Anti-mycobacterial activity of quinolones. Triazoloquinolones a new class of potent anti-mycobacterial agents

Anti-Infective Agents in Medicinal Chemistry

Volumn 7, Issue 2, 2008, Pages 134-147

  Carta, Antonio ^a   Piras, Sandra ^a   Palomba, Michele ^a   Jabes, Daniela ^b   Molicotti, Paola ^a   Zanetti, Stefania ^a  

^a UNIVERSITY OF SASSARI   (Italy)

^b NeED Pharmaceuticals   (Italy)

Author keywords

Anti mycobacterial activity; Anti tubercular activity; DNA gyrase inhibitors; MDR; Quinolones; SAR analysis; TB; Triazoloquinolones

Indexed keywords

1 CYCLOPROPYL 7 (3 ETHYL 1 PIPERAZINYL) 6 FLUORO 1,4 DIHYDRO 8 METHOXY 4 OXO 3 QUINOLINECARBOXYLIC ACID; 5 AMINO 7 (7 AMINO 5 AZASPIRO[2.4]HEPT 5 YL) 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 8 METHYL 4 OXO 3 QUINOLINECARBOXYLIC ACID; ANTIMYCOBACTERIAL AGENT; CINOXACIN; CIPROFLOXACIN; CLINAFLOXACIN; DNA TOPOISOMERASE (ATP HYDROLYSING); ECENOFLOXACIN; ENOXACIN; FLUMEQUINE; GATIFLOXACIN; GEMIFLOXACIN; GREPAFLOXACIN; LEVOFLOXACIN; LOMEFLOXACIN; MOXIFLOXACIN; NALIDIXIC ACID; NORFLOXACIN; OFLOXACIN; OXOLINIC ACID; PIPEMIDIC ACID; QUINOLINE DERIVED ANTIINFECTIVE AGENT; SITAFLOXACIN; SPARFLOXACIN; TEMAFLOXACIN; TOSUFLOXACIN; TRIAZOQUINOLONE DERIVATIVE; TROVAFLOXACIN; TUBERCULOSTATIC AGENT; UNINDEXED DRUG;

ACTINOBACTERIA; ALLERGIC REACTION; ANTIBACTERIAL ACTIVITY; ANTIBIOTIC RESISTANCE; ARTICLE; ATYPICAL MYCOBACTERIOSIS; BACTERIAL STRAIN; BACTERIUM ISOLATE; CANDIDA ALBICANS; CANDIDA TROPICALIS; DIZZINESS; DRUG ABSORPTION; DRUG CLEARANCE; DRUG EFFICACY; DRUG ERUPTION; DRUG EXCRETION; DRUG HALF LIFE; DRUG INDUCED HEADACHE; DRUG SCREENING; DRUG SYNTHESIS; DRUG TOLERABILITY; DRUG WITHDRAWAL; ENZYME INHIBITION; GASTROINTESTINAL SYMPTOM; HUMAN; HYPOGLYCEMIA; LIVER TOXICITY; LUNG TUBERCULOSIS; MINIMUM INHIBITORY CONCENTRATION; MORTALITY; MULTIDRUG RESISTANCE; MYCOBACTERIUM INTRACELLULARE AVIUM; NEUROLOGIC DISEASE; NONHUMAN; PHOTOTOXICITY; PRURITUS; QT PROLONGATION; SALMONELLA TYPHIMURIUM; STAPHYLOCOCCUS AUREUS; STRUCTURE ACTIVITY RELATION;

EID: 44449127718     PISSN: 18715214     EISSN: None     Source Type: Journal    
DOI: 10.2174/187152108783954641     Document Type: Article

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