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Volumn 60, Issue 1, 2008, Pages 15-29

Manipulation of androgens and alterations in the androgen receptor axis in prostate cancer

Author keywords

Gene amplification; Prostatic neoplasms; Receptors, androgen

Indexed keywords

ANDROGEN; ANDROGEN RECEPTOR; DUTASTERIDE; FINASTERIDE; HYDROXYFLUTAMIDE; STEROID 5ALPHA REDUCTASE INHIBITOR;

EID: 43949123277     PISSN: 03932249     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (4)

References (131)
  • 1
    • 0016359646 scopus 로고
    • Steroid 5alpha-reductase deficiency in man: An inherited form of male pseudohermaphroditism
    • Imperato-McGinley J, Guerrero L, Gautier T, Peterson RE. Steroid 5alpha-reductase deficiency in man: an inherited form of male pseudohermaphroditism. Science 1974;186:1213-5.
    • (1974) Science , vol.186 , pp. 1213-1215
    • Imperato-McGinley, J.1    Guerrero, L.2    Gautier, T.3    Peterson, R.E.4
  • 3
    • 0014429464 scopus 로고
    • The conversion of testosterone to 5-alpha-androstan-17-beta-ol-3-one by rat prostate in vivo and in vitro
    • Bruchovsky N, Wilson JD. The conversion of testosterone to 5-alpha-androstan-17-beta-ol-3-one by rat prostate in vivo and in vitro. J Biol Chem 1968;243:2012-21.
    • (1968) J Biol Chem , vol.243 , pp. 2012-2021
    • Bruchovsky, N.1    Wilson, J.D.2
  • 4
    • 0017618135 scopus 로고
    • Estrogen use and cancer risk
    • Lipsett MB. Estrogen use and cancer risk. J Am Med Assoc 1977;237:1112-5.
    • (1977) J Am Med Assoc , vol.237 , pp. 1112-1115
    • Lipsett, M.B.1
  • 5
    • 43949117888 scopus 로고    scopus 로고
    • Klein EA, Platz EA, Thompson IM. Epidemiology, Etiology, and Prevention of Prostate Cancer. In: Wein AJ, editor. Campbell-Walsh Urology. 9th ed. Philadelphia: Saunders Elsevier; 2007. p. 2854-73.
    • Klein EA, Platz EA, Thompson IM. Epidemiology, Etiology, and Prevention of Prostate Cancer. In: Wein AJ, editor. Campbell-Walsh Urology. 9th ed. Philadelphia: Saunders Elsevier; 2007. p. 2854-73.
  • 6
    • 0015370976 scopus 로고
    • Studies on prostatic cancer. I. The effect of castration, of estrogen and androgen injection on serum phosphatases in metastatic carcinoma of the prostate
    • Huggins C, Hodges CV. Studies on prostatic cancer. I. The effect of castration, of estrogen and androgen injection on serum phosphatases in metastatic carcinoma of the prostate. CA Cancer J Clin 1972;22:232-40.
    • (1972) CA Cancer J Clin , vol.22 , pp. 232-240
    • Huggins, C.1    Hodges, C.V.2
  • 7
    • 0027493481 scopus 로고
    • The stringency and magnitude of androgen-specific gene activation are combinatorial functions of receptor and nonreceptor binding site sequences
    • Adler AJ, Scheller A, Robins DM. The stringency and magnitude of androgen-specific gene activation are combinatorial functions of receptor and nonreceptor binding site sequences. Mol Cell Biol 1993;13:6326-35.
    • (1993) Mol Cell Biol , vol.13 , pp. 6326-6335
    • Adler, A.J.1    Scheller, A.2    Robins, D.M.3
  • 9
    • 0001548433 scopus 로고    scopus 로고
    • Two androgen response elements in the androgen receptor coding region are required for cell-specific up-regulation of receptor messenger RNA
    • Dai JL, Burnstein KL. Two androgen response elements in the androgen receptor coding region are required for cell-specific up-regulation of receptor messenger RNA. Mol Endocrinol 1996;10:1582-94.
    • (1996) Mol Endocrinol , vol.10 , pp. 1582-1594
    • Dai, J.L.1    Burnstein, K.L.2
  • 10
    • 3142739478 scopus 로고    scopus 로고
    • Identification of an androgen response element in intron 8 of the sterol regulatory element-binding protein cleavage-activating protein gene allowing direct regulation by the androgen receptor
    • Heemers H, Verrijdt G, Organe S, Claessens F, Heyns W, Verhoeven G et al. Identification of an androgen response element in intron 8 of the sterol regulatory element-binding protein cleavage-activating protein gene allowing direct regulation by the androgen receptor. J Biol Chem 2004;279:30880-7.
    • (2004) J Biol Chem , vol.279 , pp. 30880-30887
    • Heemers, H.1    Verrijdt, G.2    Organe, S.3    Claessens, F.4    Heyns, W.5    Verhoeven, G.6
  • 12
    • 11244255408 scopus 로고    scopus 로고
    • Identification of a novel functional androgen response element within hPar1 promoter: Implications to prostate cancer progression
    • Salah Z, Maoz M, Cohen I, Pizov G, Pode D, Runge MS et al. Identification of a novel functional androgen response element within hPar1 promoter: implications to prostate cancer progression. Faseb J 2005;19:62-72.
    • (2005) Faseb J , vol.19 , pp. 62-72
    • Salah, Z.1    Maoz, M.2    Cohen, I.3    Pizov, G.4    Pode, D.5    Runge, M.S.6
  • 13
    • 33746623315 scopus 로고    scopus 로고
    • Molecular regulation of androgen action in prostate cancer
    • Dehm SM, Tindall DJ. Molecular regulation of androgen action in prostate cancer. J Cell Biochem 2006;99:333-44.
    • (2006) J Cell Biochem , vol.99 , pp. 333-344
    • Dehm, S.M.1    Tindall, D.J.2
  • 14
    • 29344441929 scopus 로고    scopus 로고
    • Androgens regulate the immune/inflammatory response and cell survival pathways in rat ventral prostate epithelial cells
    • Asirvatham AJ, Schmidt M, Gao B, Chaudhary J. Androgens regulate the immune/inflammatory response and cell survival pathways in rat ventral prostate epithelial cells. Endocrinology 2006;147:257-71.
    • (2006) Endocrinology , vol.147 , pp. 257-271
    • Asirvatham, A.J.1    Schmidt, M.2    Gao, B.3    Chaudhary, J.4
  • 15
    • 0033638079 scopus 로고    scopus 로고
    • Plasma androgens, IGF-1, body size, and prostate cancer risk: A synthetic review
    • Kaaks R, Lukanova A, Sommersberg B. Plasma androgens, IGF-1, body size, and prostate cancer risk: a synthetic review. Prostate Cancer Prostatic Dis 2000;3:157-72.
    • (2000) Prostate Cancer Prostatic Dis , vol.3 , pp. 157-172
    • Kaaks, R.1    Lukanova, A.2    Sommersberg, B.3
  • 16
    • 0033614366 scopus 로고    scopus 로고
    • FGF8 over-expression in prostate cancer is associated with decreased patient survival and persists in androgen independent disease
    • Dorkin TJ, Robinson MC, Marsh C, Bjartell A, Neal DE, Leung HY. FGF8 over-expression in prostate cancer is associated with decreased patient survival and persists in androgen independent disease. Oncogene 1999;18:2755-61.
    • (1999) Oncogene , vol.18 , pp. 2755-2761
    • Dorkin, T.J.1    Robinson, M.C.2    Marsh, C.3    Bjartell, A.4    Neal, D.E.5    Leung, H.Y.6
  • 17
    • 15444349656 scopus 로고    scopus 로고
    • High frequency of fibroblast growth factor (FGF) 8 expression in clinical prostate cancers and breast tissues, immunohistochemically demonstrated by a newly established neutralizing monoclonal antibody against FGF 8
    • Tanaka A, Furuya A, Yamasaki M, Hanai N, Kuriki K, Kamiakito T et al. High frequency of fibroblast growth factor (FGF) 8 expression in clinical prostate cancers and breast tissues, immunohistochemically demonstrated by a newly established neutralizing monoclonal antibody against FGF 8. Cancer Res 1998;58:2053-6.
    • (1998) Cancer Res , vol.58 , pp. 2053-2056
    • Tanaka, A.1    Furuya, A.2    Yamasaki, M.3    Hanai, N.4    Kuriki, K.5    Kamiakito, T.6
  • 19
    • 22444438599 scopus 로고    scopus 로고
    • The androgen receptor directly targets the cellular Fas/FasL-associated death domain protein-like inhibitory protein gene to promote the androgen-independent growth of prostate cancer cells
    • Gao S, Lee P, Wang H, Gerald W, Adler M, Zhang L et al The androgen receptor directly targets the cellular Fas/FasL-associated death domain protein-like inhibitory protein gene to promote the androgen-independent growth of prostate cancer cells. Mol Endocrinol 2005;19:1792-802.
    • (2005) Mol Endocrinol , vol.19 , pp. 1792-1802
    • Gao, S.1    Lee, P.2    Wang, H.3    Gerald, W.4    Adler, M.5    Zhang, L.6
  • 20
    • 33745204446 scopus 로고    scopus 로고
    • Androgen receptor and prostate apoptosis response factor-4 target the c-FLIP gene to determine survival and apoptosis in the prostate gland
    • Gao S, Wang H, Lee P, Melamed J, Li CX, Zhang F et al Androgen receptor and prostate apoptosis response factor-4 target the c-FLIP gene to determine survival and apoptosis in the prostate gland. J Mol Endocrinol 2006;36:463-83.
    • (2006) J Mol Endocrinol , vol.36 , pp. 463-483
    • Gao, S.1    Wang, H.2    Lee, P.3    Melamed, J.4    Li, C.X.5    Zhang, F.6
  • 21
    • 27144458128 scopus 로고    scopus 로고
    • Androgen regulates apoptosis induced by TNFR family ligands via multiple signaling pathways in LNCaP
    • Rokhlin OW, Taghiyev AF, Guseva NV, Glover RA, Chumakov PM, Kravchenko JE et al. Androgen regulates apoptosis induced by TNFR family ligands via multiple signaling pathways in LNCaP. Oncogene 2005;24:6773-84.
    • (2005) Oncogene , vol.24 , pp. 6773-6784
    • Rokhlin, O.W.1    Taghiyev, A.F.2    Guseva, N.V.3    Glover, R.A.4    Chumakov, P.M.5    Kravchenko, J.E.6
  • 22
  • 23
    • 15744363978 scopus 로고    scopus 로고
    • Delayed dark adaptation in 11-cis-retinol dehydrogenase-deficient mice: A role of RDH11 in visual processes in vivo
    • Kim TS, Maeda A, Maeda T, Heinlein C, Kedishvili N, Palczewski K et al Delayed dark adaptation in 11-cis-retinol dehydrogenase-deficient mice: a role of RDH11 in visual processes in vivo. J Biol Chem 2005;280:8694-704.
    • (2005) J Biol Chem , vol.280 , pp. 8694-8704
    • Kim, T.S.1    Maeda, A.2    Maeda, T.3    Heinlein, C.4    Kedishvili, N.5    Palczewski, K.6
  • 24
    • 33749870551 scopus 로고    scopus 로고
    • TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions
    • Cerveira N, Ribeiro FR, Peixoto A, Costa V, Henrique R, Jeronimo C et al. TMPRSS2-ERG gene fusion causing ERG overexpression precedes chromosome copy number changes in prostate carcinomas and paired HGPIN lesions. Neoplasia 2006;8:826-32.
    • (2006) Neoplasia , vol.8 , pp. 826-832
    • Cerveira, N.1    Ribeiro, F.R.2    Peixoto, A.3    Costa, V.4    Henrique, R.5    Jeronimo, C.6
  • 25
    • 33845329915 scopus 로고    scopus 로고
    • TMPRSS2:ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer
    • Hermans KG, van Marion R, van Dekken H, Jenster G, van Weerden WM, Trapman J. TMPRSS2:ERG fusion by translocation or interstitial deletion is highly relevant in androgen-dependent prostate cancer, but is bypassed in late-stage androgen receptor-negative prostate cancer. Cancer Res 2006;66:10658-63.
    • (2006) Cancer Res , vol.66 , pp. 10658-10663
    • Hermans, K.G.1    van Marion, R.2    van Dekken, H.3    Jenster, G.4    van Weerden, W.M.5    Trapman, J.6
  • 26
    • 0030724993 scopus 로고    scopus 로고
    • Genes regulated by androgen in the rat ventral prostate
    • Wang Z, Tufts R, Haleem R, Cai X. Genes regulated by androgen in the rat ventral prostate. Proc Natl Acad Sci U S A 1997;94:12999-3004.
    • (1997) Proc Natl Acad Sci U S A , vol.94 , pp. 12999-13004
    • Wang, Z.1    Tufts, R.2    Haleem, R.3    Cai, X.4
  • 27
    • 33846594230 scopus 로고    scopus 로고
    • Apoptosis induction and growth suppression by U19/Eaf2 is mediated through its ELL-binding domain
    • Hahn J, Xiao W, Jiang F, Simone F, Thirman MJ, Wang Z. Apoptosis induction and growth suppression by U19/Eaf2 is mediated through its ELL-binding domain. Prostate 2007;67:146-53.
    • (2007) Prostate , vol.67 , pp. 146-153
    • Hahn, J.1    Xiao, W.2    Jiang, F.3    Simone, F.4    Thirman, M.J.5    Wang, Z.6
  • 28
    • 0037443468 scopus 로고    scopus 로고
    • ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties
    • Simone F, Luo RT, Polak PE, Kaberlein JJ, Thirman MJ. ELL-associated factor 2 (EAF2), a functional homolog of EAF1 with alternative ELL binding properties. Blood 2003;101:2355-62.
    • (2003) Blood , vol.101 , pp. 2355-2362
    • Simone, F.1    Luo, R.T.2    Polak, P.E.3    Kaberlein, J.J.4    Thirman, M.J.5
  • 29
    • 29344449076 scopus 로고    scopus 로고
    • ELL binding regulates U19/Eaf2 intracellular localization, stability, and transactivation
    • Xiao W, Jiang F, Wang Z. ELL binding regulates U19/Eaf2 intracellular localization, stability, and transactivation. Prostate 2006;66:1-12.
    • (2006) Prostate , vol.66 , pp. 1-12
    • Xiao, W.1    Jiang, F.2    Wang, Z.3
  • 30
    • 43949102520 scopus 로고    scopus 로고
    • U19/Eaf2 knockout causes lung adenocarcinoma, B-cell lymphoma, hepatocellular carcinoma and prostatic intraepithelial neoplasia
    • Epub ahead of print
    • Xiao W, Zhang Q, Habermacher G, Yang X, Zhang AY, Cai X et al. U19/Eaf2 knockout causes lung adenocarcinoma, B-cell lymphoma, hepatocellular carcinoma and prostatic intraepithelial neoplasia. Oncogene 2007 [Epub ahead of print].
    • (2007) Oncogene
    • Xiao, W.1    Zhang, Q.2    Habermacher, G.3    Yang, X.4    Zhang, A.Y.5    Cai, X.6
  • 31
    • 0041633811 scopus 로고    scopus 로고
    • Suppression of prostate tumor growth by U19, a novel testosterone-regulated apoptosis inducer
    • Xiao W, Zhang Q, Jiang F, Pins M, Kozlowski JM, Wang Z. Suppression of prostate tumor growth by U19, a novel testosterone-regulated apoptosis inducer. Cancer Res 2003;63:4698-704.
    • (2003) Cancer Res , vol.63 , pp. 4698-4704
    • Xiao, W.1    Zhang, Q.2    Jiang, F.3    Pins, M.4    Kozlowski, J.M.5    Wang, Z.6
  • 32
    • 0343673830 scopus 로고    scopus 로고
    • Differential regulation of testosterone vs. 5alpha-dihydrotestosterone by selective androgen response elements
    • Hsiao PW, Thin TH, Lin DL, Chang C. Differential regulation of testosterone vs. 5alpha-dihydrotestosterone by selective androgen response elements. Mol Cell Biochem 2000;206:169-75.
    • (2000) Mol Cell Biochem , vol.206 , pp. 169-175
    • Hsiao, P.W.1    Thin, T.H.2    Lin, D.L.3    Chang, C.4
  • 33
    • 0034743524 scopus 로고    scopus 로고
    • Inhibition of 5alha-reductase in rat prostate reveals differential regulation of androgen-response gene expression by testosterone and dihydrotestosterone
    • Dadras SS, Cai X, Abasolo I, Wang Z. Inhibition of 5alha-reductase in rat prostate reveals differential regulation of androgen-response gene expression by testosterone and dihydrotestosterone. Gene Expr 2001;9:183-94.
    • (2001) Gene Expr , vol.9 , pp. 183-194
    • Dadras, S.S.1    Cai, X.2    Abasolo, I.3    Wang, Z.4
  • 34
    • 2042453326 scopus 로고    scopus 로고
    • Bone loss and the evolving role of bisphosphonate therapy in prostate cancer
    • Higano CS. Bone loss and the evolving role of bisphosphonate therapy in prostate cancer. Urol Oncol 2003;21:392-8.
    • (2003) Urol Oncol , vol.21 , pp. 392-398
    • Higano, C.S.1
  • 35
    • 2942584859 scopus 로고    scopus 로고
    • Intermittent androgen deprivation therapy for prostate cancer
    • Rashid MH, Chaudhary UB. Intermittent androgen deprivation therapy for prostate cancer. Oncologist 2004;9:295-301.
    • (2004) Oncologist , vol.9 , pp. 295-301
    • Rashid, M.H.1    Chaudhary, U.B.2
  • 36
    • 0141957526 scopus 로고    scopus 로고
    • Andropause: Symptom management for prostate cancer patients treated with hormonal ablation
    • Thompson CA, Shanafelt TD, Loprinzi CL. Andropause: symptom management for prostate cancer patients treated with hormonal ablation. Oncologist 2003;8:474-87.
    • (2003) Oncologist , vol.8 , pp. 474-487
    • Thompson, C.A.1    Shanafelt, T.D.2    Loprinzi, C.L.3
  • 38
    • 0027416692 scopus 로고
    • Effects of intermittent androgen suppression on androgen-dependent tumors. Apoptosis and serum prostate-specific antigen
    • Akakura K, Bruchovsky N, Goldenberg SL, Rennie PS, Buckley AR, Sullivan LD. Effects of intermittent androgen suppression on androgen-dependent tumors. Apoptosis and serum prostate-specific antigen. Cancer 1993;71:2782-90.
    • (1993) Cancer , vol.71 , pp. 2782-2790
    • Akakura, K.1    Bruchovsky, N.2    Goldenberg, S.L.3    Rennie, P.S.4    Buckley, A.R.5    Sullivan, L.D.6
  • 39
    • 0025684708 scopus 로고
    • Loss of androgen dependence is associated with an increase in tumorigenic stem cells and resistance to cell-death genes
    • Rennie PS, Bruchovsky N, Coldman AJ. Loss of androgen dependence is associated with an increase in tumorigenic stem cells and resistance to cell-death genes. J Steroid Biochem Mol Biol 1990;37:843-7.
    • (1990) J Steroid Biochem Mol Biol , vol.37 , pp. 843-847
    • Rennie, P.S.1    Bruchovsky, N.2    Coldman, A.J.3
  • 40
    • 0026602518 scopus 로고
    • Serum prostate specific antigen levels in mice bearing human prostate LNCaP tumors are determined by tumor volume and endocrine and growth factors
    • Gleave ME, Hsieh JT, Wu HC, von Eschenbach AC, Chung LW. Serum prostate specific antigen levels in mice bearing human prostate LNCaP tumors are determined by tumor volume and endocrine and growth factors. Cancer Res 1992;52:1598-605.
    • (1992) Cancer Res , vol.52 , pp. 1598-1605
    • Gleave, M.E.1    Hsieh, J.T.2    Wu, H.C.3    von Eschenbach, A.C.4    Chung, L.W.5
  • 41
    • 2342537793 scopus 로고    scopus 로고
    • Understanding treatments for bone loss and bone metastases in patients with prostate cancer: A practical review and guide for the clinician
    • Higano CS. Understanding treatments for bone loss and bone metastases in patients with prostate cancer: a practical review and guide for the clinician. Urol Clin North Am 2004;31:331-52.
    • (2004) Urol Clin North Am , vol.31 , pp. 331-352
    • Higano, C.S.1
  • 42
    • 1642461538 scopus 로고    scopus 로고
    • Cognitive changes associated with supplementation of testosterone or dihydrotestosterone in mildly hypogonadal men: A preliminary report
    • Cherrier MM, Craft S, Matsumoto AH. Cognitive changes associated with supplementation of testosterone or dihydrotestosterone in mildly hypogonadal men: a preliminary report. J Androl 2003;24:568-76.
    • (2003) J Androl , vol.24 , pp. 568-576
    • Cherrier, M.M.1    Craft, S.2    Matsumoto, A.H.3
  • 43
    • 3042600342 scopus 로고    scopus 로고
    • One year follow-up study of the association between chemical castration, sex hormones, beta-amyloid, memory and depression in men
    • Almeida OP, Waterreus A, Spry N, Flicker L, Martins RN. One year follow-up study of the association between chemical castration, sex hormones, beta-amyloid, memory and depression in men. Psychoneuroendocrinology 2004;29:1071-81.
    • (2004) Psychoneuroendocrinology , vol.29 , pp. 1071-1081
    • Almeida, O.P.1    Waterreus, A.2    Spry, N.3    Flicker, L.4    Martins, R.N.5
  • 45
    • 44949231272 scopus 로고    scopus 로고
    • Conti PD, Atallah AN, Arruda H, Soares BG, El Dib RP, Wilt TJ. Intermittent versus continuous androgen suppression for prostatic cancer. Cochrane database of systematic reviews (Online) 2007:CD005009.
    • Conti PD, Atallah AN, Arruda H, Soares BG, El Dib RP, Wilt TJ. Intermittent versus continuous androgen suppression for prostatic cancer. Cochrane database of systematic reviews (Online) 2007:CD005009.
  • 46
    • 43949111123 scopus 로고    scopus 로고
    • Miller K, Steiner U, Lingnau A, Keilholz U, Witzsch U, Haider A et al. Randomized prospective study of intermittent versus continous androgen suppression in advanced prostate cancer. J Clin Oncol 2007; ASCO Annual Meeting Proceedings. 2007;25:18S(Suppl):238s.
    • Miller K, Steiner U, Lingnau A, Keilholz U, Witzsch U, Haider A et al. Randomized prospective study of intermittent versus continous androgen suppression in advanced prostate cancer. J Clin Oncol 2007; ASCO Annual Meeting Proceedings. 2007;25:18S(Suppl):238s.
  • 47
    • 37349107226 scopus 로고    scopus 로고
    • Type 1 and type 2 5alpha-reductase expression in the development and progression of prostate cancer
    • Thomas LN, Douglas RC, Lazier CB, Too CK, Rittmaster RS, Tindall DJ. Type 1 and type 2 5alpha-reductase expression in the development and progression of prostate cancer. Eur Urol 2008;53:244-52.
    • (2008) Eur Urol , vol.53 , pp. 244-252
    • Thomas, L.N.1    Douglas, R.C.2    Lazier, C.B.3    Too, C.K.4    Rittmaster, R.S.5    Tindall, D.J.6
  • 48
    • 33645341444 scopus 로고    scopus 로고
    • Enhancement of intermittent androgen ablation by "off-cycle" maintenance with finasteride in LNCaP prostate cancer xenograft model
    • Eggener SE, Stern JA, Jain PM, Oram S, Ai J, Cai X et al. Enhancement of intermittent androgen ablation by "off-cycle" maintenance with finasteride in LNCaP prostate cancer xenograft model. Prostate 2006;66:495-502.
    • (2006) Prostate , vol.66 , pp. 495-502
    • Eggener, S.E.1    Stern, J.A.2    Jain, P.M.3    Oram, S.4    Ai, J.5    Cai, X.6
  • 49
    • 33645970181 scopus 로고    scopus 로고
    • Intermittent use of testosterone inactivating pharmaceuticals using finasteride prolongs the time off period
    • Scholz MC, Jennrich RI, Strum SB, Johnson HJ, Guess BW, Lam RY. Intermittent use of testosterone inactivating pharmaceuticals using finasteride prolongs the time off period. J Urol 2006;175:1673-8.
    • (2006) J Urol , vol.175 , pp. 1673-1678
    • Scholz, M.C.1    Jennrich, R.I.2    Strum, S.B.3    Johnson, H.J.4    Guess, B.W.5    Lam, R.Y.6
  • 50
    • 0028220323 scopus 로고
    • Increased androgen receptor activity and altered c-myc expression in prostate cancer cells after long-term androgen deprivation
    • Kokontis J, Takakura K, Hay N, Liao S. Increased androgen receptor activity and altered c-myc expression in prostate cancer cells after long-term androgen deprivation. Cancer Res 1994;54:1566-73.
    • (1994) Cancer Res , vol.54 , pp. 1566-1573
    • Kokontis, J.1    Takakura, K.2    Hay, N.3    Liao, S.4
  • 52
  • 53
    • 0033930522 scopus 로고    scopus 로고
    • Inhibition of LncaP prostate cancer cells by means of androgen receptor antisense oligonucleotides
    • Eder IE, Culig Z, Ramoner R, Thurnher M, Putz T, Nessler-Menardi C et al. Inhibition of LncaP prostate cancer cells by means of androgen receptor antisense oligonucleotides. Cancer Gene Ther 2000;7:997-1007.
    • (2000) Cancer Gene Ther , vol.7 , pp. 997-1007
    • Eder, I.E.1    Culig, Z.2    Ramoner, R.3    Thurnher, M.4    Putz, T.5    Nessler-Menardi, C.6
  • 54
    • 23144434218 scopus 로고    scopus 로고
    • Androgen receptor down regulation by small interference RNA induces cell growth inhibition in androgen sensitive as well as in androgen independent prostate cancer cells
    • Haag P, Bektic J, Bartsch G, Klocker H, Eder IE. Androgen receptor down regulation by small interference RNA induces cell growth inhibition in androgen sensitive as well as in androgen independent prostate cancer cells. J Steroid Biochem Mol Biol 2005;96:251-8.
    • (2005) J Steroid Biochem Mol Biol , vol.96 , pp. 251-258
    • Haag, P.1    Bektic, J.2    Bartsch, G.3    Klocker, H.4    Eder, I.E.5
  • 55
    • 18044362777 scopus 로고    scopus 로고
    • Small-interfering RNA-induced androgen receptor silencing leads to apoptotic cell death in prostate cancer
    • Liao X, Tang S, Thrasher JB, Griebling TL, Li B. Small-interfering RNA-induced androgen receptor silencing leads to apoptotic cell death in prostate cancer. Mol Cancer Ther 2005;4:505-15.
    • (2005) Mol Cancer Ther , vol.4 , pp. 505-515
    • Liao, X.1    Tang, S.2    Thrasher, J.B.3    Griebling, T.L.4    Li, B.5
  • 56
    • 0036170838 scopus 로고    scopus 로고
    • Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells
    • Zegarra-Moro OL, Schmidt LJ, Huang H, Tindall DJ. Disruption of androgen receptor function inhibits proliferation of androgen-refractory prostate cancer cells. Cancer Res 2002;62:1008-13.
    • (2002) Cancer Res , vol.62 , pp. 1008-1013
    • Zegarra-Moro, O.L.1    Schmidt, L.J.2    Huang, H.3    Tindall, D.J.4
  • 57
    • 0032190991 scopus 로고    scopus 로고
    • Evolution of the androgen receptor: Structure-function implications
    • Thornton JW, Kelley DB. Evolution of the androgen receptor: structure-function implications. Bioessays 1998;20:860-9.
    • (1998) Bioessays , vol.20 , pp. 860-869
    • Thornton, J.W.1    Kelley, D.B.2
  • 58
    • 22244455430 scopus 로고    scopus 로고
    • The structural basis of androgen receptor activation: Intramolecular and intermolecular amino-carboxy interactions
    • Schaufele F, Carboneil X, Guerbadot M, Borngraeber S, Chapman MS, Ma AA et al. The structural basis of androgen receptor activation: intramolecular and intermolecular amino-carboxy interactions. Proc Natl Acad Sci U S A 2005;102:9802-7.
    • (2005) Proc Natl Acad Sci U S A , vol.102 , pp. 9802-9807
    • Schaufele, F.1    Carboneil, X.2    Guerbadot, M.3    Borngraeber, S.4    Chapman, M.S.5    Ma, A.A.6
  • 59
    • 43949094975 scopus 로고    scopus 로고
    • Cofactor Restriction by Androgen Receptor N-terminal and C-terminal Interaction
    • Epub ahead of print
    • Toumazou C, Li J, Wong J. Cofactor Restriction by Androgen Receptor N-terminal and C-terminal Interaction. Mol Endocrinol 2007 [Epub ahead of print]
    • (2007) Mol Endocrinol
    • Toumazou, C.1    Li, J.2    Wong, J.3
  • 60
    • 0037155790 scopus 로고    scopus 로고
    • The FXXLF motif mediates androgen receptor-specific interactions with coregulators
    • He B, Minges JT, Lee LW, Wilson EM. The FXXLF motif mediates androgen receptor-specific interactions with coregulators. J Biol Chem 2002;277:10226-35.
    • (2002) J Biol Chem , vol.277 , pp. 10226-10235
    • He, B.1    Minges, J.T.2    Lee, L.W.3    Wilson, E.M.4
  • 61
    • 0025957233 scopus 로고
    • Transcriptional activation and nuclear targeting signals of the human androgen receptor
    • Simental JA, Sar M, Lane MV, French FS, Wilson EM. Transcriptional activation and nuclear targeting signals of the human androgen receptor. J Biol Chem 1991;266:510-8.
    • (1991) J Biol Chem , vol.266 , pp. 510-518
    • Simental, J.A.1    Sar, M.2    Lane, M.V.3    French, F.S.4    Wilson, E.M.5
  • 62
    • 4444288439 scopus 로고    scopus 로고
    • Structural and functional consequences of glutamine tract variation in the androgen receptor
    • Buchanan G, Yang M, Cheong A, Harris JM, Irvine RA, Lambert PF et al. Structural and functional consequences of glutamine tract variation in the androgen receptor. Hum Mol Genet 2004;13:1677-92.
    • (2004) Hum Mol Genet , vol.13 , pp. 1677-1692
    • Buchanan, G.1    Yang, M.2    Cheong, A.3    Harris, J.M.4    Irvine, R.A.5    Lambert, P.F.6
  • 63
    • 12344319442 scopus 로고    scopus 로고
    • Alterations of androgen receptor in prostate cancer
    • Linja MJ, Visakorpi T. Alterations of androgen receptor in prostate cancer. J Steroid Biochem Mol Biol 2004;92:255-64.
    • (2004) J Steroid Biochem Mol Biol , vol.92 , pp. 255-264
    • Linja, M.J.1    Visakorpi, T.2
  • 64
    • 0033178805 scopus 로고    scopus 로고
    • Differential DNA binding by the androgen and glucocorticoid receptors involves the second Zn-finger and a C-terminal extension of the DNA-binding domains
    • Schoenmakers E, Alen P, Verrijdt G, Peeters B, Verhoeven G, Rombauts W et al. Differential DNA binding by the androgen and glucocorticoid receptors involves the second Zn-finger and a C-terminal extension of the DNA-binding domains. Biochem J 1999;341(Pt 3):515-21.
    • (1999) Biochem J , vol.341 , Issue.PART 3 , pp. 515-521
    • Schoenmakers, E.1    Alen, P.2    Verrijdt, G.3    Peeters, B.4    Verhoeven, G.5    Rombauts, W.6
  • 66
    • 0029010368 scopus 로고
    • The basis for half-site specificity explored through a non-cognate steroid receptor-DNA complex
    • Gewirth DT, Sigler PB. The basis for half-site specificity explored through a non-cognate steroid receptor-DNA complex. Nat Struct Biol 1995;2:386-94.
    • (1995) Nat Struct Biol , vol.2 , pp. 386-394
    • Gewirth, D.T.1    Sigler, P.B.2
  • 67
    • 0242637385 scopus 로고    scopus 로고
    • Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth
    • Fu M, Rao M, Wang C, Sakamaki T, Wang J, Di Vizio D et al. Acetylation of androgen receptor enhances coactivator binding and promotes prostate cancer cell growth. Mol Cell Biol 2003;23:8563-75.
    • (2003) Mol Cell Biol , vol.23 , pp. 8563-8575
    • Fu, M.1    Rao, M.2    Wang, C.3    Sakamaki, T.4    Wang, J.5    Di Vizio, D.6
  • 68
    • 19044380048 scopus 로고    scopus 로고
    • Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites
    • Gioeli D, Ficarro SB, Kwiek JJ, Aaronson D, Hancock M, Catling AD et al. Androgen receptor phosphorylation. Regulation and identification of the phosphorylation sites. J Biol Chem 2002;277:29304-14.
    • (2002) J Biol Chem , vol.277 , pp. 29304-29314
    • Gioeli, D.1    Ficarro, S.B.2    Kwiek, J.J.3    Aaronson, D.4    Hancock, M.5    Catling, A.D.6
  • 69
    • 15044349502 scopus 로고    scopus 로고
    • The hinge region of the androgen receptor plays a role in proteasome-mediated transcriptional activation
    • Tanner T, Claessens F, Haelens A. The hinge region of the androgen receptor plays a role in proteasome-mediated transcriptional activation. Ann N Y Acad Sci 2004;1030:587-92.
    • (2004) Ann N Y Acad Sci , vol.1030 , pp. 587-592
    • Tanner, T.1    Claessens, F.2    Haelens, A.3
  • 70
    • 0035942197 scopus 로고    scopus 로고
    • Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone
    • Sack JS, Kish KF, Wang C, Attar RM, Kiefer SE, An Y et al. Crystallographic structures of the ligand-binding domains of the androgen receptor and its T877A mutant complexed with the natural agonist dihydrotestosterone. Proc Natl Acad Sci U S A 2001;98:4904-9.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , pp. 4904-4909
    • Sack, J.S.1    Kish, K.F.2    Wang, C.3    Attar, R.M.4    Kiefer, S.E.5    An, Y.6
  • 71
    • 0142211276 scopus 로고    scopus 로고
    • Identification and characterization of a ligand-regulated nuclear export signal in androgen receptor
    • Saporita AJ, Zhang Q, Navai N, Dincer Z, Hahn J, Cai X et al. Identification and characterization of a ligand-regulated nuclear export signal in androgen receptor. J Biol Chem 2003;278:41998-2005.
    • (2003) J Biol Chem , vol.278 , pp. 41998-42005
    • Saporita, A.J.1    Zhang, Q.2    Navai, N.3    Dincer, Z.4    Hahn, J.5    Cai, X.6
  • 72
    • 15644368237 scopus 로고    scopus 로고
    • Androgen receptor gene amplification: A possible molecular mechanism for androgen deprivation therapy failure in prostate cancer
    • Koivisto P, Kononen J, Palmberg C, Tammela T, Hyytinen E, Isola J et al. Androgen receptor gene amplification: a possible molecular mechanism for androgen deprivation therapy failure in prostate cancer. Cancer Res 1997;57:314-9.
    • (1997) Cancer Res , vol.57 , pp. 314-319
    • Koivisto, P.1    Kononen, J.2    Palmberg, C.3    Tammela, T.4    Hyytinen, E.5    Isola, J.6
  • 73
    • 3843069106 scopus 로고    scopus 로고
    • Androgen receptor: A key molecule in the progression of prostate cancer to hormone independence
    • Taplin ME, Balk SP. Androgen receptor: a key molecule in the progression of prostate cancer to hormone independence. J Cell Biochem 2004;91:483-90.
    • (2004) J Cell Biochem , vol.91 , pp. 483-490
    • Taplin, M.E.1    Balk, S.P.2
  • 74
    • 0042978480 scopus 로고    scopus 로고
    • Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer
    • Edwards J, Krishna NS, Grigor KM, Bartlett JM. Androgen receptor gene amplification and protein expression in hormone refractory prostate cancer. Br J Cancer 2003;89:552-6.
    • (2003) Br J Cancer , vol.89 , pp. 552-556
    • Edwards, J.1    Krishna, N.S.2    Grigor, K.M.3    Bartlett, J.M.4
  • 75
    • 0033767930 scopus 로고    scopus 로고
    • Androgen receptor gene amplification at primary progression predicts response to combined androgen blockade as second line therapy for advanced prostate cancer
    • Palmberg C, Koivisto P, Kakkola L, Tammela TL, Kallioniemi OP, Visakorpi T. Androgen receptor gene amplification at primary progression predicts response to combined androgen blockade as second line therapy for advanced prostate cancer. J Urol 2000;164:1992-5.
    • (2000) J Urol , vol.164 , pp. 1992-1995
    • Palmberg, C.1    Koivisto, P.2    Kakkola, L.3    Tammela, T.L.4    Kallioniemi, O.P.5    Visakorpi, T.6
  • 76
    • 33846910473 scopus 로고    scopus 로고
    • Androgen receptor amplification is associated with increased cell proliferation in prostate cancer
    • Haapala K, Kuukasjarvi T, Hyytinen E, Rantala I, Helin HJ, Koivisto PA. Androgen receptor amplification is associated with increased cell proliferation in prostate cancer. Hum Pathol 2007;38:474-8.
    • (2007) Hum Pathol , vol.38 , pp. 474-478
    • Haapala, K.1    Kuukasjarvi, T.2    Hyytinen, E.3    Rantala, I.4    Helin, H.J.5    Koivisto, P.A.6
  • 77
    • 0032759477 scopus 로고    scopus 로고
    • Androgen receptor gene alterations and chromosomal gains and losses in prostate carcinomas appearing during finasteride treatment for benign prostatic hyperplasia
    • Koivisto PA, Schleutker J, Helin H, Ehren-van Eekelen C, Kallioniemi OP, Trapman J. Androgen receptor gene alterations and chromosomal gains and losses in prostate carcinomas appearing during finasteride treatment for benign prostatic hyperplasia. Clin Cancer Res 1999;5:3578-82.
    • (1999) Clin Cancer Res , vol.5 , pp. 3578-3582
    • Koivisto, P.A.1    Schleutker, J.2    Helin, H.3    Ehren-van Eekelen, C.4    Kallioniemi, O.P.5    Trapman, J.6
  • 79
    • 0029825669 scopus 로고    scopus 로고
    • Codon 877 mutation in the androgen receptor gene in advanced prostate cancer: Relation to antiandrogen withdrawal syndrome
    • Suzuki H, Akakura K, Komiya A, Aida S, Akimoto S, Shimazaki J. Codon 877 mutation in the androgen receptor gene in advanced prostate cancer: relation to antiandrogen withdrawal syndrome. Prostate 1996;29:153-8.
    • (1996) Prostate , vol.29 , pp. 153-158
    • Suzuki, H.1    Akakura, K.2    Komiya, A.3    Aida, S.4    Akimoto, S.5    Shimazaki, J.6
  • 80
    • 0033152164 scopus 로고    scopus 로고
    • Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist
    • Taplin ME, Bubley GJ, Ko YJ, Small EJ, Upton M, Rajeshkumar B et al. Selection for androgen receptor mutations in prostate cancers treated with androgen antagonist. Cancer Res 1999;59:2511-5.
    • (1999) Cancer Res , vol.59 , pp. 2511-2515
    • Taplin, M.E.1    Bubley, G.J.2    Ko, Y.J.3    Small, E.J.4    Upton, M.5    Rajeshkumar, B.6
  • 81
    • 0025644325 scopus 로고
    • A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens
    • Veldscholte J, Ris-Stalpers C, Kuiper GG, Jenster G, Berrevoets C, Claassen E et al. A mutation in the ligand binding domain of the androgen receptor of human LNCaP cells affects steroid binding characteristics and response to anti-androgens. Biochem Biophys Res Commun 1990;173:534-40.
    • (1990) Biochem Biophys Res Commun , vol.173 , pp. 534-540
    • Veldscholte, J.1    Ris-Stalpers, C.2    Kuiper, G.G.3    Jenster, G.4    Berrevoets, C.5    Claassen, E.6
  • 82
    • 17744378148 scopus 로고    scopus 로고
    • Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function
    • Buchanan G, Yang M, Harris JM, Nahm HS, Han G, Moore N et al. Mutations at the boundary of the hinge and ligand binding domain of the androgen receptor confer increased transactivation function. Mol Endocrinol 2001;15:46-56.
    • (2001) Mol Endocrinol , vol.15 , pp. 46-56
    • Buchanan, G.1    Yang, M.2    Harris, J.M.3    Nahm, H.S.4    Han, G.5    Moore, N.6
  • 83
    • 0036645414 scopus 로고    scopus 로고
    • Molecular biology of the androgen receptor
    • Gelmann EP. Molecular biology of the androgen receptor. J Clin Oncol 2002;20:3001-15.
    • (2002) J Clin Oncol , vol.20 , pp. 3001-3015
    • Gelmann, E.P.1
  • 84
    • 0033601249 scopus 로고    scopus 로고
    • Activation function 2 in the human androgen receptor ligand binding domain mediates interdomain communication with the NH(2)-terminal domain
    • He B, Kemppainen JA, Voegel JJ, Gronemeyer H, Wilson EM. Activation function 2 in the human androgen receptor ligand binding domain mediates interdomain communication with the NH(2)-terminal domain. J Biol Chem 1999;274:37219-25.
    • (1999) J Biol Chem , vol.274 , pp. 37219-37225
    • He, B.1    Kemppainen, J.A.2    Voegel, J.J.3    Gronemeyer, H.4    Wilson, E.M.5
  • 85
    • 0030669765 scopus 로고    scopus 로고
    • Interaction between the amino- and carboxyl-terminal regions of the rat androgen receptor modulates transcriptional activity and is influenced by nuclear receptor coactivators
    • Ikonen T, Palvimo JJ, Janne OA. Interaction between the amino- and carboxyl-terminal regions of the rat androgen receptor modulates transcriptional activity and is influenced by nuclear receptor coactivators. J Biol Chem 1997;272:29821-8.
    • (1997) J Biol Chem , vol.272 , pp. 29821-29828
    • Ikonen, T.1    Palvimo, J.J.2    Janne, O.A.3
  • 88
    • 0035815749 scopus 로고    scopus 로고
    • Hormone status selects for spontaneous somatic androgen receptor variants that demonstrate specific ligand and cofactor dependent activities in autochthonous prostate cancer
    • Han G, Foster BA, Mistry S, Buchanan G, Harris JM, Tilley WD et al. Hormone status selects for spontaneous somatic androgen receptor variants that demonstrate specific ligand and cofactor dependent activities in autochthonous prostate cancer. J Biol Chem 2001;276:11204-13.
    • (2001) J Biol Chem , vol.276 , pp. 11204-11213
    • Han, G.1    Foster, B.A.2    Mistry, S.3    Buchanan, G.4    Harris, J.M.5    Tilley, W.D.6
  • 89
    • 0036786205 scopus 로고    scopus 로고
    • Mechanism of antiandrogen action: Key role of hsp90 in conformational change and transcriptional activity of the androgen receptor
    • Georget V, Terouanne B, Nicolas JC, Sultan C. Mechanism of antiandrogen action: key role of hsp90 in conformational change and transcriptional activity of the androgen receptor. Biochemistry 2002;41:11824-31.
    • (2002) Biochemistry , vol.41 , pp. 11824-11831
    • Georget, V.1    Terouanne, B.2    Nicolas, J.C.3    Sultan, C.4
  • 90
    • 33750452673 scopus 로고    scopus 로고
    • Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1
    • Chen S, Xu Y, Yuan X, Bubley GJ, Balk SP. Androgen receptor phosphorylation and stabilization in prostate cancer by cyclin-dependent kinase 1. Proc Natl Acad Sci U S A 2006;103:15969-74.
    • (2006) Proc Natl Acad Sci U S A , vol.103 , pp. 15969-15974
    • Chen, S.1    Xu, Y.2    Yuan, X.3    Bubley, G.J.4    Balk, S.P.5
  • 91
    • 7944234374 scopus 로고    scopus 로고
    • HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability
    • Mellinghoff IK, Vivanco I, Kwon A, Tran C, Wongvipat J, Sawyers CL. HER2/neu kinase-dependent modulation of androgen receptor function through effects on DNA binding and stability. Cancer Cell 2004;6:517-27.
    • (2004) Cancer Cell , vol.6 , pp. 517-527
    • Mellinghoff, I.K.1    Vivanco, I.2    Kwon, A.3    Tran, C.4    Wongvipat, J.5    Sawyers, C.L.6
  • 92
    • 13744257306 scopus 로고    scopus 로고
    • Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation
    • Gaughan L, Logan IR, Neal DE, Robson CN. Regulation of androgen receptor and histone deacetylase 1 by Mdm2-mediated ubiquitylation. Nucleic Acids Res 2005;33:13-26.
    • (2005) Nucleic Acids Res , vol.33 , pp. 13-26
    • Gaughan, L.1    Logan, I.R.2    Neal, D.E.3    Robson, C.N.4
  • 93
    • 43949115712 scopus 로고    scopus 로고
    • Lady Davis Institute for Medical Research Sir Mortimer B. Davis Jewish General Hospital. The Androgen Receptor Mutations Database World Wide Web Server. Montreal, Quebec, Canada. Last updated 24/07/2007. Available from: http://androgendb.mcgill.ca/.
    • Lady Davis Institute for Medical Research Sir Mortimer B. Davis Jewish General Hospital. The Androgen Receptor Mutations Database World Wide Web Server. Montreal, Quebec, Canada. Last updated 24/07/2007. Available from: http://androgendb.mcgill.ca/.
  • 94
    • 0035496220 scopus 로고    scopus 로고
    • The development of androgen-independent prostate cancer
    • Feldman BJ, Feldman D. The development of androgen-independent prostate cancer. Nat Rev Cancer 2001;1:34-45.
    • (2001) Nat Rev Cancer , vol.1 , pp. 34-45
    • Feldman, B.J.1    Feldman, D.2
  • 95
    • 0035300409 scopus 로고    scopus 로고
    • Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen
    • Gregory CW, Johnson RT Jr, Mohler JL, French FS, Wilson EM. Androgen receptor stabilization in recurrent prostate cancer is associated with hypersensitivity to low androgen. Cancer Res 2001;61:2892-8.
    • (2001) Cancer Res , vol.61 , pp. 2892-2898
    • Gregory, C.W.1    Johnson Jr, R.T.2    Mohler, J.L.3    French, F.S.4    Wilson, E.M.5
  • 96
    • 0035361340 scopus 로고    scopus 로고
    • A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy
    • Gregory CW, He B, Johnson RT, Ford OH, Mohler JL, French FS et al. A mechanism for androgen receptor-mediated prostate cancer recurrence after androgen deprivation therapy. Cancer Res 2001;61:4315-9.
    • (2001) Cancer Res , vol.61 , pp. 4315-4319
    • Gregory, C.W.1    He, B.2    Johnson, R.T.3    Ford, O.H.4    Mohler, J.L.5    French, F.S.6
  • 97
    • 0036246191 scopus 로고    scopus 로고
    • AR possesses an intrinsic hormone-independent transcriptional activity
    • Huang ZQ, Li J, Wong J. AR possesses an intrinsic hormone-independent transcriptional activity. Mol Endocrinol 2002;16:924-37.
    • (2002) Mol Endocrinol , vol.16 , pp. 924-937
    • Huang, Z.Q.1    Li, J.2    Wong, J.3
  • 98
    • 0041633910 scopus 로고    scopus 로고
    • Interrogating androgen receptor function in recurrent prostate cancer
    • Zhang L, Johnson M, Le KH, Sato M, Ilagan R, Iyer M et al. Interrogating androgen receptor function in recurrent prostate cancer. Cancer Res 2003;63:4552-60.
    • (2003) Cancer Res , vol.63 , pp. 4552-4560
    • Zhang, L.1    Johnson, M.2    Le, K.H.3    Sato, M.4    Ilagan, R.5    Iyer, M.6
  • 99
    • 0032052279 scopus 로고    scopus 로고
    • Molecular chaperones and subcellular trafficking of steroid receptors
    • DeFranco DB, Ramakrishnan C, Tang Y. Molecular chaperones and subcellular trafficking of steroid receptors. J Steroid Biochem Mol Biol 1998;65:51-8.
    • (1998) J Steroid Biochem Mol Biol , vol.65 , pp. 51-58
    • DeFranco, D.B.1    Ramakrishnan, C.2    Tang, Y.3
  • 101
    • 2342447986 scopus 로고    scopus 로고
    • Importin 7 and importin alpha/importin beta are nuclear import receptors for the glucocorticoid receptor
    • Freedman ND, Yamamoto KR. Importin 7 and importin alpha/importin beta are nuclear import receptors for the glucocorticoid receptor. Mol Biol Cell 2004;15:2276-86.
    • (2004) Mol Biol Cell , vol.15 , pp. 2276-2286
    • Freedman, N.D.1    Yamamoto, K.R.2
  • 103
    • 0033829607 scopus 로고    scopus 로고
    • 103- Poukka H, Karvonen U, Yoshikawa N, Tanaka H, Palvimo JJ, Janne OA. The RING finger protein SNURF modulates nuclear trafficking of the androgen receptor. J Cell Sci 2000;11 (Pt 17):2991-3001
    • 103- Poukka H, Karvonen U, Yoshikawa N, Tanaka H, Palvimo JJ, Janne OA. The RING finger protein SNURF modulates nuclear trafficking of the androgen receptor. J Cell Sci 2000;11 (Pt 17):2991-3001.
  • 104
    • 0034465595 scopus 로고    scopus 로고
    • Dynamics of intracellular movement and nucleocytoplasmic recycling of the ligand-activated androgen receptor in living cells
    • Tyagi RK, Lavrovsky Y, Ahn SC, Song CS, Chatterjee B, Roy AK. Dynamics of intracellular movement and nucleocytoplasmic recycling of the ligand-activated androgen receptor in living cells. Mol Endocrinol 2000;14:1162-74.
    • (2000) Mol Endocrinol , vol.14 , pp. 1162-1174
    • Tyagi, R.K.1    Lavrovsky, Y.2    Ahn, S.C.3    Song, C.S.4    Chatterjee, B.5    Roy, A.K.6
  • 105
    • 0035856514 scopus 로고    scopus 로고
    • DNA binding domains in diverse nuclear receptors function as nuclear export signals
    • Black BE, Holaska JM, Rastinejad F, Paschal BM. DNA binding domains in diverse nuclear receptors function as nuclear export signals. Curr Biol 2001;11:1749-58.
    • (2001) Curr Biol , vol.11 , pp. 1749-1758
    • Black, B.E.1    Holaska, J.M.2    Rastinejad, F.3    Paschal, B.M.4
  • 107
    • 34047241332 scopus 로고    scopus 로고
    • The Hsp90 inhibitor, 17-AAG, prevents the ligand-independent nuclear localization of androgen receptor in refractory prostate cancer cells
    • Saporita AJ, Ai J, Wang Z. The Hsp90 inhibitor, 17-AAG, prevents the ligand-independent nuclear localization of androgen receptor in refractory prostate cancer cells. Prostate 2007;67:509-20.
    • (2007) Prostate , vol.67 , pp. 509-520
    • Saporita, A.J.1    Ai, J.2    Wang, Z.3
  • 108
    • 35448970531 scopus 로고    scopus 로고
    • Control of androgen receptor signaling in prostate cancer by the cochaperone small glutamine rich tetratricopeptide repeat containing protein alpha
    • Buchanan G, Ricciardelli C, Harris JM, Prescott J, Yu ZC, Jia L et al. Control of androgen receptor signaling in prostate cancer by the cochaperone small glutamine rich tetratricopeptide repeat containing protein alpha. Cancer Res 2007;67:10087-96.
    • (2007) Cancer Res , vol.67 , pp. 10087-10096
    • Buchanan, G.1    Ricciardelli, C.2    Harris, J.M.3    Prescott, J.4    Yu, Z.C.5    Jia, L.6
  • 109
    • 33846603663 scopus 로고    scopus 로고
    • Androgen receptor coregulators and their involvement in the development and progression of prostate cancer
    • Chmelar R, Buchanan G, Need EF, Tilley W, Greenberg NM. Androgen receptor coregulators and their involvement in the development and progression of prostate cancer. Int J Cancer 2006;120:719-33.
    • (2006) Int J Cancer , vol.120 , pp. 719-733
    • Chmelar, R.1    Buchanan, G.2    Need, E.F.3    Tilley, W.4    Greenberg, N.M.5
  • 111
    • 24744440805 scopus 로고    scopus 로고
    • SRC-3 is required for prostate cancer cell proliferation and survival
    • Zhou HJ, Yan J, Luo W, Ayala G, Lin SH, Erdem H et al. SRC-3 is required for prostate cancer cell proliferation and survival. Cancer Res 2005;65:7976-83.
    • (2005) Cancer Res , vol.65 , pp. 7976-7983
    • Zhou, H.J.1    Yan, J.2    Luo, W.3    Ayala, G.4    Lin, S.H.5    Erdem, H.6
  • 113
    • 0042889568 scopus 로고    scopus 로고
    • The roles of protein-protein interactions and protein methylation in transcriptional activation by nuclear receptors and their coactivators
    • Stallcup MR, Kim JH, Teyssier C, Lee YH, Ma H, Chen D. The roles of protein-protein interactions and protein methylation in transcriptional activation by nuclear receptors and their coactivators. J Steroid Biochem Mol Biol 2003;85:139-45.
    • (2003) J Steroid Biochem Mol Biol , vol.85 , pp. 139-145
    • Stallcup, M.R.1    Kim, J.H.2    Teyssier, C.3    Lee, Y.H.4    Ma, H.5    Chen, D.6
  • 115
    • 5044232836 scopus 로고    scopus 로고
    • The androgen receptor co-activator CBP is up-regulated following androgen withdrawal and is highly expressed in advanced prostate cancer
    • Comuzzi B, Nemes C, Schmidt S, Jasarevic Z, Lodde M, Pycha A et al. The androgen receptor co-activator CBP is up-regulated following androgen withdrawal and is highly expressed in advanced prostate cancer. J Pathol 2004;204:159-66.
    • (2004) J Pathol , vol.204 , pp. 159-166
    • Comuzzi, B.1    Nemes, C.2    Schmidt, S.3    Jasarevic, Z.4    Lodde, M.5    Pycha, A.6
  • 116
    • 21344441226 scopus 로고    scopus 로고
    • p300 regulates androgen receptor-independent expression of prostate-specific antigen in prostate cancer cells treated chronically with interleukin-6
    • Debes JD, Comuzzi B, Schmidt LJ, Dehm SM, Culig Z, Tindall DJ. p300 regulates androgen receptor-independent expression of prostate-specific antigen in prostate cancer cells treated chronically with interleukin-6. Cancer Res 2005;65:5965-73.
    • (2005) Cancer Res , vol.65 , pp. 5965-5973
    • Debes, J.D.1    Comuzzi, B.2    Schmidt, L.J.3    Dehm, S.M.4    Culig, Z.5    Tindall, D.J.6
  • 117
    • 0037693192 scopus 로고    scopus 로고
    • Expression of Tip60, an androgen receptor coactivator, and its role in prostate cancer development
    • Halkidou K, Gnanapragasam VJ, Mehta PB, Logan IR, Brady ME, Cook S et al. Expression of Tip60, an androgen receptor coactivator, and its role in prostate cancer development. Oncogene 2003;22:2466-77.
    • (2003) Oncogene , vol.22 , pp. 2466-2477
    • Halkidou, K.1    Gnanapragasam, V.J.2    Mehta, P.B.3    Logan, I.R.4    Brady, M.E.5    Cook, S.6
  • 118
    • 27744544281 scopus 로고    scopus 로고
    • The ErbB3 binding protein Ebp1 interacts with Sin3A to repress E2F1 and AR-mediated transcription
    • Zhang Y, Akinmade D, Hamburger AW. The ErbB3 binding protein Ebp1 interacts with Sin3A to repress E2F1 and AR-mediated transcription. Nucleic Acids Res 2005;33:6024-33.
    • (2005) Nucleic Acids Res , vol.33 , pp. 6024-6033
    • Zhang, Y.1    Akinmade, D.2    Hamburger, A.W.3
  • 119
    • 0037103989 scopus 로고    scopus 로고
    • Repression of androgen receptor mediated transcription by the ErbB-3 binding protein, Ebp1
    • Zhang Y, Fondell JD, Wang Q, Xia X, Cheng A, Lu ML et al. Repression of androgen receptor mediated transcription by the ErbB-3 binding protein, Ebp1. Oncogene 2002;21:5609-18.
    • (2002) Oncogene , vol.21 , pp. 5609-5618
    • Zhang, Y.1    Fondell, J.D.2    Wang, Q.3    Xia, X.4    Cheng, A.5    Lu, M.L.6
  • 120
    • 2442484492 scopus 로고    scopus 로고
    • PIASy-mediated repression of the androgen receptor is independent of sumoylation
    • Gross M, Yang R, Top I, Gasper C, Shuai K. PIASy-mediated repression of the androgen receptor is independent of sumoylation. Oncogene 2004;23:3059-66.
    • (2004) Oncogene , vol.23 , pp. 3059-3066
    • Gross, M.1    Yang, R.2    Top, I.3    Gasper, C.4    Shuai, K.5
  • 122
    • 85047683640 scopus 로고    scopus 로고
    • Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor
    • Cheng S, Brzostek S, Lee SR, Hollenberg AN, Balk SP. Inhibition of the dihydrotestosterone-activated androgen receptor by nuclear receptor corepressor. Mol Endocrinol 2002;16:1492-501.
    • (2002) Mol Endocrinol , vol.16 , pp. 1492-1501
    • Cheng, S.1    Brzostek, S.2    Lee, S.R.3    Hollenberg, A.N.4    Balk, S.P.5
  • 124
    • 0029951486 scopus 로고    scopus 로고
    • Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells
    • Yeh S, Chang C. Cloning and characterization of a specific coactivator, ARA70, for the androgen receptor in human prostate cells. Proc Natl Acad Sci U S A 1996;93:5517-21.
    • (1996) Proc Natl Acad Sci U S A , vol.93 , pp. 5517-5521
    • Yeh, S.1    Chang, C.2
  • 125
    • 4043079954 scopus 로고    scopus 로고
    • Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer
    • Hu YC, Yeh S, Yeh SD, Sampson ER, Huang J, Li P et al. Functional domain and motif analyses of androgen receptor coregulator ARA70 and its differential expression in prostate cancer. J Biol Chem 2004;279:33438-46.
    • (2004) J Biol Chem , vol.279 , pp. 33438-33446
    • Hu, Y.C.1    Yeh, S.2    Yeh, S.D.3    Sampson, E.R.4    Huang, J.5    Li, P.6
  • 126
    • 33947223234 scopus 로고    scopus 로고
    • Prostate cancer cells increase androgen sensitivity by increase in nuclear androgen receptor and androgen receptor coactivators; a possible mechanism of hormone-resistance of prostate cancer cells
    • Fujimoto N, Miyamoto H, Mizokami A, Harada S, Nomura M, Ueta Y et al. Prostate cancer cells increase androgen sensitivity by increase in nuclear androgen receptor and androgen receptor coactivators; a possible mechanism of hormone-resistance of prostate cancer cells. Cancer Invest 2007;25:32-7.
    • (2007) Cancer Invest , vol.25 , pp. 32-37
    • Fujimoto, N.1    Miyamoto, H.2    Mizokami, A.3    Harada, S.4    Nomura, M.5    Ueta, Y.6
  • 127
    • 0037627737 scopus 로고    scopus 로고
    • Inactivation of androgen receptor coregulator ARA55 inhibits androgen receptor activity and agonist effect of antiandrogens in prostate cancer cells
    • Rahman MM, Miyamoto H, Lardy H, Chang C. Inactivation of androgen receptor coregulator ARA55 inhibits androgen receptor activity and agonist effect of antiandrogens in prostate cancer cells. Proc Natl Acad Sci U S A 2003;100:5124-9.
    • (2003) Proc Natl Acad Sci U S A , vol.100 , pp. 5124-5129
    • Rahman, M.M.1    Miyamoto, H.2    Lardy, H.3    Chang, C.4
  • 128
    • 33847067142 scopus 로고    scopus 로고
    • Hic-5/ARA55: A prostate stroma-specific AR coactivator
    • Heitzer MD, DeFranco DB. Hic-5/ARA55: a prostate stroma-specific AR coactivator. Steroids 2007;72:218-20.
    • (2007) Steroids , vol.72 , pp. 218-220
    • Heitzer, M.D.1    DeFranco, D.B.2
  • 129
    • 0042671452 scopus 로고    scopus 로고
    • Expression of androgen receptor coactivators in normal and cancer prostate tissues and cultured cell lines
    • Mestayer C, Blanchere M, Jaubert F, Dufour B, Mowszowicz I. Expression of androgen receptor coactivators in normal and cancer prostate tissues and cultured cell lines. Prostate 2003;56:192-200.
    • (2003) Prostate , vol.56 , pp. 192-200
    • Mestayer, C.1    Blanchere, M.2    Jaubert, F.3    Dufour, B.4    Mowszowicz, I.5
  • 130
    • 0041730569 scopus 로고    scopus 로고
    • Expression of AR associated protein 55 (ARA55) and androgen receptor in prostate cancer
    • Miyoshi Y, Ishiguro H, Uemura H, Fujinami K, Miyamoto H, Miyoshi Y et al. Expression of AR associated protein 55 (ARA55) and androgen receptor in prostate cancer. Prostate 2003;56:280-6.
    • (2003) Prostate , vol.56 , pp. 280-286
    • Miyoshi, Y.1    Ishiguro, H.2    Uemura, H.3    Fujinami, K.4    Miyamoto, H.5    Miyoshi, Y.6
  • 131
    • 0036791444 scopus 로고    scopus 로고
    • Heterogeneous expression and functions of androgen receptor co-factors in primary prostate cancer
    • Li P, Yu X, Ge K, Melamed J, Roeder RG, Wang Z. Heterogeneous expression and functions of androgen receptor co-factors in primary prostate cancer. Am J Pathol 2002;161:1467-74.
    • (2002) Am J Pathol , vol.161 , pp. 1467-1474
    • Li, P.1    Yu, X.2    Ge, K.3    Melamed, J.4    Roeder, R.G.5    Wang, Z.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.