Fine affinity discrimination by yeast surface display and flow cytometry

Biotechnology Progress

Volumn 16, Issue 1, 2000, Pages 31-37

  VanAntwerp, Jennifer J ^a   Wittrup, K Dane ^a  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FLOW CYTOMETRY; SACCHAROMYCES CEREVISIAE; YEAST SURFACE DISPLAY;

AFFINITY LABELING; CLONE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; FLUORESCENT LABELING; LYSOZYME; SACCHAROMYCES CEREVISIAE; YEAST SURFACE DISPLAY;

ANTIBODIES; ANTIGENS; CELLS; CLONING; PROTEINS; PURIFICATION;

YEAST;

ANIMALS; ANTIBODIES, MONOCLONAL; ANTIBODY AFFINITY; BIOTECHNOLOGY; CHICKENS; DIRECTED MOLECULAR EVOLUTION; DRUG STABILITY; FLOW CYTOMETRY; IMMUNOGLOBULIN VARIABLE REGION; MICE; MURAMIDASE; MUTATION; PROTEIN BINDING; SACCHAROMYCES CEREVISIAE;

EUKARYOTA; SACCHAROMYCES CEREVISIAE;

EID: 0033976101     PISSN: 87567938     EISSN: None     Source Type: Journal    
DOI: 10.1021/bp990133s     Document Type: Article

References (26)

1. Bhat, T. N.; Bentley, G. A.; Boulot, G.; Greene, M. I.; Tello, D.; Dall'Acqua, W.; Souchon, H.; Schwarz, F. P.; Mariuzza, R. A.; Poljak, R. J. Bound water molecules and conformational stabilization help mediate an antigen-antibody association. Proc. Natl. Acad. Sci. U.S.A 1994, 91, 1089-93.
2. Boder, E. T.; Wittrup, K. D. Yeast surface display for screening combinatorial polypeptide libraries. Nat. Biotechnol. 1997, 15, 553-7.
3. Boder, E. T.; Wittrup, K. D. Optimal screening of surface-displayed polypeptide libraries. Biotechnol. Prog. 1998, 14, 55-62.
4. Dall'Acqua, W.; Goldman, E. R.; Eisenstein, E.; Mariuzza, R. A. A mutational analysis of the binding of two different proteins to the same antibody. Biochemistry 1996, 35, 9667-76.
5. Daugherty, P. S.; Chen, G.; Olsen, M. J.; Iverson, B. L.; Georgiou, G. Antibody affinity maturation using bacterial surface display. Protein Eng. 1998, 11, 825-32.
6. Georgiou, G.; Stathopoulos, C.; Daugherty, P. S.; Nayak, A. R.; Iverson, B. L.; Curtiss, R., 3rd. Display of heterologous proteins on the surface of microorganisms: from the screening of combinatorial libraries to live recombinant vaccines. Nat. Biotechnol. 1997, 15, 29-34.
7. Goldbaum, F. A.; Schwarz, F. P.; Eisenstein, E.; Cauerhff, A.; Mariuzza, R. A.; Poljak, R. J. The effect of water activity on the association constant and the enthalpy of reaction between lysozyme and the specific antibodies D1.3 and D44.1. J. Mol. Recognit. 1996, 9, 6-12.
8. Griffiths, A. D.; Duncan, A. R. Strategies for selection of antibodies by phage display. Curr. Opin. Biotechnol. 1998, 9, 102-8.
9. Hawkins, R. E.; Russell, S. J.; Baier, M.; Winter, G. The contribution of contact and noncontact residues of antibody in the affinity of binding to antigen. The interaction of mutant D1.3 antibodies with lysozyme. J. Mol. Biol. 1993, 234, 958-64.
10. Hoogenboom, H. R.; de Bruine, A. P.; Hufton, S. E.; Hoet, R. M.; Arends, J. W.; Roovers, R. C. Antibody phage display technology and its applications. Immunotechnology 1998, 4, 1-20.
11. Kieke, M. C.; Cho, B. K.; Boder, E. T.; Kranz, D. M.; Wittrup, K. D. Isolation of anti-T cell receptor scFv mutants by yeast surface display. Protein Eng. 1997, 10, 1303-10.
12. Kieke, M. C.; Shusta, E. V.; Boder, E. T.; Teyton, L.; Wittrup, K. D.; Kranz, D. M. Selection of functional T cell receptor mutants from a yeast surface-display library. Proc. Natl. Acad. Sci. U.S.A. 1999, in press.
13. Kretzschmar, T.; Zimmermann, C.; Geiser, M. Selection procedures for nonmatured phage antibodies: a quantitative comparison and optimization strategies. Anal. Biochem. 1995, 224, 413-9.
14. Malmborg, A. C.; Soderlind, E.; Frost, L.; Borrebaeck, C. A. Selective phage infection mediated by epitope expression on F pilus. J. Mol. Biol. 1997, 273, 544-51.
15. Rader, C.; Barbas, C. F., 3rd. Phage display of combinatorial antibody libraries. Curr. Opin. Biotechnol. 1997, 8, 503-8.
16. Sandberg, W. S.; Terwilliger, T. C. Engineering multiple properties of a protein bv combinatorial mutagenesis. Proc. Natl. Acad. Sci. U.S.A. 1993, 90, 8367-71.
17. Schier, R.; Bye, J.; Apell, G.; McCall, A.; Adams, G. P.; Malmqvist, M.; Weiner, L. M.; Marks, J. D. Isolation of high-affinity monomeric human anti-c-erbB-2 single chain Fv using affinity-driven selection. J. Mol. Biol. 1996, 255, 28-43.
18. Shusta, E. V.; Raines, R. T.; Pluckthun, A.; Wittrup, K. D. Increasing the secretory capacity of Saccharomyces cerevisiae for production of single-chain antibody fragments. Nat. Biotechnol. 1998, 16, 773-7.
19. Shusta, E. V.; VanAntwerp, J, J.; Wittrup, K. D. Biosynthetic polypeptide libraries. Curr. Opin. Biotechnol. 1999, 10, 117-22.
20. Sikorski, R. S.; Hieter, P. A system of shuttle vectors and yeast host strains designed for efficient manipulation of DNA in Saccharomyces cerevisiae. Genetics 1989, 122, 19-27.
21. Spada, S.; Krebber, C.; Pluckthun, A. Selectively infective phages (SIP). Biol. Chem. 1997, 378, 445-56.
22. Stemmer, W. P. DNA shuffling by random fragmentation and reassembly: in vitro recombination for molecular evolution. Proc. Natl. Acad. Sci. U.S.A. 1994a, 91, 10747-51.
23. Stemmer, W. P. Rapid evolution of a protein in vitro by DNA shuffling [see comments]. Nature 1994b, 370, 389-91.
24. VanAntwerp, J. J.; Wittrup, K. D. Thermodynamic characterization of D1.3 and a higher-affinity mutant. J. Mol. Recognit. 1998, 11, 10-13.
25. Wilson, D. R.; Finlay, B. B. Phage display: applications, innovations, and issues in phage and host biology. Can. J. Microbiol. 1998, 44, 313-29.
26. Yelton, D. E.; Rosok, M. J.; Crux, G.; Cosand, W. L.; Bajorath, J.; Hellstrom, I.; Hellstrom, K. E.; Huse, W. D.; Glaser, S. M. Affinity maturation of the BR96 anti-carcinoma antibody by codon-based mutagenesis. J. Immunol. 1995, 155, 1994-2004.