Synthesis and antibacterial activity of N-[2-[5-(methylthio)thiophen-2-yl]-2-oxoethyl] and N-[2-[5-(methylthio)thiophen-2-yl]-2-(oxyimino)ethyl]piperazinylquinolone derivatives

Bioorganic and Medicinal Chemistry

Volumn 14, Issue 10, 2006, Pages 3421-3427

  Foroumadi, Alireza ^a,d   Oboudiat, Mehdi ^b   Emami, Saeed ^c   Karimollah, Alireza ^b   Saghaee, Lotfollah ^b   Moshafi, Mohammad Hassan ^d   Shafiee, Abbas ^a  

^a TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^d KERMAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

In vitro antibacterial activity; N Substituted piperazinylquinolones; Quinolones

Indexed keywords

1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 [5 (METHYLTHIO)THIOPHEN 2 YL] 2 (BENZYLOXYIMINO)ETHYL]PIPERAZIN 1 YL] 4 OXO 3 QUINOLONE CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 [5 (METHYLTHIO)THIOPHEN 2 YL] 2 HYDROXYIMINOETHYL]PIPERAZIN 1 YL] 4 OXO 3 QUINOLONE CARBOXYLIC ACID; 1 CYCLOPROPYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 [5 (METHYLTHIO)THIOPHEN 2 YL] 2 METHOXYIMINOETHYL]PIPERAZIN 1 YL] 4 OXO 3 QUINOLONE CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 [5 (METHYLTHIO)THIOPEN 2 YL] 2 HYDROXYIMINOETHYL)PIPERAZIN 1 YL] 4 OXO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 [5 (METHYLTHIO)THIOPEN 2 YL] 2 HYDROXYIMINOETHYL]PIPERAZIN 1 YL] 4 OXO 3 QUINOLONE CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 [5 (METHYLTHIO)THIOPHEN 2 YL] 2 (BENZYLOXYIMINO)ETHYL]PIPERAZIN 1 YL] 4 OXO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 [5 (METHYLTHIO)THIOPHEN 2 YL] 2 (BENZYLOXYIMINO)ETHYL]PIPERAZIN 1 YL] 4 OXO 3 QUINOLONE CARBOXYLIC ACID; 1 ETHYL 6 FLUORO 1,4 DIHYDRO 7 [4 [2 [5 (METHYLTHIO)THIOPHEN 2 YL] 2 METHOXYIMINOETHYL]PIPERAZIN 1 YL] 4 OXO 1,8 NAPHTHYRIDINE 3 CARBOXYLIC ACID; CARBOXYLIC ACID; N [2 (5 (METHYLTHIO)THIOPHEN 2 YL) 2 OXOETHYL]PIPERAZINYLQUINOLONE; N [2 [5 (METHYLTHIO)THIOPHEN 2 YL] 2 (OXYIMINO)ETHYL]PIPERAZINYLQUINOLONE; QUINOLONE DERIVATIVE; UNCLASSIFIED DRUG;

ANTIBACTERIAL ACTIVITY; ARTICLE; DRUG POTENCY; DRUG SYNTHESIS; GRAM NEGATIVE BACTERIUM; GRAM POSITIVE BACTERIUM; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS;

ANTI-BACTERIAL AGENTS; CIPROFLOXACIN; MICROBIAL SENSITIVITY TESTS; MOLECULAR STRUCTURE; PIPERAZINES; QUINOLONES; STAPHYLOCOCCUS; THIOPHENES;

NEGIBACTERIA; POSIBACTERIA; STAPHYLOCOCCUS; STAPHYLOCOCCUS AUREUS; STAPHYLOCOCCUS EPIDERMIDIS;

EID: 33645893790     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bmc.2005.12.058     Document Type: Article

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