    • 0021679735 scopus 로고
    • Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic B-cells
    • Henquin JC, Meissner HP 1984 Significance of ionic fluxes and changes in membrane potential for stimulus-secretion coupling in pancreatic B-cells. Experientia 40:1043-1052
    • (1984) Experientia , vol.40 , pp. 1043-1052
    • Henquin, J.C.1    Meissner, H.P.2
  • 2
    • 0025869913 scopus 로고
    • Widespread synchronous [Ca2+]i oscillations due to bursting electrical activity in single pancreatic islets
    • Santos RM, Rosario LM, Nadal A, Garcia-Sancho J, Soria B, Valdeolmillos M 1991 Widespread synchronous [Ca2+]i oscillations due to bursting electrical activity in single pancreatic islets. Pflugers Arch 418:417-422
    • (1991) Pflugers Arch , vol.418 , pp. 417-422
    • Santos, R.M.1    Rosario, L.M.2    Nadal, A.3    Garcia-Sancho, J.4    Soria, B.5    Valdeolmillos, M.6
  • 3
    • 0037961599 scopus 로고    scopus 로고
    • The Ca2+ dynamics of isolated mouse β-cells and islets: Implications for mathematical models
    • Zhang M, Goforth P, Bertram R, Sherman A, Satin L 2003 The Ca2+ dynamics of isolated mouse β-cells and islets: implications for mathematical models. Biophys J 84:2852-2870
    • (2003) Biophys J , vol.84 , pp. 2852-2870
    • Zhang, M.1    Goforth, P.2    Bertram, R.3    Sherman, A.4    Satin, L.5
  • 4
    • 0029657938 scopus 로고    scopus 로고
    • Glucose-induced [Ca2+]i oscillations in single human pancreatic islets
    • Martin F, Soria B 1996 Glucose-induced [Ca2+]i oscillations in single human pancreatic islets. Cell Calcium 20:409-414
    • (1996) Cell Calcium , vol.20 , pp. 409-414
    • Martin, F.1    Soria, B.2
  • 5
    • 0028036509 scopus 로고
    • Oscillations in cytoplasmic free calcium concentration in human pancreatic islets from subjects with normal and impaired glucose tolerance
    • Kindmark H, Kohler M, Arkhammar P, Efendic S, Larsson O, Linder S, Nilsson T, Berggren PO 1994 Oscillations in cytoplasmic free calcium concentration in human pancreatic islets from subjects with normal and impaired glucose tolerance. Diabetologia 37:1121-1131
    • (1994) Diabetologia , vol.37 , pp. 1121-1131
    • Kindmark, H.1    Kohler, M.2    Arkhammar, P.3    Efendic, S.4    Larsson, O.5    Linder, S.6    Nilsson, T.7    Berggren, P.O.8
  • 6
    • 0024386388 scopus 로고
    • 'Perforated patch recording' allows long-term monitoring of metabolite-induced electrical activity and voltage-dependent Ca2+ currents in pancreatic islet B-cells
    • Falke LC, Gillis KD, Pressel DM, Misler S 1989 'Perforated patch recording' allows long-term monitoring of metabolite-induced electrical activity and voltage-dependent Ca2+ currents in pancreatic islet B-cells. FEBS Lett 251:167-172
    • (1989) FEBS Lett , vol.251 , pp. 167-172
    • Falke, L.C.1    Gillis, K.D.2    Pressel, D.M.3    Misler, S.4
  • 7
    • 0034046772 scopus 로고    scopus 로고
    • Pathophysiology of impaired pulsatile insulin release
    • Bergsten P 2000 Pathophysiology of impaired pulsatile insulin release. Diabetes Metab Res Rev 16:179-191
    • (2000) Diabetes Metab Res Rev , vol.16 , pp. 179-191
    • Bergsten, P.1
  • 8
    • 0036311359 scopus 로고    scopus 로고
    • Role of oscillations in membrane potential, cytoplasmic Ca2+, and metabolism for plasma insulin oscillations
    • Bergsten P 2002 Role of oscillations in membrane potential, cytoplasmic Ca2+, and metabolism for plasma insulin oscillations. Diabetes 51(Suppl 1):S171-S176
    • (2002) Diabetes , vol.51 , Issue.1 SUPPL.
    • Bergsten, P.1
  • 9
    • 0026472989 scopus 로고
    • Glucose-induced insulin release in islets of young rats: Time-dependent potentiation and effects of 2-bromostearate
    • Bliss CR, Sharp GW 1992 Glucose-induced insulin release in islets of young rats: time-dependent potentiation and effects of 2-bromostearate. Am J Physiol 263:E890-E896
    • (1992) Am J Physiol , vol.263
    • Bliss, C.R.1    Sharp, G.W.2
  • 10
    • 0026697083 scopus 로고
    • Stimulus-secretion coupling in β-cells of transplantable human islets of Langerhans. Evidence for a critical role for Ca2+ entry
    • Misler S, Barnett DW, Pressel DM, Gillis KD, Scharp DW, Falke LC 1992 Stimulus-secretion coupling in β-cells of transplantable human islets of Langerhans. Evidence for a critical role for Ca2+ entry. Diabetes 41:662-670
    • (1992) Diabetes , vol.41 , pp. 662-670
    • Misler, S.1    Barnett, D.W.2    Pressel, D.M.3    Gillis, K.D.4    Scharp, D.W.5    Falke, L.C.6
  • 11
    • 0021359657 scopus 로고
    • Rat islet-cells have glucose-dependent periodic electrical activity
    • Ikeuchi M, Fujimoto WY, Cook DL 1984 Rat islet-cells have glucose-dependent periodic electrical activity. Horm Metab Res 16:125-127
    • (1984) Horm Metab Res , vol.16 , pp. 125-127
    • Ikeuchi, M.1    Fujimoto, W.Y.2    Cook, D.L.3
  • 12
    • 0033669565 scopus 로고    scopus 로고
    • Differential patterns of glucose-induced electrical activity and intracellular calcium responses in single mouse and rat pancreatic islets
    • Antunes CM, Salgado AP, Rosario LM, Santos RM 2000 Differential patterns of glucose-induced electrical activity and intracellular calcium responses in single mouse and rat pancreatic islets. Diabetes 49:2028-2038
    • (2000) Diabetes , vol.49 , pp. 2028-2038
    • Antunes, C.M.1    Salgado, A.P.2    Rosario, L.M.3    Santos, R.M.4
  • 13
    • 2042435747 scopus 로고    scopus 로고
    • Tacrolimus impairment of insulin secretion in isolated rat islets occurs at multiple distal sites in stimulus-secretion coupling
    • Uchizono Y, Iwase M, Nakamura U, Sasaki N, Goto D, Iida M 2004 Tacrolimus impairment of insulin secretion in isolated rat islets occurs at multiple distal sites in stimulus-secretion coupling. Endocrinology 145:2264-2272
    • (2004) Endocrinology , vol.145 , pp. 2264-2272
    • Uchizono, Y.1    Iwase, M.2    Nakamura, U.3    Sasaki, N.4    Goto, D.5    Iida, M.6
  • 14
    • 0025827061 scopus 로고
    • Oscillations in cytosolic free Ca2+, oxygen consumption, and insulin secretion in glucose-stimulated rat pancreatic islets
    • Longo EA, Tornheim K, Deeney JT, Varnum BA, Tillotson D, Prentki M, Corkey BE 1991 Oscillations in cytosolic free Ca2+, oxygen consumption, and insulin secretion in glucose-stimulated rat pancreatic islets. J Biol Chem 266:9314-9319
    • (1991) J Biol Chem , vol.266 , pp. 9314-9319
    • Longo, E.A.1    Tornheim, K.2    Deeney, J.T.3    Varnum, B.A.4    Tillotson, D.5    Prentki, M.6    Corkey, B.E.7
  • 15
    • 0032978644 scopus 로고    scopus 로고
    • Inhibition by simvastatin, but not pravastatin, of glucose-induced cytosolic Ca2+ signalling and insulin secretion due to blockade of L-type Ca2+ channels in rat islet β-cells
    • Yada T, Nakata M, Shiraishi T, Kakei M 1999 Inhibition by simvastatin, but not pravastatin, of glucose-induced cytosolic Ca2+ signalling and insulin secretion due to blockade of L-type Ca2+ channels in rat islet β-cells. Br J Pharmacol 126:1205-1213
    • (1999) Br J Pharmacol , vol.126 , pp. 1205-1213
    • Yada, T.1    Nakata, M.2    Shiraishi, T.3    Kakei, M.4
  • 17
    • 0029962599 scopus 로고    scopus 로고
    • Glucose-induced oscillatory insulin secretion in perifused rat pancreatic islets and clonal β-cells (HIT)
    • Cunningham BA, Deeney JT, Bliss CR, Corkey BE, Tornheim K 1996 Glucose-induced oscillatory insulin secretion in perifused rat pancreatic islets and clonal β-cells (HIT). Am J Physiol 271:E702-E710
    • (1996) Am J Physiol , vol.271
    • Cunningham, B.A.1    Deeney, J.T.2    Bliss, C.R.3    Corkey, B.E.4    Tornheim, K.5
  • 18
    • 0027260802 scopus 로고
    • Glucose-induced cycles of insulin release can be resolved into distinct periods of secretory activity
    • Bergsten P, Hellman B 1993 Glucose-induced cycles of insulin release can be resolved into distinct periods of secretory activity. Biochem Biophys Res Commun 192:1182-1188
    • (1993) Biochem Biophys Res Commun , vol.192 , pp. 1182-1188
    • Bergsten, P.1    Hellman, B.2
  • 19
    • 0027172931 scopus 로고
    • Glucose-induced amplitude regulation of pulsatile insulin secretion from individual pancreatic islets
    • Bergsten P, Hellman B 1993 Glucose-induced amplitude regulation of pulsatile insulin secretion from individual pancreatic islets. Diabetes 42:670-674
    • (1993) Diabetes , vol.42 , pp. 670-674
    • Bergsten, P.1    Hellman, B.2
  • 20
    • 2442650287 scopus 로고    scopus 로고
    • Capacitance measurements of exocytosis in mouse pancreatic α-, β- and δ-cells within intact islets of Langerhans
    • Gopel S, Zhang Q, Eliasson L, Ma XS, Galvanovskis J, Kanno T, Salehi A, Rorsman P 2004 Capacitance measurements of exocytosis in mouse pancreatic α-, β- and δ-cells within intact islets of Langerhans. J Physiol 556:711-726
    • (2004) J Physiol , vol.556 , pp. 711-726
    • Gopel, S.1    Zhang, Q.2    Eliasson, L.3    Ma, X.S.4    Galvanovskis, J.5    Kanno, T.6    Salehi, A.7    Rorsman, P.8
  • 21
    • 0034325296 scopus 로고    scopus 로고
    • Regulation of glucagon release in mouse cells by KATP channels and inactivation of TTX-sensitive Na+ channels
    • Gopel SO, Kanno T, Barg S, Weng XG, Gromada J, Rorsman P 2000 Regulation of glucagon release in mouse cells by KATP channels and inactivation of TTX-sensitive Na+ channels. J Physiol 528:509-520
    • (2000) J Physiol , vol.528 , pp. 509-520
    • Gopel, S.O.1    Kanno, T.2    Barg, S.3    Weng, X.G.4    Gromada, J.5    Rorsman, P.6
  • 23
    • 0036905897 scopus 로고    scopus 로고
    • Glucose-dependent regulation of rhythmic action potential firing in pancreatic β-cells by K(ATP)-channel modulation
    • Kanno T, Rorsman P, Gopel SO 2002 Glucose-dependent regulation of rhythmic action potential firing in pancreatic β-cells by K(ATP)-channel modulation. J Physiol 545:501-507
    • (2002) J Physiol , vol.545 , pp. 501-507
    • Kanno, T.1    Rorsman, P.2    Gopel, S.O.3
  • 24
    • 0031942436 scopus 로고    scopus 로고
    • Identification of α-and β-cells in intact isolated islets of Langerhans by their characteristic cytoplasmic Ca2+ concentration dynamics and immunocytochemical staining
    • Asada N, Shibuya I, Iwanaga T, Niwa K, Kanno T 1998 Identification of α-and β-cells in intact isolated islets of Langerhans by their characteristic cytoplasmic Ca2+ concentration dynamics and immunocytochemical staining. Diabetes 47:751-757
    • (1998) Diabetes , vol.47 , pp. 751-757
    • Asada, N.1    Shibuya, I.2    Iwanaga, T.3    Niwa, K.4    Kanno, T.5
  • 25
    • 1442343000 scopus 로고    scopus 로고
    • A store-operated mechanism determines the activity of the electrically excitable glucagon-secreting pancreatic α-cell
    • Liu YJ, Vieira E, Gylfe E 2004 A store-operated mechanism determines the activity of the electrically excitable glucagon-secreting pancreatic α-cell. Cell Calcium 35:357-365
    • (2004) Cell Calcium , vol.35 , pp. 357-365
    • Liu, Y.J.1    Vieira, E.2    Gylfe, E.3
  • 26
    • 0033850226 scopus 로고    scopus 로고
    • Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting α-cells
    • Barg S, Galvanovskis J, Gopel SO, Rorsman P, Eliasson L 2000 Tight coupling between electrical activity and exocytosis in mouse glucagon-secreting α-cells. Diabetes 49:1500-1510
    • (2000) Diabetes , vol.49 , pp. 1500-1510
    • Barg, S.1    Galvanovskis, J.2    Gopel, S.O.3    Rorsman, P.4    Eliasson, L.5
  • 28
    • 20044374696 scopus 로고    scopus 로고
    • β-Cell secretory products activate α-cell ATP-dependent potassium channels to inhibit glucagon release
    • Franklin I, Gromada J, Gjinovci A, Theander S, Wollheim CB 2005 β-Cell secretory products activate α-cell ATP-dependent potassium channels to inhibit glucagon release. Diabetes 54:1808-1815
    • (2005) Diabetes , vol.54 , pp. 1808-1815
    • Franklin, I.1    Gromada, J.2    Gjinovci, A.3    Theander, S.4    Wollheim, C.B.5
  • 29
    • 26844556580 scopus 로고    scopus 로고
    • Glucose stimulates glucagon release in single rat α-cells by mechanisms that mirror the stimulus-secretion coupling in β-cells
    • Olsen HL, Theander S, Bokvist K, Buschard K, Wollheim CB, Gromada J 2005 Glucose stimulates glucagon release in single rat α-cells by mechanisms that mirror the stimulus-secretion coupling in β-cells. Endocrinology 146:4861-4870
    • (2005) Endocrinology , vol.146 , pp. 4861-4870
    • Olsen, H.L.1    Theander, S.2    Bokvist, K.3    Buschard, K.4    Wollheim, C.B.5    Gromada, J.6
  • 30
    • 33645869578 scopus 로고    scopus 로고
    • Insulin regulates islet α-cell function by reducing KATP channel sensitivity to adenosine 5′-triphosphate inhibition
    • Leung YM, Ahmed I, Sheu L, Gao X, Hara M, Tsushima RG, Diamant NE, Gaisano HY 2006 Insulin regulates islet α-cell function by reducing KATP channel sensitivity to adenosine 5′-triphosphate inhibition. Endocrinology 147:2155-2162
    • (2006) Endocrinology , vol.147 , pp. 2155-2162
    • Leung, Y.M.1    Ahmed, I.2    Sheu, L.3    Gao, X.4    Hara, M.5    Tsushima, R.G.6    Diamant, N.E.7    Gaisano, H.Y.8
  • 33
    • 0033499813 scopus 로고    scopus 로고
    • Different effects of tolbutamide and diazoxide in α, β-, and Δ-cells within intact islets of Langerhans
    • Quesada I, Nadal A, Soria B 1999 Different effects of tolbutamide and diazoxide in α, β-, and Δ-cells within intact islets of Langerhans. Diabetes 48:2390-2397
    • (1999) Diabetes , vol.48 , pp. 2390-2397
    • Quesada, I.1    Nadal, A.2    Soria, B.3
  • 34
    • 0033563173 scopus 로고    scopus 로고
    • Homologous and heterologous asynchronicity between identified α-, β- and Δ-cells within intact islets of Langerhans in the mouse
    • Nadal A, Quesada I, Soria B 1999 Homologous and heterologous asynchronicity between identified α-, β- and Δ-cells within intact islets of Langerhans in the mouse. J Physiol 517(Pt 1):85-93
    • (1999) J Physiol , vol.517 , Issue.1 PART , pp. 85-93
    • Nadal, A.1    Quesada, I.2    Soria, B.3
  • 35
    • 12944307328 scopus 로고    scopus 로고
    • Functional identification and monitoring of individual α- and β-cells in cultured mouse islets of Langerhans
    • Hjortoe GM, Hagel GM, Terry BR, Thastrup O, Arkhammar PO 2004 Functional identification and monitoring of individual α- and β-cells in cultured mouse islets of Langerhans. Acta Diabetol 41:185-193
    • (2004) Acta Diabetol , vol.41 , pp. 185-193
    • Hjortoe, G.M.1    Hagel, G.M.2    Terry, B.R.3    Thastrup, O.4    Arkhammar, P.O.5
  • 36
    • 0030018046 scopus 로고    scopus 로고
    • Oscillatory patterns of electrical activity in mouse pancreatic islets of Langerhans recorded in vivo
    • Gomis A, Sanchez-Andres JV, Valdeolmillos M 1996 Oscillatory patterns of electrical activity in mouse pancreatic islets of Langerhans recorded in vivo. Pflugers Arch 432:510-515
    • (1996) Pflugers Arch , vol.432 , pp. 510-515
    • Gomis, A.1    Sanchez-Andres, J.V.2    Valdeolmillos, M.3
  • 38
    • 2142699578 scopus 로고    scopus 로고
    • Cav1.3 is preferentially coupled to glucose-induced [Ca2+]i oscillations in the pancreatic β-cell line INS-1
    • Liu G, Hilliard N, Hockerman GH 2004 Cav1.3 is preferentially coupled to glucose-induced [Ca2+]i oscillations in the pancreatic β-cell line INS-1. Mol Pharmacol 65:1269-1277
    • (2004) Mol Pharmacol , vol.65 , pp. 1269-1277
    • Liu, G.1    Hilliard, N.2    Hockerman, G.H.3
  • 39
    • 0343986289 scopus 로고    scopus 로고
    • Voltage-gated and resting membrane currents recorded from B-cells in intact mouse pancreatic islets
    • Gopel S, Kanno T, Barg S, Galvanovskis J, Rorsman P 1999 Voltage-gated and resting membrane currents recorded from B-cells in intact mouse pancreatic islets. J Physiol 521(Pt 3):717-728
    • (1999) J Physiol , vol.521 , Issue.3 PART , pp. 717-728
    • Gopel, S.1    Kanno, T.2    Barg, S.3    Galvanovskis, J.4    Rorsman, P.5
  • 40
    • 0034695641 scopus 로고    scopus 로고
    • The oscillatory behavior of pancreatic islets from mice with mitochondrial glycerol-3-phosphate dehydrogenase knockout
    • Ravier MA, Eto K, Jonkers FC, Nenquin M, Kadowaki T, Henquin JC 2000 The oscillatory behavior of pancreatic islets from mice with mitochondrial glycerol-3-phosphate dehydrogenase knockout. J Biol Chem 275:1587-1593
    • (2000) J Biol Chem , vol.275 , pp. 1587-1593
    • Ravier, M.A.1    Eto, K.2    Jonkers, F.C.3    Nenquin, M.4    Kadowaki, T.5    Henquin, J.C.6
  • 41
    • 10044256230 scopus 로고    scopus 로고
    • Calcium and glycolysis mediate multiple bursting modes in pancreatic islets
    • Bertram R, Satin L, Zhang M, Smolen P, Sherman A 2004 Calcium and glycolysis mediate multiple bursting modes in pancreatic islets. Biophys J 87:3074-3087
    • (2004) Biophys J , vol.87 , pp. 3074-3087
    • Bertram, R.1    Satin, L.2    Zhang, M.3    Smolen, P.4    Sherman, A.5
  • 42
    • 21144440769 scopus 로고    scopus 로고
    • FRET-based voltage probes for confocal imaging: Membrane potential oscillations throughout pancreatic islets
    • Kuznetsov A, Bindokas VP, Marks JD, Philipson LH 2005 FRET-based voltage probes for confocal imaging: membrane potential oscillations throughout pancreatic islets. Am J Physiol Cell Physiol 289:c224-c229
    • (2005) Am J Physiol Cell Physiol , vol.289
    • Kuznetsov, A.1    Bindokas, V.P.2    Marks, J.D.3    Philipson, L.H.4
  • 43
    • 25444440083 scopus 로고    scopus 로고
    • Pharmacological properties and functional role of Kslow current in mouse pancreatic β-cells: SK channels contribute to Kslow tail current and modulate insulin secretion
    • Zhang M, Houamed K, Kupershmidt S, Roden D, Satin LS 2005 Pharmacological properties and functional role of Kslow current in mouse pancreatic β-cells: SK channels contribute to Kslow tail current and modulate insulin secretion. J Gen Physiol 126:353-363
    • (2005) J Gen Physiol , vol.126 , pp. 353-363
    • Zhang, M.1    Houamed, K.2    Kupershmidt, S.3    Roden, D.4    Satin, L.S.5
  • 44
    • 3042643080 scopus 로고    scopus 로고
    • A direct comparison of whole-cell patch and sharp electrodes by simultaneous recording from single spinal neurons in frog tadpoles
    • Li WC, Soffe SR, Roberts A 2004 A direct comparison of whole-cell patch and sharp electrodes by simultaneous recording from single spinal neurons in frog tadpoles. J Neurophysiol 92:380-386
    • (2004) J Neurophysiol , vol.92 , pp. 380-386
    • Li, W.C.1    Soffe, S.R.2    Roberts, A.3
  • 45
    • 0021892574 scopus 로고
    • Dual-component amino-acid-mediated synaptic potentials: Excitatory drive for swimming in Xenopus embryos
    • Dale N, Roberts A 1985 Dual-component amino-acid-mediated synaptic potentials: excitatory drive for swimming in Xenopus embryos. J Physiol 363:35-59
    • (1985) J Physiol , vol.363 , pp. 35-59
    • Dale, N.1    Roberts, A.2
  • 46
    • 0042734472 scopus 로고    scopus 로고
    • Xenopus embryonic spinal neurons recorded in situ with patch-clamp electrodes - Conditional oscillators after all?
    • Aiken SP, Kuenzi FM, Dale N 2003 Xenopus embryonic spinal neurons recorded in situ with patch-clamp electrodes - conditional oscillators after all? Eur J Neurosci 18:333-343
    • (2003) Eur J Neurosci , vol.18 , pp. 333-343
    • Aiken, S.P.1    Kuenzi, F.M.2    Dale, N.3
  • 47
    • 0029417209 scopus 로고
    • Voltage-dependent Na+ and Ca2+ currents in human pancreatic islet β-cells: Evidence for roles in the generation of action potentials and insulin secretion
    • Barnett DW, Pressel DM, Misler S 1995 Voltage-dependent Na+ and Ca2+ currents in human pancreatic islet β-cells: evidence for roles in the generation of action potentials and insulin secretion. Pflugers Arch 431:272-282
    • (1995) Pflugers Arch , vol.431 , pp. 272-282
    • Barnett, D.W.1    Pressel, D.M.2    Misler, S.3
  • 48
    • 0026661115 scopus 로고
    • Electrophysiology of stimulus-secretion coupling in human β-cells
    • Misler S, Barnett DW, Gillis KD, Pressel DM 1992 Electrophysiology of stimulus-secretion coupling in human β-cells. Diabetes 41:1221-1228
    • (1992) Diabetes , vol.41 , pp. 1221-1228
    • Misler, S.1    Barnett, D.W.2    Gillis, K.D.3    Pressel, D.M.4
  • 49
    • 0032877316 scopus 로고    scopus 로고
    • Impact of lack of suppression of glucagon on glucose tolerance in humans
    • Shah P, Basu A, Basu R, Rizza R 1999 Impact of lack of suppression of glucagon on glucose tolerance in humans. Am J Physiol 277:E283-E290
    • (1999) Am J Physiol , vol.277
    • Shah, P.1    Basu, A.2    Basu, R.3    Rizza, R.4
  • 50
    • 0018746972 scopus 로고
    • Glucagon and diabetes: A reappraisal
    • Lefebvre PJ, Luyckx AS 1979 Glucagon and diabetes: a reappraisal. Diabetologia 16:347-354
    • (1979) Diabetologia , vol.16 , pp. 347-354
    • Lefebvre, P.J.1    Luyckx, A.S.2
  • 51
    • 0018602891 scopus 로고
    • Evidence for divergent glucose effects on calcium metabolism in pancreatic β- and α2-cells
    • Berggren PO, Ostenson CG, Petersson B, Hellman B 1979 Evidence for divergent glucose effects on calcium metabolism in pancreatic β- and α2-cells. Endocrinology 105:1463-1468
    • (1979) Endocrinology , vol.105 , pp. 1463-1468
    • Berggren, P.O.1    Ostenson, C.G.2    Petersson, B.3    Hellman, B.4
  • 52
    • 20044394745 scopus 로고    scopus 로고
    • Glucose or insulin, but not zinc ions, inhibit glucagon secretion from mouse pancreatic α-cells
    • Ravier MA, Rutter GA 2005 Glucose or insulin, but not zinc ions, inhibit glucagon secretion from mouse pancreatic α-cells. Diabetes 54:1789-1797
    • (2005) Diabetes , vol.54 , pp. 1789-1797
    • Ravier, M.A.1    Rutter, G.A.2
  • 53
    • 0034671169 scopus 로고    scopus 로고
    • Zinc-induced changes in ionic currents of clonal rat pancreatic β-cells: Activation of ATP-sensitive K+ channels
    • Bloc A, Cens T, Cruz H, Dunant Y 2000 Zinc-induced changes in ionic currents of clonal rat pancreatic β-cells: activation of ATP-sensitive K+ channels. J Physiol 529(Pt 3):723-734
    • (2000) J Physiol , vol.529 , Issue.3 PART , pp. 723-734
    • Bloc, A.1    Cens, T.2    Cruz, H.3    Dunant, Y.4
  • 54
    • 1442334215 scopus 로고    scopus 로고
    • GABA in the endocrine pancreas: Its putative role as an islet-cell paracrine-signalling molecule
    • Franklin IK, Wollheim CB 2004 GABA in the endocrine pancreas: its putative role as an islet-cell paracrine-signalling molecule. J Gen Physiol 123:185-190
    • (2004) J Gen Physiol , vol.123 , pp. 185-190
    • Franklin, I.K.1    Wollheim, C.B.2
  • 56
    • 0242432598 scopus 로고    scopus 로고
    • Intra-islet somatostatin regulates glucagon release via type 2 somatostatin receptors in rats
    • Cejvan K, Coy DH, Efendic S 2003 Intra-islet somatostatin regulates glucagon release via type 2 somatostatin receptors in rats. Diabetes 52:1176-1181
    • (2003) Diabetes , vol.52 , pp. 1176-1181
    • Cejvan, K.1    Coy, D.H.2    Efendic, S.3
  • 57
    • 0035449109 scopus 로고    scopus 로고
    • Somatostatin inhibits exocytosis in rat pancreatic α-cells by G(i2)-dependent activation of calcineurin and depriming of secretory granules
    • Gromada J, Hoy M, Buschard K, Salehi A, Rorsman P 2001 Somatostatin inhibits exocytosis in rat pancreatic α-cells by G(i2)-dependent activation of calcineurin and depriming of secretory granules. J Physiol 535:519-532
    • (2001) J Physiol , vol.535 , pp. 519-532
    • Gromada, J.1    Hoy, M.2    Buschard, K.3    Salehi, A.4    Rorsman, P.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.