GPI-anchored proteins are organized in submicron domains at the cell surface

Nature

Volumn 394, Issue 6695, 1998, Pages 798-801

  Varma, Rajat ^a   Mayor, Satyajit ^a  

^a TATA INSTITUTE OF FUNDAMENTAL RESEARCH   (India)

Author keywords

[No Author keywords available]

Indexed keywords

ANIMAL CELL; ARTICLE; CELL SURFACE; CHO CELL; ENERGY TRANSFER; NONHUMAN; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN DOMAIN; PROTEIN LIPID INTERACTION; PROTEIN STRUCTURE;

ANIMALS; CARRIER PROTEINS; CELL MEMBRANE; CHO CELLS; CHOLESTEROL; CRICETINAE; ENERGY TRANSFER; FLUORESCEINS; FLUORESCENCE POLARIZATION; FOLIC ACID; GLYCOSYLPHOSPHATIDYLINOSITOLS; LYSINE; RECEPTORS, CELL SURFACE; TRANSFECTION;

ANIMALIA;

EID: 0032552054     PISSN: 00280836     EISSN: None     Source Type: Journal    
DOI: 10.1038/29563     Document Type: Article

References (31)

1. Jacobson, K., Sheets, E. D. & Simson, R. Revisiting the fluid mosaic model of membranes. Science 268, 1441-1442 (1995).
2. Simons, K. & Ikonen, E. Functional rafts in membranes. Nature 387, 569-570 (1997).
3. Harder, T. & Simons, K. Caveolae, DIGs, and the dynamics of sphingolipid-cholesterol microdomains. Curr. Opin. Cell Biol. 9, 534-542 (1997).
4. Weimbs, T., Hui-Low, S., Chapin, S. J. & Mostov, K. E. Apical targeting in polarized cells: there's more afloat than rafts. Trends Cell Biol. 7, 393-399 (1997).
5. Weber, G. Dependence of polarization of the fluorescence on the concentration. Trans. Faraday Soc. 50, 552-555 (1954).
6. Edidin, M. Lipid microdomains in cell surface membranes. Curr. Opin. Struct. Biol. 7, 528-532 (1997).
7. Brown, R. E. Sphingolipid organization in biomembranes: what physical studies of model membranes reveal. J. Cell Sci. 111, 1-9 (1998).
8. Kurzchalia, T. V., Hartmann, E. & Dupree, P. Guilt by insolubility - does a protein's detergent insolubility reflect a caveolar location? Trend's Cell Biol. 5, 187-189 (1995).
9. Mayor, S. & Maxfield, F. R. Insolubility and redistribution of GPI-anchored proteins at the cell surface after detergent treatment. Mol. Biol. Cell 6, 929-944 (1995).
10. McConville, M. J. & Ferguson, M. A. The structure, biosynthesis and function of glycosylated phosphatidylinositols in the parasitic protozoa and higher eukaryotes. Biochem. J. 294, 305-324 (1993).
11. Mayor, S., Rothberg, K. G. & Maxfield, F. R. Sequestration of GPI-anchored proteins in caveolae triggered by cross-linking. Science 264, 1948-1951 (1994).
12. Parton, R. G., Joggerst, B. & Simons, K. Regulated internalization of caveolae. J. Cell Biol. 127, 1199-1215 (1994).
13. Fujimoto, T. GPI-anchored proteins, glycosphingolipids, and sphingomyelin are sequestered to caveolae only after crosslinking. J. Histochem. Cytochem. 44, 929-941 (1996).
14. Brown, D. The tyrosine kinase connection: how GPI-anchored proteins activate T cells. Curr. Opin. Immunol. 5, 349-354 (1993).
15. Griffiths, G. Fine Structure Immunochemistry 1-459 (Springer, Heidelberg, 1993).
16. Simson, R. et al. Structural mosaicism on the submicron scale in the plasma membrane. Biophys. J. 74, 297-308 (1998).
17. Sheets, E. D., Lee, G. M., Simson, R. & Jacobson, K. Transient confinement of a glycosylphosphatidylinositol-anchored protein in the plasma membrane. Biochemistry 36, 12449-12458 (1997).
18. Kenworthy, A. K. & Eddin, M. Searching for 'lipid rafts' in cell membranes using fluorescence resonance energy transfer (FRET) microscopy. Biophys. J. 74, A8 (1998).
19. Matko, J. & Edidin, M. Energy transfer methods for detecting molecular clusters on cell surfaces. Meth. Enzymol. 278, 444-462 (1997).
20. Hannan, L. A., Lisanti, M. P., Rodriguez-Boulan, E. & Edidin, M. Correctly sorted molecules of a GPI-anchored protein are clustered and immobile when they arrive at the apical surface of MDCK cells. J. Cell Biol. 120, 353-358 (1993).
21. Runnels, L. W. & Scarlata, S. F. Theory and application of fluorescence homotranster to melittin oligomerizaiton. Biophys. J. 69, 1569-1583 (1995).
22. Cerneus, D. P., Ueffing, E., Posthuma, G., Strous, G. J. & van der Ende, A. Detergent insolubility of alkaline phosphatase during biosynthetic transport and endocytosis. Role of cholesterol. J. Biol. Chem. 268, 3150-3155 (1993).
23. Hanada, K., Nishijima, M., Akamatsu, Y. & Pagano, R. E. Both sphingolipids and cholesterol participate in the detergent insolubility of alkaline phosphatase, a glycosylphosphatidylinositol-anchored protein, in mammalian membranes. J. Biol. Chem. 270, 6254-6260 (1995).
24. Taraboulos, A. et al. Cholestrol depletion and modification of COOH-terminal targeting sequence of the prion protein inhibit formation of the scrapie isoform. J. Cell Biology. 129, 121-132 (1995).
25. Chang, W.-J., Rothberg, K. G., Kamen, B. A. & Anderson, R. G. W. Lowering cholesterol content of MA104 cells inhibits receptor-mediated transport of folate. J. Cell Biol. 118, 63-69 (1992).
26. Mayor, S., Sabharanjak, S. & Maxfield, F. R. Cholesterol-dependent retention of GPI-anchored proteins in endosomes. EMBO J. (in the press).
27. Stulnig, T. M. et al. Signal transduction via glycosyl phosphatidylinositol-anchored proteins in T cells is inhibited by lowering cellular cholesterol. J. Biol. Chem. 272, 19242-19247 (1997).
28. Yancey, P. G. et al. Cellular cholesterol efflux mediated by cyclodextrins. Demonstration of kinetic pools and mechanism of efflux. J. Biol. Chem. 271, 16026-16034 (1996).
29. Ritter, T. E., Fajardo, O., Matsue, H., Anderson, R. G. & Lacey, S. W. Folate receptor targeted to clathrin-coated pits cannot regulate vitamin uptake. Proc. Natl Acad. Sci. USA 92, 3824-3828 (1995).
30. Friedrichson, T. & Kurzchalia, T. V. Microdomains of GPI-anchored proteins in living cells revealed by crosslinking. Nature 394, 802-805 (1998).
31. Matter, K., Hunziker, W. & Mellman, I. Basolateral sorting of LDL receptor in MDCK cells: the cytoplasmic domain contains two tyrosine-dependent targeting determinants. Cell. 71, 741-753 (1992).