SNP haplotypes and allele frequencies show evidence for disruptive and balancing selection in the human leukocyte receptor complex

Immunogenetics

Volumn 56, Issue 4, 2004, Pages 225-237

  Norman, Paul J ^a   Cook, Mark A ^b,c   Carey, B Sean ^a,d   Carrington, Christine V F ^e   Verity, David H ^f   Hameed, Kamran ^g   Ramdath, D Dan ^e   Chandanayingyong, Dasnayanee ^h   Leppert, Mark ⁱ   Stephens, Henry A F ^a,d   Vaughan, R W ^a  

^a GUY S HOSPITAL   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

^c NHS BLOOD AND TRANSPLANT   (United Kingdom)

^d INSTITUTE OF UROLOGY AND NEPHROLOGY   (United Kingdom)

^e UNIVERSITY OF THE WEST INDIES   (Trinidad and Tobago)

^f ST THOMAS HOSPITAL   (United Kingdom)

^g AGA KHAN UNIVERSITY HOSPITAL   (Pakistan)

^h MAHIDOL UNIVERSITY   (Thailand)

ⁱ UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

Author keywords

Haplotype; KIR; Leukocyte receptor complex; Natural killer cell; Natural selection; SNP

Indexed keywords

CELL RECEPTOR; IMMUNOGLOBULIN RECEPTOR; LEUKOCYTE RECEPTOR COMPLEX; UNCLASSIFIED DRUG;

ARTICLE; ASIAN; CAUCASIAN; CHROMOSOME 19Q; CONTROLLED STUDY; GENE FREQUENCY; GENE LINKAGE DISEQUILIBRIUM; GENETIC HETEROGENEITY; GENETIC RECOMBINATION; GENOTYPE; HAPLOTYPE; HUMAN; HUMAN CELL; KILLER CELL; MARKER GENE; NATURAL SELECTION; NEGRO; NORMAL HUMAN; PRIORITY JOURNAL; RECEPTOR GENE; SINGLE NUCLEOTIDE POLYMORPHISM;

EID: 4344660106     PISSN: 00937711     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00251-004-0674-1     Document Type: Article

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